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  1. Book ; Thesis: Evaluierung endourologischer Werkzeuge zur Verbesserung der Diagnostik und Therapie von Harnleitertumoren

    Porsch, Markus

    von der Modellentwicklung zur möglichen klinischen Anwendung

    2017  

    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details vorgelegt von Dr. med. Markus Porsch
    Keywords Urothelkrebs
    Subject Urothelkarzinom
    Language German
    Size 6 ungezählte Blätter, 160 Blätter, Illustrationen, Diagramme
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universitiät Magdeburg, 2017
    HBZ-ID HT019453835
    Database Catalogue ZB MED Medicine, Health

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    2017 E 1584 order for loan Magazin

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  2. Book ; Thesis: Akutes Skrotum

    Neuwirth, Philipp / Porsch, Markus / Schlüter, Dirk

    Klinische Erfahrungen der urologischen Klinik der Universität Magdeburg

    2021  

    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details von Philipp Neuwirth ; Gutachter: PD Dr. Markus Porsch ; Prof. Dr. Dirk Schlüter
    Keywords Akuter Hoden
    Subject Akutes Skrotum
    Language German
    Size II-V, 6-103 Blätter, Illustrationen, Diagramme
    Publisher Otto-von-Guericke-Universität Magdeburg
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Magdeburg, 2021
    HBZ-ID HT021379028
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Audio / Video ; Thesis: Die Atemalkoholmessung als Monitoring zur Früherkennung und Therapie des TUR-Syndroms im Rahmen der transurethralen Elektroresektion der Prostata

    Porsch, Markus

    eine retrospektive Analyse klinischer und paraklinischer Parameter von Patienten der Klinik für Urologie der Medizinischen Fakultät der Otto-von-Guericke-Universität Magdeburg von 1989 bis 2004

    2007  

    Author's details vorgelegt von Maarkus Porsch
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Magdeburg, Univ., Diss., 2007
    HBZ-ID HT015628591
    Database Catalogue ZB MED Medicine, Health

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    2007 MO 1197 order for loan Magazin

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  4. Article: Fall 3. Gutes klinisches Ansprechen auf Radium-223

    Porsch, Markus

    Thieme case report

    2015  Volume 7, Issue 3, Page(s) 10

    Language German
    Document type Article
    ISSN 1611-7875
    Database Current Contents Medicine

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  5. Book ; Online ; Thesis: Die interdisziplinäre Sprechstunde für Prostatakrebs an der Charité Berlin

    Kushner, Julien Christian Verfasser] / Porsch, Markus [Gutachter] / [Schlomm, Thorsten [Gutachter]

    Betrachtung der Gründungsphase aus Sicht der Leitlinienrealität 2019/2020

    2020  

    Author's details Julien Christian Kushner ; Gutachter: Markus Porsch, Thorsten Schlomm
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Otto-von-Guericke-Universität
    Publishing place Magdeburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  6. Book ; Thesis: Modellierung von Schädigungsmechanismen zur Beurteilung der Lebensdauer von Verbundkonstruktionen aus Stahl und Beton

    Porsch, Markus

    (Schriftenreihe des Instituts für Konstruktiven Ingenieurbau, Fachbereich D, Abteilung Bauingenieurwesen ; 17)

    2010  

    Author's details Markus Porsch. Institut für Konstruktiven Ingenieurbau, Bergische Universität Wuppertal
    Series title Schriftenreihe des Instituts für Konstruktiven Ingenieurbau, Fachbereich D, Abteilung Bauingenieurwesen ; 17
    Language German
    Size Getr. Zählung, Ill., graph. Darst., 24 cm
    Publisher IKIB, Inst. für Konstruktiven Ingenieurbau, Bergische Univ. Wuppertal
    Publishing place Wuppertal
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Wuppertal, 2010
    ISBN 9783940795168 ; 394079516X
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article ; Online: Molecular margin status after radical prostatectomy using glutathione S-transferase P1 (GSTP1) promoter hypermethylation.

    Witt, Jörn H / Friedrich, Maria / Jandrig, Burkhard / Porsch, Markus / Baumunk, Daniel / Liehr, Uwe-B / Wendler, Johann J / Schostak, Martin

    BJU international

    2021  Volume 130, Issue 4, Page(s) 454–462

    Abstract: Objective: To assess the potential for molecular staging in biopsies of the prostatic fossa after radical prostatectomy (RP) by searching for occult tumour cells through analysis of glutathione S-transferase P1 (GSTP1) methylation status.: Patients ... ...

    Abstract Objective: To assess the potential for molecular staging in biopsies of the prostatic fossa after radical prostatectomy (RP) by searching for occult tumour cells through analysis of glutathione S-transferase P1 (GSTP1) methylation status.
    Patients and methods: We analysed 2446 biopsies: 2286 biopsies from a group of 254 patients with clinically organ-confined prostate cancer who underwent RP and 160 biopsies from a control group of 32 patients. After prostate gland excision, biopsies were obtained from defined areas of the prostatic fossa and bisected for histopathological and molecular genetics analyses. Results were related to clinicopathological data including tumour stage, lymph node status, resection status, tumour grading, initial PSA level, and biochemical recurrence.
    Results: In total, 34 patients (13.4%) had at least one core positive for the GSTP1 promoter hypermethylation, six of whom (17.6%) were characterised as having a clinically localised tumour stage (pT2, pN0) and 28 (82.4%) as an advanced tumour stage (≥pT3 and/or pN1). GSTP1 promoter hypermethylation significantly correlated with tumour stage (P < 0.001), International Society of Urological Pathology grading (P = 0.001), lymph node status (P < 0.001), surgical margin status (P < 0.001), and biochemical recurrence (P = 0.001). Furthermore, in 46 patients (18.1%) further analysis led to a down- or upgrading of conventional surgical margin status. Classical R-status (margins of the specimen) is significantly superior to histological sampling from the fossa (P = 0.006) but not to GSTP1 analysis from the fossa (P = 0.227).
    Conclusion: For the detection of residual tumour in the fossa after RP in order to better predict recurrence, molecular GSTP1 promoter hypermethylation has some value; however, the classical R-status (margins of the specimen) is simpler and more widely applicable with similar results.
    MeSH term(s) Glutathione S-Transferase pi/genetics ; Glutathione Transferase ; Humans ; Male ; Margins of Excision ; Neoplasm Recurrence, Local/pathology ; Prostate/pathology ; Prostate-Specific Antigen ; Prostatectomy/methods ; Prostatic Neoplasms/chemistry ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/surgery
    Chemical Substances GSTP1 protein, human (EC 2.5.1.18) ; Glutathione S-Transferase pi (EC 2.5.1.18) ; Glutathione Transferase (EC 2.5.1.18) ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2021-11-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.15618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui VI Zs.107: Show issues Location:
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  8. Article ; Online: RISK MANAGEMENT OF GERMAN FRUIT PRODUCERS

    Annkatrin PORSCH / Markus GANDORFER / Vera BITSCH

    Review of Agricultural and Applied Economics, Vol 21, Iss 1, Pp 10-

    2018  Volume 22

    Abstract: Horticultural farms in Germany face substantial business risks. However, fruit farms often struggle to implement appropriate risk management processes, and the risk management literature widely has ignored this farm type. The aim of the study was to ... ...

    Abstract Horticultural farms in Germany face substantial business risks. However, fruit farms often struggle to implement appropriate risk management processes, and the risk management literature widely has ignored this farm type. The aim of the study was to improve the assessment of risks by farmers and the choice of suitable risk management instruments. Therefore, a risk management process based on subjective probabilities and suitable for small and medium-sized farms was developed, considering the specific needs of family run businesses. An online survey was conducted to achieve a comprehensive view of the risk perception and risk management practices of German fruit producers. Price and production risks are the most relevant risk categories for fruit farmers. However, among single risk sources, those in the people risk category were seen as the most important. Results show significant interactions among risk categories and a significant correlation between loss experience and the rating of risk categories. The assumption that risk averse farmers generally rate risks higher than risk neutral or risk seeking farmers cannot be confirmed. Diversification seems to be the most important risk management instrument for many fruit producers, especially diversification of marketing channels, farm income, and production activities. Further research should focus on the apparent inconsistency between the satisfaction with instruments reported by farmers and the actual implementation of many of them (e.g., hail insurance and anti-hail net). Furthermore, there is a need for research, to develop decision models considering the interactions of risks and risk management instruments, loss experience and risk seeking attitudes.
    Keywords horticulture ; people risk ; risk management instruments ; subjective probabilities ; Agriculture ; S ; Agriculture (General) ; S1-972
    Language English
    Publishing date 2018-03-01T00:00:00Z
    Publisher Slovak University of Agriculture
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Die Empfehlungen der S2k-Leitlinie zur Diagnostik, Therapie und Metaphylaxe der Urolithiasis bilden einen sicheren Handlungskorridor für die ureterorenoskopische Steintherapie – Ergebnisse der BUSTER-Studie.

    Lebentrau, Steffen / May, Matthias / Ziegler, Heiko / Werthemann, Peter / Enzmann, Thomas / Schostak, Martin / Porsch, Markus

    Aktuelle Urologie

    2017  Volume 49, Issue 2, Page(s) 164–170

    Abstract: Background:  Given the high incidence, prevalence and rate of recurrence, urolithiasis stone treatment at a high stone-free rate should have a low complication rate. The German S2k guideline (GS2k-GL) for the diagnostic testing, therapy and metaphylaxis ...

    Title translation The recommendations of the S2k guideline for the diagnosis, therapy and metaphylaxis of urolithiasis provide a safe course of action for ureterorenoscopic stone treatment - results of the BUSTER study.
    Abstract Background:  Given the high incidence, prevalence and rate of recurrence, urolithiasis stone treatment at a high stone-free rate should have a low complication rate. The German S2k guideline (GS2k-GL) for the diagnostic testing, therapy and metaphylaxis of urolithiasis provides recommendations for the first and second choice for stone treatment, depending on stone location and size. Ureterorenoscopy (URS) is the treatment of first choice for most stones. URS is only the second option for renal stones > 20 mm and proximal ureteric stones ≤ 10 mm. The objective was to examine the impact of using URS as the stone treatment of first or second choice on the endpoints stone-free rate and severity of complications.
    Patients/methods:  The multicentric prospective observational study "Evaluation of ureteroroscopic stone treatment - results with regard to complications, quality of life and the stone-free rate" (BUSTER) standardised recorded perioperative data from 307 patients who had undergone ureterorenoscopic stone treatment from January to April 2015 at 14 German urological clinics. Treatment decisions were not affected by the study protocol.
    Results:  In the univariate analysis, the stone-free rate for ureteric stones was significantly higher when URS was the treatment of first choice (OR 2.21, 95 % CI 1.11 - 4.40, p = 0.027). After adjustment for age, BMI, ASA score, preoperative ureteral stenting, stone location and size, presence of multiple stones, experience of the surgeon, acute or elective URS and operating time, the application of URS as treatment of first choice had no significant effect on the stone-free rate (OR 2.048, 95 % CI 0.890 - 4.710, p = 0.092). After adjustment for stone location and size as well as ureteral stenting following URS, the application of URS as treatment of first choice had no significant influence on the severity of complications (OR 1.019, 95 % CI 0.347 to 2.993; p = 0.973).
    Conclusion:  On the basis of our data, URS proved to be a safe and effective stone treatment procedure regardless of the degree of guideline conformity. Although the stone-free rate was higher with URS as treatment of first choice, the results of URS as treatment of second choice were not significantly worse. The recommendations of the GS2k-GL offer a safe guide for ureterorenoscopic stone treatment. The tendency for higher stone-free rates in URS as a treatment of first choice should be examined in further studies.
    MeSH term(s) Adult ; Aged ; Female ; Humans ; Kidney Calculi ; Lithotripsy ; Male ; Middle Aged ; Practice Guidelines as Topic ; Treatment Outcome ; Ureteral Calculi ; Ureteroscopy/methods ; Urolithiasis/diagnosis ; Urolithiasis/therapy
    Language German
    Publishing date 2017-10-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124847-9
    ISSN 1438-8820 ; 0001-7868
    ISSN (online) 1438-8820
    ISSN 0001-7868
    DOI 10.1055/s-0043-116859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Leitfaden zur Nutzen-Kosten-Abschätzung umweltrelevanter Effekte in der Gesetzesfolgenabschätzung

    Porsch, Lucas / Genius, Wolf / Maibach, Markus / Preiss, Philipp / Sutter, Daniel

    (Texte / Umweltbundesamt ; 2015, 01)

    2015  

    Institution Deutschland / Umweltbundesamt
    Author's details von Lucas Porsch (Ecologic Institut gemeinnützige GmbH, Berlin), Daniel Sutter, Markus Maibach (INFRAS AG Forschung und Beratung, Zürich), Philipp Preiss, Wolf Müller (IER Universität Stuttgart, Stuttgart) ; im Auftrag des Umweltbundesamtes
    Series title Texte / Umweltbundesamt ; 2015, 01
    Keywords Umweltpolitik ; Wirkungsanalyse ; Kosten-Nutzen-Analyse ; Deutschland
    Language German
    Size 1 Online-Ressource (circa 93 Seiten), Illustrationen
    Publisher Umweltbundesamt
    Publishing place Dessau-Roßlau
    Document type Book ; Online
    Note Zusammenfassung in englischer Sprache
    Database ECONomics Information System

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