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  1. Article ; Online: Neurological Complications in COVID-19 Patients and its Implications for Associated Mortality.

    AboTaleb, Hanin A

    Current neurovascular research

    2020  Volume 17, Issue 4, Page(s) 522–530

    Abstract: Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types of genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta ... ...

    Abstract Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types of genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta coronaviruses is reported as lethal zoonotic viruses and has created major epidemic troubles, starting with the severe acute respiratory syndrome (SARS) in 2002, then the Middle East respiratory syndrome (MERS) in 2012, and lastly Coronavirus Disease 2019 (COVID-19) in 2019. However, many neurological complications reported in COVID-19 patients have highlighted a critical pattern of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Awareness of such an association could create new insight to consider neurological manifestations as a COVID-19 differential diagnosis during the pandemic period of COVID-19 to avoid delayed diagnosis and prevent further transmission. This mini-review aims to collect the current knowledge regarding the mechanism behind the neuroinvasive capacity of SARS-CoV-2, to summarize the common documented neurological symptoms and associated complications in COVID-19 patients, and to review the impact of neurological manifestations on COVID-19 mortality.
    MeSH term(s) Animals ; COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/virology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Humans ; Nervous System Diseases/etiology ; Nervous System Diseases/mortality ; Nervous System Diseases/virology ; SARS-CoV-2/pathogenicity
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2296350-9
    ISSN 1875-5739 ; 1567-2026
    ISSN (online) 1875-5739
    ISSN 1567-2026
    DOI 10.2174/1567202617666200727124704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6646: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Neurological Complications in COVID-19 Patients and its Implications for Associated Mortality

    AboTaleb, Hanin A

    Current neurovascular research (Online)

    Abstract: Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta ... ...

    Abstract Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta coronaviruses are reported as lethal zoonotic viruses and have created major epidemic troubles, starting with the severe acute respiratory syndrome (SARS) in 2002, then the Middle East respiratory syndrome (MERS) in 2012, and lastly Coronavirus Disease 2019 (COVID-19) in 2019. However, many neurological complications reported in COVID19 patients have highlighted a critical pattern of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Awareness of such an association could create new insight to consider neurological manifestations as a COVID-19 differential diagnosis during the pandemic period of COVID-19, to avoid delayed diagnosis and prevent further transmission.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #688646
    Database COVID19

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  3. Article ; Online: Neurological Complications in COVID-19 Patients and its Implications for Associated Mortality

    AboTaleb, Hanin A.

    Current Neurovascular Research

    2020  Volume 17

    Abstract: Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta ... ...

    Abstract : Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta coronaviruses are reported as lethal zoonotic viruses and have created major epidemic troubles, starting with the severe acute respiratory syndrome (SARS) in 2002, then the Middle East respiratory syndrome (MERS) in 2012, and lastly Coronavirus Disease 2019 (COVID-19) in 2019. However, many neurological complications reported in COVID19 patients have highlighted a critical pattern of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Awareness of such an association could create new insight to consider neurological manifestations as a COVID-19 differential diagnosis during the pandemic period of COVID-19, to avoid delayed diagnosis and prevent further transmission.
    Keywords Developmental Neuroscience ; Cellular and Molecular Neuroscience ; Neurology ; covid19
    Language English
    Publisher Bentham Science Publishers Ltd.
    Publishing country nl
    Document type Article ; Online
    ZDB-ID 2296350-9
    ISSN 1567-2026
    ISSN 1567-2026
    DOI 10.2174/1567202617666200727124704
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6646: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Depression, anxiety and stress in Saudi migraine patients using DASS-21: local population-based cross-sectional survey.

    Al-Hayani, Majed / AboTaleb, Hanin / Bazi, Abdulrahman / Alghamdi, Badrah

    The International journal of neuroscience

    2021  Volume 133, Issue 3, Page(s) 248–256

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Female ; Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Male ; Depression/epidemiology ; Anxiety/epidemiology ; Cross-Sectional Studies ; Saudi Arabia/epidemiology ; Stress, Psychological/epidemiology ; Comorbidity ; Migraine Disorders/epidemiology ; Migraine Disorders/psychology ; Prevalence
    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 3061-2
    ISSN 1563-5279 ; 1543-5245 ; 0020-7454
    ISSN (online) 1563-5279 ; 1543-5245
    ISSN 0020-7454
    DOI 10.1080/00207454.2021.1909011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 657: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Psychological Distress During COVID-19 Curfews and Social Distancing in Saudi Arabia: A Cross-Sectional Study.

    Alghamdi, Badrah S / Alatawi, Yasser / Alshehri, Fahad S / Tayeb, Haythum O / AboTaleb, Hanin / Binsalman, Amal

    Frontiers in public health

    2022  Volume 9, Page(s) 792533

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Humans ; Pandemics ; Physical Distancing ; Psychological Distress ; SARS-CoV-2 ; Saudi Arabia/epidemiology
    Language English
    Publishing date 2022-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.792533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex.

    Alghamdi, Badrah Saeed / AboTaleb, Hanin Abdulbaset

    Journal of integrative neuroscience

    2020  Volume 19, Issue 2, Page(s) 229–237

    Abstract: Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most common inflammatory disease of young adults. Up to 65% of multiple sclerosis patients have cognitive impairments such as memory loss and difficulty in ... ...

    Abstract Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most common inflammatory disease of young adults. Up to 65% of multiple sclerosis patients have cognitive impairments such as memory loss and difficulty in understanding and maintaining attention and concentration. Many pharmacological interventions have been used to reverse motor impairments in multiple sclerosis patients; however, none of these drugs improve cognitive function. Melatonin can diffuse through the blood-brain barrier and has well-known antioxidant and anti-inflammatory properties with almost no side effects; it is, therefore, a promising neuroprotective supplement for many neurological diseases, such as multiple sclerosis, Alzheimer's disease, Parkinson's disease, ischemic stroke, and fibromyalgia. However, only some researches have assessed the effect of melatonin on cognitive dysfunction in multiple sclerosis. Here, we evaluated the effects of melatonin supplementation on memory defects induced by cuprizone in a mouse model of multiple sclerosis. Cuprizone (400 mg/kg) and melatonin (80 mg/kg) were administered to SWR/J mice daily for 5 weeks. Open field, tail-flick, and novel object recognition behavioral tests were performed. Also, expression of
    MeSH term(s) Animals ; Behavior, Animal/drug effects ; Cuprizone/administration & dosage ; Cyclic AMP Response Element-Binding Protein/drug effects ; Cyclic AMP Response Element-Binding Protein/metabolism ; Disease Models, Animal ; Disks Large Homolog 4 Protein/drug effects ; Disks Large Homolog 4 Protein/metabolism ; Gene Expression/drug effects ; Melatonin/administration & dosage ; Melatonin/pharmacology ; Memory Disorders/drug therapy ; Memory Disorders/etiology ; Memory Disorders/metabolism ; Mice ; Monoamine Oxidase Inhibitors/administration & dosage ; Multiple Sclerosis/complications ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/pharmacology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism ; Recognition, Psychology/drug effects ; Spatial Learning/drug effects ; Synaptophysin/drug effects ; Synaptophysin/metabolism
    Chemical Substances Cyclic AMP Response Element-Binding Protein ; Disks Large Homolog 4 Protein ; Dlg4 protein, mouse ; Monoamine Oxidase Inhibitors ; Neuroprotective Agents ; Synaptophysin ; Syp protein, mouse ; Cuprizone (5N16U7E0AO) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2020-09-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2136427-8
    ISSN 0219-6352
    ISSN 0219-6352
    DOI 10.31083/j.jin.2020.02.32
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6117: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Psychological Distress During COVID-19 Curfews and Social Distancing in Saudi Arabia

    Badrah S. Alghamdi / Yasser Alatawi / Fahad S. Alshehri / Haythum O. Tayeb / Hanin AboTaleb / Amal Binsalman

    Frontiers in Public Health, Vol

    A Cross-Sectional Study

    2022  Volume 9

    Abstract: Background: Coronavirus disease 2019 (COVID-19) has spread to over 150 countries worldwide. Since the first case of COVID-19 was confirmed in Saudi Arabia, cases have continued to escalate exponentially. The COVID-19 outbreak has had a negative effect on ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) has spread to over 150 countries worldwide. Since the first case of COVID-19 was confirmed in Saudi Arabia, cases have continued to escalate exponentially. The COVID-19 outbreak has had a negative effect on mental health and well-being. The study aimed to investigate the effects of the strict national regulations associated with the COVID-19 pandemic on mental health.Methods: This was a cross-sectional study of a convenience sample of Saudi residents. Saudi residents aged 18 years or older were invited to complete an online questionnaire after one month of a nationwide 24-h curfew between May 6, 2020 and May 13, 2020. We measured psychological distress using the Depression, Anxiety, and Stress Scale-21 (DASS-21). We ran binary logistic regression analyses to detect variables that significantly predicted DASS-21 scores.Results: A sample of 2252 participants was recruited from the general population of Saudi Arabia. The DASS-21 score means and standard deviations for depression and anxiety for the whole sample (10.73 ± 10.29 and 6.98 ± 8.30, respectively) were in the range of mild depression and anxiety. In contrast, the mean DASS-21 stress score was within the normal range (11.97 ± 10.80). The mean stress score for healthcare workers was within the normal range (13.70 ± 10.68) but was significantly higher than the mean score for the public (11.56 ± 10.89; P = 0.0006). Several variables (e.g., age, gender, and history of contact with confirmed COVID-19 cases) were significantly associated with higher DASS-21 scores.Conclusions: The COVID-19 pandemic has created a psychological burden. Therefore, there is an urgent need to implement emergency public health interventions that ameliorate the risk perception of COVID-19 through the dissemination of adequate and targeted health information that could be a successful measure to mitigate the psychological impact of the Covid-19 pandemic.
    Keywords mental health ; public health ; COVID-19 ; psychological distress ; Saudi Arabia ; Public aspects of medicine ; RA1-1270
    Subject code 150
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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