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  1. Article: S.P.O.R.R.T.-A Comprehensive Approach to the Assessment and Non-Operative Management of Overuse Knee Conditions in Youth Athletes.

    Davis, Jacob / Doyle, Bridget / Ishii, Haruki / Jayanthi, Neeru

    Current reviews in musculoskeletal medicine

    2023  Volume 16, Issue 12, Page(s) 627–638

    Abstract: ... for these. In this manuscript, we seek to introduce a novel, comprehensive approach: S.P.O.R.R.T. (Skeletal Maturity, Prior ...

    Abstract Purpose of review: The evaluation of a young athlete with an overuse injury to the knee involves a comprehensive approach. There are a number of elements to consider including assessments of skeletal maturity (biologic maturation), workload (training load + competition load), sport specialization status, and biomechanics. The type of injury and treatment, as well as future prognosis, may be influenced by these and other factors.
    Recent findings: Calculating the percentage of predicted adult height (PPAH) is a valuable tool in assessing overuse injury patterns and diagnoses in youth athletes. Modifiable and non-modifiable overuse injury risk factors require monitoring from clinicians as young athletes mature and develop over time. Training and rehabilitation programs should be adapted to account for these. In this manuscript, we seek to introduce a novel, comprehensive approach: S.P.O.R.R.T. (Skeletal Maturity, Prior Injury Risk, One Sport Specialization, Rehabilitation, Return to Play, Training Recommendations) (Fig. 1). Overuse, non-traumatic injuries to the knee in youth athletes will be presented in a case-based and evidence-based model to provide a framework for a comprehensive approach to the assessment and treatment of youth athletes with overuse injuries.
    Language English
    Publishing date 2023-11-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2407827-X
    ISSN 1935-9748 ; 1935-973X
    ISSN (online) 1935-9748
    ISSN 1935-973X
    DOI 10.1007/s12178-023-09874-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Steric and electronic evaluations of P(o-tol)R

    Davis, Wade L / Muller, Alfred

    Acta crystallographica. Section C, Structural chemistry

    2019  Volume 75, Issue Pt 9, Page(s) 1310–1318

    Abstract: The crystal structures of SeP(o-tol)R ...

    Abstract The crystal structures of SeP(o-tol)R
    Language English
    Publishing date 2019-08-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2025703-X
    ISSN 2053-2296 ; 1600-5759 ; 0108-2701
    ISSN (online) 2053-2296 ; 1600-5759
    ISSN 0108-2701
    DOI 10.1107/S2053229619011574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Advanced precautions for today's O.R

    Davis, Mark S

    the operating room professional's handbook for the prevention of sharps injuries and bloodborne exposures

    1999  

    Author's details Mark S. Davis ; [foreword by Julie Gerberding]
    MeSH term(s) General Surgery/standards ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Operating Rooms/standards ; Universal Precautions ; Wounds and Injuries/prevention & control
    Language English
    Size xv, 158 p.
    Publisher Sweinbinder
    Publishing place Atlanta, Ga
    Document type Book
    ISBN 9780966487350 ; 0966487354
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article: Stereospecific microbiological 10-O-demethylation of R-(-)-10,11-dimethoxyaporphines.

    Davis, P J / Abdel-Maksoud, H / Trainor, T M / Vouros, P / Neumeyer, J L

    Biochemical and biophysical research communications

    1985  Volume 127, Issue 2, Page(s) 407–412

    Abstract: The microbiological O-dealkylation of (+) and (-) 10,11-dimethoxyaporphine and the corresponding N ... of substrate stereospecificity for the 6a R(-)enantiomer. Only the (R) 10-demethylated products were isolated ... i.e. (R) iosapocodeine and (R) N-n-propylnor-isoapocodeine. The products were confirmed by comparison ...

    Abstract The microbiological O-dealkylation of (+) and (-) 10,11-dimethoxyaporphine and the corresponding N-n-propyl analog 10,11-dimethoxy-N-n-propylnoraporphine utilizing the fungus Cunninghamella elegans (ATCC 9245) was found to proceed with regioselectivity for the 10-position, and with a high degree of substrate stereospecificity for the 6a R(-)enantiomer. Only the (R) 10-demethylated products were isolated i.e. (R) iosapocodeine and (R) N-n-propylnor-isoapocodeine. The products were confirmed by comparison with their GC/MS spectra.
    MeSH term(s) Apomorphine/analogs & derivatives ; Apomorphine/isolation & purification ; Apomorphine/metabolism ; Biotransformation ; Chemical Phenomena ; Chemistry ; Dealkylation ; Gas Chromatography-Mass Spectrometry ; Mucorales/metabolism ; Stereoisomerism
    Chemical Substances isoapocodeine (36507-69-4) ; 10,11-dimethoxy-N-n-propylnoraporphine (40285-10-7) ; N-n-propylnorisoapocodeine (96158-78-0) ; Apomorphine (N21FAR7B4S)
    Language English
    Publishing date 1985-03-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/s0006-291x(85)80175-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: THIS LOG HELPS HOSPITAL FIGURE O.R. COSTS.

    JACKSON, F C / DAVIS, W C

    Modern hospital

    1964  Volume 103, Page(s) 124–126

    MeSH term(s) Costs and Cost Analysis ; Economics, Hospital ; Hospitals ; Hospitals, Veterans ; Humans ; Medical Records ; Operating Rooms ; Pennsylvania ; Veterans
    Language English
    Publishing date 1964-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391679-0
    ISSN 0026-783X
    ISSN 0026-783X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist.

    Tecle, H / Barrett, S D / Lauffer, D J / Augelli-Szafran, C / Brann, M R / Callahan, M J / Caprathe, B W / Davis, R E / Doyle, P D / Eubanks, D / Lipiniski, W / Mirzadegan, T / Moos, W H / Moreland, D W / Nelson, C B / Pavia, M R / Raby, C / Schwarz, R D / Spencer, C J /
    Thomas, A J / Jaen, J C

    Journal of medicinal chemistry

    1998  Volume 41, Issue 14, Page(s) 2524–2536

    Abstract: The synthesis and SAR of a series of (Z)-(+/-)-1-azabicyclo[2.2. 1]heptan-3-one, O-(3-aryl-2 ... in the R enantiomer, (R)-24Z (CI-1017). ...

    Abstract The synthesis and SAR of a series of (Z)-(+/-)-1-azabicyclo[2.2. 1]heptan-3-one, O-(3-aryl-2-propynyl)oximes are described. The biochemistry and pharmacology of 24Z (PD 142505) and its enantiomers are highlighted. 24Z is functionally an m1-selective muscarinic agonist. Efficacy and m1 selectivity reside in the R enantiomer, (R)-24Z (CI-1017).
    MeSH term(s) 3T3 Cells ; Adenylyl Cyclase Inhibitors ; Animals ; Bridged Bicyclo Compounds, Heterocyclic/chemical synthesis ; Bridged Bicyclo Compounds, Heterocyclic/metabolism ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/toxicity ; CHO Cells ; Cricetinae ; Drug Design ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/toxicity ; Humans ; Inositol Phosphates/biosynthesis ; Male ; Memory/drug effects ; Mice ; Muscarinic Agonists/chemical synthesis ; Muscarinic Agonists/metabolism ; Muscarinic Agonists/pharmacology ; Muscarinic Agonists/toxicity ; Oximes/chemical synthesis ; Oximes/metabolism ; Oximes/pharmacology ; Oximes/toxicity ; Rats ; Receptor, Muscarinic M1 ; Receptors, Muscarinic/drug effects ; Receptors, Muscarinic/metabolism ; Stereoisomerism ; Structure-Activity Relationship ; Transfection
    Chemical Substances Adenylyl Cyclase Inhibitors ; Bridged Bicyclo Compounds, Heterocyclic ; Enzyme Inhibitors ; Inositol Phosphates ; Muscarinic Agonists ; Oximes ; Receptor, Muscarinic M1 ; Receptors, Muscarinic ; PD 142505-0028 (161774-09-0)
    Language English
    Publishing date 1998-07-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/jm960683m
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Comments on the Feature "Potato Early Dying: Management Challenges in a Changing Production Environment".

    Davis, J R / Huisman, O C

    Plant disease

    2019  Volume 88, Issue 11, Page(s) 1168–1171

    Language English
    Publishing date 2019-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS.2004.88.11.1168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ArcTiCA: Arctic tidal constituents atlas.

    Hart-Davis, M G / Howard, S L / Ray, R D / Andersen, O B / Padman, L / Nilsen, F / Dettmering, D

    Scientific data

    2024  Volume 11, Issue 1, Page(s) 167

    Abstract: Tides in the Arctic Ocean affect ocean circulation and mixing, and sea ice dynamics and thermodynamics. However, there is a limited network of available in situ tidal coefficient data for understanding tidal variability in the Arctic Ocean; e.g., the ... ...

    Abstract Tides in the Arctic Ocean affect ocean circulation and mixing, and sea ice dynamics and thermodynamics. However, there is a limited network of available in situ tidal coefficient data for understanding tidal variability in the Arctic Ocean; e.g., the global TICON-3 database contains only 111 sites above 60°N and 21 above 70°N. At the same time, the presence of sea ice and latitude limits of satellite altimetry complicate altimetry-based retrievals of Arctic tidal coefficients. This leads to a reliance on ocean tide models whose accuracy depend on having sufficient in situ data for validation and assimilation. Here, we present a comprehensive new dataset of tidal constituents in the Arctic region, combining analyses of in situ measurements from tide gauges, ocean bottom pressure sensors and GNSS interferometric reflectometry. The new dataset contains 914 measurement sites above 60°N and 399 above 70°N, with each site being quality-assessed and expert guidance provided to help maximise the usage of the dataset. We also compare the dataset to recent tide models.
    Language English
    Publishing date 2024-02-03
    Publishing country England
    Document type Dataset ; Journal Article
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-024-03012-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Hip-spine Assessment of a Novel Surgical Planning Software Provides Acetabular Component Targets That Are Reliable and in Agreement With Current Clinical Recommendations.

    McIntosh, Emily I / Sarpong, Nana O / Steele, John R / Davis, Elizabeth / Muir, Jeffrey M / Canoles, Haley G / Vigdorchik, Jonathan M

    Arthroplasty today

    2024  Volume 25, Page(s) 101288

    Abstract: Background: Spinopelvic immobility has been reported to increase dislocation risk following total hip arthroplasty. Surgically placing acetabular components in a functional orientation has been shown to mitigate risk. The aim of this study was to ... ...

    Abstract Background: Spinopelvic immobility has been reported to increase dislocation risk following total hip arthroplasty. Surgically placing acetabular components in a functional orientation has been shown to mitigate risk. The aim of this study was to evaluate the validity and reliability of novel surgical planning software to generate clinically recommended cup targets.
    Methods: Hip-spine assessments were performed retrospectively on 40 patients. Five reviewers, including 3 arthroplasty-trained surgical fellows and 2 clinical research scientists performed the assessments. Hip-spine assessments consisted of measuring anterior pelvic plane tilt, sacral slope, pelvic incidence, and lumbar lordosis on standing anteroposterior pelvis and lateral standing and seated hip-spine images. Generated cup targets and a control group (40°/20° relative to the anterior pelvic plane) were compared to clinically recommended cup targets. Agreement was defined as a cup position within the recommended range or within 3° of a specific target (eg, 40° inclination) when no range was provided. Intraclass correlation coefficients were used to assess interrater and intrarater reliability, and McNemar's chi-square test was used to measure success relative to the control group.
    Results: The intraclass correlation coefficient was 0.88 for delta sacral slope and 0.92 for pelvic incidence-lumbar lordosis mismatch. For patients with spinopelvic risk factors, the generated targets matched the clinical recommendations in 81% of patients compared to only 16% in the control group.
    Conclusions: Excellent interrater and intrarater reliability was achieved using the novel surgical planning software. The resultant target values agreed with clinical recommendations to a greater extent than the control group.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2023.101288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Volumetric changes in post hemiglossectomy reconstruction with anterolateral thigh free flap versus radial forearm free flap.

    Younis, P A / Davis, S / Sweedan, A O / ElSabbagh, A M / Fernandes, R P

    International journal of oral and maxillofacial surgery

    2023  

    Abstract: The volume of the reconstructed tongue is considered a critical factor for tongue function. Studies investigating the difference in volume loss between the anterolateral thigh free flap (ALTF) and radial forearm free flap (RFFF) used in reconstruction of ...

    Abstract The volume of the reconstructed tongue is considered a critical factor for tongue function. Studies investigating the difference in volume loss between the anterolateral thigh free flap (ALTF) and radial forearm free flap (RFFF) used in reconstruction of the tongue after hemiglossectomy are lacking. The aim of this study was to determine whether there is a significant difference in shrinkage between these two flaps. This was a retrospective study of all patients treated for tongue cancer by hemiglossectomy who underwent either ALTF or RFFF reconstruction at the University of Florida College of Medicine between January 2018 and April 2022. Computed tomography scans were used to measure the volumetric changes in the ALTF and RFFF at two time points over a 6-month period. Of the 85 patients assessed, 10 fulfilled the inclusion criteria: five were reconstructed with an ALTF and five with a RFFF. All underwent adjuvant radiotherapy. The mean ALTF percentage shrinkage was 39.6% ± 3.9%, while for the RFFF it was 51.1% ± 6.2% (P = 0.008). Therefore, it is recommended that the difference in volume loss between the two flaps is taken into consideration. It is suggested that in hemiglossectomy cases, the ALTF is made 1.4 times larger than the defect, while the RFFF is made 1.5 times larger.
    Language English
    Publishing date 2023-12-18
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 353721-3
    ISSN 1399-0020 ; 0901-5027
    ISSN (online) 1399-0020
    ISSN 0901-5027
    DOI 10.1016/j.ijom.2023.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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