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  1. Article ; Online: miRNA-mRNA associations with inosine monophosphate specific deposition in the muscle of Jingyuan chicken.

    Yu, B / Liu, J / Cai, Z / Mu, T / Gu, Y / Xin, G / Zhang, J

    British poultry science

    2022  , Page(s) 1–12

    Abstract: ... content in Jingyuan chicken. The differential miRNA-mRNAs were screened out and correlation analysis ...

    Abstract 1. Inosine monophosphate (IMP), is an essential component for meat flavour and microRNAs (miRNAs) play a vital role in its post-transcriptional regulation. However, the mechanism of how miRNA expression affects muscle-specific IMP deposition is unclear.2. The following study performed transcriptome sequencing and bioinformatics analysis of breast and leg muscle, which have significantly different IMP content in Jingyuan chicken. The differential miRNA-mRNAs were screened out and correlation analysis with IMP content was performed.3. A total of 39 differentially expressed miRNAs (DE miRNAs) and 666 differentially expressed mRNAs (DE mRNAs) were identified between breast muscles and leg muscles. Using miRNA-mRNA integrated analysis, 29 miRNA-target gene pairs were obtained, composed of 13 DE miRNAs and 28 DE mRNAs. Next, purine metabolism, glycolysis/gluconeogenesis, pyruvate metabolism and the biosynthesis of amino acid pathways as necessary for muscle IMP-specific deposition were identified. The differentially expressed gene
    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 956653-3
    ISSN 1466-1799 ; 0007-1668
    ISSN (online) 1466-1799
    ISSN 0007-1668
    DOI 10.1080/00071668.2022.2106777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 928: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: miRNA-mRNA associations with inosine monophosphate specific deposition in the muscle of Jingyuan chicken

    Yu, B. / Liu, J. / Cai, Z. / Mu, T. / Gu, Y. / Xin, G. / Zhang, J.

    British Poultry Science. 2022 Nov. 02, v. 63, no. 6 p.821-832

    2022  

    Abstract: ... content in Jingyuan chicken. The differential miRNA-mRNAs were screened out and correlation analysis ... explores the functional mechanism of IMP-specific deposition in Jingyuan chicken muscles at the miRNA and ...

    Abstract 1. Inosine monophosphate (IMP), is an essential component for meat flavour and microRNAs (miRNAs) play a vital role in its post-transcriptional regulation. However, the mechanism of how miRNA expression affects muscle-specific IMP deposition is unclear. 2. The following study performed transcriptome sequencing and bioinformatics analysis of breast and leg muscle, which have significantly different IMP content in Jingyuan chicken. The differential miRNA-mRNAs were screened out and correlation analysis with IMP content was performed. 3. A total of 39 differentially expressed miRNAs (DE miRNAs) and 666 differentially expressed mRNAs (DE mRNAs) were identified between breast muscles and leg muscles. Using miRNA-mRNA integrated analysis, 29 miRNA-target gene pairs were obtained, composed of 13 DE miRNAs and 28 DE mRNAs. Next, purine metabolism, glycolysis/gluconeogenesis, pyruvate metabolism and the biosynthesis of amino acid pathways as necessary for muscle IMP-specific deposition were identified. The differentially expressed gene PKM2, which was significantly enriched in all four pathways, is involved in IMP anabolism in the form of energy metabolism and enzyme activity regulation. The correlation analysis suggested that the gga-miR-107-3p-KLHDC2 negative interaction may be a key regulator in IMP deposition. 4. This study explores the functional mechanism of IMP-specific deposition in Jingyuan chicken muscles at the miRNA and mRNA levels and highlights multiple candidate miRNAs and mRNAs for molecular-assisted breeding.
    Keywords amino acids ; anabolism ; bioinformatics ; biosynthesis ; breasts ; chickens ; energy metabolism ; enzyme activity ; flavor ; gene expression regulation ; genes ; gluconeogenesis ; glycolysis ; inosine monophosphate ; meat ; microRNA ; muscles ; pyruvic acid ; transcriptome ; Jingyuan chicken ; miRNA ; mRNA ; inosine monophosphate (IMP) ; miRNA-mRNA association analysis
    Language English
    Dates of publication 2022-1102
    Size p. 821-832.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 956653-3
    ISSN 1466-1799 ; 0007-1668
    ISSN (online) 1466-1799
    ISSN 0007-1668
    DOI 10.1080/00071668.2022.2106777
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 1354: Show issues

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  3. Article ; Online: Uncovering Rare Coding Variants in IgA Nephropathy.

    Liu, Jian / Xie, Jingyuan

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 11, Page(s) 1769–1771

    MeSH term(s) Humans ; Glomerulonephritis, IGA/genetics ; Genetic Predisposition to Disease ; Immunoglobulin A
    Chemical Substances Immunoglobulin A
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3344: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: First Report of Southern Blight Caused by

    Huang, Binbin / Huang, Jun / Guo, Zhaohui / Zheng, Jingyuan / Liu, Qingshu

    Plant disease

    2023  

    Abstract: Pepper( ...

    Abstract Pepper(
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-03-23-0462-PDN
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2043: Show issues

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  5. Article: Hierarchical Nanoheterostructure of HFIP-Grafted α-Fe

    Wang, Xuechun / Liu, Jingyuan / Li, Rumin / Yu, Jing / Liu, Qi / Zhu, Jiahui / Liu, Peili

    Nanomaterials (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: New and efficient sensors of nerve agents are urgently demanded to prevent them from causing mass casualties in war or terrorist attacks. So, in this work, a novel hierarchical nanoheterostructure was synthesized via the direct growth of α- ... ...

    Abstract New and efficient sensors of nerve agents are urgently demanded to prevent them from causing mass casualties in war or terrorist attacks. So, in this work, a novel hierarchical nanoheterostructure was synthesized via the direct growth of α-Fe
    Language English
    Publishing date 2024-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14030305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Artificial intelligence in fracture detection with different image modalities and data types: A systematic review and meta-analysis.

    Jung, Jongyun / Dai, Jingyuan / Liu, Bowen / Wu, Qing

    PLOS digital health

    2024  Volume 3, Issue 1, Page(s) e0000438

    Abstract: Artificial Intelligence (AI), encompassing Machine Learning and Deep Learning, has increasingly been applied to fracture detection using diverse imaging modalities and data types. This systematic review and meta-analysis aimed to assess the efficacy of ... ...

    Abstract Artificial Intelligence (AI), encompassing Machine Learning and Deep Learning, has increasingly been applied to fracture detection using diverse imaging modalities and data types. This systematic review and meta-analysis aimed to assess the efficacy of AI in detecting fractures through various imaging modalities and data types (image, tabular, or both) and to synthesize the existing evidence related to AI-based fracture detection. Peer-reviewed studies developing and validating AI for fracture detection were identified through searches in multiple electronic databases without time limitations. A hierarchical meta-analysis model was used to calculate pooled sensitivity and specificity. A diagnostic accuracy quality assessment was performed to evaluate bias and applicability. Of the 66 eligible studies, 54 identified fractures using imaging-related data, nine using tabular data, and three using both. Vertebral fractures were the most common outcome (n = 20), followed by hip fractures (n = 18). Hip fractures exhibited the highest pooled sensitivity (92%; 95% CI: 87-96, p< 0.01) and specificity (90%; 95% CI: 85-93, p< 0.01). Pooled sensitivity and specificity using image data (92%; 95% CI: 90-94, p< 0.01; and 91%; 95% CI: 88-93, p < 0.01) were higher than those using tabular data (81%; 95% CI: 77-85, p< 0.01; and 83%; 95% CI: 76-88, p < 0.01), respectively. Radiographs demonstrated the highest pooled sensitivity (94%; 95% CI: 90-96, p < 0.01) and specificity (92%; 95% CI: 89-94, p< 0.01). Patient selection and reference standards were major concerns in assessing diagnostic accuracy for bias and applicability. AI displays high diagnostic accuracy for various fracture outcomes, indicating potential utility in healthcare systems for fracture diagnosis. However, enhanced transparency in reporting and adherence to standardized guidelines are necessary to improve the clinical applicability of AI. Review Registration: PROSPERO (CRD42021240359).
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3170
    ISSN (online) 2767-3170
    DOI 10.1371/journal.pdig.0000438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Identification, Expression and Evolutional Analysis of Two

    Wang, Yajun / Lin, Jingyuan / Li, Wenjin / Ji, Guangdong / Liu, Zhenhui

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 8

    Abstract: The mechanism of sex determination and differentiation in animals remains a central focus of reproductive and developmental biology research, and the regulation of sex differentiation in amphioxus remains poorly understood. Cytochrome P450 Family 19 ... ...

    Abstract The mechanism of sex determination and differentiation in animals remains a central focus of reproductive and developmental biology research, and the regulation of sex differentiation in amphioxus remains poorly understood. Cytochrome P450 Family 19 Subfamily A member 1 (
    Language English
    Publishing date 2024-04-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14081140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: LncRNA MALAT1 suppresses monocyte-endothelial cell interactions by targeting miR-30b-5p and enhancing ATG5-mediated autophagy.

    Gu, Xiaodong / Hou, Jingyuan / Rao, Jiawei / Weng, Ruiqiang / Liu, Sudong

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28882

    Abstract: Background: Monocyte-endothelial cell (EC) interactions are one of the earliest events in the development of atherosclerosis and play a crucial role in atherosclerotic plaque formation. Although attempts have been made to modulate this interaction, the ... ...

    Abstract Background: Monocyte-endothelial cell (EC) interactions are one of the earliest events in the development of atherosclerosis and play a crucial role in atherosclerotic plaque formation. Although attempts have been made to modulate this interaction, the underlying molecular signalling mechanisms remain unclear. This study aimed to investigate the role of long non-coding RNA MALAT1 in monocyte-EC interactions.
    Methods: The expression of MALAT1, ICAM-1, VCAM-1, P-selectin, CCL2 and CXCL1 was evaluated in ApoE
    Results: MALAT1 expression decreased in ApoE
    Conclusions: Our findings suggest that MALAT1 suppresses monocyte-EC interactions by targeting miR-30b-5p and enhancing ATG5-mediated endothelial autophagy. These data imply that MALAT1 may play a protective role at the early stages of the atherosclerotic process.
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Transcriptome and metabolite analyses indicated the underlying molecular responses of Asian ginseng (

    Xia, Jinglin / Liu, Ning / Han, Junyou / Sun, Jingyuan / Xu, Tianyi / Liu, Shouan

    Frontiers in plant science

    2023  Volume 14, Page(s) 1182685

    Abstract: ... Panax ... ...

    Abstract Panax ginseng
    Language English
    Publishing date 2023-07-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1182685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Graph Multi-Scale Permutation Entropy for Bearing Fault Diagnosis.

    Fan, Qingwen / Liu, Yuqi / Yang, Jingyuan / Zhang, Dingcheng

    Sensors (Basel, Switzerland)

    2023  Volume 24, Issue 1

    Abstract: Bearing faults are one kind of primary failure in rotatory machines. To avoid economic loss and casualties, it is important to diagnose bearing faults accurately. Vibration-based monitoring technology is widely used to detect bearing faults. Graph signal ...

    Abstract Bearing faults are one kind of primary failure in rotatory machines. To avoid economic loss and casualties, it is important to diagnose bearing faults accurately. Vibration-based monitoring technology is widely used to detect bearing faults. Graph signal processing methods promising for the extraction of the fault features of bearings. In this work, graph multi-scale permutation entropy (MPE
    Language English
    Publishing date 2023-12-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24010056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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