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  1. Book ; Online ; E-Book: Neurologic disease

    Meyer, Michael Andrew

    a modern pathophysiologic approach to diagnosis and treatment

    2016  

    Author's details Michael Andrew Meyer
    Subject code 616.8
    Language English
    Size 1 Online-Ressource (ix, 260 Seiten), 323 Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019077535
    ISBN 978-3-319-39581-4 ; 9783319395791 ; 3-319-39581-5 ; 3319395793
    DOI 10.1007/978-3-319-39581-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Pharmacist optimization of lipid therapy in patients with peripheral vascular disease.

    Tucker, Mary-Ashlyn / Meyer, Andrew / Bitonti, Michael / Supple, Megan / Cain, Brandon

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2024  

    Abstract: Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and ...

    Abstract Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
    Purpose: American College of Cardiology/American Heart Association guidelines recommend high-intensity statin therapy and consideration for nonstatin therapy for patients with peripheral vascular disease (PVD); however, utilization rates remain suboptimal. The primary objective of this study was to determine whether pharmacist intervention for patients with PVD could improve the percentage of patients discharged on a high-intensity statin.
    Methods: The study used a single-center pre/post design and included patients with PVD who underwent peripheral bypass during their admission. Postintervention patients managed with an order set including a preselected consult for a pharmacy lipid protocol were compared to preintervention patients managed using the order set without the consult. The primary outcome was the percentage of patients discharged on a high-intensity statin. Secondary outcomes included intensification of statin therapy, the addition of ezetimibe, and referral to an outpatient lipid clinic.
    Results: A total of 175 patients were included in the analysis, with 94 patients in the preintervention group and 81 patients in the postintervention group. The primary outcome met statistical significance, with an increase in the percentage of patients discharged on a high-intensity statin in the postintervention group (70.4%) compared to the preintervention group (38.3%) (P < 0.001; 95% confidence interval, 1.37-2.46). Secondary outcomes that met statistical significance included an increase in the percentage of patients with any increase in statin intensity (35.8% vs 20.2%; P = 0.02).
    Conclusion: The addition of a pharmacist consult led to an increase in the percentage of patients discharged on a high-intensity statin and an increase in overall statin intensification.
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxae097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Softer Is Better for Titanium: Molecular Titanium Arsenido Anions Featuring Ti≡As Bonding and a Terminal Parent Arsinidene.

    Bhunia, Mrinal / Mohar, Jacob S / Sandoval-Pauker, Christian / Fehn, Dominik / Yang, Eric S / Gau, Michael / Goicoechea, Jose / Ozarowski, Andrew / Krzystek, J / Telser, Joshua / Meyer, Karsten / Mindiola, Daniel J

    Journal of the American Chemical Society

    2024  Volume 146, Issue 6, Page(s) 3609–3614

    Abstract: We introduce the arsenido ligand onto the ... ...

    Abstract We introduce the arsenido ligand onto the Ti
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c12939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  4. Article: Radiation-induced myofibroblastoma within the nasal sinus requiring maxillectomy and ethmoidectomy: A case report and literature review.

    Meyer, David B / Larkins, Michael C / Klose, Charles / Maher, Mohammed / Zeches, Breann A / Brodish, Brian N / Ju, Andrew W / Prenshaw, Karyn

    Clinical case reports

    2023  Volume 11, Issue 1, Page(s) e6546

    Abstract: We report a case of radiation-induced myofibroblastoma of the right nasal cavity in a patient with a remote history of radiotherapy for pediatric retinoblastoma. The patient required maxillectomy and ethmoidectomy. To our knowledge, a rare number of ... ...

    Abstract We report a case of radiation-induced myofibroblastoma of the right nasal cavity in a patient with a remote history of radiotherapy for pediatric retinoblastoma. The patient required maxillectomy and ethmoidectomy. To our knowledge, a rare number of cases have been reported in this location.
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Neurologic disease

    Meyer, Michael Andrew

    a modern pathophysiologic approach to diagnosis and treatment

    2016  

    Author's details Michael Andrew Meyer
    MeSH term(s) Nervous System Diseases/physiopathology
    Language English
    Size ix, 260 pages :, illustrations, portraits
    Document type Book
    ISBN 9783319395791 ; 9783319395814 ; 3319395793 ; 3319395815
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: Bacterial epiglottitis superimposed on oropharyngeal cancer: A case report.

    Larkins, Michael C / Meyer, David B / Lowery, Kenneth / Speicher, Rachel L / Brodish, Brian N / Ju, Andrew W

    Cancer reports (Hoboken, N.J.)

    2023  Volume 6, Issue 3, Page(s) e1783

    Abstract: Background: Patients undergoing chemotherapy and radiotherapy are placed in an immunocompromised state worth consideration in the event of potential airway compromise, especially when superimposed on an airway-obstructing tumor. We report a case of ... ...

    Abstract Background: Patients undergoing chemotherapy and radiotherapy are placed in an immunocompromised state worth consideration in the event of potential airway compromise, especially when superimposed on an airway-obstructing tumor. We report a case of bacterial epiglottitis in a patient with active oropharyngeal cancer (OPC), who presented in such a way that an infectious etiology was not initially considered in the patient's care. To our knowledge, such a circumstance has not been reported in the literature.
    Case: Here, we report a case of a 68-year-old male with advanced-stage OPC who developed respiratory distress and underwent emergent tracheostomy. The patient was diagnosed postoperatively with Haemophilus influenza and Pseudomonas aerugeniosa. Following antibiotic treatment, the patient recovered to the point in which he could then undergo concomitant chemoradiation. The patient later had a recurrence of P. aerugeniosa during their radiotherapy that was also treated with antibiotics. The patient experienced continued symptoms related to their OPC and underwent pharyngectomy. Despite the initial success of this procedure, the patient experienced tumor recurrence and succumbed to his disease.
    Conclusion: This case underscores the importance of considering multiple etiologies concerning airway compromise, as the consequence of delayed cancer treatment may be loss of local cancer control.
    MeSH term(s) Male ; Humans ; Aged ; Epiglottitis/complications ; Epiglottitis/diagnosis ; Epiglottitis/therapy ; Neoplasm Recurrence, Local/drug therapy ; Oropharyngeal Neoplasms/complications ; Oropharyngeal Neoplasms/diagnosis ; Oropharyngeal Neoplasms/therapy ; Chemoradiotherapy/adverse effects ; Tracheostomy/adverse effects ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Case Reports
    ISSN 2573-8348
    ISSN (online) 2573-8348
    DOI 10.1002/cnr2.1783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Divalent Titanium via Reductive N-C Coupling of a TiIV Nitrido with π-Acids.

    Bhunia, Mrinal / Sandoval-Pauker, Christian / Fehn, Dominik / Grant, Lauren / Senthil, Shuruthi / Gau, Michael / Ozarowski, Andrew / Krzystek, Jurek / Telser, Joshua / Pinter, Balazs / Meyer, Karsten / Mindiola, Daniel J

    Angewandte Chemie (International ed. in English)

    2024  , Page(s) e202404601

    Abstract: The nitrido-ate complex [(PN)2Ti(N){μ2-K(OEt2)}]2 (1) reductively couples CO and isocyanides in the presence of DME or cryptand, to form rare, five-coordinate TiII complexes having a linear cumulene motif, [K(L)][(PN)2Ti(NCE)] (E = O, L = Kryptofix222, ( ... ...

    Abstract The nitrido-ate complex [(PN)2Ti(N){μ2-K(OEt2)}]2 (1) reductively couples CO and isocyanides in the presence of DME or cryptand, to form rare, five-coordinate TiII complexes having a linear cumulene motif, [K(L)][(PN)2Ti(NCE)] (E = O, L = Kryptofix222, (2); E = NAd, L = 3 DME, (3); E = NtBu, L = 3 DME, (4); E = NAd, L = Kryptofix222, (5)). Oxidation of 2-5 with [Fc][OTf] afforded an isostructural TiIII center containing a neutral cumulene [(PN)2Ti(NCE)] (E = O, (6); E = NAd (7), NtBu (8)). Moreover, 1e- reduction of 6 and 7 in the presence of cryptand cleanly reformed corresponding discrete TiII complexes 2 and 5, which were further characterized by solution magnetization measurements and high- frequency and -field EPR (HFEPR) spectroscopy. Furthermore, oxidation of 7 with [Fc*][B(C6F5)4] resulted in a ligand disproportionated TiIV complex having transoid carbodiimides, [(PN)2Ti(NCNAd)2] (9). Comparison of spectroscopic, structural, and computational data for the divalent, trivalent, and tetravalent systems, including their 15N enriched isotopomers demonstrate these cumulenes to decrease in order of backbonding as TiII→TiIII→TiIV and increasing order of p-donation as TiII→TiIII→TiIV, thus displaying more covalency in TiIII species. Lastly, we show a synthetic cycle whereby complex 1 can deliver an N-atom to π-acids.
    Language English
    Publishing date 2024-04-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202404601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pediatric influenza vaccination in the perioperative setting: A quality improvement project.

    Meyer, Andrew J / Smith, Jill R / Wright, Tara L / Engler, Laurie J / Bigham, Michael T / Bhalla, Tarun

    Paediatric anaesthesia

    2023  Volume 34, Issue 2, Page(s) 167–174

    Abstract: Introduction/background: Unmet need for seasonal influenza vaccination administration to pediatric patients exists at national and local levels. Vaccination during the perioperative period remains controversial, though opportunity exists to meet ... ...

    Abstract Introduction/background: Unmet need for seasonal influenza vaccination administration to pediatric patients exists at national and local levels. Vaccination during the perioperative period remains controversial, though opportunity exists to meet vaccination need through perioperative programs. The initial SMART Aim of this quality improvement initiative was to establish and increase seasonal influenza vaccination rate in eligible patients during in person preoperative clinic visits in a pediatric perioperative surgical home (PSH) to 10%. Informed by each prior season's experience, we increased our SMART Aim target for vaccinations in seasons two and three to 15 and 18%, respectively.
    Methods: Following the Model for Improvement methodology, the PSH team developed and implemented a perioperative pediatric influenza vaccination program. Across three influenza seasons, key interventions included updates to organizational perioperative vaccination policy, obtaining material influenza vaccination supplies, development of EHR tools, PSH staff education, and communication with patient-families. Rate of eligible patients receiving influenza vaccination at their PSH clinic appointment was tracked over time. Influenza vaccination rates were reported monthly during Season 1, then weekly during seasons two and three. The balancing measure was same day surgery case cancellations related to influenza vaccination given at PSH clinic appointment. Statistical analysis methods utilized include Shewart's control chart and statistical process control (SPC) standards. Special cause variation was determined by eight or more consecutive data points above or below the centerline.
    Results: The influenza vaccination rates in each of the three influenza seasons exceeded vaccination rate goals of 10, 15, and 18%, respectively. A total of 695 vaccines have been administered since program inception. No same day surgical case cancellations were observed as balancing measure.
    Conclusions: Over three consecutive influenza vaccination seasons, we safely established and met vaccination rate goals of 10, 15, and 18% to eligible patients during preoperative clinic visits within a pediatric PSH system. Through iterative PDSA cycles, we continue to identify opportunities for future improvement. This suggests that the perioperative period presents opportunity for seasonal influenza vaccination with potential program expansion to include routine vaccines of childhood.
    MeSH term(s) Child ; Humans ; Influenza, Human/prevention & control ; Quality Improvement ; Influenza Vaccines ; Vaccination ; Seasons
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2023-11-13
    Publishing country France
    Document type Journal Article
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.14790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3306: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Delayed post-hypoxic leukoencephalopathy: case report with a review of disease pathophysiology.

    Meyer, Michael Andrew

    Neurology international

    2013  Volume 5, Issue 3, Page(s) e13

    Abstract: Delayed post-hypoxic leukoencephalopathy is a rare clinical phenomenon usually observed in a small number of carbon monoxide poisoning survivors. A similar phenomenon is reported here in a patient who successfully recovered from a large overdose of ... ...

    Abstract Delayed post-hypoxic leukoencephalopathy is a rare clinical phenomenon usually observed in a small number of carbon monoxide poisoning survivors. A similar phenomenon is reported here in a patient who successfully recovered from a large overdose of diazepam and methadone, but then abruptly declined 3 weeks after the initial event. Magnetic resnance revealed confluent white matter hyperintensity on fluid-attenuated inversion recovery and T2 weighted sequences, and spectroscopy revealed elevated peaks in choline, creatinine, and lactate. Analysis and review of the literature suggests this phenomenon occurs on average about 19 days after the initial event. Although the pathophysiology remains obscure, it is noted here that the mean lucid interval coincides approximately with the replacement half-life for myelin related lipids and proteins.
    Language English
    Publishing date 2013-07-22
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 2514727-4
    ISSN 2035-8377 ; 2035-8385
    ISSN (online) 2035-8377
    ISSN 2035-8385
    DOI 10.4081/ni.2013.e13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Amino Acid Sequences Mediating Vascular Cell Adhesion Molecule 1 Binding to Integrin Alpha 4: Homologous DSP Sequence Found for JC Polyoma VP1 Coat Protein.

    Meyer, Michael Andrew

    Neurology international

    2013  Volume 5, Issue 3, Page(s) e14

    Abstract: The JC polyoma viral coat protein VP1 was analyzed for amino acid sequences homologies to the IDSP sequence which mediates binding of VLA-4 (integrin alpha 4) to vascular cell adhesion molecule 1. Although the full sequence was not found, a DSP sequence ... ...

    Abstract The JC polyoma viral coat protein VP1 was analyzed for amino acid sequences homologies to the IDSP sequence which mediates binding of VLA-4 (integrin alpha 4) to vascular cell adhesion molecule 1. Although the full sequence was not found, a DSP sequence was located near the critical arginine residue linked to infectivity of the virus and binding to sialic acid containing molecules such as integrins (3). For the JC polyoma virus, a DSP sequence was found at residues 70, 71 and 72 with homology also noted for the mouse polyoma virus and SV40 virus. Three dimensional modeling of the VP1 molecule suggests that the DSP loop has an accessible site for interaction from the external side of the assembled viral capsid pentamer.
    Language English
    Publishing date 2013-07-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2514727-4
    ISSN 2035-8377 ; 2035-8385
    ISSN (online) 2035-8377
    ISSN 2035-8385
    DOI 10.4081/ni.2013.e14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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