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  1. Article: Role of Hypnosis in Dental Treatment: A Narrative Review.

    Venkiteswaran, Annapurny / Tandon, Shobha

    Journal of International Society of Preventive & Community Dentistry

    2021  Volume 11, Issue 2, Page(s) 115–124

    Abstract: ... dental treatment. The PICO used to answer the objectives are (P) dental patients, (I) hypnosis, (C ... conventional behaviour management techniques & (O) reduced pain/anxiety.: Materials and methods ...

    Abstract Aim: This narrative aims to outline the use of hypnosis in managing dental anxiety in during dental treatment. The PICO used to answer the objectives are (P) dental patients, (I) hypnosis, (C) conventional behaviour management techniques & (O) reduced pain/anxiety.
    Materials and methods: An electronic search of three databases; PubMed, Scopus and EBSCOhost was conducted using the keywords "hypnosis or hypnotherapy" AND "dentistry or dental" between the year 2000 and 2020. A total of 19 studies were selected based on eligibility. Data extracted were study subject, design of study, parameters used to assess, type of hypnosis script used and the study outcome.
    Results: The studies show that hypnosis is effective in pain management and dental anxiety. It can also be used for improving compliance in patients who are wearing orthodontic appliances (Trakyali
    Conclusion: Hypnosis has the potential to be a useful tool in the management of children and adults.
    Language English
    Publishing date 2021-04-15
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2734043-0
    ISSN 2250-1002 ; 2231-0762
    ISSN (online) 2250-1002
    ISSN 2231-0762
    DOI 10.4103/jispcd.JISPCD_320_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The COVID-19 Pandemic Significantly Impacts Pregnancy Planning and Mental Health of Women With Inflammatory Bowel Disease.

    Tandon, Parul / O'Connor, Katie / Nguyen, Geoffrey / Maxwell, Cynthia / Huang, Vivian

    Journal of clinical gastroenterology

    2023  Volume 57, Issue 2, Page(s) 178–184

    Abstract: Background and goals: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted daily life, particularly in those with inflammatory bowel disease (IBD). We aimed to determine the impact of the pandemic on the pregnancy planning and ... ...

    Abstract Background and goals: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted daily life, particularly in those with inflammatory bowel disease (IBD). We aimed to determine the impact of the pandemic on the pregnancy planning and mental health of women with IBD.
    Methods: Women with IBD (age 18 to 45 y) were asked to complete anonymous surveys on the impact of the COVID-19 pandemic on pregnancy planning and mental health symptoms such as stress (Perceived Stress Scale), depression (Patient Health Questionnaire-9), and anxiety (Generalized Anxiety Disorder-7). Univariate and multivariable analyses were conducted to identify risk factors associated with stress, depression, and anxiety during the pandemic.
    Results: Seventy-three women with IBD were included (mean age: 32.1). Of 39 patients who were preconception, 20 (51.3%) reported a significant impact of the pandemic on pregnancy planning, with common reasons for not planning conception being fear of transmission of the virus to the fetus, lack of social supports, and no desire to be in hospital during pregnancy. Over half of all women reported an increase in stress and depression symptoms during the pandemic, with over half also reporting symptoms of anxiety. On multivariable linear regression analyses, increased anxiety levels were a significant predictor of increased stress and depression symptoms during the pandemic. Urban residence and younger age were significant predictors of increased anxiety symptoms during the pandemic.
    Conclusion: A significant proportion of women with IBD experienced an impact of the COVID-19 pandemic on pregnancy planning and mental health illnesses such as stress, depression, and anxiety.
    MeSH term(s) Pregnancy ; Humans ; Female ; Adult ; Adolescent ; Young Adult ; Middle Aged ; COVID-19/epidemiology ; Mental Health ; Pandemics ; SARS-CoV-2 ; Depression/epidemiology ; Stress, Psychological/epidemiology ; Stress, Psychological/diagnosis ; Anxiety/epidemiology ; Anxiety/etiology
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 448460-5
    ISSN 1539-2031 ; 0192-0790
    ISSN (online) 1539-2031
    ISSN 0192-0790
    DOI 10.1097/MCG.0000000000001672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Extent of Resection Thresholds in Molecular Subgroups of Newly Diagnosed Isocitrate Dehydrogenase-Wildtype Glioblastoma.

    Dono, Antonio / Zhu, Ping / Takayasu, Takeshi / Arevalo, Octavio / Riascos, Roy / Tandon, Nitin / Ballester, Leomar Y / Esquenazi, Yoshua

    Neurosurgery

    2024  

    Abstract: ... prolonged overall survival (OS) in multivariable analysis (hazard ratio: 0.56, P = .030). Patients ... with EOR>89% (10.5 vs 18.8 months; HR: 2.78, P = .013); however, EOR/RTV was not associated with OS ... had significantly worse OS than PTEN-wildtype (9.5 vs 15.4 months; HR: 4.53, P < .001).: Conclusion ...

    Abstract Background and objectives: Maximizing the extent of resection (EOR) improves outcomes in glioblastoma (GBM). However, previous GBM studies have not addressed the EOR impact in molecular subgroups beyond IDH1/IDH2 status. In the current article, we evaluate whether EOR confers a benefit in all GBM subtypes or only in particular molecular subgroups.
    Methods: A retrospective cohort of newly diagnosed GBM isocitrate dehydrogenase (IDH)-wildtype undergoing resection were prospectively included in a database (n = 138). EOR and residual tumor volume (RTV) were quantified with semiautomated software. Formalin-fixed paraffin-embedded tumor tissues were analyzed by targeted next-generation sequencing. The association between recurrent genomic alterations and EOR/RTV was evaluated using a recursive partitioning analysis to identify thresholds of EOR or RTV that may predict survival. The Kaplan-Meier methods and multivariable Cox proportional hazards regression methods were applied for survival analysis.
    Results: Patients with EOR ≥88% experienced 44% prolonged overall survival (OS) in multivariable analysis (hazard ratio: 0.56, P = .030). Patients with alterations in the TP53 pathway and EOR <89% showed reduced OS compared to TP53 pathway altered patients with EOR>89% (10.5 vs 18.8 months; HR: 2.78, P = .013); however, EOR/RTV was not associated with OS in patients without alterations in the TP53 pathway. Meanwhile, in all patients with EOR <88%, PTEN-altered had significantly worse OS than PTEN-wildtype (9.5 vs 15.4 months; HR: 4.53, P < .001).
    Conclusion: Our results suggest that a subset of molecularly defined GBM IDH-wildtype may benefit more from aggressive resections. Re-resections to optimize EOR might be beneficial in a subset of molecularly defined GBMs. Molecular alterations should be taken into consideration for surgical treatment decisions in GBM IDH-wildtype.
    Language English
    Publishing date 2024-04-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000002964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: One Health WASH

    Jiménez, C.E.P. / Keestra, S.M. / Tandon, P. / Pickering, A.J. / Moodley, Arshnee / Cumming, O. / Chandler, C.I.R.

    BMJ Global Health

    an AMR-smart integrative approach to preventing and controlling infection in farming communities

    2023  

    Abstract: While the One Health framework is now widely accepted as a strength in understanding antimicrobial resistance (AMR), its application in intervention design to prevent and control drug-resistant infections across humans, animals, and the environment ... ...

    Abstract While the One Health framework is now widely accepted as a strength in understanding antimicrobial resistance (AMR), its application in intervention design to prevent and control drug-resistant infections across humans, animals, and the environment remains weak. The potential for infection prevention and control measures to contribute to the AMR agenda is recognised in rhetoric, but evidence to guide action is patchy and uncoordinated. While water, sanitation, and hygiene (WASH) and on-farm biosecurity interventions are key strategies for preventing and controlling infections, they are frequently implemented separately for humans and animals. We argue for integration across these sectors to improve planning for AMR control.
    Keywords antimicrobial resistance ; one health approach ; agriculture ; water ; hygiene
    Language English
    Publishing date 2023-03-08T09:53:19Z
    Publisher BMJ
    Publishing country fr
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: CONTIGUOUS RELATIONS FOR THE H-FUNCTION OF n VARIABLES

    O. P. TANDON

    Proceedings of Indian National Science Academy, Vol 11, Iss

    2015  Volume 3

    Abstract: CONTIGUOUS RELATIONS FOR THE H-FUNCTION OF n ... ...

    Abstract CONTIGUOUS RELATIONS FOR THE H-FUNCTION OF n VARIABLES
    Keywords Science ; Q
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Indian National Science Academy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Biosecurity and water, sanitation, and hygiene (WASH) interventions in animal agricultural settings for reducing infection burden, antibiotic use, and antibiotic resistance

    Jiménez, C.E.P. / Keestra, S. / Tandon, P. / Cumming, O. / Pickering, A.J. / Moodley, Arshnee / Chandler, C.I.R.

    Lancet Planetary Health

    a One Health systematic review

    2023  

    Abstract: Prevention and control of infections across the One Health spectrum is essential for improving antibiotic use and addressing the emergence and spread of antibiotic resistance. Evidence for how best to manage these risks in agricultural communities—45% of ...

    Abstract Prevention and control of infections across the One Health spectrum is essential for improving antibiotic use and addressing the emergence and spread of antibiotic resistance. Evidence for how best to manage these risks in agricultural communities—45% of households globally—has not been systematically assembled. This systematic review identifies and summarises evidence from on-farm biosecurity and water, sanitation, and hygiene (WASH) interventions with the potential to directly or indirectly reduce infections and antibiotic resistance in animal agricultural settings. We searched 17 scientific databases (including Web of Science, PubMed, and regional databases) and grey literature from database inception to Dec 31, 2019 for articles that assessed biosecurity or WASH interventions measuring our outcomes of interest; namely, infection burden, microbial loads, antibiotic use, and antibiotic resistance in animals, humans, or the environment. Risk of bias was assessed with the Systematic Review Centre for Laboratory Animal Experimentation tool, Risk of Bias in Non-Randomized Studies of Interventions, and the Appraisal tool for Cross-Sectional Studies, although no studies were excluded as a result. Due to the heterogeneity of interventions found, we conducted a narrative synthesis. The protocol was pre-registered with PROSPERO (CRD42020162345). Of the 20 672 publications screened, 104 were included in this systematic review. 64 studies were conducted in high-income countries, 24 studies in upper-middle-income countries, 13 studies in lower-middle-income countries, two in low-income countries, and one included both upper-middle-income countries and lower-middle-income countries. 48 interventions focused on livestock (mainly pigs), 43 poultry (mainly chickens), one on livestock and poultry, and 12 on aquaculture farms. 68 of 104 interventions took place on intensive farms, 22 in experimental settings, and ten in smallholder or subsistence farms. Positive outcomes were reported for ten of 23 water studies, 17 of 35 ...
    Keywords antimicrobial resistance ; one health approach ; biosecurity ; water ; hygiene
    Language English
    Publishing date 2023-05-12T18:50:39Z
    Publisher Elsevier
    Publishing country fr
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Optimizing maternal and neonatal outcomes through tight control management of inflammatory bowel disease during pregnancy: a pilot feasibility study.

    Jogendran, Rohit / O'Connor, Katie / Jeyakumar, Ajani / Tandon, Parul / Nguyen, Geoffrey C / Maxwell, Cynthia / Huang, Vivian

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 8291

    Abstract: A home point-of care FCP test (IBDoc) and a self-reported clinical disease activity program (IBD Dashboard) may improve routine monitoring of IBD activity during pregnancy. We aimed to evaluate the feasibility of tight control management using remote ... ...

    Abstract A home point-of care FCP test (IBDoc) and a self-reported clinical disease activity program (IBD Dashboard) may improve routine monitoring of IBD activity during pregnancy. We aimed to evaluate the feasibility of tight control management using remote monitoring in pregnant patients with IBD. Pregnant patients (< 20 weeks) with IBD were prospectively enrolled from Mount Sinai Hospital between 2019 and 2020. Patients completed the IBDoc and IBD Dashboard at three core time points. Disease activity was measured clinically using the Harvey-Bradshaw Index (mHBI) for CD and partial Mayo (pMayo) for UC, or objectively using FCP. A feasibility questionnaire was completed in the third trimester. Seventy-seven percent of patients (24 of 31) completed the IBDoc and IBD Dashboard at all core time points. Twenty-four patients completed the feasibility questionnaires. All survey respondents strongly preferred using the IBDoc over standard lab-based testing and would use the home kit in the future. Exploratory analysis identified discordance rates of more than 50% between clinical and objective disease activity. Tight control management using remote monitoring may be feasible among pregnant patients with IBD. A combination of both clinical scores and objective disease markers may better predict disease activity.
    MeSH term(s) Pregnancy ; Female ; Infant, Newborn ; Humans ; Feasibility Studies ; Prospective Studies ; Inflammatory Bowel Diseases/diagnosis ; Inflammatory Bowel Diseases/therapy ; Surveys and Questionnaires ; Self Report ; Colitis, Ulcerative
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35332-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Perceptions and Prevalence of Cannabis Use in Women With Inflammatory Bowel Disease of Reproductive Age: A Cross-Sectional Study.

    Hossein-Javaheri, Nariman / O'Connor, Katie / Steinhart, Hillary / Deshpande, Amol / Maxwell, Cynthia / Huang, Vivian / Tandon, Parul

    Journal of the Canadian Association of Gastroenterology

    2023  Volume 7, Issue 2, Page(s) 204–211

    Abstract: Background: Many patients with inflammatory bowel disease (IBD) may use cannabis for relief of symptoms. During pregnancy, however, cannabis exposure may be associated with adverse pregnancy outcomes. We aimed to determine the prevalence and perceptions ...

    Abstract Background: Many patients with inflammatory bowel disease (IBD) may use cannabis for relief of symptoms. During pregnancy, however, cannabis exposure may be associated with adverse pregnancy outcomes. We aimed to determine the prevalence and perceptions of cannabis use in women with IBD.
    Methods: Through recruitment at Mount Sinai Hospital and online platforms such as Twitter, women with IBD (age 18-45) were asked to complete anonymous surveys on demographics, cannabis use, perception of use during pregnancy, and discussing its use with healthcare providers (HCP). Categorical variables were reported as frequencies and compared across groups with the chi-square test.
    Results: One-hundred and two pregnant patients with IBD were included in this study, 19 (18.6%) reported using cannabis. Current users were more likely to report constant pain in the last 12 months and discuss its use with their HCP. Fifty-three (52.0%) women were unsure of the specific risks associated with cannabis use during pregnancy, and only 15 (14.7%) had ever discussed its use with their HCP. Those who had discussed cannabis use with their HCP were more likely to have prior IBD-related surgery, perceive its use unsafe during pregnancy, and be more likely to be using cannabis.
    Conclusion: Many women with IBD report uncertainty of the risks of cannabis use during pregnancy and the majority have never discussed cannabis use with their providers. With the increasing legalization of cannabis in many jurisdictions, it is imperative patients and healthcare providers discuss the risks and benefits of its use, particularly during vulnerable times such as pregnancy.
    Language English
    Publishing date 2023-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2940642-0
    ISSN 2515-2092 ; 2515-2084
    ISSN (online) 2515-2092
    ISSN 2515-2084
    DOI 10.1093/jcag/gwad049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: One Health WASH: an AMR-smart integrative approach to preventing and controlling infection in farming communities.

    Pinto Jimenez, Chris E / Keestra, Sarai M / Tandon, Pranav / Pickering, Amy J / Moodley, Arshnee / Cumming, Oliver / Chandler, Clare I R

    BMJ global health

    2023  Volume 8, Issue 3

    MeSH term(s) Humans ; One Health ; Agriculture
    Language English
    Publishing date 2023-03-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2022-011263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Biosecurity and water, sanitation, and hygiene (WASH) interventions in animal agricultural settings for reducing infection burden, antibiotic use, and antibiotic resistance: a One Health systematic review.

    Pinto Jimenez, Chris E / Keestra, Sarai / Tandon, Pranav / Cumming, Oliver / Pickering, Amy J / Moodley, Arshnee / Chandler, Clare I R

    The Lancet. Planetary health

    2023  Volume 7, Issue 5, Page(s) e418–e434

    Abstract: Prevention and control of infections across the One Health spectrum is essential for improving antibiotic use and addressing the emergence and spread of antibiotic resistance. Evidence for how best to manage these risks in agricultural communities-45% of ...

    Abstract Prevention and control of infections across the One Health spectrum is essential for improving antibiotic use and addressing the emergence and spread of antibiotic resistance. Evidence for how best to manage these risks in agricultural communities-45% of households globally-has not been systematically assembled. This systematic review identifies and summarises evidence from on-farm biosecurity and water, sanitation, and hygiene (WASH) interventions with the potential to directly or indirectly reduce infections and antibiotic resistance in animal agricultural settings. We searched 17 scientific databases (including Web of Science, PubMed, and regional databases) and grey literature from database inception to Dec 31, 2019 for articles that assessed biosecurity or WASH interventions measuring our outcomes of interest; namely, infection burden, microbial loads, antibiotic use, and antibiotic resistance in animals, humans, or the environment. Risk of bias was assessed with the Systematic Review Centre for Laboratory Animal Experimentation tool, Risk of Bias in Non-Randomized Studies of Interventions, and the Appraisal tool for Cross-Sectional Studies, although no studies were excluded as a result. Due to the heterogeneity of interventions found, we conducted a narrative synthesis. The protocol was pre-registered with PROSPERO (CRD42020162345). Of the 20 672 publications screened, 104 were included in this systematic review. 64 studies were conducted in high-income countries, 24 studies in upper-middle-income countries, 13 studies in lower-middle-income countries, two in low-income countries, and one included both upper-middle-income countries and lower-middle-income countries. 48 interventions focused on livestock (mainly pigs), 43 poultry (mainly chickens), one on livestock and poultry, and 12 on aquaculture farms. 68 of 104 interventions took place on intensive farms, 22 in experimental settings, and ten in smallholder or subsistence farms. Positive outcomes were reported for ten of 23 water studies, 17 of 35 hygiene studies, 15 of 24 sanitation studies, all three air-quality studies, and 11 of 17 other biosecurity-related interventions. In total, 18 of 26 studies reported reduced infection or diseases, 37 of 71 studies reported reduced microbial loads, four of five studies reported reduced antibiotic use, and seven of 20 studies reported reduced antibiotic resistance. Overall, risk of bias was high in 28 of 57 studies with positive interventions and 17 of 30 studies with negative or neutral interventions. Farm-management interventions successfully reduced antibiotic use by up to 57%. Manure-oriented interventions reduced antibiotic resistance genes or antibiotic-resistant bacteria in animal waste by up to 99%. This systematic review highlights the challenges of preventing and controlling infections and antimicrobial resistance, even in well resourced agricultural settings. Most of the evidence emerges from studies that focus on the farm itself, rather than targeting agricultural communities or the broader social, economic, and policy environment that could affect their outcomes. WASH and biosecurity interventions could complement each other when addressing antimicrobial resistance in the human, animal, and environmental interface.
    MeSH term(s) Animals ; Humans ; Swine ; Sanitation ; Biosecurity ; Water ; Cross-Sectional Studies ; One Health ; Chickens ; Hygiene ; Drug Resistance, Microbial ; Anti-Infective Agents
    Chemical Substances Water (059QF0KO0R) ; Anti-Infective Agents
    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 2542-5196
    ISSN (online) 2542-5196
    DOI 10.1016/S2542-5196(23)00049-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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