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  1. Book: Elektromagnetische Therapien in der Psychiatrie

    Eschweiler, Gerhard W.

    Elektrokrampftherapie (EKT), transkranielle Magnetstimulation (TMS) und verwandte Verfahren

    2003  

    Author's details G. W. Eschweiler ... (Hrsg.)
    Keywords Elektrokrampftherapie ; Transkranielle magnetische Stimulation
    Subject Transkranielle Magnetstimulation ; Transkranielle magnetoelektrische Stimulation ; Transkranielle kortikale Magnetstimulation ; Kortikale Magnetstimulation ; Transcranielle corticale Magnetstimulation ; TMS ; Elektroschocktherapie ; Elektrokonvulsionstherapie ; Elektrokonvulsive Therapie ; Elektroschockbehandlung ; Schockbehandlung ; Schocktherapie
    Language German
    Size XV, 301 S. : Ill., graph. Darst.
    Publisher Steinkopff
    Publishing place Darmstadt
    Publishing country Germany
    Document type Book
    HBZ-ID HT013693310
    ISBN 3-7985-1351-1 ; 978-3-7985-1351-8
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Diagnostik und multimodale Therapie der Altersdepression : Neue Entwicklungen.

    Eschweiler, Gerhard W

    Zeitschrift fur Gerontologie und Geriatrie

    2017  Volume 50, Issue 2, Page(s) 99–105

    Abstract: Depressive disorders in elderly persons are frequent and can either first be manifested at a younger age and show a recurrent pattern during later life (ICD 10, F33.*) or have an onset beyond 60 years, which is termed late onset depression (LOD). This ... ...

    Title translation Diagnostics and multimodal treatment of depression in old age : New developments.
    Abstract Depressive disorders in elderly persons are frequent and can either first be manifested at a younger age and show a recurrent pattern during later life (ICD 10, F33.*) or have an onset beyond 60 years, which is termed late onset depression (LOD). This LOD has a higher tendency to chronification and implies an increased risk of progression, especially to vascular dementia. The multifactorial genesis of depression in old age includes psychosocial, vascular and metabolic factors and requires multimodal therapy modules at the biological and psychosocial level, which is now increasingly being empirically proven. Depressive disorders with executive and cognitive deficits have to be considered a defined entity with respect to prognosis and treatment. As a first step of treatment watchful waiting is appropriate, especially in depressive adjustment disorders triggered by acute psychosocial stressors (e.g. loss of relatives and conflicts). After 2-4 weeks pharmacological antidepressant therapy should be initiated, at least in a moderate depressive episode. Furthermore, the revised national guidelines for depressive disorders also explicitly recommend psychotherapy as an alternative or supplement to pharmacotherapy in the elderly. Several forms of psychotherapy are emphasized: cognitive behavioral therapy, interpersonal therapy and in particular problem solving, as this is a form of treatment that can also be carried out by other professional groups, thus alleviating the treatment gap caused by the lack of psychotherapists. In summary, a depressive disorder in old age should not induce therapeutic nihilism: after stepped diagnostic assessments, multimodal therapies are individually adapted to the physical, cognitive and social resources of the patients.
    MeSH term(s) Aged ; Aged, 80 and over ; Antidepressive Agents/administration & dosage ; Cognition Disorders/diagnosis ; Cognition Disorders/psychology ; Cognition Disorders/therapy ; Combined Modality Therapy/methods ; Depressive Disorder/diagnosis ; Depressive Disorder/psychology ; Depressive Disorder/therapy ; Evidence-Based Medicine ; Female ; Geriatric Assessment/methods ; Germany ; Humans ; Male ; Psychotherapy/methods ; Treatment Outcome ; Watchful Waiting/methods
    Chemical Substances Antidepressive Agents
    Language German
    Publishing date 2017-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1227032-5
    ISSN 1435-1269 ; 0044-281X ; 0948-6704
    ISSN (online) 1435-1269
    ISSN 0044-281X ; 0948-6704
    DOI 10.1007/s00391-016-1174-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Physical Activity, Sedentary Behavior, and Their Predictors Among Nursing Home Residents-Cross-Sectional Results of the BaSAlt Study.

    Pomiersky, Rebekka / Matting, Leon / Haigis, Daniel / Eschweiler, Gerhard W / Frahsa, Annika / Niess, Andreas / Thiel, Ansgar / Sudeck, Gordon

    Journal of aging and physical activity

    2024  , Page(s) 1–10

    Abstract: Little is known about physical activity (PA) and sedentary behavior (SB) among nursing home residents although PA is known as a health promoter. This study examined PA, SB, and their predictors among nursing home residents (n = 63). Dependent variables ... ...

    Abstract Little is known about physical activity (PA) and sedentary behavior (SB) among nursing home residents although PA is known as a health promoter. This study examined PA, SB, and their predictors among nursing home residents (n = 63). Dependent variables were accelerometry-based PA and SB. Predictor variables included in a path analysis were age, sex, body mass index, Barthel Index, cognitive status (Mini-Mental State Examination), physical performance (hand grip strength and habitual walking speed), and well-being (World Health Organization-5 well-being index). PA was very low (M steps per day = 2,433) and SB was high (M percentage of sedentary time = 89.4%). PA was significantly predicted by age (β = -0.27, p = .008), body mass index (β = -0.29, p = .002), Barthel Index (β = 0.24, p = .040), and hand grip strength (β = 0.30, p = .048). SB was significantly predicted by body mass index (β = 0.27, p = .008) and Barthel Index (β = -0.30, p = .012). Results might be helpful for everyday practice to identify individuals at high risk for low PA and high SB.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ISSN 1543-267X
    ISSN (online) 1543-267X
    DOI 10.1123/japa.2023-0088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The relationship between pre-surgery self-rated health and changes in functional and mental health in older adults: insights from a prospective observational study.

    Mennig, Eva F / Schäfer, Sarah K / Eschweiler, Gerhard W / Rapp, Michael A / Thomas, Christine / Wurm, Susanne

    BMC geriatrics

    2023  Volume 23, Issue 1, Page(s) 203

    Abstract: Background: Elective surgeries are among the most common health stressors in later life and put a significant risk at functional and mental health, making them an important target of research into healthy aging and physical resilience. Large-scale ... ...

    Abstract Background: Elective surgeries are among the most common health stressors in later life and put a significant risk at functional and mental health, making them an important target of research into healthy aging and physical resilience. Large-scale longitudinal research mostly conducted in non-clinical samples provided support of the predictive value of self-rated health (SRH) for both functional and mental health. Thus, SRH may have the potential to predict favorable adaptation processes after significant health stressors, that is, physical resilience. So far, a study examining the interplay between SRH, functional and mental health and their relative importance for health changes in the context of health stressors was missing. The present study aimed at addressing this gap.
    Methods: We used prospective data of 1,580 inpatients (794 complete cases) aged 70 years or older of the PAWEL study, collected between October 2017 and May 2019 in Germany. Our analyses were based on SRH, functional health (Barthel Index) and self-reported mental health problems (PHQ-4) before and 12 months after major elective surgery. To examine changes and interrelationships in these health indicators, bivariate latent change score (BLCS) models were applied.
    Results: Our analyses provided evidence for improvements of SRH, functional and mental health from pre-to-post surgery. BLCS models based on complete cases and the total sample pointed to a complex interplay of SRH, functional health and mental health with bidirectional coupling effects. Better pre-surgery SRH was associated with improvements in functional and mental health, and better pre-surgery functional health and mental health were associated with improvements in SRH from pre-to-post surgery. Effects of pre-surgery SRH on changes in functional health were smaller than those of functional health on changes in SRH.
    Conclusions: Meaningful changes of SRH, functional and mental health and their interplay could be depicted for the first time in a clinical setting. Our findings provide preliminary support for SRH as a physical resilience factor being associated with improvements in other health indicators after health stressors. Longitudinal studies with more timepoints are needed to fully understand the predictive value of SRH for multidimensional health.
    Trial registration: PAWEL study, German Clinical Trials Register, number DRKS00013311. Registered 10 November 2017 - Retrospectively registered, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00013311 .
    MeSH term(s) Humans ; Aged ; Mental Health ; Prospective Studies ; Self Report ; Healthy Aging ; Germany ; Health Status
    Language English
    Publishing date 2023-03-31
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-023-03861-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Diagnostik und multimodale Therapie der Altersdepression : neue Entwicklungen

    Eschweiler, Gerhard W.

    Zeitschrift für Gerontologie und Geriatrie

    2017  Volume 50, Issue 2, Page(s) 99

    Keywords Alter ; Psychotherapie ; Demenz ; Depression
    Language German
    Document type Article
    ZDB-ID 1227032-5
    ISSN 0948-6704
    ISSN 0948-6704
    Database bibnet.org

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  6. Article: Longitudinal cognitive decline characterizes the profile of non-PD-manifest GBA1 mutation carriers.

    Roeben, Benjamin / Liepelt-Scarfone, Inga / Lerche, Stefanie / Zimmermann, Milan / Wurster, Isabel / Sünkel, Ulrike / Schulte, Claudia / Deuschle, Christian / Eschweiler, Gerhard W / Maetzler, Walter / Gasser, Thomas / Berg, Daniela / Brockmann, Kathrin

    NPJ Parkinson's disease

    2024  Volume 10, Issue 1, Page(s) 88

    Abstract: With disease-modifying treatment for Parkinson's disease (PD) associated with variants in the glucocerebrosidase gene (GBA1) under way, the challenge to design clinical trials with non-PD-manifest GBA mutation carriers ( ... ...

    Abstract With disease-modifying treatment for Parkinson's disease (PD) associated with variants in the glucocerebrosidase gene (GBA1) under way, the challenge to design clinical trials with non-PD-manifest GBA mutation carriers (GBA1
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819218-7
    ISSN 2373-8057
    ISSN 2373-8057
    DOI 10.1038/s41531-024-00706-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nichtmedikamentöse Konzepte zu Prävention und Behandlung eines Delirs.

    Thomas, Christine / Spank, Juliane / Weller, Sarah / Eschweiler, Gerhard W

    Zeitschrift fur Gerontologie und Geriatrie

    2021  Volume 54, Issue 8, Page(s) 759–767

    Abstract: Background: Cognitive impairment is common among older patients in German hospitals (40%). Dementia, other brain diseases and frailty significantly increase the risk of delirium and pose great challenges to interdisciplinary and interprofessional teams. ...

    Title translation Nonpharmaceutical concepts for prevention and treatment of delirium.
    Abstract Background: Cognitive impairment is common among older patients in German hospitals (40%). Dementia, other brain diseases and frailty significantly increase the risk of delirium and pose great challenges to interdisciplinary and interprofessional teams. Delirium prevention is achievable but requires complex interdepartmental strategies with specific components for timely recognition of the individual delirium risk, to carry out structured and sustained implementation of appropriate measures for delirium prevention as well as prompt etiological diagnostics and immediate treatment when delirium occurs.
    Objective: The present work aims to shed light on the role of interprofessional and interdisciplinary collaboration in evidence-based, nonpharmacological delirium prevention programs.
    Material and methods: Narrative review of international best practice programs.
    Results: Nonpharmacological prevention of delirium is effective but requires differentiated risk identification, regular delirium screening and daily targeted cognitive activation and sleep promotion. This can only be achieved in close interprofessional collaboration and is mostly carried out interdepartmentally by specialized teams.
    Discussion: Interprofessional multicomponent programs for delirium prevention hold the potential to reduce delirium and complication rates in older high-risk patients in regular care, thereby improving treatment and long-term quality of life. Additional interprofessional delirium prevention teams are deployed in different settings simultaneously and provide regular training on optimal delirium management. Demonstration of the effectiveness of cross-setting programs requires large multicenter studies and is therefore particularly laborious.
    MeSH term(s) Aged ; Cognitive Dysfunction ; Delirium/diagnosis ; Delirium/prevention & control ; Hospitals ; Humans ; Quality of Life
    Language German
    Publishing date 2021-11-24
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1227032-5
    ISSN 1435-1269 ; 0044-281X ; 0948-6704
    ISSN (online) 1435-1269
    ISSN 0044-281X ; 0948-6704
    DOI 10.1007/s00391-021-01988-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Patterns of physical activity among nursing home residents before and during the Covid 19 pandemic-a systematic observation.

    Hahn, Lea-Sofie / Thiel, Ansgar / Trüb, Dorothée / Eschweiler, Gerhard W / Nieß, Andreas M / Sudeck, Gorden / Frahsa, Annika

    European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity

    2023  Volume 20, Issue 1, Page(s) 23

    Abstract: Background: The Covid-19 outbreak in spring of 2020 posed an array of challenges for nursing homes, including promoting resident physical activity (PA). Given the diversity of factors affecting resident PA, we explored how activity patterns outside ... ...

    Abstract Background: The Covid-19 outbreak in spring of 2020 posed an array of challenges for nursing homes, including promoting resident physical activity (PA). Given the diversity of factors affecting resident PA, we explored how activity patterns outside weekly-scheduled structured activities changed during the pandemic and what factors promoted or inhibited PA during the pandemic.
    Methods: We conducted systematic direct observations over 823.5 h in eight nursing homes in Southern Germany in 2020 and 2021.
    Results: In 2020, 84.7% of person observation units were classified as sedentary (average activity level: 1.14 MET). In 2021, the percentage increased to 91.6% of observed person units (average activity level: 1.08 MET) (t = 6.947; p = .000). According to tree classification, influencing factors of PA included mealtime and daytime in 2020 and 2021, as well as presence of men residents only in 2020 and guided low threshold activities in 2021.
    Conclusions: Nursing homes constitute highly sedentary places-an issue exacerbated by access restrictions for external activity experts and significant others as well as behavioural restrictions for residents during the Covid-19 pandemic. Staff could not compensate due to existing time restraints and lack of training in PA promotion. Based on our findings, we recommend future studies to develop feasible and resource-low activities to be integrated into the daily routines of nursing homes.
    Language English
    Publishing date 2023-12-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2236925-9
    ISSN 1861-6909 ; 1813-7253
    ISSN (online) 1861-6909
    ISSN 1813-7253
    DOI 10.1186/s11556-023-00332-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Thesis: Antwortlatenzen im visuellen Kortex bei Katzen mit operativ induziertem Strabismus

    Eschweiler, Gerhard W.

    1987  

    Author's details vorgelegt von Gerhard Wilhelm Eschweiler
    Size 141 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 1987
    HBZ-ID HT003262916
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Sarkopenie, körperliche Aktivität und sedentäres Verhalten von Pflegeheimbewohnenden in Deutschland.

    Haigis, Daniel / Wagner, Silas / Pomiersky, Rebekka / Matting, Leon / Hahn, Lea-Sofie / Eschweiler, Gerhard W / Thiel, Ansgar / Frahsa, Annika / Sudeck, Gorden / Nieß, Andreas M

    Zeitschrift fur Gerontologie und Geriatrie

    2024  

    Abstract: Background: Residents in nursing homes show a high prevalence of the musculoskeletal syndrome sarcopenia and tend not to achieve current physical activity recommendations.: Objective: The aim of this study is to identify differences in physical ... ...

    Title translation Sarcopenia, physical activity and sedentary behavior among nursing home residents in Germany.
    Abstract Background: Residents in nursing homes show a high prevalence of the musculoskeletal syndrome sarcopenia and tend not to achieve current physical activity recommendations.
    Objective: The aim of this study is to identify differences in physical activity and sedentary behavior of sarcopenic residents compared with nonsarcopenic and presarcopenic residents.
    Methods: Sarcopenia assessment was performed among 63 nursing home residents in Baden-Wuerttemberg (D) using the European Working Group on Sarcopenia in Older People 2 specifications. Structured activity sessions (per week), accelerometer-based physical activity (steps/day), and sedentary behavior (percentual/day) were examined. The group comparisons were determined with Kruskal-Wallis tests and Dunn-Bonferroni post hoc tests.
    Results: Significant differences were found for number of steps (p = 0.005) and percentual sedentary behavior (p = 0.019). Moreover, steps per day presented significant results in group comparison for no sarcopenia (2824.4 [423-14275]) with probable sarcopenia (1703.9 [118-5663]) and confirmed/severe sarcopenia (1571.2 [240-2392]) (both p = 0.022; |r| = 0.34). Sedentary behavior demonstrated significant differences in groups with no sarcopenia (87.9% [69.1-94.3]) and with probable sarcopenia (91.7% [80.4-9835]) (p = 0.018; |r| = 0.35).
    Conclusion: Nonsarcopenic residents demonstrated a higher number of steps and lower sedentary behavior compared with presarcopenic and sarcopenic residents. Increasing steps, reducing sedentary behavior and promoting activities of daily living can contribute to the prevention and treatment of sarcopenia in the nursing home setting.
    Language German
    Publishing date 2024-01-26
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 1227032-5
    ISSN 1435-1269 ; 0044-281X ; 0948-6704
    ISSN (online) 1435-1269
    ISSN 0044-281X ; 0948-6704
    DOI 10.1007/s00391-023-02275-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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