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  1. Article ; Online: Multicentre collection of uniform data on patients hospitalised for transient ischaemic attack or stroke in the Philippines

    Robert N Gan / Raquel M Alvarez / Maria Teresa Cañete / Christian Oliver Co / Maria Epifania Collantes / Cyrus G Escabillas / John Harold Hiyadan / Dan Neftalie Juangco / Johnny K Lokin / Maria Cristina Macrohon-Valdez / Monique Therese Punsalan / Gemmalynn B Sarapuddin / Rosalina E Picar / Jose Leonard R Pascual V

    BMJ Open, Vol 12, Iss

    the Philippine Neurological Association One Database-Stroke (PNA1DB-Stroke) protocol

    2022  Volume 5

    Keywords Medicine ; R
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Neurological Manifestations in COVID-19 Infection: A Systematic Review and Meta-Analysis.

    Collantes, Maria Epifania V / Espiritu, Adrian I / Sy, Marie Charmaine C / Anlacan, Veeda Michelle M / Jamora, Roland Dominic G

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2020  Volume 48, Issue 1, Page(s) 66–76

    Abstract: Background: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19.: Methods: We conducted ... ...

    Abstract Background: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19.
    Methods: We conducted a systematic review and meta-analysis that included cohort and case series/reports involving a population of patients confirmed with COVID-19 infection and their neurologic manifestations. We searched the following electronic databases until April 18, 2020: PubMed, Embase, Scopus, and World Health Organization database (PROSPERO registration number: CRD42020180658).
    Results: From 403 articles identified, 49 studies involving a total of 6,335 confirmed COVID-19 cases were included. The random-effects modeling analysis for each neurological symptom showed the following proportional point estimates with 95% confidence intervals: "headache" (0.12; 0.10-0.14; I2 = 77%), "dizziness" (0.08; 0.05-0.12; I2 = 82%), "headache and dizziness" (0.09; 0.06-0.13; I2 = 0%), "nausea" (0.07; 0.04-0.11; I2 = 79%), "vomiting" (0.05; 0.03-0.08; I2 = 74%), "nausea and vomiting" (0.06; 0.03-0.11; I2 = 83%), "confusion" (0.05; 0.02-0.14; I2 = 86%), and "myalgia" (0.21; 0.18-0.25; I2 = 85%). The most common neurological complication associated with COVID-19 infection was vascular disorders (n = 23); other associated conditions were encephalopathy (n = 3), encephalitis (n = 1), oculomotor nerve palsy (n = 1), isolated sudden-onset anosmia (n = 1), Guillain-Barré syndrome (n = 1), and Miller-Fisher syndrome (n = 2). Most patients with neurological complications survived (n = 14); a considerable number of patients died (n = 7); and the rest had unclear outcomes (n = 12).
    Conclusion: This review revealed that neurologic involvement may manifest in COVID-19 infection. What has initially been thought of as a primarily respiratory illness has evolved into a wide-ranging multi-organ disease.
    MeSH term(s) Anosmia/etiology ; Anosmia/physiopathology ; Brain Diseases/etiology ; Brain Diseases/physiopathology ; COVID-19/complications ; COVID-19/physiopathology ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/physiopathology ; Cerebral Infarction/etiology ; Cerebral Infarction/physiopathology ; Cerebrovascular Disorders/etiology ; Cerebrovascular Disorders/physiopathology ; Confusion/etiology ; Confusion/physiopathology ; Dizziness/etiology ; Dizziness/physiopathology ; Encephalitis/etiology ; Encephalitis/physiopathology ; Guillain-Barre Syndrome/etiology ; Guillain-Barre Syndrome/physiopathology ; Headache/etiology ; Headache/physiopathology ; Humans ; Myalgia/etiology ; Myalgia/physiopathology ; Nausea/etiology ; Nausea/physiopathology ; Oculomotor Nerve Diseases/etiology ; Oculomotor Nerve Diseases/physiopathology ; SARS-CoV-2 ; Sinus Thrombosis, Intracranial/etiology ; Sinus Thrombosis, Intracranial/physiopathology ; Vomiting/etiology ; Vomiting/physiopathology
    Keywords covid19
    Language English
    Publishing date 2020-07-15
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2020.146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ischaemic stroke in a patient with myasthaenic crisis and antiphospholipid antibody syndrome.

    Diestro, Jose Danilo B / Dorotan, Maria Kristina C / Andal, Vida Margarette D / Tomas, Arnolfo B / Geocadin, Romergryko G / Collantes, Ma Epifania V

    BMJ case reports

    2019  Volume 12, Issue 8

    Abstract: While autoimmune diseases have been frequently found to coexist in the same patients, the co-occurrence of myasthaeniagravis and antiphospholipid antibody syndrome (APAS) has only been reported in eight cases. We present a case of a 46-year-old Filipina ... ...

    Abstract While autoimmune diseases have been frequently found to coexist in the same patients, the co-occurrence of myasthaeniagravis and antiphospholipid antibody syndrome (APAS) has only been reported in eight cases. We present a case of a 46-year-old Filipina who developed ischaemic stroke while admitted at the neurocritical unit for myasthaenic crisis. She was successfully thrombolysed with intravenous recombinant tissue plasminogen activator (rTPA), given a regimen of intravenous Ig and a dose of cyclophosphamide prior to discharge. Extensive workup revealed APAS to be the aetiology of her stroke. Twenty-one months into her follow-up, she is doing well with a modified Rankin Score of 0. Our case suggests that rTPA followed by immunomodulators may be given safely in myasthaenic crisis patients who develop ischaemic stroke. We emphasise the importance of doing a comprehensive neurological evaluation in agitated patients in the critical care unit.
    MeSH term(s) Administration, Intravenous ; Antiphospholipid Syndrome/complications ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/drug therapy ; Brain Ischemia/pathology ; Critical Care/standards ; Female ; Fibrinolytic Agents/administration & dosage ; Fibrinolytic Agents/therapeutic use ; Humans ; Magnetic Resonance Imaging/methods ; Middle Aged ; Myasthenia Gravis/complications ; Stroke/etiology ; Thrombolytic Therapy/methods ; Tissue Plasminogen Activator/administration & dosage ; Tissue Plasminogen Activator/therapeutic use ; Treatment Outcome
    Chemical Substances Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2019-08-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-231239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Neurological Manifestations in COVID-19 Infection: A Systematic Review and Meta-Analysis

    Collantes, Maria Epifania V / Espiritu, Adrian I / Sy, Marie Charmaine C / Anlacan, Veeda Michelle M / Jamora, Roland Dominic G

    Can J Neurol Sci

    Abstract: BACKGROUND: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19. METHODS: We conducted a ... ...

    Abstract BACKGROUND: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19. METHODS: We conducted a systematic review and meta-analysis that included cohort and case series/reports involving a population of patients confirmed with COVID-19 infection and their neurologic manifestations. We searched the following electronic databases until April 18, 2020: PubMed, Embase, Scopus, and World Health Organization database (PROSPERO registration number: CRD42020180658). RESULTS: From 403 articles identified, 49 studies involving a total of 6,335 confirmed COVID-19 cases were included. The random-effects modeling analysis for each neurological symptom showed the following proportional point estimates with 95% confidence intervals: "headache" (0.12; 0.10-0.14; I2 = 77%), "dizziness" (0.08; 0.05-0.12; I2 = 82%), "headache and dizziness" (0.09; 0.06-0.13; I2 = 0%), "nausea" (0.07; 0.04-0.11; I2 = 79%), "vomiting" (0.05; 0.03-0.08; I2 = 74%), "nausea and vomiting" (0.06; 0.03-0.11; I2 = 83%), "confusion" (0.05; 0.02-0.14; I2 = 86%), and "myalgia" (0.21; 0.18-0.25; I2 = 85%). The most common neurological complication associated with COVID-19 infection was vascular disorders (n = 23); other associated conditions were encephalopathy (n = 3), encephalitis (n = 1), oculomotor nerve palsy (n = 1), isolated sudden-onset anosmia (n = 1), Guillain-Barré syndrome (n = 1), and Miller-Fisher syndrome (n = 2). Most patients with neurological complications survived (n = 14); a considerable number of patients died (n = 7); and the rest had unclear outcomes (n = 12). CONCLUSION: This review revealed that neurologic involvement may manifest in COVID-19 infection. What has initially been thought of as a primarily respiratory illness has evolved into a wide-ranging multi-organ disease.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #646255
    Database COVID19

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  5. Article ; Online: Neurological Manifestations in COVID-19 Infection

    Collantes, Maria Epifania V. / Espiritu, Adrian I. / Sy, Marie Charmaine C. / Anlacan, Veeda Michelle M. / Jamora, Roland Dominic G.

    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

    A Systematic Review and Meta-Analysis

    2020  , Page(s) 1–11

    Abstract: ABSTRACT: Background: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19. Methods: We ... ...

    Abstract ABSTRACT: Background: Growing evidence showed that coronavirus disease 2019 (COVID-19) infection may present with neurological manifestations. This review aimed to determine the neurological manifestations and complications in COVID-19. Methods: We conducted a systematic review and meta-analysis that included cohort and case series/reports involving a population of patients confirmed with COVID-19 infection and their neurologic manifestations. We searched the following electronic databases until April 18, 2020: PubMed, Embase, Scopus, and World Health Organization database (PROSPERO registration number: CRD42020180658). Results: From 403 articles identified, 49 studies involving a total of 6,335 confirmed COVID-19 cases were included. The random-effects modeling analysis for each neurological symptom showed the following proportional point estimates with 95% confidence intervals: “headache” (0.12; 0.10–0.14; I 2 = 77%), “dizziness” (0.08; 0.05–0.12; I 2 = 82%), “headache and dizziness” (0.09; 0.06–0.13; I 2 = 0%), “nausea” (0.07; 0.04–0.11; I 2 = 79%), “vomiting” (0.05; 0.03–0.08; I 2 = 74%), “nausea and vomiting” (0.06; 0.03–0.11; I 2 = 83%), “confusion” (0.05; 0.02–0.14; I 2 = 86%), and “myalgia” (0.21; 0.18–0.25; I 2 = 85%). The most common neurological complication associated with COVID-19 infection was vascular disorders ( n = 23); other associated conditions were encephalopathy ( n = 3), encephalitis ( n = 1), oculomotor nerve palsy ( n = 1), isolated sudden-onset anosmia ( n = 1), Guillain–Barré syndrome ( n = 1), and Miller–Fisher syndrome ( n = 2). Most patients with neurological complications survived ( n = 14); a considerable number of patients died ( n = 7); and the rest had unclear outcomes ( n = 12). Conclusion: This review revealed that neurologic involvement may manifest in COVID-19 infection. What has initially been thought of as a primarily respiratory illness has evolved into a wide-ranging multi-organ disease.
    Keywords Neurology ; Clinical Neurology ; General Medicine ; covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2020.146
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1203: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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