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  1. Article: Successful Three-Dimensional Mapping-Guided Sinus Node Modification for Drug-Refractory Inappropriate Sinus Tachycardia after Circumferential Pulmonary Vein Isolation.

    Liu, Hao-Tien / Wen, Ming-Shien / Chou, Chung-Chuan

    Acta Cardiologica Sinica

    2024  Volume 40, Issue 1, Page(s) 128–132

    Language English
    Publishing date 2024-01-18
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 1051394-2
    ISSN 1011-6842
    ISSN 1011-6842
    DOI 10.6515/ACS.202401_40(1).20231026A
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3059: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Reply to "Does the burden of premature ventricular contractions predict adverse fetal and neonatal outcomes among pregnant women without structural heart disease?"

    Chou, Chung-Chuan / Liu, Hao-Tien

    International journal of cardiology

    2023  Volume 387, Page(s) 131171

    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Pregnant Women ; Ventricular Premature Complexes/diagnosis ; Ventricular Premature Complexes/epidemiology ; Birth Weight ; Heart Diseases
    Language English
    Publishing date 2023-07-08
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.131171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article: Ablation of Idiopathic Accelerated Idioventricular Rhythm Originating from Right Bundle Branch without Complete Right Bundle Branch Block: A Case Report.

    Liu, Hao-Tien / Chang, Po-Cheng / Wang, Chun-Chieh / Chou, Chung-Chuan

    Acta Cardiologica Sinica

    2023  Volume 39, Issue 1, Page(s) 172–176

    Language English
    Publishing date 2023-01-15
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 1051394-2
    ISSN 1011-6842
    ISSN 1011-6842
    DOI 10.6515/ACS.202301_39(1).20220813B
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Catheter ablation of atrial fibrillation via retrograde aortic approach in a patient with interrupted inferior vena cava: a case report.

    Liu, Hao-Tien / Chang, Po-Cheng / Lee, Hui-Ling / Chou, Chung-Chuan

    Journal of geriatric cardiology : JGC

    2023  Volume 20, Issue 12, Page(s) 877–879

    Language English
    Publishing date 2023-12-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 2421391-3
    ISSN 1671-5411
    ISSN 1671-5411
    DOI 10.26599/1671-5411.2023.12.004
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  5. Article ; Online: Vericiguat suppresses ventricular tachyarrhythmias inducibility in a rabbit myocardial infarction model.

    Chang, Po-Cheng / Lee, Hui-Ling / Wo, Hung-Ta / Liu, Hao-Tien / Wen, Ming-Shien / Chou, Chung-Chuan

    PloS one

    2024  Volume 19, Issue 4, Page(s) e0301970

    Abstract: Background: The VICTORIA trial demonstrated a significant decrease in cardiovascular events through vericiguat therapy. This study aimed to assess the potential mechanisms responsible for the reduction of cardiovascular events with vericiguat therapy in ...

    Abstract Background: The VICTORIA trial demonstrated a significant decrease in cardiovascular events through vericiguat therapy. This study aimed to assess the potential mechanisms responsible for the reduction of cardiovascular events with vericiguat therapy in a rabbit model of myocardial infarction (MI).
    Methods: A chronic MI rabbit model was created through coronary artery ligation. Following 4 weeks, the hearts were harvested and Langendorff perfused. Subsequently, electrophysiological examinations and dual voltage-calcium optical mapping studies were conducted at baseline and after administration of vericiguat at a dose of 5 μmol/L.
    Results: Acute vericiguat therapy demonstrated a significant reduction in premature ventricular beat burden and effectively suppressed ventricular arrhythmic inducibility. The electrophysiological influences of vericiguat therapy included an increased ventricular effective refractory period, prolonged action potential duration, and accelerated intracellular calcium (Cai) homeostasis, leading to the suppression of action potential and Cai alternans. The pacing-induced ventricular arrhythmias exhibited a reentrant pattern, attributed to fixed or functional conduction block in the peri-infarct zone. Vericiguat therapy effectively mitigated the formation of cardiac alternans as well as the development of reentrant impulses, providing additional anti-arrhythmic benefits.
    Conclusions: In the MI rabbit model, vericiguat therapy demonstrates anti-ventricular arrhythmia effects. The vericiguat therapy reduces ventricular ectopic beats, inhibiting the initiation of ventricular arrhythmias. Furthermore, the therapy successfully suppresses cardiac alternans, preventing conduction block and, consequently, the formation of reentry circuits.
    MeSH term(s) Animals ; Rabbits ; Ventricular Fibrillation ; Calcium/therapeutic use ; Myocardial Infarction/complications ; Myocardial Infarction/drug therapy ; Arrhythmias, Cardiac/drug therapy ; Anti-Arrhythmia Agents/therapeutic use ; Heart Block ; Tachycardia, Ventricular/drug therapy ; Heterocyclic Compounds, 2-Ring ; Pyrimidines
    Chemical Substances vericiguat (LV66ADM269) ; Calcium (SY7Q814VUP) ; Anti-Arrhythmia Agents ; Heterocyclic Compounds, 2-Ring ; Pyrimidines
    Language English
    Publishing date 2024-04-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0301970
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  6. Article ; Online: Long-term efficacy of sodium-glucose cotransporter 2 inhibitor therapy in preventing atrial fibrillation recurrence after catheter ablation in type 2 diabetes mellitus patients

    Hao-Tien Liu / Hung-Ta Wo / Po-Cheng Chang / Hui-Ling Lee / Ming-Shien Wen / Chung-Chuan Chou

    Heliyon, Vol 9, Iss 6, Pp e16835- (2023)

    2023  

    Abstract: Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce new-onset atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We aimed to determine the long-term effects of SGLT2i on atrial tachyarrhythmia recurrence after ... ...

    Abstract Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce new-onset atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We aimed to determine the long-term effects of SGLT2i on atrial tachyarrhythmia recurrence after catheter ablation (CA) in T2DM patients. Methods: This retrospective study enrolled consecutive patients with T2DM undergoing CA for AF between January 2016 and December 2021. Patient baseline demographic characteristics and use of anti-diabetic and anti-arrhythmic medications were analyzed. Echocardiographic parameters were obtained one day and 6 months after CA. Results: Our study population comprised 122 patients (70% paroxysmal AF). The baseline patient characteristics were similar between the SGLT2i-treated group (n = 45) and the non-SGLT2i-treated group (n = 77) except for stroke. At 6-month follow-up, body-mass index (BMI) was significantly decreased and left ventricular ejection fraction (LVEF) was significantly increased only in the SGLT2i group. E/e’ was decreased 6 months after CA in both groups. During a mean follow-up of 33.7 ± 21.6 months, 22 of 122 patients had atrial tachyarrhythmia recurrence. The long-term atrial tachyarrhythmia-free survival rate was significantly higher in the SGLT2i-treated patients, and multivariate analysis revealed that AF type and SGLT2i use were independently associated with atrial tachyarrhythmia recurrence after CA. Conclusion: The use of SGLT2i and AF type were independent risk factors associated with atrial tachyarrhythmia recurrence after CA in T2DM patients with AF. This result was at least partly due to the pleiotropic effects of SGLT2i on BMI reduction and left ventricular function improvement.
    Keywords Atrial fibrillation ; Catheter ablation ; Sodium-glucose cotransporter 2 inhibitors ; Type 2 diabetes mellitus ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 616
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Left atrial booster-pump function as a predictive parameter for atrial fibrillation in patients with severely dilated left atrium.

    Yang, Chia-Hung / Liu, Hao-Tien / Lee, Hui-Ling / Lin, Fen-Chiung / Chou, Chung-Chuan

    Quantitative imaging in medicine and surgery

    2022  Volume 12, Issue 4, Page(s) 2523–2534

    Abstract: Background: Left atrial (LA) dimension ≥50 mm had approximately four times the risk of developing atrial fibrillation (AF). The aim of this study was to investigate whether the application of clinical and echocardiographic parameters could differentiate ...

    Abstract Background: Left atrial (LA) dimension ≥50 mm had approximately four times the risk of developing atrial fibrillation (AF). The aim of this study was to investigate whether the application of clinical and echocardiographic parameters could differentiate between the patients having severely dilated left atrium with and without AF.
    Methods: This retrospective cross-sectional study enrolled consecutive patients with LA dimension ≥50 mm and divided them into three groups: no AF (no-AF), paroxysmal AF (PAF) and non-paroxysmal AF (non-PAF) groups. For PAF and non-PAF groups, all patients underwent radiofrequency ablation, and the echocardiographic parameters were obtained on the next day after ablation.
    Results: Our study population comprised 160 patients, including 80, 53, and 27 patients in the non-AF, PAF and non-PAF groups, respectively. The no-AF group had a significantly higher body mass index (kg/m
    Conclusions: LA function plays an important role in the absence of AF in patients with LA dimension ≥50 mm; the late diastolic component of LA strain rate was the only independent variable on multivariate analysis.
    Language English
    Publishing date 2022-03-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-21-954
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  8. Article ; Online: Atrial fibrillation detection using ambulatory smartwatch photoplethysmography and validation with simultaneous holter recording.

    Chang, Po-Cheng / Wen, Ming-Shien / Chou, Chung-Chuan / Wang, Chun-Chieh / Hung, Kuo-Chun

    American heart journal

    2022  Volume 247, Page(s) 55–62

    Abstract: Background: Atrial fibrillation (AF)-associated embolic stroke is preventable, and AF detection may help to prevent stroke in subjects with paroxysmal AF. We aimed to evaluate the AF detection performance of smartwatch photoplethysmography (PPG) and the ...

    Abstract Background: Atrial fibrillation (AF)-associated embolic stroke is preventable, and AF detection may help to prevent stroke in subjects with paroxysmal AF. We aimed to evaluate the AF detection performance of smartwatch photoplethysmography (PPG) and the feasibility of ambulatory monitoring for AF detection in the daily life.
    Design and methods: Consecutive subjects who underwent ambulatory Holter electrocardiogram (ECG) monitoring for AF detection or AF burden evaluation were enrolled. The participants underwent 24 hours of simultaneous Holter ECG monitoring and continuous PPG recording using a Garmin smartwatch. The PPG signals were processed for noise rejection, beat detection, beat labeling, and rhythm labeling for each 5-minute segment. The accuracy of the PPG AF detection was calculated using the corresponding simultaneous Holter ECG as the AF diagnostic standard.
    Results: Among the 200 available participants, 112 participants (56%) developed AF (the AF group). The sensitivity, specificity, and positive predicted value of AF detection in participants were 97.3%, 88.6%, and 91.6%, respectively. The area under the receiver operating characteristic curve was 0.90. When the performance was analyzed in these 5-minute segments, the sensitivity, specificity, and positive predicted values of AF detection were 97.1%, 86.8%, and 89.7%, respectively.
    Conclusions: This study demonstrated the feasibility of ambulatory monitoring for AF detection using a commercial smartwatch in daily life. A smartwatch may be an alternative screening tool to standard ambulatory Holter monitoring.
    MeSH term(s) Atrial Fibrillation/diagnosis ; Electrocardiography ; Electrocardiography, Ambulatory ; Humans ; Monitoring, Ambulatory ; Photoplethysmography
    Language English
    Publishing date 2022-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80026-0
    ISSN 1097-6744 ; 0002-8703
    ISSN (online) 1097-6744
    ISSN 0002-8703
    DOI 10.1016/j.ahj.2022.02.002
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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.15: Show issues Location:
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  9. Article: Long-term efficacy of sodium-glucose cotransporter 2 inhibitor therapy in preventing atrial fibrillation recurrence after catheter ablation in type 2 diabetes mellitus patients.

    Liu, Hao-Tien / Wo, Hung-Ta / Chang, Po-Cheng / Lee, Hui-Ling / Wen, Ming-Shien / Chou, Chung-Chuan

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e16835

    Abstract: Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce new-onset atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We aimed to determine the long-term effects of SGLT2i on atrial tachyarrhythmia recurrence after ... ...

    Abstract Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce new-onset atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We aimed to determine the long-term effects of SGLT2i on atrial tachyarrhythmia recurrence after catheter ablation (CA) in T2DM patients.
    Methods: This retrospective study enrolled consecutive patients with T2DM undergoing CA for AF between January 2016 and December 2021. Patient baseline demographic characteristics and use of anti-diabetic and anti-arrhythmic medications were analyzed. Echocardiographic parameters were obtained one day and 6 months after CA.
    Results: Our study population comprised 122 patients (70% paroxysmal AF). The baseline patient characteristics were similar between the SGLT2i-treated group (n = 45) and the non-SGLT2i-treated group (n = 77) except for stroke. At 6-month follow-up, body-mass index (BMI) was significantly decreased and left ventricular ejection fraction (LVEF) was significantly increased only in the SGLT2i group. E/e' was decreased 6 months after CA in both groups. During a mean follow-up of 33.7 ± 21.6 months, 22 of 122 patients had atrial tachyarrhythmia recurrence. The long-term atrial tachyarrhythmia-free survival rate was significantly higher in the SGLT2i-treated patients, and multivariate analysis revealed that AF type and SGLT2i use were independently associated with atrial tachyarrhythmia recurrence after CA.
    Conclusion: The use of SGLT2i and AF type were independent risk factors associated with atrial tachyarrhythmia recurrence after CA in T2DM patients with AF. This result was at least partly due to the pleiotropic effects of SGLT2i on BMI reduction and left ventricular function improvement.
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e16835
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  10. Article: Retrograde aortic approach for atrial fibrillation ablation with a conventional 3-D mapping catheter: A case report.

    Comandante, Christian / Chang, Po-Cheng / Huang, Yu-Chang / Chou, Chung-Chuan

    Clinical case reports

    2019  Volume 7, Issue 4, Page(s) 719–722

    Abstract: The presence of a Gore-Tex patch can create difficulty in performing transeptal puncture for atrial septal defect patients underwent atrial fibrillation ablation. The maneuverability and stability of using manually operated catheters via retrograde ... ...

    Abstract The presence of a Gore-Tex patch can create difficulty in performing transeptal puncture for atrial septal defect patients underwent atrial fibrillation ablation. The maneuverability and stability of using manually operated catheters via retrograde aortic approach could be overcome by a large-curved catheter to form a loop facilitating approachability to all parts of left atrium.
    Language English
    Publishing date 2019-02-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2075
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