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  1. Article ; Online: Melanoidins Formed by Heterocyclic Maillard Reaction Intermediates via Aldol Reaction and Michael Addition.

    Kanzler, Clemens / Haase, Paul T

    Journal of agricultural and food chemistry

    2019  Volume 68, Issue 1, Page(s) 332–339

    Abstract: Thermal treatment of food leads to the formation of melanoidins by reactions of carbohydrates with free amino acids or proteins in the late stage of Maillard reaction. The aim of this study was the identification of reaction mechanisms responsible for ... ...

    Abstract Thermal treatment of food leads to the formation of melanoidins by reactions of carbohydrates with free amino acids or proteins in the late stage of Maillard reaction. The aim of this study was the identification of reaction mechanisms responsible for the formation of melanoidins involving active methylenes with the heterocyclic structure and the structural characterization of the resulting products. For this purpose, norfuraneol was incubated with the aldehydes pyrrole-2-aldehyde or furfural at 125 °C. With the help of high-resolution mass spectrometry, the structural composition of oligomers of up to fifteen C
    MeSH term(s) Aldehydes/chemistry ; Furaldehyde/chemistry ; Furans/chemistry ; Heterocyclic Compounds/chemistry ; Maillard Reaction ; Molecular Structure ; Oxidation-Reduction ; Polymers/chemistry
    Chemical Substances Aldehydes ; Furans ; Heterocyclic Compounds ; Polymers ; melanoidin polymers ; Furaldehyde (DJ1HGI319P) ; 4-hydroxy-5-methyl-3(2H)-furanone (MTB57102LQ)
    Language English
    Publishing date 2019-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.9b06258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Melanoidins Formed by Heterocyclic Maillard Reaction Intermediates via Aldol Reaction and Michael Addition

    Kanzler, Clemens / Haase, Paul T

    Journal of agricultural and food chemistry. 2019 Dec. 07, v. 68, no. 1

    2019  

    Abstract: ... for the first time. Aldol and Michael reactions could be identified as crucial steps for the formation of new C ...

    Abstract Thermal treatment of food leads to the formation of melanoidins by reactions of carbohydrates with free amino acids or proteins in the late stage of Maillard reaction. The aim of this study was the identification of reaction mechanisms responsible for the formation of melanoidins involving active methylenes with the heterocyclic structure and the structural characterization of the resulting products. For this purpose, norfuraneol was incubated with the aldehydes pyrrole-2-aldehyde or furfural at 125 °C. With the help of high-resolution mass spectrometry, the structural composition of oligomers of up to fifteen C5-units could be described for the first time. Aldol and Michael reactions could be identified as crucial steps for the formation of new C–C-bonds. With increasing heating time, the elimination of water from the products was facilitated, and oxidation reactions of integrated reductone structures lead to the expansion of conjugated double-bond systems responsible for the color formation of the samples.
    Keywords Maillard reaction ; carbohydrates ; chemical bonding ; color ; free amino acids ; furfural ; heat ; heat treatment ; mass spectrometry ; melanoidins ; oxidation ; proteins ; reaction mechanisms
    Language English
    Dates of publication 2019-1207
    Size p. 332-339.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.9b06258
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 1185: Show issues

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  3. Book: Organmonitoring mit Biomarkern und Laborwerten auf einen Blick

    Haase, Michael

    (UNI-MED Science)

    2014  

    Author's details [Michael Haase ...]
    Series title UNI-MED Science
    Language German
    Size 69 S. : graph. Darst.
    Edition 1. Aufl.
    Publisher UNI-MED-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018660304
    ISBN 978-3-8374-1473-8 ; 3-8374-1473-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 2081 available for loan (reading room) Lesesaal EG

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  4. Book: Akute Nierenschädigung

    Haase, Michael / Haase-Fielitz, Anja

    Alarmsystem, Patientenausweis, Behandlungspfade

    2015  

    Author's details Michael Haase ; Anja Haase-Fielitz (Hrsg.)
    Keywords Nierenversagen
    Subject Akute Niereninsuffizienz ; Akutes Nierenversagen ; Akute Nierenschädigung
    Language German
    Size XIV, 152 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018675277
    ISBN 978-3-642-45079-2 ; 3-642-45079-2 ; 9783642450808 ; 3642450806
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 2279 available for loan (reading room) Lesesaal EG

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  5. Book: Managing renal injury in the elderly patient

    Haase, Michael / Haase-Fielitz, Anja

    2014  

    Author's details Michael HAase ; Anja Haase-Fielitz ed
    Keywords Alter ; Nierenversagen
    Subject Akute Niereninsuffizienz ; Akutes Nierenversagen ; Akute Nierenschädigung ; Alter Mensch ; Betagter ; Senioren ; Senior
    Language English
    Size V, 100 S. :Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017905637
    ISBN 978-3-642-39946-6 ; 3-642-39946-0 ; 9783642399473 ; 3642399479
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 3753 available for loan (reading room) Lesesaal EG

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  6. Book ; Thesis: Poly (ADP-Ribose) Polymerasen 1 und 2 in der Pathogenese des chronischen pulmonalen Strahlenschadens

    Mayer, Felicitas / Haase, Michael / Lee-Kirsch, Min Ae

    2020  

    Institution Klinik und Poliklinik für Kinderchirurgie
    Author's details von Felicitas Mayer geboren in Dresden ; Klinik und Poliklinik für Kinderchirurgie [Dresden]
    Language German
    Size VIII, 139 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2021
    HBZ-ID HT021210675
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 E 58 order for loan Magazin

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  7. Book ; Thesis: Der St. Petersburger Apotheker Friedrich Karl Flemming (1812 - 1894) als Förderer der Homöopathie in Russland

    Haase, Michael

    2007  

    Title variant Der Sankt Petersburger Apotheker Friedrich Karl Flemming (1812 - 1894) als Förderer der Homöopathie in Russland
    Author's details eingereicht von Michael Haase
    Subject code 615.1
    Language German
    Size 111 Bl., Ill., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leipzig, Univ., Diss., 2007
    HBZ-ID HT015300384
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 E 1919 order for loan Magazin

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  8. Book: Michael Praetorius Creutzbergensis

    Gudewill, Kurt / Haase, Hans

    1571(?) - 1621 ; zwei Beiträge zu seinem und seiner Kapelle Jubiläumsjahr

    1971  

    Author's details von Kurt Gudewill und Hans Haase
    Language German
    Size 56 S, Ill, 8°
    Publisher Möseler
    Publishing place Wolfenbüttel u.a.
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Thesis: Klinische Sicherheit und immunmodulatorische Kapazität der großporigen Hämofiltration bei Patienten mit einem septischen multiplen Organversagen

    Haase, Michael

    2004  

    Author's details von Michael Haase
    Language German
    Size 104 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diss., 2004
    HBZ-ID HT014388561
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 MB 1008 order for loan Magazin

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  10. Article: Care Bundle for Acute Kidney Injury in Cardiac Patients: A Cluster-Randomized Trial.

    Iwers, Ragna / Sliziuk, Veronika / Haase, Michael / Barabasch, Sophie / Zänker, Michael / Butter, Christian / Haase-Fielitz, Anja

    Journal of clinical medicine

    2023  Volume 12, Issue 19

    Abstract: Detection and timely intervention of acute kidney injury (AKI) is a major challenge worldwide. Electronic alerts for AKI may improve process- and patient-related endpoints. The present study evaluated the efficacy of an AKI electronic alert system and ... ...

    Abstract Detection and timely intervention of acute kidney injury (AKI) is a major challenge worldwide. Electronic alerts for AKI may improve process- and patient-related endpoints. The present study evaluated the efficacy of an AKI electronic alert system and care bundle. This is a two-arm, prospective, cluster-randomized, controlled trial enrolling patients with AKI (KDIGO criteria) and cardiac diseases. Patients were randomly assigned to a routine care group or intervention group (DRKS-IDDRKS00017751). Two hundred patients (age 79 years, 46% female) were enrolled, with 100 patients in each group. The primary endpoint did not differ between patients in the routine care group 0.5 (-7.6-10.8) mL/min/1.73 m
    Language English
    Publishing date 2023-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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