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  1. Article ; Online: The Importance of the Morel Emotional Numbing Test Instructions: A Diagnosis Threat Induction Study.

    Williamson, Emily S / Arentsen, Timothy J / Roper, Brad L / Pedersen, Heather A / Shultz, Laura A / Crouse, Ellen M

    Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    2023  Volume 39, Issue 1, Page(s) 35–50

    Abstract: Objective: Marketed as a validity test that detects feigning of posttraumatic stress disorder (PTSD), the Morel Emotional Numbing Test for PTSD (MENT) instructs examinees that PTSD may negatively affect performance on the measure. This study explored ... ...

    Abstract Objective: Marketed as a validity test that detects feigning of posttraumatic stress disorder (PTSD), the Morel Emotional Numbing Test for PTSD (MENT) instructs examinees that PTSD may negatively affect performance on the measure. This study explored the potential that MENT performance depends on inclusion of "PTSD" in its instructions and the nature of the MENT as a performance validity versus a symptom validity test (PVT/SVT).
    Method: 358 participants completed the MENT as a part of a clinical neuropsychological evaluation. Participants were either administered the MENT with the standard instructions (SIs) that referenced "PTSD" or revised instructions (RIs) that did not. Others were administered instructions that referenced "ADHD" rather than PTSD (AI). Comparisons were conducted on those who presented with concerns for potential traumatic-stress related symptoms (SI vs. RI-1) or attention deficit (AI vs. RI-2).
    Results: Participants in either the SI or AI condition produced more MENT errors than those in their respective RI conditions. The relationship between MENT errors and other S/PVTs was significantly stronger in the SI: RI-1 comparison, such that errors correlated with self-reported trauma-related symptoms in the SI but not RI-1 condition. MENT failure also predicted PVT failure at nearly four times the rate of SVT failure.
    Conclusions: Findings suggest that the MENT relies on overt reference to PTSD in its instructions, which is linked to the growing body of literature on "diagnosis threat" effects. The MENT may be considered a measure of suggestibility. Ethical considerations are discussed, as are the construct(s) measured by PVTs versus SVTs.
    MeSH term(s) Humans ; Neuropsychological Tests ; Malingering/diagnosis ; Malingering/psychology ; Emotions ; Stress Disorders, Post-Traumatic/diagnosis ; Stress Disorders, Post-Traumatic/psychology
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632972-x
    ISSN 1873-5843 ; 0887-6177
    ISSN (online) 1873-5843
    ISSN 0887-6177
    DOI 10.1093/arclin/acad048
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  2. Article ; Online: Erosions on T1-weighted MRI vs Radiography of Sacroiliac Joints in Recent-onset Axial SpA: 2-year Data (EMBARK Trial and DESIR Cohort).

    Maksymowych, Walter P / Claudepierre, Pascal / de Hooge, Manouk / Lambert, Robert G / Landewé, Robert / Molto, Anna / van der Heijde, Désirée / Bukowski, Jack F / Jones, Heather / Pedersen, Ron / Szumski, Annette / Vlahos, Bonnie / Dougados, Maxime

    The Journal of rheumatology

    2024  

    Abstract: Objective: To (1) compare the capacity to detect sacroiliac joint (SIJ) erosions and baseline-to-Week-104 change in erosions between magnetic resonance imaging (MRI) and radiographs in recent-onset axial spondyloarthritis (axSpA); (2) compare treatment ... ...

    Abstract Objective: To (1) compare the capacity to detect sacroiliac joint (SIJ) erosions and baseline-to-Week-104 change in erosions between magnetic resonance imaging (MRI) and radiographs in recent-onset axial spondyloarthritis (axSpA); (2) compare treatment discriminatory capacities of MRI and radiographic scores for erosion detection in patients receiving etanercept in the EMBARK trial vs controls in the DESIR cohort.
    Methods: Anonymized SIJ MRI and radiographs were assessed at patient and joint surface levels. Three readers evaluated MRI; 3 different readers evaluated radiographs. Final scores for comparison of radiographs and MRI for detection of erosions were assigned based on agreement of ≥2 of 3 readers' assessments.
    Results: At baseline, discordance in erosion detection between imaging methods was more frequent for MRI erosions in the absence of radiographic erosions (48/224 [21.4%] patients) than for radiographic erosions in the absence of MRI erosions (14/224 [6.3%] patients; P<0.001). After 104 weeks, decrease in erosions was observed on MRI but not radiographs in 49 (22.2%) patients and on radiographs but not MRI in 6 (2.7%) (P<0.001). In the treatment-discriminant capacity analysis, the largest standardized differences between etanercept and control cohorts at Week 104 were changes in Spondyloarthritis Research Consortium of Canada MRI erosion discrete score, erosion average score, and meeting the modified New York criteria on radiographs, with unadjusted/adjusted Hedge's G effect sizes of 0.40/0.50, 0.40/0.56, and 0.40/0.43, respectively.
    Conclusion: In recent-onset axSpA, SIJ erosions and erosion change were observed more frequently on MRI than radiography. The significance of interval improvement of MRI erosions warrants further research.
    Language English
    Publishing date 2024-02-15
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.2023-0906
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  3. Article ; Online: Effect of an Electronic Order Set on Newborn Hepatitis B Immunization Rates.

    Pedersen, Daniel / Rodriguez, Angelina / Oyesanmi, Olu / Schramm, Heather / King, Michael

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 6, Page(s) 507–512

    Abstract: Objective: Hepatitis B is an infectious deoxyribonucleic acid virus which can cause significant morbidity and mortality. There is no current definitive treatment, however in the United States immunization is widely available. A paper published by the ... ...

    Abstract Objective: Hepatitis B is an infectious deoxyribonucleic acid virus which can cause significant morbidity and mortality. There is no current definitive treatment, however in the United States immunization is widely available. A paper published by the Advisory Committee on Immunization Practices/Centers for Disease Control (ACIP/CDC) in 2018 made updated recommendations regarding vaccination practices in the United States. The most notable change made was that all healthy newborns weighing ≥2000 g with a negative hepatitis B-status mother should receive hepatitis B immunization within 24 hours of birth. This quality improvement project studied the effect of the electronic medical record newborn admission order set, altered to reflect current societal recommendations, and the resulting newborn hepatitis B immunization rates.
    Methods: The electronic medical record admission order set was modified to reflect the most recent recommendations made by ACIP/CDC. Hepatitis B immunization rates were then analyzed prior to and following the order set changes.
    Results: The most significant effect was seen in the overall rate of hepatitis B immunization achieved prior to hospital discharge. In the 12 months before order set modifications were implemented the rate was 9.5%. Following electronic medical record changes it improved to over 90%. In addition, the immunization rate performed within the first 24 hours increased from 74.1% to 91.1%. Finally, these records were made accessible to outpatient providers via a statewide immunization database.
    Conclusions: This project serves as an example of how modifying order sets can have a dramatic effect on ordering practices and therefore allows for quality improvement.
    Language English
    Publishing date 2020-12-29
    Publishing country United States
    Document type Journal Article
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1152
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  4. Article ; Online: Evaluating the Impact of the COVID-19-Related Public Health Restrictions on Access to Digital Sexually Transmitted and Blood-Borne Infection Testing in British Columbia, Canada: An Interrupted Time Series Analysis.

    Iyamu, Ihoghosa / Pedersen, Heather / Ablona, Aidan / Chang, Hsiu-Ju / Worthington, Catherine / Grace, Daniel / Grennan, Troy / Wong, Jason / Salmon, Amy / Koehoorn, Mieke / Gilbert, Mark

    Sexually transmitted diseases

    2023  Volume 50, Issue 9, Page(s) 595–602

    Abstract: Background: Evidence of long-term impacts of COVID-19-related public health restrictions on digital sexually transmitted and blood-borne infection (STBBI) testing utilization is limited. We assessed these impacts on GetCheckedOnline (a digital testing ... ...

    Abstract Background: Evidence of long-term impacts of COVID-19-related public health restrictions on digital sexually transmitted and blood-borne infection (STBBI) testing utilization is limited. We assessed these impacts on GetCheckedOnline (a digital testing resource for STBBIs) relative to all STBBI tests in British Columbia (BC).
    Methods: Interrupted time series analyses were conducted using GetCheckedOnline program data comparing monthly test episodes (STBBI tests per requisition) among BC residents, stratified by BC region, and testers' sociodemographic and sexual risk profiles, for the prepandemic (March 2018-February 2020) and pandemic periods (March 2020-October 2021). Trends in GetCheckedOnline testing per 100 STBBI tests in BC regions with GetCheckedOnline were analyzed. Each outcome was modeled using segmented generalized least squared regression.
    Results: Overall, 17,215 and 22,646 test episodes were conducted in the prepandemic and pandemic periods. Monthly GetCheckedOnline test episodes reduced immediately after restrictions. By October 2021 (end of the pandemic period), monthly GetCheckedOnline testing increased by 21.24 test episodes per million BC residents (95% confidence interval, -11.88 to 54.84), and GetCheckedOnline tests per 100 tests in corresponding BC regions increased by 1.10 (95% confidence interval, 0.02 to 2.17) above baseline trends. After initial increases among users at higher STBBI risk (symptomatic testers/testers reporting sexual contacts with STBBIs), testing decreased below baseline trends later in the pandemic, whereas monthly GetCheckedOnline testing increased among people 40 years or older, men who have sex with men, racialized minorities, and first-time testers via GetCheckedOnline.
    Conclusions: Sustained increases in utilization of digital STBBI testing during the pandemic suggest fundamental changes in STBBI testing in BC, highlighting the need for accessible and appropriate digital testing, especially for those most affected by STBBIs.
    MeSH term(s) Humans ; Male ; Blood-Borne Infections/diagnosis ; Blood-Borne Infections/epidemiology ; British Columbia/epidemiology ; COVID-19/prevention & control ; Homosexuality, Male ; Interrupted Time Series Analysis ; Public Health ; Sexual and Gender Minorities ; Sexually Transmitted Diseases/diagnosis ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/prevention & control
    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/OLQ.0000000000001833
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  5. Article ; Online: Community-integrated self-collected HPV-based cervix screening in a low-resource rural setting: a pragmatic, cluster-randomized trial.

    Gottschlich, Anna / Payne, Beth A / Trawin, Jessica / Albert, Arianne / Jeronimo, Jose / Mitchell-Foster, Sheona / Mithani, Nadia / Namugosa, Ruth / Naguti, Priscilla / Pedersen, Heather / Rawat, Angeli / Simelela, Princess Nothemba / Singer, Joel / Smith, Laurie W / van Niekerk, Dirk / Orem, Jackson / Nakisige, Carolyn / Ogilvie, Gina

    Nature medicine

    2023  Volume 29, Issue 4, Page(s) 927–935

    Abstract: Effective approaches to improve coverage of self-collected human papillomavirus (HPV)-based cervix screening (SCS) as well as attendance at treatment for HPV-positive participants are needed to inform policy on optimal integration of cervical cancer ... ...

    Abstract Effective approaches to improve coverage of self-collected human papillomavirus (HPV)-based cervix screening (SCS) as well as attendance at treatment for HPV-positive participants are needed to inform policy on optimal integration of cervical cancer screening programs within existing infrastructure in low-resource settings. ASPIRE Mayuge was a pragmatic cluster-randomized trial in rural Mayuge district, Uganda, comparing the superiority of two recruitment implementation strategies for SCS: Door-to-Door versus Community Health Day. Villages were randomized (unblinded) to a strategy, and participants aged 25-49 years with no previous history of hysterectomy or treatment for cervical cancer or pre-cancer were eligible. Participants completed a survey and participated in SCS. The primary outcome was rate of attendance at treatment after a positive SCS. The trial randomized 31 villages and 2,019 participants included in these analyses (Door-to-Door: 16 clusters, 1,055 participants; Community Health Day: 15 clusters, 964 participants). Among HPV-positive participants, attendance at treatment rates were 75% (Door-to-Door) and 67% (Community Health Day) (P = 0.049). Participants in the Community Health Day intervention were less likely to attend treatment compared to Door-to-Door (risk ratio = 0.78, 95% confidence interval: 0.64-0.96). No adverse events were reported. Policymakers in low-resource settings can use these results to guide implementation of SCS programs. ISRCTN registration: 12767014 . ClinicalTrials.gov registration: NCT04000503 .
    MeSH term(s) Female ; Humans ; Cervix Uteri ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/epidemiology ; Uterine Cervical Neoplasms/therapy ; Early Detection of Cancer/methods ; Papillomavirus Infections/diagnosis ; Mass Screening/methods ; Papillomaviridae
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02288-6
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  6. Article ; Online: Effects of Training on Use of Stimulant Diversion Prevention Strategies by Pediatric Primary Care Providers: Results from a Cluster-Randomized Trial.

    McGuier, Elizabeth A / Kolko, David J / Pedersen, Sarah L / Kipp, Heidi L / Joseph, Heather M / Lindstrom, Rachel A / Bauer, Daniel J / Subramaniam, Geetha A / Molina, Brooke S G

    Prevention science : the official journal of the Society for Prevention Research

    2022  Volume 23, Issue 7, Page(s) 1299–1307

    Abstract: Pediatric primary care is a promising setting for reducing diversion of stimulant medications for ADHD. We tested if training pediatric primary care providers (PCPs) increased use of diversion prevention strategies with adolescents with ADHD. The study ... ...

    Abstract Pediatric primary care is a promising setting for reducing diversion of stimulant medications for ADHD. We tested if training pediatric primary care providers (PCPs) increased use of diversion prevention strategies with adolescents with ADHD. The study was a cluster-randomized trial in 7 pediatric primary care practices. Participants were pediatric PCPs (N = 76) at participating practices. Practices were randomized to a 1-h training in stimulant diversion prevention or treatment-as-usual. At baseline, 6 months, 12 months, and 18 months, PCPs rated how often they used four categories of strategies: patient/family education, medication management/monitoring, assessment of mental health symptoms/functioning, and assessment of risky behaviors. They completed measures of attitudes, implementation climate, knowledge/skill, and resource constraints. Generalized Estimating Equations estimated differences in outcomes by condition. Mediation analyses tested if changes in knowledge/skill mediated training effects on strategy use. PCPs in the intervention condition reported significantly greater use of patient/family education strategies at all follow-up time points. There were no differences between conditions in medication management, assessment of mental health symptoms/functioning, or assessment of risky behaviors. At 6 months, PCPs in the intervention condition reported more positive attitudes toward diversion prevention, stronger implementation climate, greater knowledge/skill, and less resource constraints. Differences in knowledge/skill persisted at 12 months and 18 months. Brief training in stimulant diversion had substantial and enduring effects on PCPs' self-reported knowledge/skill and use of patient/family education strategies to prevent diversion. Training had modest effects on attitudes, implementation climate, and resource constraints and did not change use of strategies related to medication management and assessment of mental health symptoms/functioning and risky behaviors. Changes in knowledge/skill accounted for 49% of the total effect of training on use of patient/family education strategies. Trial registration This trial is registered on ClinicalTrials.gov (NCT03080259). Posted March 15, 2017.
    MeSH term(s) Adolescent ; Child ; Humans ; Mental Disorders ; Mental Health ; Primary Health Care
    Language English
    Publishing date 2022-08-11
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 2251270-6
    ISSN 1573-6695 ; 1389-4986
    ISSN (online) 1573-6695
    ISSN 1389-4986
    DOI 10.1007/s11121-022-01411-2
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  7. Article ; Online: Rumination, risk, and response: a qualitative analysis of sexual health anxiety among online sexual health chat service users.

    Watt, Sarah / Salway, Travis / Gómez-Ramírez, Oralia / Ablona, Aidan / Barton, Lindsay / Chang, Hsiu-Ju / Pedersen, Heather / Haag, Devon / LeMoult, Joelle / Gilbert, Mark

    Sexual health

    2022  Volume 19, Issue 3, Page(s) 182–191

    Abstract: Background: Anxiety is common among sexual health service users. Accessible, anonymous online sexual health services may offer opportunities to connect users with mental health services, but little is known about anxiety in these settings. We sought to ... ...

    Abstract Background: Anxiety is common among sexual health service users. Accessible, anonymous online sexual health services may offer opportunities to connect users with mental health services, but little is known about anxiety in these settings. We sought to characterise expressions of anxiety among chat users and nurse responses to anxiety.
    Methods: We conducted inductive thematic analysis of transcripts from an anonymous online sexual health chat service moderated by sexual health nurses.
    Results: Among chat users, we identified: worry, anxiety, and emotional distress, particularly regarding HIV transmission risk, testing, and symptoms; exaggerated appraisal of HIV-transmission risk associated with sex-related shame and stigma; and patterns of anxiety that were unresolved by HIV education or testing interventions. Although nurses recognised and acknowledged anxiety, their responses to this anxiety varied; some provided anxiety management information, while others offered sexual health education and risk assessment.
    Conclusions: Targeted interventions addressing HIV-related stigma and anxiety among online sexual health service users are needed to facilitate connections to appropriate mental health supports.
    MeSH term(s) Anxiety/psychology ; HIV Infections/diagnosis ; Humans ; Mental Health ; Sexual Health ; Social Stigma
    Language English
    Publishing date 2022-05-22
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2256731-8
    ISSN 1449-8987 ; 1448-5028
    ISSN (online) 1449-8987
    ISSN 1448-5028
    DOI 10.1071/SH21198
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  8. Article ; Online: LPS differentially affects expression of CD14 and CCR2 in monocyte subsets of Post-STEMI patients with hyperglycemia.

    Blanks, Anson M / Pedersen, Lauren N / Caslin, Heather L / Mihalick, Virginia L / Via, Jeremy / Canada, Justin M / Van Tassell, Benjamin / Carbone, Salvatore / Abbate, Antonio / Lee Franco, R

    Diabetes research and clinical practice

    2022  Volume 191, Page(s) 110077

    Abstract: Aims: Following ST-segment elevation myocardial infarction (STEMI), recruitment and activation of monocytes [classical (CD14: Methods: Post-STEMI subjects were identified as normal random glucose (NG, <98 mg/dL, n = 13) or impaired random glucose (IG, ...

    Abstract Aims: Following ST-segment elevation myocardial infarction (STEMI), recruitment and activation of monocytes [classical (CD14
    Methods: Post-STEMI subjects were identified as normal random glucose (NG, <98 mg/dL, n = 13) or impaired random glucose (IG, ≥98 mg/dL, n = 26) and monocytes were analyzed for non-activated and LPS-activated (1 µg/mL for 4 h) CCR2 and CD14 expression.
    Results: Non-activated intermediate monocytes from IG showed decreased CD14 expression when compared to NG, which was maintained following LPS-activation. The NG group showed a larger absolute reduction in classical CCR2 expression, leading to a significant difference between NG and IG following LPS-activation.
    Conclusion: Results suggest a heightened response to pro-inflammatory activation in IG following STEMI, which may impair or delay post-STEMI myocardial healing, and thus increase the incidence of chronic heart failure. NIH 1R34HL121402.
    MeSH term(s) Blood Glucose/metabolism ; Humans ; Hyperglycemia/metabolism ; Lipopolysaccharide Receptors/immunology ; Lipopolysaccharides/pharmacology ; Monocytes/metabolism ; Receptors, CCR/metabolism ; Receptors, CCR2/metabolism ; Receptors, IgG/metabolism ; ST Elevation Myocardial Infarction
    Chemical Substances Blood Glucose ; CCR2 protein, human ; CD14 protein, human ; Lipopolysaccharide Receptors ; Lipopolysaccharides ; Receptors, CCR ; Receptors, CCR2 ; Receptors, IgG
    Language English
    Publishing date 2022-09-08
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2022.110077
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  9. Article ; Online: ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts.

    Hyun, Insoo / Clayton, Ellen Wright / Cong, Yali / Fujita, Misao / Goldman, Steven A / Hill, Lori R / Monserrat, Nuria / Nakauchi, Hiromitsu / Pedersen, Roger A / Rooke, Heather M / Takahashi, Jun / Knoblich, Jürgen A

    Stem cell reports

    2021  Volume 16, Issue 6, Page(s) 1409–1415

    Abstract: The newly revised 2021 ISSCR Guidelines for Stem Cell Research and Clinical Translation includes scientific and ethical guidance for the transfer of human pluripotent stem cells and their direct derivatives into animal models. In this white paper, the ... ...

    Abstract The newly revised 2021 ISSCR Guidelines for Stem Cell Research and Clinical Translation includes scientific and ethical guidance for the transfer of human pluripotent stem cells and their direct derivatives into animal models. In this white paper, the ISSCR subcommittee that drafted these guidelines for research involving the use of nonhuman embryos and postnatal animals explains and summarizes their recommendations.
    MeSH term(s) Animals ; Chimera ; Embryo Research/ethics ; Humans ; Pluripotent Stem Cells ; Practice Guidelines as Topic ; Societies, Scientific/ethics ; Societies, Scientific/standards ; Stem Cell Research/ethics ; Stem Cell Transplantation/ethics ; Stem Cell Transplantation/standards
    Language English
    Publishing date 2021-05-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2720528-9
    ISSN 2213-6711 ; 2213-6711
    ISSN (online) 2213-6711
    ISSN 2213-6711
    DOI 10.1016/j.stemcr.2021.05.005
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  10. Article ; Online: Use of Stimulant Diversion Prevention Strategies in Pediatric Primary Care and Associations With Provider Characteristics.

    McGuier, Elizabeth A / Kolko, David J / Joseph, Heather M / Kipp, Heidi L / Lindstrom, Rachel A / Pedersen, Sarah L / Subramaniam, Geetha A / Molina, Brooke S G

    The Journal of adolescent health : official publication of the Society for Adolescent Medicine

    2021  Volume 68, Issue 4, Page(s) 808–815

    Abstract: Purpose: Diversion of stimulant medications for ADHD is a prevalent problem. Pediatric primary care providers (PCPs) are well-positioned to reduce diversion risk among adolescents prescribed stimulants, but little is known about their use of prevention ... ...

    Abstract Purpose: Diversion of stimulant medications for ADHD is a prevalent problem. Pediatric primary care providers (PCPs) are well-positioned to reduce diversion risk among adolescents prescribed stimulants, but little is known about their use of prevention strategies. The objectives of this study were to describe the frequency with which pediatric PCPs use diversion prevention strategies and examine potential determinants (facilitators and barriers) of strategy use.
    Methods: Participants were pediatric PCPs (N = 76) participating in a randomized controlled trial of stimulant diversion prevention strategies. At baseline, before randomization, PCPs rated the frequency with which they used specific strategies in each of four categories: patient/family education, medication management/monitoring, assessment of mental health symptoms/functioning, and assessment of risky behaviors. They completed measures of attitudes toward diversion prevention, subjective norms (i.e., implementation climate), and perceived behavioral control (i.e., knowledge/skill, resource constraints). Associations between determinants and strategy use were tested with correlational and regression analyses.
    Results: PCPs used strategies for assessing mental health symptoms/functioning most frequently and patient/family education strategies least frequently. Attitudes about the effectiveness of diversion prevention, implementation climate, knowledge/skill, and resource constraints were positively correlated with the use of at least one category of strategies. In regression analysis, PCP knowledge/skill was positively associated with patient/family education, medication management, and risk assessment strategies.
    Conclusions: Findings suggest that improving knowledge and skill may increase the use of diversion prevention strategies by PCPs. Identifying provider-level determinants of strategy use informs implementation efforts in pediatric primary care and can facilitate efforts to prevent stimulant diversion among adolescents.
    MeSH term(s) Adolescent ; Attention Deficit Disorder with Hyperactivity/drug therapy ; Central Nervous System Stimulants/therapeutic use ; Child ; Health Personnel ; Humans ; Mental Health ; Primary Health Care
    Chemical Substances Central Nervous System Stimulants
    Language English
    Publishing date 2021-01-11
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 1063374-1
    ISSN 1879-1972 ; 1054-139X
    ISSN (online) 1879-1972
    ISSN 1054-139X
    DOI 10.1016/j.jadohealth.2020.12.006
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