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  1. Book ; Online: Mapping of TB treatment providers at selected sites in Andhra Pradesh State, India / G. N. V. Ramana, B. M. Chandra Sekhar Naidu, K. J. R. Murthy

    Ramana, G. N. V / Chandra Sekhar Naidur, B. M / Murthy, K. J. R / WHO Global Tuberculosis Programme

    1997  

    Abstract: WHO/TB/97.233 ... 29 p. ... English ... ...

    Abstract WHO/TB/97.233

    29 p.

    English only
    Keywords Tuberculosis ; Pulmonary ; Health facilities ; Private sector ; Private practice ; Cost of illness ; Health care surveys ; Patient satisfaction ; India ; Communicable Diseases and their Control ; therapy ; utilization
    Language English
    Publisher Geneva : World Health Organization
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: Mapping of TB treatment providers at selected sites in Andhra Pradesh State, India / G. N. V. Ramana, B. M. Chandra Sekhar Naidu, K. J. R. Murthy

    Ramana, G. N. V / Chandra Sekhar Naidur, B. M / Murthy, K. J. R / WHO Global Tuberculosis Programme

    1997  

    Abstract: WHO/TB/97.233 ... 29 p. ...

    Abstract WHO/TB/97.233

    29 p.
    Keywords Tuberculosis ; Pulmonary ; Health Facilities ; Private Sector ; Private Practice ; Cost of Illness ; Health Care Surveys ; Patient Satisfaction ; India ; Communicable Diseases and their Control ; therapy ; utilization
    Language English
    Publisher World Health Organization
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Myasthenia Gravis: Do the Subtypes Matter?

    Murthy, J M K

    Annals of Indian Academy of Neurology

    2020  Volume 23, Issue 1, Page(s) 2

    Language English
    Publishing date 2020-01-21
    Publishing country India
    Document type Editorial
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_595_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Autosomal Dominant Spinocerebellar Ataxias: The Subtypes.

    Murthy, J M K

    Neurology India

    2020  Volume 68, Issue 1, Page(s) 92–93

    MeSH term(s) Arthrogryposis ; Humans ; India ; Spinocerebellar Ataxias/genetics ; Trinucleotide Repeats
    Language English
    Publishing date 2020-03-03
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.279663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Tuberculous Meningitis - Adjunctive Therapy: Corticosteroids, Aspirin, or Both.

    Murthy, J M K

    Neurology India

    2019  Volume 67, Issue 4, Page(s) 1003–1005

    MeSH term(s) Adrenal Cortex Hormones ; Antitubercular Agents ; Aspirin ; Combined Modality Therapy ; Humans ; Tuberculosis, Meningeal
    Chemical Substances Adrenal Cortex Hormones ; Antitubercular Agents ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2019-06-19
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.266280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Guillian-Barre syndrome and variants: Antiganglioside antibodies.

    Murthy, J M K

    Neurology India

    2017  Volume 65, Issue 5, Page(s) 971–972

    MeSH term(s) Antibodies/immunology ; Guillain-Barre Syndrome/immunology ; Humans
    Chemical Substances Antibodies
    Language English
    Publishing date 2017-10-04
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/neuroindia.NI_738_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Diagnostic value of proximal cutaneous nerve biopsy in brachial and lumbosacral plexus pathologies.

    Wu, Kitty Y / Murthy, Nikhil K / Howe, Benjamin M / Dyck, P James B / Spinner, Robert J

    Acta neurochirurgica

    2023  Volume 165, Issue 5, Page(s) 1189–1194

    Abstract: Background: Brachial and lumbosacral plexopathies can result from numerous non-traumatic etiologies, including those of inflammatory, autoimmune, or neoplastic origin, that often require nerve biopsy for diagnosis. The purpose of this study was to ... ...

    Abstract Background: Brachial and lumbosacral plexopathies can result from numerous non-traumatic etiologies, including those of inflammatory, autoimmune, or neoplastic origin, that often require nerve biopsy for diagnosis. The purpose of this study was to evaluate the diagnostic efficacy of medial antebrachial cutaneous nerve (MABC) and posterior femoral cutaneous nerve (PFCN) nerve biopsies in proximal brachial and lumbosacral plexus pathology.
    Method: Patients undergoing MABC or PFCN nerve biopsies at a single institution were reviewed. Patient demographics, clinical diagnosis, symptom duration, intraoperative findings, post-operative complications, and pathology results were recorded. Biopsy results were classified as diagnostic, inconclusive, or negative based on the final pathology.
    Results: Thirty patients undergoing MABC biopsies in the proximal arm or axilla and five patients with PFCN biopsies in the thigh or buttock were included. MABC biopsies were diagnostic in 70% of cases overall and 85% diagnostic in cases where pre-operative MRI also demonstrated abnormalities in the MABC. PFCN biopsies were diagnostic in 60% of cases overall and in 100% of patients with abnormal pre-operative MRIs. There were no biopsy-related post-operative complications in either group.
    Conclusions: In diagnosing non-traumatic etiologies of brachial and lumbosacral plexopathies, proximal biopsies of the MABC and PFCN provide high diagnostic value with low donor morbidity.
    MeSH term(s) Humans ; Brachial Plexus ; Lumbosacral Plexus ; Skin/innervation ; Buttocks ; Biopsy/adverse effects ; Brachial Plexus Neuropathies/diagnosis ; Brachial Plexus Neuropathies/etiology ; Brachial Plexus Neuropathies/surgery
    Language English
    Publishing date 2023-04-03
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05565-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Study of Variations of the Stomach in Adults and Growth of the Fetal Stomach.

    Karnul, Azra M / Murthy, Chaitanya K

    Cureus

    2022  Volume 14, Issue 8, Page(s) e28517

    Abstract: ... axis) in 14%. Type III classification comprised the variations in shape, with a J-shaped stomach in 58 ...

    Abstract The stomach is a site for various pathological conditions like congestive hypertrophic pyloric stenosis, peptic ulcer, gastroesophageal reflux disease (GERD), and carcinoma of the stomach. Further, for the treatment of obesity too, surgical manipulation of the stomach is done by a bariatric surgeon. With the availability of a wide range of diagnostic tools like barium meals, USG, CT scan, MRI, and endoscopy, it is possible to identify the variations in the position and shape of the stomach and developmental defects while diagnosing diseases. As thorough knowledge of stomach position and variations will help in preoperative planning and preventing inadvertent damage during surgeries, this topic was taken up for research. Aims and objectives This study aims to study the variations of the stomach in human cadavers and dead fetuses with regard to its length, shape, capacity, ends, curvatures, and mucosal folding and classify them into various groups. In addition, this study also aims to assess the pattern of growth of the stomach in fetuses. Material and methods The stomachs of 50 adult cadavers and 20 dead fetuses were studied by standard dissection method, concerning their topography, shape, level of the cardiac and pyloric orifice, cardiac angle, length of greater (GC) and lesser curvatures (LC), pyloric sphincter, volume, and mucosal folds. Results The stomach was located in the left hypochondriac quadrant in 78% of the samples and in relation to the 7th costal cartilage in 64%. The two main types of classification established were Type I (variation in position along the vertical axis) in 4% and Type II (variation in position along the transverse axis) in 14%. Type III classification comprised the variations in shape, with a J-shaped stomach in 58%, cylindrical in 20%, crescentic in 14%, and reversed L in 8%. The average length showed significant differences in males, 19±2.48 cm vis-a-vis females, 17.1±2.01 cm. In 66% of the cases, the cardiac orifice was to the left of the midline behind the 7th costal cartilage, and the pyloric orifice was to the right, 1.2 cm to the midline and in the transpyloric plane in 76%. The average GC and LC were 33.6±1.43 cm and 27±5.28 cm, respectively. GC was more significant in males. The average length and diameter of the pyloric canal were about 3.56±0.38 cm & 0.77±0.23 cm, respectively. The thickness of the pyloric sphincter did not show a significant gender difference. The average volume was 289.88±69.15 ml. Rugae were normally spaced in 68%, nearly spaced in 18%, and widely spaced in 6%. The fetal stomach measurements were significantly correlated to gestational age and showed linear growth. Conclusion The study of the morphology of the stomach and its variations are important not only to surgeons and anatomists but also to gastroenterologists. The linear growth of the stomach in embryos helps radiologists and obstetricians to diagnose intrauterine growth retardation (IUGR) and congenital anomalies early.
    Language English
    Publishing date 2022-08-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.28517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: New-onset focal epilepsy in adults: Antiepileptic drug treatment.

    Murthy, J M K

    Neurology India

    2017  Volume 65, Issue Supplement, Page(s) S78–S82

    Abstract: Focal epilepsy, non-syndromic, is by far the most prevalent epilepsy in adults. Antiepileptic drug (AED) prescription in patients with new-onset focal epilepsy is often challenging. The factors that determine AED of choice depends both on the patient- ... ...

    Abstract Focal epilepsy, non-syndromic, is by far the most prevalent epilepsy in adults. Antiepileptic drug (AED) prescription in patients with new-onset focal epilepsy is often challenging. The factors that determine AED of choice depends both on the patient-specific and AED-specific variables. Monotherapy should the initial strategy. Failure to monotherapy can be due to lack of efficacy, severe adverse events, or a hypersensitivity reaction. In such patients, the next strategy should be alternate monotherapy trials. In patients who fail up to three monotherapy trials, duotherapy with drugs having different primary mechanisms of action should be the next step. Multiple duotherapy should be tried before considering adding polytherapy. In spite of such pragmatic strategies, about 25% of patients may never become seizure free for any complete year throughout follow-up. Patients in this group should be evaluated for non-pharmacological treatment options, particularly epilepsy surgery.
    MeSH term(s) Adult ; Anticonvulsants/therapeutic use ; Carbamazepine/therapeutic use ; Drug Therapy, Combination ; Epilepsies, Partial/drug therapy ; Epilepsy/drug therapy ; Female ; Humans ; Male ; Recurrence
    Chemical Substances Anticonvulsants ; Carbamazepine (33CM23913M)
    Language English
    Publishing date 2017-03-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/neuroindia.NI_69_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: PET imaging characteristics of neuromuscular choristoma and associated desmoid-type fibromatosis.

    Marek, Tomas / Spinner, Robert J / Carter, Jodi M / Murthy, Nikhil K / Amrami, Kimberly K / Broski, Stephen M

    Acta neurochirurgica

    2023  Volume 165, Issue 5, Page(s) 1171–1177

    Abstract: Background: Neuromuscular choristoma (NMC) is a rare peripheral nerve lesion characterized by abnormal presence of muscle within nerve. Associated desmoid-type fibromatosis (NMC-DTF) often develops. We report : Methods: Our institutional database was ...

    Abstract Background: Neuromuscular choristoma (NMC) is a rare peripheral nerve lesion characterized by abnormal presence of muscle within nerve. Associated desmoid-type fibromatosis (NMC-DTF) often develops. We report
    Methods: Our institutional database was searched for all NMC cases. Inclusion criteria were 1) confirmed diagnosis of NMC with or without biopsy, and 2) available PET and MRI studies. PET data included SUVmax and SUVmean of NMCs, contralateral limb normal skeletal muscle and unaffected nerves, and SUVmax of NMC-DTF if present. SUV values were compared using paired t-test. A p value of < 0.05 was considered statistically significant.
    Results: Our cohort consisted of 9 patients with NMC, 8 cases involving sciatic nerve and 1 of brachial plexus. On PET imaging, all NMC-affected nerve segments showed significantly higher FDG uptake (SUVmax/mean) compared to both contralateral normal nerve and normal skeletal muscle (all P < 0.05). Similar to sporadic DTF, NMC-DTF was highly FDG-avid (average SUVmax of 4.2). SUVmax in NMC with or without concurrent NMC-DTF did not differ (p = 0.76). Within NMC-affected nerve segment, FDG activity was relatively higher in areas with low T1/T2 MR signal.
    Conclusion: All NMCs were more FDG avid compared to both normal skeletal muscle and contralateral unaffected nerve, arguing against the presence of heterotopic muscle in NMC as the source of FDG avidity. FDG avidity within NMC may reflect subclinical NMC-DTF or a precursor lesion, as NMC-DTF are highly FDG-avid, and the highest regions of FDG avidity in NMC occurred in regions with MR characteristics associated with NMC-DTF (i.e., lower T1/T2 signal). We believe that the integration of FDG PET with serial MR imaging in patient follow up will clarify its utility in both detection and surveillance of NMC-DTF.
    MeSH term(s) Humans ; Fibromatosis, Aggressive/pathology ; Fluorodeoxyglucose F18 ; Choristoma/pathology ; Positron-Emission Tomography ; Hamartoma ; Magnetic Resonance Imaging/methods ; Muscle, Skeletal/pathology ; Sciatic Nerve/pathology ; Radiopharmaceuticals ; Retrospective Studies
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Radiopharmaceuticals
    Language English
    Publishing date 2023-03-14
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05547-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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