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Article ; Online: Standardized documentation and synoptic reporting of complex intestinal anatomy in enteric fistulation and intestinal failure.

Williams, Katherine J / Donnelly, Suzanne / Gabe, Simon / Gupta, Arun / Holman, Richard / Preston, Stephen / Vaizey, Carolynne J / Corr, Alison / Mehta, Akash M

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2021 Volume 24, Issue 4, Page(s) 530–534

Abstract: Aim: In intestinal failure, delineation of both structure and function are key to controlling symptoms and planning further intervention. We have developed a template for developing an 'anatomy at a glance' patient-specific map to aid decision making ... ...

Abstract	Aim: In intestinal failure, delineation of both structure and function are key to controlling symptoms and planning further intervention. We have developed a template for developing an 'anatomy at a glance' patient-specific map to aid decision making and counselling. Method: A core dataset was developed and used to create an editable template to demonstrate the gastrointestinal tract, its relationship to the genitourinary tract, and specific anterior abdominal wall features. This was then used to create an anatomical template, specific to each patient, and stored in the electronic patient record and imaging archive. Results: We have developed a technique for integration of multi-modal information into one diagram, easily referenced by the multidisciplinary team. Radiology, endoscopy and previous operation notes can be used to fill out a core dataset, which is then transposed into a standardized template. A worked example is shown. Conclusion: The mapping template has been successfully integrated into practice and aided decision making at all stages of the patient's therapeutic journey. It has been found helpful in planning routes of nutrition, preoperative optimization, surgical planning, interpreting postoperative imaging and managing patient expectations.
MeSH term(s)	Abdominal Wall/surgery ; Documentation ; Humans ; Intestinal Failure ; Intestine, Small ; Intestines
Language	English
Publishing date	2021-12-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.16007
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Article ; Online: Initial experience with SphinKeeper™ intersphincteric implants for faecal incontinence in the UK: a two-centre retrospective clinical audit.

Leo, C A / Leeuwenburgh, M / Orlando, A / Corr, A / Scott, S M / Murphy, J / Knowles, C H / Vaizey, C J / Giordano, P

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2020 Volume 22, Issue 12, Page(s) 2161–2169

Abstract: Aim: The SphinKeeper™ artificial bowel sphincter implant is a relatively new surgical technique for the treatment of refractory faecal incontinence. This study presents the first experience in two UK tertiary centres.: Method: This is a retrospective ...

Abstract	Aim: The SphinKeeper™ artificial bowel sphincter implant is a relatively new surgical technique for the treatment of refractory faecal incontinence. This study presents the first experience in two UK tertiary centres. Method: This is a retrospective audit of prospectively collected clinical data in relation to technique, safety, feasibility and short-term effectiveness from patients undergoing surgery from January 2016 to April 2019. Baseline data, intra-operative and postoperative complications, symptoms [using St Mark's incontinence score (SMIS)] and radiological outcomes were analysed. Results: Twenty-seven patients [18 women, median age 57 years (range 27-87)] underwent SphinKeeper. In 30% of the patients, the firing device jammed and not all prostheses were delivered. There were no intra-operative complications and all patients were discharged the same or the following day. SMIS significantly improved from baseline [median -6 points (range -12 to +3); P < 0.00016] with 14/27 (51.9%) patients achieving a 50% reduction in the SMIS score. On postoperative imaging, a median of seven prostheses (range 0-10) were identified with a median of five (range 0-10) optimally placed. There was no relationship between number of well-sited prostheses on postoperative imaging and categorical success based on 50% reduction in SMIS (χ Conclusion: SphinKeeper appears to be a safe procedure for faecal incontinence. Overall, about 50% patients achieved a meaningful improvement in symptoms. However, clinical benefit was unrelated to the rate of misplaced/migrated implants. This has implications for confidence in proof of mechanism and also the need for technical refinement.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Anal Canal/surgery ; Clinical Audit ; Fecal Incontinence/surgery ; Female ; Humans ; Middle Aged ; Prostheses and Implants ; Quality of Life ; Retrospective Studies ; Treatment Outcome ; United Kingdom
Language	English
Publishing date	2020-09-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15277
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Article ; Online: Randomized Pilot Study: Anal Inserts Versus Percutaneous Tibial Nerve Stimulation in Patients With Fecal Incontinence.

Leo, Cosimo Alex / Thomas, Gregory P / Hodgkinson, Jonathan D / Leeuwenburgh, Marjolein / Bradshaw, Ellie / Warusavitarne, Janindra / Murphy, Jamie / Vaizey, Carolynne J

Diseases of the colon and rectum

2021 Volume 64, Issue 4, Page(s) 466–474

Abstract: Background: Anal inserts and percutaneous tibial nerve stimulation may be offered to those with fecal incontinence in whom other conservative treatments have failed.: Objective: We aimed to compare anal inserts and percutaneous tibial nerve ... ...

Abstract	Background: Anal inserts and percutaneous tibial nerve stimulation may be offered to those with fecal incontinence in whom other conservative treatments have failed. Objective: We aimed to compare anal inserts and percutaneous tibial nerve stimulation. Design: This was an investigator-blinded randomized pilot study. Settings: The study was conducted at a large tertiary care hospital. Patients: Adult patients with passive or mixed fecal incontinence were recruited. Interventions: Patients were randomly assigned to receive either the anal inserts or weekly percutaneous tibial nerve stimulation for a period of 3 months. Main outcome measures: The primary end point was a 50% reduction of episodes of fecal incontinence per week as calculated by a prospectively completed 2-week bowel diary. Secondary end points were St Mark's incontinence score, International Consultation on Incontinence Questionnaire-Bowel scores (for bowel pattern, bowel control, and quality of life), use of antidiarrheal agents, estimates of comfort and acceptability. Results: Fifty patients were recruited: 25 were randomly assigned to anal inserts and 25 were randomly assigned to percutaneous tibial nerve stimulation. All completed treatment. A significant improvement of scores in the 2-week bowel diary, the St Mark's scores and the International Consultation on Incontinence Questionnaire-Bowel scores, was seen in both groups after 3 months of treatment. A reduction of ≥50% fecal incontinence episodes was reached by 76% (n = 19/25) by the anal insert group, compared with 48% (n = 12/25) of those in the percutaneous tibial nerve stimulation group (p = 0.04). The St Mark's fecal incontinence scores and the International Consultation on Incontinence Questionnaire-Bowel scores for bowel pattern, bowel control, and quality of life (p = 0.01) suggest similar improvement for each group. Limitations: A realistic sample size calculation could not be performed because of the paucity of objective prospective studies assessing the effect of the insert device and percutaneous tibial nerve stimulation. Conclusions: Both anal insert and percutaneous tibial nerve stimulation improved the symptoms of fecal incontinence after 3 months of treatment. The insert device appeared to be more effective than percutaneous tibial nerve stimulation. Larger studies are needed to investigate this further. See Video Abstract at http://links.lww.com/DCR/B460. Trial registration number: Clinicaltrials.gov No. NCT04273009. Estudio piloto aleatorizado de inserciones anales contra la estimulacin percutnea del nervio tibial en pacientes con incontinencia fecal: ANTECEDENTES:Las inserciones anales y la estimulación percutánea del nervio tibial (PTNS) se pueden ofrecer a las personas con incontinencia fecal que han fallado en otros tratamientos conservadores.OBJETIVO:Nuestro objetivo fue comparar inserciones anales y estimulación percutánea del nervio tibial.DISEÑO:Este fue un estudio piloto aleatorio ciego para investigadores.AJUSTE:El estudio se realizó en un hospital de atención terciaria.PACIENTES:Se reclutaron pacientes adultos con incontinencia fecal pasiva o mixta.INTERVENCIONES:Los pacientes fueron asignados al azar para recibir inserciones anales o estimulación del nervio tibial percutáneo semanal durante un período de tres meses.PRINCIPALES MEDIDAS DE RESULTADO:El principal resultado fue una reducción del 50% de los episodios de incontinencia fecal por semana, según lo calculado mediante un diario intestinal de dos semanas completado de forma prospectiva. Los criterios de valoración secundarios fueron la puntuación de incontinencia de St Mark, las puntuaciones del ICIQ-B (para patrón intestinal, control intestinal y calidad de vida), uso de agentes antidiarreicos, estimaciones de comodidad y aceptabilidad.RESULTADOS:Se reclutaron 50 pacientes: 25 fueron asignados al azar a inserciones anales y 25 a PTNS. Todo el tratamiento completado. Se observó una mejora significativa de las puntuaciones en el diario intestinal de dos semanas, la puntuación de St Mark y la puntuación del ICIQ-B en ambos grupos después de 3 meses de tratamiento. Se alcanzó una reducción de ≥ 50% de los episodios de incontinencia fecal en un 76% (n = 19/25) en el grupo de inserción anal, en comparación con el 48% (n = 12/25) de los del grupo de estimulación percutánea del nervio tibial (p = 0,04). Las puntuaciones de incontinencia fecal de St Mark, las puntuaciones del ICIQ-B para el patrón intestinal, el control intestinal y la calidad de vida (p = 0,01) sugieren una mejora similar para cada grupo.LIMITACIONES:No se pudo realizar un cálculo realista del tamaño de la muestra debido a la escasez de estudios prospectivos objetivos que evaluaran el efecto del dispositivo de inserción y la estimulación percutánea del nervio tibial.CONCLUSIONES:Tanto la inserción anal como la estimulación percutánea del nervio tibial mejoraron los síntomas de incontinencia fecal después de 3 meses de tratamiento. El dispositivo de inserción parecia ser más efectivo que la estimulación percutánea del nervio tibial. Se necesitan estudios más amplios para investigar esto más a fondo. Consulte Video Resumen en http://links.lww.com/DCR/B460.NÚMERO DE REGISTRO DE PRUEBA:Clinicaltrials.gov No. NCT04273009.
MeSH term(s)	Adult ; Aged ; Case-Control Studies ; Fecal Incontinence/prevention & control ; Fecal Incontinence/therapy ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Prostheses and Implants/adverse effects ; Prostheses and Implants/statistics & numerical data ; Prosthesis Design/trends ; Prosthesis Implantation/instrumentation ; Prosthesis Implantation/methods ; Prosthesis Implantation/statistics & numerical data ; Quality of Life ; Silicones/adverse effects ; Surveys and Questionnaires ; Tibial Nerve/physiology ; Transcutaneous Electric Nerve Stimulation/methods ; Transcutaneous Electric Nerve Stimulation/statistics & numerical data ; Treatment Outcome
Chemical Substances	Silicones
Language	English
Publishing date	2021-01-05
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial ; Video-Audio Media
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1097/DCR.0000000000001913
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Article ; Online: Incisional hernia and enterocutaneous fistula in patients with chronic intestinal failure: prevalence and risk factors in a cohort of patients referred to a tertiary centre.

Hodgkinson, J D / Oke, S M / Warusavitarne, J / Hanna, G B / Gabe, S M / Vaizey, C J

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2019 Volume 21, Issue 11, Page(s) 1288–1295

Abstract: Aim: This study aims to determine the prevalence of incisional hernia (IH) and enterocutaneous fistula (ECF) in patients with intestinal failure (IF) referred to a tertiary centre and to identify factors associated with their development.: Method: A ... ...

Abstract	Aim: This study aims to determine the prevalence of incisional hernia (IH) and enterocutaneous fistula (ECF) in patients with intestinal failure (IF) referred to a tertiary centre and to identify factors associated with their development. Method: A retrospective case note review was undertaken of a prospectively maintained database of all patients on home parenteral nutrition between 2011 and 2016 at a UK tertiary referral centre for IF. Risk factors were identified using binary logistic regression. Results: The database search identified 447 patients, of whom 349 (78.1%) had surgery prior to developing IF. Eighty-one (23.2%) patients had an IH and 123 (35.2%) had an ECF at the time of referral. Of these, 51 (14.6%) had both IH and ECF. IH was associated with a high body mass index (P = 0.05), a history of a major surgical complication resulting in IF (P = 0.01), previous emergency surgery (P = 0.04), increasing number of operations (P = 0.02) and surgical site infection (SSI; P = 0.01). ECF was associated with complications relating to earlier surgery. (P ≤ .001), previous treatment with an open abdomen (P = 0.03), SSI (P = 0.001), intra-abdominal collection (P ≤ 0.001) and anastomotic leak (P = 0.02). Conclusion: In this series, patients with IF had a prevalence of IH which was more than double that expected following elective laparotomy (about 10%) and one in three had an ECF. Risk factors for IH and ECF are discussed.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Chronic Disease ; Databases, Factual ; Female ; Humans ; Incisional Hernia/epidemiology ; Incisional Hernia/etiology ; Intestinal Diseases/complications ; Intestinal Diseases/surgery ; Intestinal Fistula/epidemiology ; Intestinal Fistula/etiology ; Laparotomy/adverse effects ; Logistic Models ; Male ; Middle Aged ; Parenteral Nutrition, Home/statistics & numerical data ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Prevalence ; Prospective Studies ; Retrospective Studies ; Risk Factors ; Tertiary Care Centers/statistics & numerical data ; United Kingdom/epidemiology ; Young Adult
Language	English
Publishing date	2019-07-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.14735
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Article: Distal feeding-bowel stimulation to treat short-term or long-term pathology: a systematic review.

Dilke, Stella Maye / Gould, Laura / Yao, Mark / Souvatzi, Maria / Stearns, Adam / Ignjatovic-Wilson, Ana / Tozer, Phil / Vaizey, Carolynne J

Frontline gastroenterology

2020 Volume 12, Issue 7, Page(s) 677–682

Abstract: Background: Distal feeding (DF) describes the insertion of a feeding tube into a fistula or stoma to administer a liquid feed into the distal bowel. It is currently used clinically in patients who are unable to absorb enough nutrition orally. This ... ...

Abstract	Background: Distal feeding (DF) describes the insertion of a feeding tube into a fistula or stoma to administer a liquid feed into the distal bowel. It is currently used clinically in patients who are unable to absorb enough nutrition orally. This systematic review investigates DF as a therapeutic measure across a spectrum of patients with stomas and fistulae. Methods: A total of 2825 abstracts and 44 full-text articles were screened via OVID. Fifteen papers were included for analysis. Randomised controlled trials, cohort and observational studies investigating DF as a therapeutic measure were included. Results: Three feeds were used across the studies-reinfusion of effluent, infusion of prebiotic or a mixture. The studies varied the length of feeding between 24 hours and 61 days, and the mode of feeding, bolus or continuous varied.DF was demonstrated to effectively wean patients from parenteral nutrition in two papers. Two papers demonstrated a significant reduction in stoma output. Three papers demonstrated improved postoperative complication rates with distal feeding regimens, including ileus (2.85% vs 20% in unfed population, p=0.024). One paper demonstrated a reduction in postoperative stool frequency. Conclusions: This review was limited by study heterogeneity and the lack of trial data, and in the patient groups involved, the variability in diet and length of regimen. These studies suggest that DF can significantly reduce stoma output and improve renal and liver function; however, the mechanism is not clear. Further mechanistic work on the immunological and microbiological action of DF would be important.
Language	English
Publishing date	2020-08-18
Publishing country	England
Document type	Systematic Review
ZDB-ID	2521857-8
ISSN	2041-4137
ISSN	2041-4137
DOI	10.1136/flgastro-2019-101359
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Article ; Online: Letter: orlistat as a potential treatment for chronic idiopathic constipation.

Iqbal, F / Samuel, M / Tan, E J K / Nicholls, R J / Vaizey, C J

Alimentary pharmacology & therapeutics

2016 Volume 43, Issue 7, Page(s) 848–849

MeSH term(s)	Colectomy/methods ; Constipation/surgery ; Female ; Humans ; Male
Language	English
Publishing date	2016-04
Publishing country	England
Document type	Comment ; Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	639012-2
ISSN	1365-2036 ; 0269-2813 ; 0953-0673
ISSN (online)	1365-2036
ISSN	0269-2813 ; 0953-0673
DOI	10.1111/apt.13555
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Article ; Online: Comparison between high-resolution water-perfused anorectal manometry and THD

Leo, C A / Cavazzoni, E / Leeuwenburgh, M M N / Thomas, G P / Dennis, A / Bassett, P / Hodgkinson, J D / Warusavitarne, J / Murphy, J / Vaizey, C J

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2020 Volume 22, Issue 8, Page(s) 923–930

Abstract: Aim: Anorectal physiology tests provide a functional assessment of the anal canal. The aim of this study was to compare the results generated by standard high-resolution water-perfused manometry (WPM) with the newer THD: Method: This was a ... ...

Abstract	Aim: Anorectal physiology tests provide a functional assessment of the anal canal. The aim of this study was to compare the results generated by standard high-resolution water-perfused manometry (WPM) with the newer THD Method: This was a prospective observational study. Conventional manometry was carried out using a water-perfused catheter with high-resolution manometry and compared with the Anopress system with air-filled catheters. All patients underwent the two procedures successively in a randomized order. Time to arrive at the resting pressure plateau, resting, squeeze, straining pressure and visual analogue scale (VAS) scores for pain were recorded. A qualitative analysis of the two devices was performed. Results: Between 2016 and 2017, 60 patients were recruited. The time from insertion of the catheter to arriving at the resting pressure plateau was significantly lower with the Anopress compared with WPM: 12 s [interquartile range (IQR) 10-17 s] versus 100 s (IQR 67-121 s) (P < 0.001). A strong correlation between the manometric values of WPM and the Anopress was observed. Both procedures were well tolerated, although the VAS score for insertion of the WPM catheter was significantly higher. The Anopress was easier to use and more time-efficient than the WPM. Conclusion: The pressure values obtained with Anopress correlated well with those of conventional manometry. The Anopress has the advantage of being less time-consuming, user-friendly and better tolerated by patients.
MeSH term(s)	Anal Canal ; Anus Diseases ; Catheters ; Fecal Incontinence ; Humans ; Manometry ; Rectum ; Water
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2020-02-21
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.14992
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Article ; Online: The development of a cryptoglandular Anal Fistula Core Outcome Set (AFCOS): an international Delphi study protocol.

Machielsen, A J H M / Iqbal, N / Kimman, M L / Sahnan, K / Adegbola, S O / Kleijnen, J / Vaizey, C J / Grossi, U / Tozer, P J / Breukink, S O

United European gastroenterology journal

2020 Volume 8, Issue 2, Page(s) 220–226

Abstract: Purpose: Cryptoglandular anal fistula is a disorder with an incidence of around 1 per 5,000 people per year in European countries. Many studies have been conducted to evaluate the effectiveness of interventions for anal fistula. However, there is ... ...

Abstract	Purpose: Cryptoglandular anal fistula is a disorder with an incidence of around 1 per 5,000 people per year in European countries. Many studies have been conducted to evaluate the effectiveness of interventions for anal fistula. However, there is considerable heterogeneity in the outcomes assessed and reported in these studies. This limits research quality and complicates evidence synthesis. A solution for heterogeneity in outcome reporting is the development of a Core Outcome Set (COS). This paper describes the protocol for the development of a European COS for Anal Fistula (AFCOS). Methods: The first step will be a systematic review of the literature to identify potential outcomes that may be included in the COS. Patient interviews will be conducted in The United Kingdom and The Netherlands to ensure that both clinician-important and patient-important outcomes are captured. The outcomes will be categorized using the COMET taxonomy and taken forward to a Delphi consensus exercise. In up to three web-based Delphi surveys the outcomes will be prioritized by patients, clinicians (surgeons, gastroenterologists, and radiologists), and (clinical) researchers. The responses will be summarized and reported anonymously in subsequent round(s) facilitating convergence to a consensus opinion. The final COS will be decided during a face-to-face consensus meeting with patients, clinicians, and (clinical) researchers. Discussion: This study protocol describes the development of a European COS for anal fistula to improve research quality, evidence synthesis, and patient care.
Keywords	covid19
Language	English
Publishing date	2020-01-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2728585-6
ISSN	2050-6414 ; 2050-6406
ISSN (online)	2050-6414
ISSN	2050-6406
DOI	10.1177/2050640620907570
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Article ; Online: Quality of life after restorative proctocolectomy in Muslim patients.

Iqbal, Fareed / Zaman, Shafquat / Bowley, Douglas M / Vaizey, Carolynne J

Gut

2014 Volume 63, Issue 7, Page(s) 1197–1198

MeSH term(s)	Humans ; Inflammatory Bowel Diseases/therapy
Language	English
Publishing date	2014-07
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	80128-8
ISSN	1468-3288 ; 0017-5749
ISSN (online)	1468-3288
ISSN	0017-5749
DOI	10.1136/gutjnl-2013-306136
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Article ; Online: A meta-analysis comparing open anterior component separation with posterior component separation and transversus abdominis release in the repair of midline ventral hernias.

Hodgkinson, J D / Leo, C A / Maeda, Y / Bassett, P / Oke, S M / Vaizey, C J / Warusavitarne, J

Hernia : the journal of hernias and abdominal wall surgery

2018 Volume 22, Issue 4, Page(s) 617–626

Abstract: ... for local myofascial advancement in abdominal hernia surgery. PCSTAR, described by Novitsky et al. (Am J ...

Abstract	Purpose: This study aims to compare the outcomes of posterior component separation and transversus abdominis release (PCSTAR) with the open anterior component separation (OACS) technique. OACS, first described by Ramirez et al. (Plast Reconstr Surg 86(3):519-526, 1990), has become an established technique for local myofascial advancement in abdominal hernia surgery. PCSTAR, described by Novitsky et al. (Am J Surg 204(5):709-716, 2012), is being used more frequently and is rapidly becoming the technique of choice in complex ventral hernia repair. Methods: Analysis was conducted according to PRISMA guidelines. A systematic search of the MEDLINE, EMBASE and Pubmed databases was performed. Studies reporting exclusively on midline ventral hernia repair were reviewed. Studies describing PCSTAR were selected and compared to matched studies describing OACS. Meta-analysis was used to compare outcomes between the two-pooled groups. Results: Seven studies describing 281 cases of PCSTAR for midline incisional hernia using a retromuscular mesh placement were identified. Six comparable studies describing 285 cases of OACS and retromuscular mesh placement were identified from the same search. Pooled analysis demonstrated a hernia recurrence rate of 5.7% (3.0-8.5) for PCSTAR and 9.5% (4.0-14.9) for OACS. Comparative analysis demonstrated no significant difference between hernia recurrence rate (p = 0.23). The use of bridging mesh was not significantly reduced by the use of PCSTAR (3.1%) when compared to ACS (7.5%) (p = 0.22). No significant difference was found in wound complication rates between PCSTAR and OACS, respectively, 'superficial' 10.9 vs 21.6% (p = 0.15); and 'deep' 9.5 vs 12.7% (p = 0.53). Conclusions: These data suggest PCSTAR have comparable outcomes to OACS. This analysis is limited by the lack of comparative studies and heterogenicity in the OACS group.
MeSH term(s)	Abdominal Muscles/surgery ; Abdominal Wall/surgery ; Female ; Hernia, Ventral/surgery ; Herniorrhaphy/methods ; Humans ; Incisional Hernia/surgery ; Male ; Middle Aged ; Surgical Mesh
Language	English
Publishing date	2018-03-07
Publishing country	France
Document type	Comparative Study ; Journal Article ; Meta-Analysis ; Review
ZDB-ID	1388125-5
ISSN	1248-9204 ; 1265-4906
ISSN (online)	1248-9204
ISSN	1265-4906
DOI	10.1007/s10029-018-1757-5
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