LIVIVO - Search results -

Search results

Result 1 - 10 of total 472

Search options

Article: Feeding in Tuberculosis.

Daly, James R L

2023 Volume 63, Issue 8, Page(s) 440–444

Language	English
Publishing date	2023-03-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	426473-3
ISSN	1040-3817
ISSN	1040-3817
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

AMP -385/400-: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Endosomes, receptors, and viruses.

Daly, James L

Science (New York, N.Y.)

2022 Volume 378, Issue 6622, Page(s) 845

Abstract: Mechanisms of infection are deciphered at the host-pathogen interface. ...

Abstract	Mechanisms of infection are deciphered at the host-pathogen interface.
MeSH term(s)	Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Endosomes/virology ; Host-Pathogen Interactions/drug effects ; Neuropilin-1/antagonists & inhibitors ; Receptors, Virus/antagonists & inhibitors ; SARS-CoV-2/drug effects ; SARS-CoV-2/physiology ; trans-Golgi Network/virology ; Virus Internalization/drug effects ; Humans
Chemical Substances	Antiviral Agents ; Neuropilin-1 (144713-63-3) ; NRP1 protein, human ; Receptors, Virus
Language	English
Publishing date	2022-11-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.adf4469
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 27: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 77: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Out of the ESCPE room: Emerging roles of endosomal SNX-BARs in receptor transport and host-pathogen interaction.

Simonetti, Boris / Daly, James L / Cullen, Peter J

Traffic (Copenhagen, Denmark)

2023 Volume 24, Issue 6, Page(s) 234–250

Abstract: Several functions of the human cell, such as sensing nutrients, cell movement and interaction with the surrounding environment, depend on a myriad of transmembrane proteins and their associated proteins and lipids (collectively termed "cargoes"). To ... ...

Abstract	Several functions of the human cell, such as sensing nutrients, cell movement and interaction with the surrounding environment, depend on a myriad of transmembrane proteins and their associated proteins and lipids (collectively termed "cargoes"). To successfully perform their tasks, cargo must be sorted and delivered to the right place, at the right time, and in the right amount. To achieve this, eukaryotic cells have evolved a highly organized sorting platform, the endosomal network. Here, a variety of specialized multiprotein complexes sort cargo into itineraries leading to either their degradation or their recycling to various organelles for further rounds of reuse. A key sorting complex is the Endosomal SNX-BAR Sorting Complex for Promoting Exit (ESCPE-1) that promotes the recycling of an array of cargos to the plasma membrane and/or the trans-Golgi network. ESCPE-1 recognizes a hydrophobic-based sorting motif in numerous cargoes and orchestrates their packaging into tubular carriers that pinch off from the endosome and travel to the target organelle. A wide range of pathogens mimic this sorting motif to hijack ESCPE-1 transport to promote their invasion and survival within infected cells. In other instances, ESCPE-1 exerts restrictive functions against pathogens by limiting their replication and infection. In this review, we discuss ESCPE-1 assembly and functions, with a particular focus on recent advances in the understanding of its role in membrane trafficking, cellular homeostasis and host-pathogen interaction.
MeSH term(s)	Humans ; Host-Pathogen Interactions ; Sorting Nexins/metabolism ; Endosomes/metabolism ; Multiprotein Complexes/metabolism ; trans-Golgi Network/metabolism ; Salmonella typhimurium/metabolism ; Chlamydia trachomatis/metabolism ; Viruses/metabolism ; Receptors, Cell Surface/metabolism ; Protein Transport
Chemical Substances	Sorting Nexins ; Multiprotein Complexes ; Receptors, Cell Surface
Language	English
Publishing date	2023-04-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1483852-7
ISSN	1600-0854 ; 1398-9219
ISSN (online)	1600-0854
ISSN	1398-9219
DOI	10.1111/tra.12885
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5634: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Endoplasmic Reticulum-Endosome Contact Sites: Specialized Interfaces for Orchestrating Endosomal Tubule Fission?

Daly, James L / Cullen, Peter J

Biochemistry

2018 Volume 57, Issue 49, Page(s) 6738–6740

MeSH term(s)	Animals ; Binding Sites ; Endoplasmic Reticulum/chemistry ; Endoplasmic Reticulum/metabolism ; Endosomes/chemistry ; Endosomes/metabolism ; Humans ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Models, Biological ; Protein Interaction Domains and Motifs
Chemical Substances	Membrane Proteins
Language	English
Publishing date	2018-11-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1108-3
ISSN	1520-4995 ; 0006-2960
ISSN (online)	1520-4995
ISSN	0006-2960
DOI	10.1021/acs.biochem.8b01176
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 217: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Use of Evidence-Based Interventions to Promote Healthy Weight, Nutrition, and Physical Activity in Community Health Improvement Plans from Large Local Health Departments.

Dupuis, Roxanne / Reiner, Jennifer F / Silver, Santana / Barrett, Jessica L / Daly, James G / Lee, Rebekka M / Gortmaker, Steven L / Cradock, Angie L

Journal of public health management and practice : JPHMP

2023 Volume 29, Issue 5, Page(s) 640–645

Abstract: We sought to identify evidence-based healthy weight, nutrition, and physical activity strategies related to obesity prevention in large local health department (LHD) Community Health Improvement Plans (CHIPs). We analyzed the content of the most recent, ... ...

Abstract	We sought to identify evidence-based healthy weight, nutrition, and physical activity strategies related to obesity prevention in large local health department (LHD) Community Health Improvement Plans (CHIPs). We analyzed the content of the most recent, publicly available plans from 72 accredited LHDs serving a population of at least 500 000 people. We matched CHIP strategies to the County Health Rankings and Roadmaps' What Works for Health (WWFH) database of interventions. We identified 739 strategies across 55 plans, 62.5% of which matched a "WWFH intervention" rated for effectiveness on diet and exercise outcomes. Among the 20 most commonly identified WWFH interventions in CHIPs, 10 had the highest evidence for effectiveness while 4 were rated as likely to decrease health disparities according to WWFH. Future prioritization of strategies by health agencies could focus on strategies with the strongest evidence for promoting healthy weight, nutrition, and physical activity outcomes and reducing health disparities.
MeSH term(s)	Humans ; Public Health ; Exercise ; Obesity/epidemiology ; Obesity/prevention & control ; Nutritional Status ; Evidence-Based Medicine ; Local Government
Language	English
Publishing date	2023-06-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	2027860-3
ISSN	1550-5022 ; 1078-4659
ISSN (online)	1550-5022
ISSN	1078-4659
DOI	10.1097/PHH.0000000000001778
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5302: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Evaluation of two temperature storage conditions for full blood count samples from Lifeblood's donors.

Jacko, Georgina / Green, Anna / Lycett, Leo / Ismay, Sue / Peberdy, James / Daly, James

Transfusion medicine (Oxford, England)

2023 Volume 33, Issue 3, Page(s) 221–226

Abstract: Background and objectives: Lifeblood completes full blood count samples for selected donors to assess their suitability for future donations. Removing the current practice for refrigerated (2-8°C) storage and aligning with room temperature (20-24°C) ... ...

Abstract	Background and objectives: Lifeblood completes full blood count samples for selected donors to assess their suitability for future donations. Removing the current practice for refrigerated (2-8°C) storage and aligning with room temperature (20-24°C) storage of other donor blood samples would produce significant efficiencies in blood donor centres. This study aimed to compare full blood count results under two temperature conditions. Materials and methods: Paired full blood count samples were collected from 250 whole blood or plasma donors. These were stored either refrigerated or room temperature for testing on arrival at the processing centre and the following day. The primary outcomes of interest included differences between mean cell volume, haematocrit, platelet count, white cell and differential counts, and the need to produce blood films, based on existing Lifeblood criteria. Results: A statistically significant (p < 0.05) difference for most full blood count parameters results was found between the two temperature conditions. The number of blood films required was similar under each temperature condition. Conclusion: The clinical significance of the small numerical differences in results is considered minimal. Furthermore, the number of blood films required remained similar under either temperature condition. Given the significant reductions in time, processing and costs associated with room temperature over refrigerated processing, we recommend a further pilot study to monitor the broader impacts, with the intent to implement national storage of full blood count samples at room temperature within Lifeblood.
MeSH term(s)	Humans ; Temperature ; Pilot Projects ; Blood Cell Count/methods ; Hematocrit ; Platelet Count
Language	English
Publishing date	2023-03-02
Publishing country	England
Document type	Journal Article
ZDB-ID	1067989-3
ISSN	1365-3148 ; 0958-7578
ISSN (online)	1365-3148
ISSN	0958-7578
DOI	10.1111/tme.12962
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3177: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A Case Study of Delayed Action PIR Urinal-Controls in a University Setting and Their Impact before, during and after COVID-19

James E. M. Daly / Devendra P. Saroj / Jonathan L. Chenoweth / Thomas Parrott

Sustainability, Vol 14, Iss 15506, p

2022 Volume 15506

Abstract: ... during lockdowns saving 98,000 L/day on average across the study. ...

Abstract	This study looks at the application of delayed action Passive Infrared (PIR) sensors in the control of water use for urinal flushing. In this we briefly review the literature on urinal controls before reviewing four different approaches to PIR urinal controls. Existing literature discusses some of the pros and cons of different types of urinal control. However, the literature does not consider the differences that occur within individual approaches, based on the way controls operate. This study was initiated at the University of Surrey during 2019 following a water saving audit, in an attempt to bring down one of their largest users of water. This paper therefore aims to identify the most effective way to reduce water consumption of urinal systems, through retro-fitting PIR control systems within the variety of settings across university campuses. This paper also reviews the different reductions achieved over periods of differing use, during term-time, holidays, COVID-19 lockdowns, and the ‘new normal’. It found that grouped delayed action flushing was the most effective form of urinal control for reducing water use. It, achieved a 59–64% adjusted reduction during non-COVID-19 periods, and a 35% reduction against the control group during lockdowns saving 98,000 L/day on average across the study.
Keywords	urinal ; Passive Infrared (PIR) ; water conservation ; water efficiency ; campus ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Correction: Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.

Demidova, Elena V / Serebriiskii, Ilya G / Vlasenkova, Ramilia / Kelow, Simon / Andrake, Mark D / Hartman, Tiffiney R / Kent, Tatiana / Virtucio, James / Rosen, Gail L / Pomerantz, Richard T / Dunbrack, Roland L / Golemis, Erica A / Hall, Michael J / Chen, David Y T / Daly, Mary B / Arora, Sanjeevani

BMC genomics

2023 Volume 24, Issue 1, Page(s) 388

Language	English
Publishing date	2023-07-10
Publishing country	England
Document type	Published Erratum
ZDB-ID	2041499-7
ISSN	1471-2164 ; 1471-2164
ISSN (online)	1471-2164
ISSN	1471-2164
DOI	10.1186/s12864-023-09486-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Evaluation of efforts to reduce sodium and ensure access to healthier beverages in four healthcare settings in Massachusetts, US 2016-2018.

Cradock, Angie L / Barrett, Jessica L / Daly, James G / Mozaffarian, Rebecca S / Stoddard, John / Her, Meg / Etingoff, Kim / Lee, Rebekka M

Preventive medicine reports

2022 Volume 27, Page(s) 101788

Abstract: Considerable science links diets lower in sodium and sugar-sweetened beverage consumption with better health outcomes. This study describes the evaluation process and outcomes of intervention strategies to reduce sodium in foods and sugar in beverages as ...

Abstract	Considerable science links diets lower in sodium and sugar-sweetened beverage consumption with better health outcomes. This study describes the evaluation process and outcomes of intervention strategies to reduce sodium in foods and sugar in beverages as part of a collaborative partnership between state public health, academic, community, and healthcare partners in Massachusetts, US. This quasi-experimental, pre-post study used nutrient data linked to observations of foods and beverages available in cafeterias and vending machines in four community healthcare settings to inform intervention strategies and evaluate changes. At post-assessment, beverages with no or very low sugar were significantly more prevalent in vending machines (OR = 1.93, p < 0.001) and cafeterias (OR = 1.83, p = 0.01) and low-sodium packaged foods were significantly more prevalent in cafeterias (OR = 2.45, p < 0.001), but not vending machines. These types of partnerships and tailored feedback and technical assistance strategies may support healthier food and beverage options within healthcare settings that serve patients, their families, and employees each day.
Language	English
Publishing date	2022-04-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2785569-7
ISSN	2211-3355
ISSN	2211-3355
DOI	10.1016/j.pmedr.2022.101788
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health.

Daly, James L / Danson, Chris M / Lewis, Philip A / Zhao, Lu / Riccardo, Sara / Di Filippo, Lucio / Cacchiarelli, Davide / Lee, Daehoon / Cross, Stephen J / Heesom, Kate J / Xiong, Wen-Cheng / Ballabio, Andrea / Edgar, James R / Cullen, Peter J

Nature communications

2023 Volume 14, Issue 1, Page(s) 3086

Abstract: Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including ... ...

Abstract	Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including Parkinson's and Alzheimer's diseases, manifests in complex cellular phenotypes, though the precise nature of this dysfunction, and its relation to neurodegeneration, remain unclear. Here, we perform an integrated multi-omics approach to provide precise insight into the impact of Retromer dysfunction on endo-lysosomal health and homeostasis within a human neuroglioma cell model. We quantify widespread changes to the lysosomal proteome, indicative of broad lysosomal dysfunction and inefficient autophagic lysosome reformation, coupled with a reconfigured cell surface proteome and secretome reflective of increased lysosomal exocytosis. Through this global proteomic approach and parallel transcriptomic analysis, we provide a holistic view of Retromer function in regulating lysosomal homeostasis and emphasise its role in neuroprotection.
MeSH term(s)	Humans ; Neuroprotection ; Multiomics ; Proteome/metabolism ; Proteomics ; Endosomes/metabolism ; Protein Transport/physiology ; Lysosomes/metabolism
Chemical Substances	Proteome
Language	English
Publishing date	2023-05-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-023-38719-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito