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  1. Article: Paroxysmal Atrial Fibrillation (PFA) Detection With Cardiac Monitoring Devices Implanted by Neurologists in Patients With Embolic Strokes of Undetermined Source (ESUS).

    Espinosa, Patricio S / Espinosa Del Pozo, Patricio H / Andrade, Nicolas F / Alusma-Hibbert, Kettia

    Cureus

    2023  Volume 15, Issue 12, Page(s) e51168

    Abstract: Introduction Ischemic stroke is among the leading causes of death and disability. Approximately 50% of cryptogenic strokes are embolic strokes of undetermined source (ESUS). The most common cause of ESUS is atrial fibrillation. Therefore, the detection ... ...

    Abstract Introduction Ischemic stroke is among the leading causes of death and disability. Approximately 50% of cryptogenic strokes are embolic strokes of undetermined source (ESUS). The most common cause of ESUS is atrial fibrillation. Therefore, the detection of atrial fibrillation with long-term implantable devices is needed. Neurologists are directly involved with acute and post-acute stroke care and have direct access to the management of stroke patients. Therefore, there is a need for neurologists to recommend, implant, and monitor cardiac implantable devices in patients with ESUS. Methods From November 2022 to October 2023, our group implanted 32 ESUS patients with Confirm Rx™ insertable cardiac monitors (Abbott, USA). Atrial fibrillation detection was supervised and monitored daily. Results In 24 months, atrial fibrillation was detected in 12.5% of patients (four patients), sinus bradycardia in 6.25% of patients (two patients), paroxysmal supraventricular tachycardia in 9.4% of patients (three patients), and asystole in one patient. Conclusion Our study shows that neurologists involved in the treatment of stroke care can safely implant, monitor, and detect atrial fibrillation accurately. Our rate of detection of atrial fibrillation in patients with ESUS was 12.8%, which is consistent with prior studies.
    Language English
    Publishing date 2023-12-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Focus on neuroimaging

    Espinosa, Patricio S. / Smith, Charles D.

    (Neurology self-assessment)

    2009  

    Author's details Patricio S. Espinosa, Charles D. Smith
    Series title Neurology self-assessment
    Keywords Central nervous system diseases - diagnosis ; Diagnostic imaging - methods ; Diagnostic techniques, neurological ; Neurologic examination - methods ; Case reports ; Problems and exercises
    Language English
    Size 1 Online-Ressource (xii, 336 Seiten), Illustrationen
    Edition 1st ed.
    Publisher Wolters Kluwer Health/Lippincott Williams & Wilkins
    Publishing place Philadelphia
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-9912-6 ; 0-7817-9912-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  3. Book: Focus on neuroimaging

    Espinosa, Patricio S. / Smith, Charles D.

    neurology self-assessment

    2009  

    Author's details Patricio S. Espinosa ; Charles D. Smith
    Keywords Central Nervous System Diseases / diagnosis ; Diagnostic Imaging / methods ; Diagnostic Techniques, Neurological ; Neurologic Examination / methods ; Problems and Exercises
    Language English
    Size XII, 336 S. : Ill.
    Publisher Wolters Kluwer, Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    Accompanying material Zugang zu Internetausgabe über Code
    HBZ-ID HT015968917
    ISBN 0-7817-9912-0 ; 978-0-7817-9912-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 2729 order for loan Magazin
    Zugang zu Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  4. Article ; Online: Advancing global health equity: the transformative potential of community-based surveillance in developing countries.

    Izquierdo Condoy, Juan S / Tello-De-la-Torre, Andrea / Espinosa Del Pozo, Patricio / Ortiz-Prado, Esteban

    Frontiers in public health

    2023  Volume 11, Page(s) 1294686

    MeSH term(s) Humans ; Developing Countries ; Global Health ; Health Equity ; Primary Health Care
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1294686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Leber Hereditary Optic Neuropathy: Case Report and Literature Review.

    Filatov, Asia / Khanni, Javed L / Espinosa, Patricio S

    Cureus

    2020  Volume 12, Issue 4, Page(s) e7745

    Abstract: Leber hereditary optic neuropathy (LHON) is a genetic condition that typically presents with unilateral, painless, sub-acute central vision loss followed by contralateral vision loss after a few weeks to months. It is a rare disease that typically ... ...

    Abstract Leber hereditary optic neuropathy (LHON) is a genetic condition that typically presents with unilateral, painless, sub-acute central vision loss followed by contralateral vision loss after a few weeks to months. It is a rare disease that typically affects young adults - men more than women - and is a relatively common cause of blindness. It is due to a mutation in mitochondrial DNA (mtDNA). The majority (more than 95%) of patients have one of three mtDNA point mutations: m.14484T→C, m.3460G→A, or m.11778G→A. These mutations lead to disruption of the mitochondrial respiratory chain activating pro-apoptotic pathways. For reasons unknown, this insult tends to affect the retinal ganglion cells more than any other cell in the body, leading to the disease state. Due to its low prevalence in the United States (1:50,000), this diagnosis is often overlooked, misdiagnosed, and mismanaged, which may exacerbate symptoms. It is essential then for physicians to recognize the presentation of and understand the diagnostic work-up for LHON. In this case report, we present the diagnostic challenges of a patient who presented with progressive vision loss, discuss the various differential diagnoses, review the literature on LHON, and propose an explanatory model for vision loss in patients with LHON.
    Language English
    Publishing date 2020-04-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Proton Pump Inhibitors and Risk of Dementia: A Hypothesis Generated but Not Adequately Tested.

    Azhar, Mishah / Fiedler, Lawrence / Espinosa, Patricio S / Hennekens, Charles H

    American journal of Alzheimer's disease and other dementias

    2021  Volume 36, Page(s) 15333175211062413

    Abstract: We reviewed the evidence on proton pump inhibitors (PPIs) and dementia. PPIs are among the most widely utilized drugs in the world. Dementia affects roughly 5% of the population of the United States (US) and world aged 60 years and older. With respect to ...

    Abstract We reviewed the evidence on proton pump inhibitors (PPIs) and dementia. PPIs are among the most widely utilized drugs in the world. Dementia affects roughly 5% of the population of the United States (US) and world aged 60 years and older. With respect to PPIs and dementia, basic research has suggested plausible mechanisms but descriptive and analytic epidemiological studies are not inconsistent. In addition, a single large-scale randomized trial showed no association. When the evidence is incomplete, it is appropriate for clinicians and researchers to remain uncertain. Regulatory or public health authorities sometimes need to make real-world decisions based on real-world data. When the evidence is complete, then the most rational judgments for individual patients the health of the general public are possible At present, the evidence on PPIs and dementia suggests more reassurance than alarm. Further large-scale randomized evidence is necessary to do so.
    MeSH term(s) Aged ; Dementia/epidemiology ; Humans ; Middle Aged ; Proton Pump Inhibitors/adverse effects
    Chemical Substances Proton Pump Inhibitors
    Language English
    Publishing date 2021-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1283069-0
    ISSN 1938-2731 ; 0895-5336 ; 1082-5207 ; 1533-3175
    ISSN (online) 1938-2731
    ISSN 0895-5336 ; 1082-5207 ; 1533-3175
    DOI 10.1177/15333175211062413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3299: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena?

    Koek, Adriana Y / Espinosa, Patricio S

    Cureus

    2018  Volume 10, Issue 8, Page(s) e3191

    Abstract: Charles Bonnet syndrome (CBS) refers to the experience of visual hallucinations in the context of visual impairment. The underlying pathology may be localized anywhere along the visual pathway from the eye itself to visual cortical centers. It is ... ...

    Abstract Charles Bonnet syndrome (CBS) refers to the experience of visual hallucinations in the context of visual impairment. The underlying pathology may be localized anywhere along the visual pathway from the eye itself to visual cortical centers. It is sometimes compared to phantom limb syndrome; both involve decreased sensory input, as in loss of a limb or declining vision, resulting in overactivity in areas of the brain controlling sensory perception. Definitive diagnostic criteria are still lacking and may vary by discipline. However, the following features are generally agreed upon: visual hallucinations, impaired vision, and intact cognition and insight. Psychiatric symptoms, cognitive decline, and hallucinations of other sensory modalities are often excluded, although this remains an area of debate. Certain non-classic cases of CBS have inspired the designation of atypical CBS, which encompasses a wide spectrum of sensory experiences and associated symptoms. Auditory hallucinations in the hearing-impaired, a well-described phenomenon thought to have a similar pathogenesis, share with CBS the important risk factor of increased age. In patients experiencing both types of hallucinations with deterioration in both sensory domains, the distinction between a CBS variant and two independent processes may not be straightforward. In addition to the ongoing diagnostic dilemma posed by multimodal hallucinations, these phenomena tend to be underreported by patients likely due to concern that they will be diagnosed with mental illness. Although many patients with this condition are indifferent to it, some suffer distress from their hallucinations and would benefit from recognition, reassurance, and in some cases correction of the underlying cause or pharmacologic treatment. Here we present the case of an elderly woman with a history of macular degeneration and chronic hearing loss who experienced complex auditory and visual hallucinations surrounding an episode of severe anxiety. We postulate that her anxiety acted as a precipitant to her hallucinatory experiences and may partially explain their abrupt onset in the absence of other clear pathologic processes. This case serves to reinforce CBS as a possible etiology of visual hallucinations in the elderly population, while also generating discussion of how to classify her particular set of symptoms.
    Language English
    Publishing date 2018-08-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.3191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Advancing global health equity

    Juan S. Izquierdo Condoy / Andrea Tello-De-la-Torre / Patricio Espinosa Del Pozo / Esteban Ortiz-Prado

    Frontiers in Public Health, Vol

    the transformative potential of community-based surveillance in developing countries

    2023  Volume 11

    Keywords community based surveillance ; global health ; community health workers ; low income ; Ecuador ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article: Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy.

    Filatov, Asia / Sharma, Pamraj / Hindi, Fawzi / Espinosa, Patricio S

    Cureus

    2020  Volume 12, Issue 3, Page(s) e7352

    Abstract: Coronavirus disease 2019 (COVID-19) is a pandemic. Neurological complications of COVID-19 have not been reported. Encephalopathy has not been described as a presenting symptom or complication of COVID-19. We report a case of a 74-year-old patient who ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is a pandemic. Neurological complications of COVID-19 have not been reported. Encephalopathy has not been described as a presenting symptom or complication of COVID-19. We report a case of a 74-year-old patient who traveled from Europe to the United States and presented with encephalopathy and COVID-19.
    Keywords covid19
    Language English
    Publishing date 2020-03-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Neurological Complications of COVID-19: Guillain-Barre Syndrome Following Pfizer COVID-19 Vaccine.

    Waheed, Sadia / Bayas, Angel / Hindi, Fawzi / Rizvi, Zufe / Espinosa, Patricio S

    Cureus

    2021  Volume 13, Issue 2, Page(s) e13426

    Abstract: Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, in December 2019, Coronavirus - 19 (COVID-19) has become a global pandemic with multiple neurological complications. In December 2020, two ... ...

    Abstract Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, in December 2019, Coronavirus - 19 (COVID-19) has become a global pandemic with multiple neurological complications. In December 2020, two vaccines have been approved in the United States for the prevention of COVID-19. We report a case of Guillain-Barre Syndrome (GBS) after receiving the first dose of Pfizer - COVID-19 vaccine.
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.13426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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