LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 305

Search options

  1. Article ; Online: The history of endoscopic ultrasound-guided fine-needle aspiration: development and progress.

    Kanno, Atsushi / Ikeda, Eriko / Ando, Kozue / Yokoyama, Kensuke / Yamamoto, Hironori

    Journal of medical ultrasonics (2001)

    2024  

    Abstract: Endoscopic ultrasonography (EUS) is an important diagnostic technique to accurately diagnose diseases originating from organs near the gastrointestinal tract. EUS-guided fine-needle aspiration (FNA) has improved the histopathological diagnosis. EUS-FNA ... ...

    Abstract Endoscopic ultrasonography (EUS) is an important diagnostic technique to accurately diagnose diseases originating from organs near the gastrointestinal tract. EUS-guided fine-needle aspiration (FNA) has improved the histopathological diagnosis. EUS-FNA has been further developed over a long period of 40 years. The history of the development of endosonographic scopes, ultrasonographic observation systems, puncture needles, and puncture methods will provide a springboard for future development.
    Language English
    Publishing date 2024-01-20
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 1396630-3
    ISSN 1613-2254 ; 0287-0592 ; 1346-4523
    ISSN (online) 1613-2254
    ISSN 0287-0592 ; 1346-4523
    DOI 10.1007/s10396-023-01400-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2695: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.B 2695 -Engl.Ausg.-: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: A convenient fluorimetry-based degranulation assay using RBL-2H3 cells.

    Higashio, Hironori / Yokoyama, Takuya / Saino, Tomoyuki

    Bioscience, biotechnology, and biochemistry

    2023  Volume 88, Issue 2, Page(s) 181–188

    Abstract: Type I hypersensitivity is triggered by mast cell degranulation, a stimulus-induced exocytosis of preformed secretory granules (SGs) containing various inflammatory mediators. The degree of degranulation is generally expressed as a percentage of ... ...

    Abstract Type I hypersensitivity is triggered by mast cell degranulation, a stimulus-induced exocytosis of preformed secretory granules (SGs) containing various inflammatory mediators. The degree of degranulation is generally expressed as a percentage of secretory granule markers (such as β-hexosaminidase and histamine) released into the external solution, and considerable time and labor are required for the quantification of markers in both the supernatants and cell lysates. In this study, we developed a simple fluorimetry-based degranulation assay using rat basophilic leukemia (RBL-2H3) mast cells. During degranulation, the styryl dye FM1-43 in the external solution fluorescently labeled the newly exocytosed SGs, whose increase in intensity was successively measured using a fluorescence microplate reader. In addition to the rate of β-hexosaminidase secretion, the cellular FM1-43 intensity successfully represented the degree and kinetics of degranulation under various conditions, suggesting that this method facilitates multi-sample and/or multi-time-point analyses required for screening substances regulating mast cell degranulation.
    MeSH term(s) Rats ; Animals ; Cell Degranulation ; Pyridinium Compounds ; Secretory Vesicles/metabolism ; Mast Cells ; beta-N-Acetylhexosaminidases ; Quaternary Ammonium Compounds
    Chemical Substances FM1 43 ; Pyridinium Compounds ; beta-N-Acetylhexosaminidases (EC 3.2.1.52) ; Quaternary Ammonium Compounds
    Language English
    Publishing date 2023-11-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1093/bbb/zbad160
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4647: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Strong evolutionary constraints against amino acid changes in the P2 subdomain of sapovirus GI.1 capsid protein VP1.

    Yokoyama, Masaru / Doan, Yen Hai / Motomura, Kazushi / Sato, Hironori / Oka, Tomoichiro

    Biochemical and biophysical research communications

    2024  Volume 710, Page(s) 149878

    Abstract: Sapovirus (SaV) is a nonenveloped RNA virus that causes acute gastroenteritis in humans. Although SaV is a clinically important pathogen in children, an effective vaccine is currently unavailable. The capsid protein VP1 of SaVs forms the outer shell of ... ...

    Abstract Sapovirus (SaV) is a nonenveloped RNA virus that causes acute gastroenteritis in humans. Although SaV is a clinically important pathogen in children, an effective vaccine is currently unavailable. The capsid protein VP1 of SaVs forms the outer shell of the virion and is highly diverse, as often seen in the virion-surface proteins of RNA viruses, creating an obstacle for vaccine development. We here report a unique phenomenon pertaining to the variation of SaV VP1. Phylogenetic and information entropy analyses using full-length VP1 sequences from a public database consistently showed that the amino acid sequences of the VP1 protein have been highly conserved over more than 40 years in the major epidemic genotype GI.1 but not in GI.2. Structural modeling showed that even the VP1 P2 subdomain, which is arranged on the outermost shell of the virion and presumably exposed to anti-SaV antibodies, remained highly homogeneous in GI.1 but not in GI.2. These results suggest strong evolutionary constraints against amino acid changes in the P2 subdomain of the SaV GI.1 capsid and illustrate a hitherto unappreciated mechanism, i.e., preservation of the VP1 P2 subdomain, involved in SaV survival. Our findings could have important implications for the development of an anti-SaV vaccine.
    MeSH term(s) Child ; Humans ; Sapovirus/genetics ; Capsid Proteins/genetics ; Phylogeny ; Amino Acids/genetics ; Vaccines ; Genotype ; Feces
    Chemical Substances Capsid Proteins ; Amino Acids ; Vaccines
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2024.149878
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli.

    Li, Pengcheng / Yokoyama, Mio / Okamoto, Daiki / Nakatani, Hironori / Yagi, Tohru

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 17175

    Abstract: Subthreshold depressive (sD) states and major depression are considered to occur on a continuum, and there are only quantitative and not qualitative differences between depressive states in healthy individuals and patients with depression. sD is showing ... ...

    Abstract Subthreshold depressive (sD) states and major depression are considered to occur on a continuum, and there are only quantitative and not qualitative differences between depressive states in healthy individuals and patients with depression. sD is showing a progressively increasing prevalence and has a lifelong impact, and the social and clinical impacts of sD are no less than those of major depressive disorder (MDD). Because depression leads to biased cognition, patients with depression and healthy individuals show different visual processing properties. However, it remains unclear whether there are significant differences in visual information recognition among healthy individuals with various depressive states. In this study, we investigated the event-related potentials (ERPs) and event-related spectrum perturbation (ERSP) of healthy individuals with various depressive states during the perception of emotional visual stimulation. We show that different neural activities can be detected even among healthy individuals. We divided healthy participants into high, middle, and low depressive state groups and found that participants in a high depressive state had a lower P300 amplitude and significant differences in fast and slow neural responses in the frontal and parietal lobes. We anticipate our study to provide useful parameters for assessing the evaluation of depressive states in healthy individuals.
    MeSH term(s) Humans ; Depressive Disorder, Major/psychology ; Healthy Volunteers ; Emotions/physiology ; Evoked Potentials ; Cognition
    Language English
    Publishing date 2023-10-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44368-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Investigations on Adsorption of Inorganic Ions in Aqueous Solution to Some Metal Oxides, Hydroxides and a Carbonate by the X-Ray Spectroscopic Method.

    Ohashi, Hironori / Yonezu, Kotaro / Kawamoto, Daisuke / Yokoyama, Takushi

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    2021  Volume 37, Issue 10, Page(s) 1321–1330

    Abstract: Why does the adsorption and concentration of inorganic chemical species proceed at aqueous-solid interfaces? In this review paper, we discuss the use of X-ray chemical state analysis to elucidate the intrinsic adsorption mechanism. Based on the chemical ... ...

    Abstract Why does the adsorption and concentration of inorganic chemical species proceed at aqueous-solid interfaces? In this review paper, we discuss the use of X-ray chemical state analysis to elucidate the intrinsic adsorption mechanism. Based on the chemical states of the species adsorbed to solids as determined by X-ray chemical state analysis, possible adsorption mechanisms are discussed. The driving forces of adsorption are represented by the Gibbs free energy change (ΔG
    Language English
    Publishing date 2021-09-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1483376-1
    ISSN 1348-2246 ; 1348-2246
    ISSN (online) 1348-2246
    ISSN 1348-2246
    DOI 10.2116/analsci.20SAR20
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Sensitivity of a bone-equivalent polymer gel dosimeter for measuring the dose to bone during radiation therapy.

    Kumahara, Narumi / Takemura, Akihiro / Ishihara, Shouta / Noto, Kimiya / Kojima, Hironori / Isomura, Naoki / Yokoyama, Haruna / Goto, Itsuki

    Radiological physics and technology

    2023  Volume 16, Issue 2, Page(s) 227–234

    Abstract: Treatment planning systems that use the Monte Carlo algorithm can calculate the dose to the medium ( ... ...

    Abstract Treatment planning systems that use the Monte Carlo algorithm can calculate the dose to the medium (D
    MeSH term(s) Radiation Dosimeters ; Algorithms ; Japan ; Monte Carlo Method ; Polymers ; Radiometry ; Gels
    Chemical Substances Polymers ; Gels
    Language English
    Publishing date 2023-03-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2433581-2
    ISSN 1865-0341 ; 1865-0333
    ISSN (online) 1865-0341
    ISSN 1865-0333
    DOI 10.1007/s12194-023-00710-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Pancreatitis and cholangitis caused by metallic wire in the duodenal submucosa and muscularis near the papilla: removal by endoscopic submucosal dissection using the pocket-creation method.

    Ando, Kozue / Kanno, Atsushi / Ino, Yuji / Fukuda, Hisashi / Ikeda, Eriko / Yokoyama, Kensuke / Lefor, Alan Kawarai / Yamamoto, Hironori

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2023  Volume 8, Issue 9, Page(s) 370–373

    Abstract: Video 1A metalic wire removed by endoscopic submucosal dissection using the pocket-creation method. ...

    Abstract Video 1A metalic wire removed by endoscopic submucosal dissection using the pocket-creation method.
    Language English
    Publishing date 2023-08-02
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2023.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Cis

    Masuda, Takao / Kotani, Osamu / Yokoyama, Masaru / Abe, Yuya / Kawai, Gota / Sato, Hironori

    Viruses

    2022  Volume 15, Issue 1

    Abstract: Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in ... ...

    Abstract Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the
    MeSH term(s) Allosteric Regulation ; HIV Reverse Transcriptase/genetics ; HIV Reverse Transcriptase/metabolism ; Reverse Transcriptase Inhibitors/pharmacology ; HIV Integrase/metabolism
    Chemical Substances reverse transcriptase, Human immunodeficiency virus 1 (EC 2.7.7.-) ; HIV Reverse Transcriptase (EC 2.7.7.49) ; Reverse Transcriptase Inhibitors ; HIV Integrase (EC 2.7.7.-)
    Language English
    Publishing date 2022-12-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15010031
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Environmental pH signals the release of monosaccharides from cell wall in coral symbiotic alga.

    Ishii, Yuu / Ishii, Hironori / Kuroha, Takeshi / Yokoyama, Ryusuke / Deguchi, Ryusaku / Nishitani, Kazuhiko / Minagawa, Jun / Kawata, Masakado / Takahashi, Shunichi / Maruyama, Shinichiro

    eLife

    2023  Volume 12

    Abstract: Reef-building corals thrive in oligotrophic environments due to their possession of endosymbiotic algae. Confined to the low pH interior of the symbiosome within the cell, the algal symbiont provides the coral host with photosynthetically fixed carbon. ... ...

    Abstract Reef-building corals thrive in oligotrophic environments due to their possession of endosymbiotic algae. Confined to the low pH interior of the symbiosome within the cell, the algal symbiont provides the coral host with photosynthetically fixed carbon. However, it remains unknown how carbon is released from the algal symbiont for uptake by the host. Here we show, using cultured symbiotic dinoflagellate,
    MeSH term(s) Animals ; Monosaccharides ; Anthozoa ; Ecosystem ; Carbon ; Cell Wall ; Dinoflagellida/genetics ; Cellulases ; Hydrogen-Ion Concentration
    Chemical Substances Monosaccharides ; Carbon (7440-44-0) ; Cellulases (EC 3.2.1.-)
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.80628
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: A simple method to reposition a dislocated lumen-apposing metal stent during endoscopic necrosectomy.

    Yokoyama, Kensuke / Kanno, Atsushi / Ushio, Jun / Tamada, Kiichi / Yamamoto, Hironori

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2020  Volume 6, Issue 1, Page(s) 32–34

    Language English
    Publishing date 2020-10-24
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2020.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top