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  1. Book: Khartoum North and Omdurman ; by Mahmoud Kamil El-Rayes, Mohamed A. Osman, El Faith M. Ali

    El-Rayes, Mahmoud Kamil / Ali, El Faith M / Osman, Mohamed A

    (Building Research Digest, National Building Research Station, University of Khartoum ; 10 ; Soil profiles and analysis in Sudan ; ; 2)

    1973  

    Series title Building Research Digest, National Building Research Station, University of Khartoum ; 10
    Soil profiles and analysis in Sudan
    ; 2
    Keywords Stadtbau ; Stadtraum ; Sudan ; Khartoum North ; Omdurman
    Size 10, 19 S
    Publishing place Khartoum
    Document type Book
    Database ECONomics Information System

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  2. Article ; Online: Comparing specific capacitance in rice husk-derived activated carbon through phosphoric acid and potassium hydroxide activation order variations.

    Barakat, Nasser A M / Mahmoud, Mohamed S / Moustafa, Hager M

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1460

    Abstract: This manuscript investigates the influence of the chemical activation step order and process parameters on the specific capacitance of activated carbon derived from rice husk. The chemical activation was performed either before or after the carbonization ...

    Abstract This manuscript investigates the influence of the chemical activation step order and process parameters on the specific capacitance of activated carbon derived from rice husk. The chemical activation was performed either before or after the carbonization step, using phosphoric acid (H
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49675-0
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  3. Article: Protective Effects of Propolis and Chitosan Nanoparticles against Ibuprofen-Induced Hepatotoxicity in Albino Rats.

    AlKandari, Fajer M / Mohamed, Hussein S / Ahmed, Sayed A / Mahmoud, Basant / Mahmoud, Asmaa M

    Diseases (Basel, Switzerland)

    2024  Volume 12, Issue 3

    Abstract: Post-marketing hepatotoxicity findings are more common or occur much later. NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen are consumed in large quantities around the world. NSAIDs have a low incidence of hepatotoxicity but their wide use ... ...

    Abstract Post-marketing hepatotoxicity findings are more common or occur much later. NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen are consumed in large quantities around the world. NSAIDs have a low incidence of hepatotoxicity but their wide use makes them a major contributor to drug-induced liver injury. Hepatitis is linked to systemic oxidative stress which results in cellular necrosis and fibrosis, as well as tissue lipoprotein peroxidation and glutathione depletion. Given the lack of safe and effective anti-hepatitis drugs in medicine today, natural substances appear to be a promising and safe alternative. Propolis and chitosan are considered natural substances that have a protective effect on the hepatocytes. The purpose of this study was to validate the protective effect of propolis/chitosan nanoparticle extracts on ibuprofen-induced hepatotoxicity. Thirty (30) albino rats were used for the experiment. Animals were exposed to ibuprofen (400 mg/kg body weight/day) for 4 weeks (7 days/week) followed by treatment with propolis (200 mg/kg body weight/day) and chitosan extract (200 mg/kg body weight/day) separately and also in combination for consecutive 4 weeks. This study revealed a significant increase in serum transaminases, alkaline phosphatase, albumin, and total bilirubin in serum, as well as an increase in lipid peroxidation (MDA) and nitric oxide (NO). Furthermore, GSH, GST, and SOD decreased significantly in the group that was exposed to ibuprofen. Furthermore, there was a significant increase in pro-inflammatory parameters such as IL-1β and NF-ĸB, as well as low levels of anti-inflammatory parameters such as IL-6 and BCl-2. These alterations were improved by propolis and chitosan extracts, which was further confirmed in experimental animals. This study demonstrated that propolis and chitosan nanoparticle extracts have the potential to protect against hepatotoxicity induced by ibuprofen, due to their ability to regulate anti-inflammatory and anti-oxidative defense activities.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720869-2
    ISSN 2079-9721
    ISSN 2079-9721
    DOI 10.3390/diseases12030049
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  4. Article: Use of K-Y Jelly on Throat Packs for Postoperative Sore Throat after Nasal Surgery: A Randomized Controlled Trial.

    Elgarhy, Ahmed Mahmoud M M / Abdelhameed, Saeed Mostafa / Yahia, Othman Saadeldien / Ibrahim, Wael Mohamed Elmahdy / Ewieda, Tamer Mohamed Ahmed / Elsayed, Mahmoud M / Abdel-Aziz, Marwa M / Elshehawy, Naglaa A / Abdelkader, Hussein Magdy / Al Boghdady, Mahmoud Hamdy / Abbas, Ayman Yehia

    International archives of otorhinolaryngology

    2024  Volume 28, Issue 2, Page(s) e314–e318

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2024-01-04
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2578584-9
    ISSN 1809-4864 ; 1809-9777
    ISSN (online) 1809-4864
    ISSN 1809-9777
    DOI 10.1055/s-0043-1776724
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  5. Article ; Online: Cationic cellulose nanocrystals as sustainable green material for multi biological applications via ξ potential.

    Mahmoud, Sara Mohamed / Ali, Safwat Hassan / Omar, Mohamed M A

    Journal of biomaterials science. Polymer edition

    2023  Volume 34, Issue 11, Page(s) 1618–1642

    Abstract: The present study aims to disclose the activity of cationic cellulose nanocrystals (CNCs) as a promising multifunctional green nanomaterial with applications in biological aspects. The basic reason behind multifunctional behavior is zeta potential and ... ...

    Abstract The present study aims to disclose the activity of cationic cellulose nanocrystals (CNCs) as a promising multifunctional green nanomaterial with applications in biological aspects. The basic reason behind multifunctional behavior is zeta potential and size distribution of nano biopolymers; exhibit a remarkable physical and biological activity compared to normal molecules.The preliminary characterized studied using absorption spectral analysis showed strong absorption peak indicating that spectrum curves can be screen by UV spectra at wavelength range 200-400nm. Ultrastructural studies (SEM-EDS and TEM), manifest that CNCs are elliptical particles in shape. Also, TEM show CNCs are the ideal illustration of zero-dimensional (0-D) NPs, less than 5.1 nm in diameter with Cationic charge and similar results in size distribution by TEM. Nonetheless, developed as antioxidant activity IC
    MeSH term(s) Humans ; Cellulose/pharmacology ; Cellulose/chemistry ; Caco-2 Cells ; Nanoparticles/chemistry ; Hydrophobic and Hydrophilic Interactions ; Apoptosis
    Chemical Substances Cellulose (9004-34-6)
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1014190-x
    ISSN 1568-5624 ; 1568-5616 ; 0920-5063
    ISSN (online) 1568-5624 ; 1568-5616
    ISSN 0920-5063
    DOI 10.1080/09205063.2023.2177474
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2931: Show issues Location:
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  6. Article ; Online: Involvement of CircRNAs in regulating The "New Generation of Cancer Hallmarks": A Special Depiction on Hepatocellular Carcinoma.

    Dawoud, A / Elmasri, R A / Mohamed, A H / Mahmoud, A / Rostom, M M / Youness, R A

    Critical reviews in oncology/hematology

    2024  Volume 196, Page(s) 104312

    Abstract: The concept of 'Hallmarks of Cancer' is an approach of reducing the enormous complexity of cancer to a set of guiding principles. As the underlying mechanism of cancer are portrayed, we find that we gain insight and additional aspects of the disease ... ...

    Abstract The concept of 'Hallmarks of Cancer' is an approach of reducing the enormous complexity of cancer to a set of guiding principles. As the underlying mechanism of cancer are portrayed, we find that we gain insight and additional aspects of the disease arise. The understanding of the tumor microenvironment (TME) brought a new dimension and led to the discovery of novel hallmarks such as senescent cells, non-mutational epigenetic reprogramming, polymorphic microbiomes and unlocked phenotypic plasticity. Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across all species. Recent studies on the circRNAs have highlighted their crucial function in regulating the formation of human malignancies through a range of biological processes. The primary goal of this review is to clarify the role of circRNAs in the most common form of liver cancer, hepatocellular carcinoma (HCC). This review also addressed the topic of how circRNAs affect HCC hallmarks, including the new generation hallmarks. Finally, the enormous applications that these rapidly expanding ncRNA molecules serve in the functional and molecular development of effective HCC diagnostic biomarkers and therapeutic targets.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; RNA, Circular/genetics ; Liver Neoplasms/diagnosis ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; RNA/genetics ; Tumor Microenvironment/genetics
    Chemical Substances RNA, Circular ; RNA (63231-63-0)
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 605680-5
    ISSN 1879-0461 ; 0737-9587 ; 1040-8428
    ISSN (online) 1879-0461
    ISSN 0737-9587 ; 1040-8428
    DOI 10.1016/j.critrevonc.2024.104312
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1931: Show issues Location:
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  7. Article ; Online: Green UPLC method for estimation of ciprofloxacin, diclofenac sodium, and ibuprofen with application to pharmacokinetic study of human samples.

    Ahmed-Anwar, Alaa A / Mohamed, Mahmoud A / Farghali, Ahmed A / Mahmoud, Rehab / Hassouna, Mohamed E M

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 17613

    Abstract: Investigation of a unique and fast method for the determination and separation of a mixture of three drugs viz., ciprofloxacin (CIP), Ibuprofen (IBU), and diclofenac sodium (DIC) in actual samples of human plasma. Also, the technique was used to look at ... ...

    Abstract Investigation of a unique and fast method for the determination and separation of a mixture of three drugs viz., ciprofloxacin (CIP), Ibuprofen (IBU), and diclofenac sodium (DIC) in actual samples of human plasma. Also, the technique was used to look at their pharmacokinetics study. Hydrocortisone was chosen as the internal standard (IS). The drugs were chromatographically separated using an Acquity ultra-performance liquid chromatography UPLC ® BEH C18 1.7 µm (2.1 × 150 mm) column with a mobile phase composed of acetonitrile: water (65:35, v/v) adjusted to pH 3 with diluted acetic acid. Plasma proteins were precipitated with acetonitrile. The separated drugs ranged from 0.3 to 10, 0.2-11, and 1-25 µg/mL for CIP, IBU, and DIC, respectively. Calibration curves were discovered to achieve linearity with acceptable correlation coefficients (0.99%). Examination of quality assurance samples showed exceptional precision and accuracy. Following the successful application of this improved technique to plasma samples, the pharmacokinetic characteristics of each selected drug were evaluated using (UPLC) with UV detection at 210 nm. Two green metrics were applied, the Analytical Eco-scale and the Analytical GREEnness Calculator (AGREE). Separation was achieved in only 4-min analysis time. The method's validation agreed with the requirements of the FDA, and the results were sufficient.
    MeSH term(s) Humans ; Diclofenac ; Ibuprofen ; Chromatography, High Pressure Liquid/methods ; Ciprofloxacin ; Tandem Mass Spectrometry/methods ; Reproducibility of Results ; Acetonitriles
    Chemical Substances Diclofenac (144O8QL0L1) ; Ibuprofen (WK2XYI10QM) ; Ciprofloxacin (5E8K9I0O4U) ; Acetonitriles
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44846-5
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  8. Article ; Online: Lichen planus follicularis tumidus in a patient with a history of hepatitis C.

    Hassab-El-Naby, Hussein M M / Rageh, Mahmoud A / El-Khalawany, Mohamed

    Journal of cutaneous pathology

    2024  

    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14634
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1043: Show issues Location:
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  9. Article ; Online: Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived

    Mohamed, Manar Magdy Mahmoud / Abboud, Maria Mahmoud / Maleckis, Matiss / Souza, Luciano D O / Moreira, José M A / Gotfredsen, Charlotte H / Weber, Tilmann / Ding, Ling

    Journal of natural products

    2024  Volume 87, Issue 4, Page(s) 1075–1083

    Abstract: Cinnamoyl moiety containing nonribosomal peptides represented by pepticinnamin E are a growing family of natural products isolated from ... ...

    Abstract Cinnamoyl moiety containing nonribosomal peptides represented by pepticinnamin E are a growing family of natural products isolated from different
    MeSH term(s) Streptomyces/chemistry ; Soil Microbiology ; Molecular Structure ; Humans ; Multigene Family ; Peptides/chemistry ; Peptides/pharmacology ; Peptides/isolation & purification ; Cell Line, Tumor
    Chemical Substances Peptides
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.4c00029
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    Zs.A 1144: Show issues Location:
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  10. Article ; Online: Revealing the role of high-intensity interval training combined with inspiratory muscle training on atrial fibrillation associated with chronic heart failure: is there a shift toward anti-remodelling adaptation?

    Mehani, Sherin H M / Helmy, Zeinab M / Abdelhalim, Walaa A / Mohamed, Mahmoud I

    European journal of preventive cardiology

    2024  

    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwae125
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    Zs.A 4686: Show issues Location:
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