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  1. Book: Unmet needs in anticoagulant therapy: recent and ongoing trials with rivaroxaban

    Eikelboom, John W.

    (Canadian journal of cardiology ; [volume 33, supplement])

    2017  

    Author's details John W Eikelboom MBBS, FRCPC
    Series title Canadian journal of cardiology ; [volume 33, supplement]
    The Canadian journal of cardiology
    Collection The Canadian journal of cardiology
    Language English
    Size 51 Seiten
    Publisher Elsevier
    Publishing place Erscheinungsort nicht ermittelbar
    Publishing country Canada
    Document type Book
    HBZ-ID HT019494470
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 2150 -[33,Suppl.]- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Urinary thromboxane and risk of cardiovascular events: role of aspirin.

    Eikelboom, John W / Kruger, Paul C

    European heart journal

    2024  Volume 45, Issue 15, Page(s) 1368–1370

    MeSH term(s) Humans ; Thromboxanes ; Aspirin/adverse effects ; Thromboxane A2 ; Cardiovascular Diseases/prevention & control ; Thromboxane B2 ; Platelet Aggregation Inhibitors/adverse effects
    Chemical Substances Thromboxanes ; Aspirin (R16CO5Y76E) ; Thromboxane A2 (57576-52-0) ; Thromboxane B2 (54397-85-2) ; Platelet Aggregation Inhibitors
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehae003
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    Zs.A 1563: Show issues Location:
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    Zs.MO 640: Show issues

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  3. Article ; Online: Event Adjudication Is Unnecessary in Blinded Trials and May Be Detrimental.

    Eikelboom, John W / Yusuf, Salim

    JACC. Heart failure

    2023  Volume 11, Issue 4, Page(s) 422–424

    MeSH term(s) Humans ; Heart Failure ; Research Design ; Treatment Outcome
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.01.027
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  4. Article ; Online: Direct Oral Anticoagulants in the Very Elderly.

    Eikelboom, John W / Weitz, Jeffrey I

    Thrombosis and haemostasis

    2023  Volume 123, Issue 4, Page(s) 377–379

    MeSH term(s) Humans ; Aged ; Anticoagulants/adverse effects ; Warfarin/therapeutic use ; Administration, Oral ; Atrial Fibrillation/drug therapy
    Chemical Substances Anticoagulants ; Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2023-01-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/a-2021-8910
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  5. Article ; Online: P-Selectin de-ACTIVation in COVID-19: What Have We Learned?

    Bikdeli, Behnood / Eikelboom, John W

    Circulation

    2023  Volume 148, Issue 5, Page(s) 391–393

    MeSH term(s) Humans ; P-Selectin ; COVID-19 ; Antibodies, Monoclonal, Humanized ; Antibodies, Monoclonal/pharmacology
    Chemical Substances crizanlizumab (L7451S9126) ; P-Selectin ; Antibodies, Monoclonal, Humanized ; Antibodies, Monoclonal
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.123.065619
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  6. Article ; Online: In healthy older adults, low-dose aspirin increased incident anemia at a median 4.7 y.

    Carlin, Stephanie / Eikelboom, John W

    Annals of internal medicine

    2023  Volume 176, Issue 10, Page(s) JC115

    Abstract: Source citation: McQuilten ZK, Thao LT, Pasricha SR, et al. ...

    Abstract Source citation: McQuilten ZK, Thao LT, Pasricha SR, et al.
    MeSH term(s) Aged ; Humans ; Anemia/chemically induced ; Anemia/epidemiology ; Aspirin/adverse effects ; Health Status
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/J23-0075
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  7. Article ; Online: In DVT, oral DTIs and factor Xa inhibitors reduce major bleeding but not recurrent VTE vs. conventional anticoagulants.

    Benz, Alexander P / Eikelboom, John W

    Annals of internal medicine

    2023  Volume 176, Issue 8, Page(s) JC92

    Abstract: Source citation: Wang X, Ma Y, Hui X, et al. ...

    Abstract Source citation: Wang X, Ma Y, Hui X, et al.
    MeSH term(s) Humans ; Anticoagulants/adverse effects ; Factor Xa Inhibitors/therapeutic use ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/prevention & control ; Antithrombins/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Administration, Oral
    Chemical Substances Anticoagulants ; Factor Xa Inhibitors ; Antithrombins
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/J23-0053
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  8. Article ; Online: Warfarin faring better: vitamin K antagonists beat rivaroxaban and apixaban in the INVICTUS and PROACT Xa trials.

    Eikelboom, John W / Weitz, Jeffrey I

    Journal of thrombosis and haemostasis : JTH

    2023  Volume 21, Issue 11, Page(s) 3067–3071

    Abstract: Although guidelines give preference to direct oral anticoagulants (DOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF), DOACs are not recommended in those with rheumatic heart disease or ... ...

    Abstract Although guidelines give preference to direct oral anticoagulants (DOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF), DOACs are not recommended in those with rheumatic heart disease or mechanical heart valves. The results of the INVICTUS trial (Investigation of Rheumatic AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies), which compared rivaroxaban with a VKA in patients with rheumatic heart disease-associated AF, and the PROACT Xa trial (A Trial to Determine if Participants with an On-X Aortic Valve Can be Maintained Safely on Apixaban), which compared apixaban with warfarin in patients with an On-X valve in the aortic position, support the use of VKAs for these indications. In this paper, we review the results of these trials, provide perspective on why VKAs were superior to DOACs, and discuss future directions for anticoagulation in these disorders.
    MeSH term(s) Humans ; Warfarin/adverse effects ; Rivaroxaban/adverse effects ; Rheumatic Heart Disease/complications ; Rheumatic Heart Disease/drug therapy ; Anticoagulants/adverse effects ; Pyridones/therapeutic use ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/complications ; Vitamin K ; Administration, Oral ; Fibrinolytic Agents/therapeutic use ; Stroke/drug therapy ; Stroke/prevention & control ; Stroke/complications ; Dabigatran/therapeutic use
    Chemical Substances Warfarin (5Q7ZVV76EI) ; Rivaroxaban (9NDF7JZ4M3) ; apixaban (3Z9Y7UWC1J) ; Anticoagulants ; Pyridones ; Vitamin K (12001-79-5) ; Fibrinolytic Agents ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2023-07-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1016/j.jtha.2023.06.036
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    Zs.MO 295: Show issues

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  9. Article ; Online: Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and End-Stage Renal Disease: Lessons Learned.

    Benz, Alexander P / Eikelboom, John W

    Circulation

    2022  Volume 146, Issue 23, Page(s) 1746–1748

    MeSH term(s) Humans ; Warfarin/adverse effects ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/epidemiology ; Pyridones/adverse effects ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/drug therapy ; Anticoagulants/adverse effects ; Stroke ; Treatment Outcome
    Chemical Substances Warfarin (5Q7ZVV76EI) ; apixaban (3Z9Y7UWC1J) ; Pyridones ; Anticoagulants
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.122.061647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: What Is the Future of Factor XI Inhibitors?

    Weitz, Jeffrey I / Eikelboom, John W

    Circulation

    2022  Volume 146, Issue 25, Page(s) 1899–1902

    MeSH term(s) Humans ; Factor XI ; Anticoagulants/therapeutic use ; Atrial Fibrillation/drug therapy ; Administration, Oral ; Stroke/drug therapy ; Factor Xa Inhibitors/therapeutic use
    Chemical Substances Factor XI (9013-55-2) ; Anticoagulants ; Factor Xa Inhibitors
    Language English
    Publishing date 2022-12-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.122.061132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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