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  1. Article ; Online: Effects of climate change and human activities on vector-borne diseases.

    de Souza, William M / Weaver, Scott C

    Nature reviews. Microbiology

    2024  

    Abstract: Vector-borne diseases are transmitted by haematophagous arthropods (for example, mosquitoes, ticks and sandflies) to humans and wild and domestic animals, with the largest burden on global public health disproportionately affecting people in tropical and ...

    Abstract Vector-borne diseases are transmitted by haematophagous arthropods (for example, mosquitoes, ticks and sandflies) to humans and wild and domestic animals, with the largest burden on global public health disproportionately affecting people in tropical and subtropical areas. Because vectors are ectothermic, climate and weather alterations (for example, temperature, rainfall and humidity) can affect their reproduction, survival, geographic distribution and, consequently, ability to transmit pathogens. However, the effects of climate change on vector-borne diseases can be multifaceted and complex, sometimes with ambiguous consequences. In this Review, we discuss the potential effects of climate change, weather and other anthropogenic factors, including land use, human mobility and behaviour, as possible contributors to the redistribution of vectors and spread of vector-borne diseases worldwide.
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2139054-X
    ISSN 1740-1534 ; 1740-1526
    ISSN (online) 1740-1534
    ISSN 1740-1526
    DOI 10.1038/s41579-024-01026-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Understanding factors associated with COVID-19 vaccination among health care workers using the Diffusion of Innovation Theory.

    D'Souza, Gail C / Pinto, Casey N / Exten, Cara L / Yingst, Jessica M / Foulds, Jonathan / Anderson, Jocelyn / Allen, Rachel / Calo, William A

    American journal of infection control

    2024  Volume 52, Issue 5, Page(s) 509–516

    Abstract: Background: The COVID-19 vaccine was initially offered to frontline health care workers (HCWs), due to the high risk of contracting COVID-19 through occupational exposure to patients. Low HCW vaccine uptake can impact overall community-level vaccine ... ...

    Abstract Background: The COVID-19 vaccine was initially offered to frontline health care workers (HCWs), due to the high risk of contracting COVID-19 through occupational exposure to patients. Low HCW vaccine uptake can impact overall community-level vaccine uptake. This study used the Diffusion of Innovation (DOI) Theory to understand factors related to COVID-19 vaccine uptake in HCWs.
    Methods: We surveyed Pennsylvanian HCWs (excluding Philadelphia) from August 2022 to February 2023. Survey questions inquired about demographics, COVID-19 vaccination status, reasons for receiving/declining the COVID-19 vaccine, and sources of information about the vaccine.
    Results: Participants (n = 3,490) were 85% female, 89% White, and 93% (n = 3,255) reported receiving at least one dose of a COVID-19 vaccine. HCWs were categorized into adopter categories of the DOI Theory: innovators (56%), early adopters (9%), early majority (11%), late majority (7%), and laggards (17%). The major reason that prompted participants to get the vaccine was to protect them against COVID-19 infection (78%), while the major reason for declining the vaccine was due to concern about possible side effects from the vaccine (78%).
    Conclusions: We applied the DOI Theory to characterize adopters and identify factors related to COVID-19 vaccine uptake in HCWs. As updated COVID-19 vaccines are approved for the United States market, our findings may be used to improve vaccine education and communication among HCWs to support vaccine uptake.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2023.11.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (family

    Bamford, Connor G G / de Souza, William M / Parry, Rhys / Gifford, Robert J

    Virus evolution

    2022  Volume 8, Issue 2, Page(s) veac085

    Abstract: Flavivirids ( ... ...

    Abstract Flavivirids (family
    Language English
    Publishing date 2022-09-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2818949-8
    ISSN 2057-1577
    ISSN 2057-1577
    DOI 10.1093/ve/veac085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Evaluating the sensitivity of mortality attributable to pollution to modeling Choices: A case study for Colorado.

    deSouza, Priyanka N / Anenberg, Susan / Fann, Neal / McKenzie, Lisa M / Chan, Elizabeth / Roy, Ananya / Jimenez, Jose L / Raich, William / Roman, Henry / Kinney, Patrick L

    Environment international

    2024  Volume 185, Page(s) 108416

    Abstract: We evaluated the sensitivity of estimated ... ...

    Abstract We evaluated the sensitivity of estimated PM
    MeSH term(s) Air Pollutants/adverse effects ; Air Pollutants/analysis ; Air Pollution/adverse effects ; Air Pollution/analysis ; Particulate Matter/adverse effects ; Particulate Matter/analysis ; Colorado/epidemiology ; Nitrogen Dioxide/analysis ; Environmental Exposure/adverse effects ; Environmental Exposure/analysis
    Chemical Substances Air Pollutants ; Particulate Matter ; Nitrogen Dioxide (S7G510RUBH)
    Language English
    Publishing date 2024-01-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2024.108416
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Serological evidence of hantavirus infection in neotropical bats in an urban area of São Paulo State, Brazil.

    Bueno, Larissa M / Melo, Danilo M / Azevedo, Roberta D / de Souza, William M / Figueiredo, Luiz T M

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2022  Volume 117, Issue 4, Page(s) 297–300

    Abstract: Background: Although hantaviruses have long been associated with rodents, they are also described in other mammalian hosts, such as shrews, moles and bats. Hantaviruses associated with bats have been described in Asian, European and Brazilian species of ...

    Abstract Background: Although hantaviruses have long been associated with rodents, they are also described in other mammalian hosts, such as shrews, moles and bats. Hantaviruses associated with bats have been described in Asian, European and Brazilian species of bats. As these mammals represent the second major mammalian order, and they are the major mammals that inhabit urban areas, it is extremely important to maintain a viral surveillance in these animals. Our aim was to conduct serosurveillance in bats in an urban area in the city of Ribeirão Preto, São Paulo State, Brazil, to contribute to the information about hantaviruses circulation in bats.
    Methods: We analyzed samples from 778 neotropical bat specimens classified into 21 bat species and four different families collected in the urban area of Ribeirão Preto city, from 2014 to 2019 by an ELISA for the detection of IgG antibodies against orthohantavirus.
    Results: We detected IgG-specific antibodies against the nucleoprotein of orthohantavirus in 0.9% (7/778) bats tested, including four Molossus molossus (Pallas' Free-tailed Bat), two Glossophaga soricina (Pallas's Long-tongued Bat) and one Eumops glaucinus (Wagner's mastiff bat).
    Conclusions: Overall, our results show the first serological evidence of hantavirus infection in three common bat species in urban areas.
    MeSH term(s) Animals ; Chiroptera ; Brazil/epidemiology ; Mammals ; Hantavirus Infections/epidemiology ; Hantavirus Infections/veterinary ; Orthohantavirus ; Phylogeny
    Language English
    Publishing date 2022-12-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trac111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Oligo-barcode illuminates holocentric karyotype evolution in

    Mata-Sucre, Yennifer / Parteka, Letícia Maria / Ritz, Christiane M / Gatica-Arias, Andrés / Félix, Leonardo P / Thomas, William Wayt / Souza, Gustavo / Vanzela, André L L / Pedrosa-Harand, Andrea / Marques, André

    Frontiers in plant science

    2024  Volume 15, Page(s) 1330927

    Abstract: Holocentric karyotypes are assumed to rapidly evolve through chromosome fusions and fissions due to the diffuse nature of their centromeres. Here, we took advantage of the recent availability of a chromosome-scale reference genome ... ...

    Abstract Holocentric karyotypes are assumed to rapidly evolve through chromosome fusions and fissions due to the diffuse nature of their centromeres. Here, we took advantage of the recent availability of a chromosome-scale reference genome for
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2024.1330927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Chikungunya: a decade of burden in the Americas.

    de Souza, William M / Ribeiro, Guilherme S / de Lima, Shirlene T S / de Jesus, Ronaldo / Moreira, Filipe R R / Whittaker, Charles / Sallum, Maria Anice M / Carrington, Christine V F / Sabino, Ester C / Kitron, Uriel / Faria, Nuno R / Weaver, Scott C

    Lancet regional health. Americas

    2024  Volume 30, Page(s) 100673

    Abstract: In the Americas, one decade following its emergence in 2013, chikungunya virus (CHIKV) continues to spread and cause epidemics across the region. To date, 3.7 million suspected and laboratory-confirmed chikungunya cases have been reported in 50 countries ...

    Abstract In the Americas, one decade following its emergence in 2013, chikungunya virus (CHIKV) continues to spread and cause epidemics across the region. To date, 3.7 million suspected and laboratory-confirmed chikungunya cases have been reported in 50 countries or territories in the Americas. Here, we outline the current status and epidemiological aspects of chikungunya in the Americas and discuss prospects for future research and public health strategies to combat CHIKV in the region.
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2667-193X
    ISSN (online) 2667-193X
    DOI 10.1016/j.lana.2023.100673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Is Response to a Pre-implant Diagnostic Peripheral Nerve Block Associated With Efficacy After Peripheral Nerve Stimulation Implantation? A Ten-Year Enterprise-Wide Analysis.

    Hoffmann, Chelsey M / Butler, Casey S / Pingree, Matthew J / Moeschler, Susan M / Mauck, William D / D'Souza, Ryan S

    Neuromodulation : journal of the International Neuromodulation Society

    2023  

    Abstract: Objectives: This study aimed to assess whether patient response to targeted diagnostic peripheral nerve block before peripheral nerve stimulator (PNS) device implantation is associated with efficacy after PNS implantation.: Materials and methods: The ...

    Abstract Objectives: This study aimed to assess whether patient response to targeted diagnostic peripheral nerve block before peripheral nerve stimulator (PNS) device implantation is associated with efficacy after PNS implantation.
    Materials and methods: The electronic medical records from the Mayo Clinic Enterprise (three quarternary care medical centers and additional satellite medical centers) were reviewed to identify patients who underwent PNS implantation between January 2014 and January 2023. A primary outcome of interest was to assess whether administration of a preimplant diagnostic peripheral nerve block predicted pain relief at three months and six months after temporary and permanent PNS implantation. Another primary outcome was to investigate whether there was an association between the pain relief from a preimplant diagnostic peripheral nerve block and pain relief after three and six months after temporary or permanent PNS therapy. Linear regression analysis was conducted for outcomes of interest.
    Results: Of 193 eligible patients who underwent PNS therapy, a total of 173 patients were included in the final analysis and were stratified into either the temporary PNS cohort (n = 112) or the permanent PNS cohort (n = 61). Overall, 77.5% of all patients (134/173) underwent a preimplant diagnostic peripheral nerve block and reported a mean percentage relief of 70.1 ± 27.0 from the diagnostic block. Of patients in the temporary PNS cohort, there was no difference in postimplant percentage pain relief between patients who received a diagnostic block (n = 93) and control patients (n = 19) at three months (35.4 ± 36.0 vs 49.8 ± 36.1, respectively; β -14.45, 95% CI -32.98 to 4.07, p = 0.125) or at six months (23.3 ± 30.8 vs 45.7 ± 40.0, respectively; β -22.39, 95% CI -46.86 to 2.08, p = 0.072). Of patients in the permanent PNS cohort, there was no difference in postimplant percentage pain relief between patients who received a diagnostic block (n = 41) and control patients (n = 20) at three months (42.4 ± 34.3 vs 43.2 ± 42.4, respectively; β -0.79, 95% CI -23.56 to 21.99, p = 0.945) or at six months (44.3 ± 35.0 vs 38.8 ± 40.9, respectively; β 5.42, 95% CI -20.04 to 30.88, p = 0.669). Pain relief from preimplant diagnostic blocks was associated with postimplant pain relief from temporary PNS at three months (β 0.33, 95% CI 0.04-0.61, p = 0.025). However, pain relief from preimplant diagnostic blocks did not predict postimplant pain relief from temporary PNS at six months, or permanent PNS at three months and six months.
    Conclusions: Administration of a diagnostic block is not associated with superior pain relief at three or six months after PNS implantation to that of an approach without diagnostic block. Pain relief from a diagnostic block may potentially predict short-term pain relief after temporary PNS therapy, although future prospective studies are warranted to evaluate the prognostic utility of diagnostic blocks.
    Language English
    Publishing date 2023-11-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1016/j.neurom.2023.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prognostic risk factors of buccal squamous cell carcinoma: A case-control study.

    Callander, Jacquelyn K / Souza, Spenser S / Eltawil, Yasmin / El-Sayed, Ivan H / George, Jonathan R / Ha, Patrick / Ryan, William R / Xu, Mary Jue / Heaton, Chase M

    Head & neck

    2024  

    Abstract: Objectives: To describe the clinicopathologic presentation of buccal squamous cell carcinoma and identify risks factors for recurrence and overall survival.: Methods: This is a retrospective case-control study of patients with oral cavity squamous ... ...

    Abstract Objectives: To describe the clinicopathologic presentation of buccal squamous cell carcinoma and identify risks factors for recurrence and overall survival.
    Methods: This is a retrospective case-control study of patients with oral cavity squamous cell carcinoma (OCSCC) treated at a single tertiary care center between 2010 and 2022. All patients with buccal subsite OCSCC treated during this time frame were included and paired with a randomly selected age and gender matched patient with non-buccal OCSCC. Relevant data was collected via chart review.
    Results: Seventy-seven patients with buccal SCC were matched with 77 non-buccal OCSCC controls. The median follow-up time was 27 months (IQR 14-61). Median age was 67 years (IQR 57-75) and 53% of the cohort was female. Twenty (26%) buccal SCC patients experienced a recurrence versus 19 (25%) in the controls. Age ≥65-years-old increased odds of all-cause mortality in the buccal SCC group, but not in the control group. Perineural invasion and positive margins increased odds of recurrence in the buccal group only. Overall survival and progression-free survival did not differ between the groups, despite a greater number of T2 buccal tumors and T1 non-buccal tumors.
    Conclusions: Buccal SCC presents at a higher T stage than other oral cavity SCC subsite and may exhibit variance in the pathologic risk factors that predict poor outcomes versus non-buccal OCSCC. Despite these relatively minor differences, however, oncologic outcomes between these groups were similar.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018-2021.

    Forato, Julia / Meira, Cássio A / Claro, Ingra M / Amorim, Mariene R / de Souza, Gabriela F / Muraro, Stefanie P / Toledo-Teixeira, Daniel A / Dias, Miguel F / Meneses, Cátia A R / Angerami, Rodrigo N / Lalwani, Pritesh / Weaver, Scott C / Sabino, Ester C / Faria, Nuno R / de Souza, William M / Granja, Fabiana / Proenca-Modena, José Luiz

    Emerging infectious diseases

    2024  Volume 30, Issue 5, Page(s) 1013–1016

    Abstract: We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018-2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D. Improved surveillance is needed to better ... ...

    Abstract We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018-2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D. Improved surveillance is needed to better determine the burden of MAYV in the Amazon Region.
    MeSH term(s) Humans ; Brazil/epidemiology ; Molecular Epidemiology ; Fever/virology ; Fever/epidemiology ; Male ; Phylogeny ; Adult ; Alphavirus/genetics ; Alphavirus/classification ; Female ; Genotype ; Child ; Middle Aged ; Adolescent ; Child, Preschool ; History, 21st Century ; Young Adult ; Aged ; Arenaviridae Infections/epidemiology ; Arenaviridae Infections/virology ; Alphavirus Infections/epidemiology ; Alphavirus Infections/virology ; Infant
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Research Support, Non-U.S. Gov't ; Journal Article ; Historical Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid3005.231406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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