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  1. Article ; Online: Samuel Quiroga y Pablo Cayuqueo. (2021). Arte e imagen. El paisaje cultural en Temuco . Chile

    Grettel Andrade-Cambronero

    Cuadernos Inter.c.a.mbio sobre Centroamérica y el Caribe, Vol 19, Iss

    Ediciones UC Temuco.

    2022  Volume 2

    Keywords reseña ; Geography. Anthropology. Recreation ; G ; History America ; E-F
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Universidad de Costa Rica
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Phase separating Rho: a widespread regulatory function of disordered regions in proteins revealed in bacteria.

    Schumbera, Eric / Mier, Pablo / Andrade-Navarro, Miguel A

    Signal transduction and targeted therapy

    2023  Volume 8, Issue 1, Page(s) 253

    MeSH term(s) Proteins/metabolism ; Bacteria/genetics ; Bacteria/metabolism
    Chemical Substances Proteins
    Language English
    Publishing date 2023-06-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2886872-9
    ISSN 2059-3635 ; 2095-9907
    ISSN (online) 2059-3635
    ISSN 2095-9907
    DOI 10.1038/s41392-023-01505-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Conference proceedings: Exoscopic Keyhole Supraorbital Approach for Resection of a Pre-infundibular Craniopharyngioma

    de Andrade, Erion J. / Patel, Arpan / Recinos, Pablo F.

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1780406
    Database Thieme publisher's database

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  4. Article ; Conference proceedings: Keyhole Retractorless Retrosigmoid Approach for a Large Cystic Vestibular Schwannoma

    de Andrade, Erion J. / Recinos, Pablo F.

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1780436
    Database Thieme publisher's database

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  5. Article ; Online: Phase separating Rho

    Eric Schumbera / Pablo Mier / Miguel A. Andrade-Navarro

    Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-

    a widespread regulatory function of disordered regions in proteins revealed in bacteria

    2023  Volume 3

    Keywords Medicine ; R ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
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  6. Article ; Online: Uma aproximação antropológica ingoldiana na elaboração do Plano Diretor Socioespacial da Rocinha – RJ (2005 a 2007)

    Pablo Regis Andrade

    Cadernos NAUI, Vol 10, Iss 19, Pp 339-

    2021  Volume 361

    Abstract: O presente artigo propõe-se a estabelecer uma relação entre o estudo de Habitação de Interesse Social (HIS) aplicado para a Rocinha, Rio de Janeiro, cuja proposta foi coordenada pelo arquiteto Luiz Carlos Toledo durante a elaboração do Plano Diretor ... ...

    Abstract O presente artigo propõe-se a estabelecer uma relação entre o estudo de Habitação de Interesse Social (HIS) aplicado para a Rocinha, Rio de Janeiro, cuja proposta foi coordenada pelo arquiteto Luiz Carlos Toledo durante a elaboração do Plano Diretor Socioespacial da Rocinha (2005 a 2007), e uma visão antropológica entre organismos e meio ambiente baseada em Tim Ingold, considerando a relação sistêmica e sinérgica destes no âmbito do projeto desenvolvido. Num primeiro momento, compreende-se a noção de interesse social no âmbito do Estatuto da Cidade, abordando o contraponto urbanístico que seria a Rocinha com suas autoedificações, para, então, acompanhar a metodologia adotada no referido plano diretor, pautada na participação dos moradores locais. Dentro das questões de edificação, aborda-se a adesão da qualidade arquitetônica para além de uma forma dada, eminentemente técnica, isto é, avançase para a relação de percepção do ambiente como reconstrução de uma realidade natural (saber da arquitetura) em termos de uma metáfora da cultura (o indivíduo historicamente situado), cuja proposição final seria uma linguagem nova para o Programa Minha Casa Minha Vida (PMCMV), numa revisão do trabalho da HIS rumo a uma ecologia da vida. Ecologia da Vida
    Keywords ecologia da vida ; plano diretor socioespacial ; rocinha ; habitação de interesse social ; Social sciences (General) ; H1-99
    Language Portuguese
    Publishing date 2021-12-01T00:00:00Z
    Publisher Universidade Federal de Santa Catarina
    Document type Article ; Online
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  7. Article ; Online: Evolutionary Study of Protein Short Tandem Repeats in Protein Families.

    Mier, Pablo / Andrade-Navarro, Miguel A

    Biomolecules

    2023  Volume 13, Issue 7

    Abstract: Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion. High ... ...

    Abstract Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion. High pressure in a protein family for variation of a given type of repeat might point to their function. Here, we propose the analysis of protein families to calculate protein short tandem repeats (pSTRs) in each protein sequence and assess their variability within the family in terms of number of units. To facilitate this analysis, we developed the pSTR tool, a method to analyze the evolution of protein short tandem repeats in a given protein family by pairwise comparisons between evolutionarily related protein sequences. We evaluated pSTR unit number variation in protein families of 12 complete metazoan proteomes. We hypothesize that families with more dynamic ensembles of repeats could reflect particular roles of these repeats in processes that require more adaptability.
    MeSH term(s) Animals ; Amino Acid Sequence ; Proteome ; Microsatellite Repeats ; Evolution, Molecular
    Chemical Substances Proteome
    Language English
    Publishing date 2023-07-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13071116
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  8. Article: Corrigendum: Women in Neuromodulation: Innovative Contributions to Stereotactic and Functional Neurosurgery.

    Heiden, Petra / Pieczewski, Julia / Andrade, Pablo

    Frontiers in human neuroscience

    2022  Volume 16, Page(s) 859587

    Abstract: This corrects the article DOI: 10.3389/fnhum.2021.756039.]. ...

    Abstract [This corrects the article DOI: 10.3389/fnhum.2021.756039.].
    Language English
    Publishing date 2022-03-17
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2022.859587
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  9. Article: The nucleotide landscape of polyXY regions.

    Mier, Pablo / Andrade-Navarro, Miguel A

    Computational and structural biotechnology journal

    2023  Volume 21, Page(s) 5408–5412

    Abstract: PolyXY regions are compositionally biased regions composed of two different amino acids. They are classified according to the arrangement of the two amino acid types 'X' and 'Y' into direpeats (composed of alternating amino acids, e.g. 'XYXYXY'), joined ( ...

    Abstract PolyXY regions are compositionally biased regions composed of two different amino acids. They are classified according to the arrangement of the two amino acid types 'X' and 'Y' into direpeats (composed of alternating amino acids, e.g. 'XYXYXY'), joined (composed of two consecutive stretches of each amino acid, e.g. 'XXXYYY') and shuffled (other arrangements, e.g., 'XYXXYY'). They have been characterized at the amino acid level in all domains of life, and are described as often found within intrinsically disordered regions. Since DNA replication slippage has been proposed as a driver of repeat variation, and given that some polyXY have a repetitive nature, we hypothesized that characterizing the nucleotide coding of various types of polyXY could give hints about their origin and evolution. To test this, we obtained all polyXY regions in the human transcriptome, categorized them, and studied their coding nucleotide sequences. We observed that polyXY exacerbates the codon biases, and that the similarity between the X and Y codons is higher than in the background proteome. Our results support a general mechanism of emergence and evolution of polyXY from single-codon polyX. PolyXY are revealed as hotspots for replication slippage, particularly those composed of repeats: joined and direpeat polyXY. Inter-conversion to shuffled polyXY disrupts nucleotide repeats and restricts further evolution by replication slippage, a mechanism that we previously observed in polyX. Our results shed light on polyXY composition and should simplify the determination of their functions.
    Language English
    Publishing date 2023-10-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2023.10.054
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  10. Article ; Online: Exoscopic supraorbital approach for a tuberculum sellae meningioma.

    de Andrade, Erion Júnior / Recinos, Pablo F

    Clinical neurology and neurosurgery

    2023  Volume 231, Page(s) 107830

    Abstract: Tuberculum sellae meningiomas are midline anterior skull base tumors and account for approximately 10-15% of all intracranial meningiomas. Clinical presentation of tuberculum sellae meningiomas is mainly characterized by visual deficits due to optic ... ...

    Abstract Tuberculum sellae meningiomas are midline anterior skull base tumors and account for approximately 10-15% of all intracranial meningiomas. Clinical presentation of tuberculum sellae meningiomas is mainly characterized by visual deficits due to optic chiasm compression or optic canal invasion. Treatment options for TSM typically involve surgical resection of the tumor. The relevant microsurgical anatomy of the suprasellar region was discussed. (1,2). Tumor size, anatomical variations can affect the best approach for these tumors, with several approaches been described to access the suprasellar region as pterional, endoscopic endonasal and supraorbital approach that was the choice for this case (3). Besides the surgical corridor, minimally invasive techniques that preserve the surrounding tissue are becoming increasingly popular and are perfectly suited to deep seated lesions. In this article, we present a surgical video of an exoscopic supraorbital approach for resection of a tuberculum sellae meningioma. This is a case of a 42-year-old right-handed female who presented with headaches and progressive vision loss. Patient presented with tumor growth and surgery was indicated. We chose the minimally invasive supraorbital approach and then used the exoscope as magnification tool visualization tool. Gross total resection and decompression of the optic canals was achieved with improvement of visual field deficits.
    MeSH term(s) Humans ; Female ; Adult ; Meningioma/diagnostic imaging ; Meningioma/surgery ; Meningioma/pathology ; Skull Base Neoplasms/surgery ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/surgery ; Meningeal Neoplasms/pathology ; Sella Turcica/diagnostic imaging ; Sella Turcica/surgery ; Sella Turcica/pathology ; Treatment Outcome
    Language English
    Publishing date 2023-06-10
    Publishing country Netherlands
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2023.107830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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