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  1. Article ; Online: A

    Basu, Sujay / Barawkar, Dinesh A / Ramdas, Vidya / Waman, Yogesh / Patel, Meena / Panmand, Anil / Kumar, Santosh / Thorat, Sachin / Bonagiri, Rajesh / Jadhav, Dilip / Mukhopadhyay, Partha / Prasad, Vandna / Reddy, B Srinivasa / Goswami, Arnab / Chaturvedi, Sandhya / Menon, Suraj / Quraishi, Azfar / Ghosh, Indraneel / Dusange, Sushant /
    Paliwal, Shalini / Kulkarni, Abhay / Karande, Vikas / Thakre, Rhishikesh / Bedse, Gaurav / Rouduri, Sreekanth / Gundu, Jayasagar / Palle, Venkata P / Chugh, Anita / Mookhtiar, Kasim A

    European journal of medicinal chemistry

    2017  Volume 127, Page(s) 986–996

    Abstract: ... ...

    Abstract A
    MeSH term(s) Adenosine A2 Receptor Antagonists/chemical synthesis ; Adenosine A2 Receptor Antagonists/chemistry ; Adenosine A2 Receptor Antagonists/pharmacology ; Animals ; Brain/drug effects ; Brain/metabolism ; Chemistry Techniques, Synthetic ; Drug Design ; Male ; Mice ; Receptor, Adenosine A2B/metabolism ; Structure-Activity Relationship ; Xanthine/chemical synthesis ; Xanthine/chemistry ; Xanthine/pharmacology
    Chemical Substances Adenosine A2 Receptor Antagonists ; Receptor, Adenosine A2B ; Xanthine (1AVZ07U9S7)
    Language English
    Publishing date 2017-02-15
    Publishing country France
    Document type Journal Article
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2016.11.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 784: Show issues Location:
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  2. Article ; Online: A

    Patel, Khushali J / Kao, Yun-Ting / Llinas, Roxanna J / Bartel, Bonnie

    Plant direct

    2019  Volume 3, Issue 3

    Abstract: The sorting of eukaryotic proteins to various organellar destinations requires receptors that recognize cargo protein targeting signals and facilitate transport into the organelle. One such receptor is the peroxin PEX5, which recruits cytosolic cargo ... ...

    Abstract The sorting of eukaryotic proteins to various organellar destinations requires receptors that recognize cargo protein targeting signals and facilitate transport into the organelle. One such receptor is the peroxin PEX5, which recruits cytosolic cargo carrying a peroxisome-targeting signal (PTS) type 1 (PTS1) for delivery into the peroxisomal lumen (matrix). In plants and mammals, PEX5 is also indirectly required for peroxisomal import of proteins carrying a PTS2 signal because PEX5 binds the PTS2 receptor, bringing the associated PTS2 cargo to the peroxisome along with PTS1 cargo. Despite PEX5 being the PTS1 cargo receptor, previously identified Arabidopsis
    Language English
    Publishing date 2019-03-20
    Publishing country England
    Document type Journal Article
    ISSN 2475-4455
    ISSN (online) 2475-4455
    DOI 10.1002/pld3.128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A

    Liu, Renjie / Patel, Dharmesh / Screen, Hazel R C / Becer, C Remzi

    Bioconjugate chemistry

    2017  Volume 28, Issue 7, Page(s) 1955–1964

    Abstract: Electrospun biodegradable membranes have attracted great attention for a range of tissue engineering applications. Among them, poly(ε-caprolactone) (PCL) is one of the most widely used polymers, owing to its well-controlled biocompatibility and ... ...

    Abstract Electrospun biodegradable membranes have attracted great attention for a range of tissue engineering applications. Among them, poly(ε-caprolactone) (PCL) is one of the most widely used polymers, owing to its well-controlled biocompatibility and biodegradability. However, PCL also has a number of limitations, such as its hydrophobic nature and the lack of functional groups on its side chain, limiting its ability to interact with cells. Herein, we have designed and prepared a series of well-defined A
    MeSH term(s) Animals ; Biocompatible Materials/chemical synthesis ; Cattle ; Cell Adhesion/drug effects ; Cell Death/drug effects ; Glucose/chemistry ; Membranes, Artificial ; Polyesters/chemical synthesis ; Polymers/chemical synthesis ; Polymers/pharmacology ; Tenocytes/metabolism ; Tissue Engineering/methods
    Chemical Substances Biocompatible Materials ; Membranes, Artificial ; Polyesters ; Polymers ; polycaprolactone (24980-41-4) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2017-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1024041-x
    ISSN 1520-4812 ; 1043-1802
    ISSN (online) 1520-4812
    ISSN 1043-1802
    DOI 10.1021/acs.bioconjchem.7b00279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3400: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Book: Body dysmorphic disorder

    Khemlani-Patel, Sony / Neziroglu, Fugen A.

    (Advances in Psychotherapy - Evidence-Based Practice ; Volume 44)

    2022  

    Author's details Sony Khemlani-Patel (Bio Behavioral Institute, Great Neck, NY), Fugen Neziroglu (Bio Behavioral Institute, Great Neck, NY, and Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY)
    Series title Advances in Psychotherapy - Evidence-Based Practice ; Volume 44
    Advances in psychotherapy - evidence based practice
    Collection Advances in psychotherapy - evidence based practice
    Keywords OCD ; abnormal psychology ; body dismorphic disorder ; Dysmorphophobie
    Subject Beachtungswahn ; Schönheitshypochondrie ; Körperdysmorphe Störung ; Körperdysmorphes Syndrom ; Körperdysmorphophobie
    Subject code 150
    Language English
    Size 89, 17 ungezählte Seiten, 25.4 cm x 17.8 cm
    Publisher Hogrefe
    Publishing place Boston, MA ; Göttingen
    Publishing country United States
    Document type Book
    HBZ-ID HT021016104
    ISBN 978-0-88937-500-0 ; 0-88937-500-3 ; 9781616765002 ; 9781616765009 ; 1616765003
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 470 available for loan (reading room) Lesesaal EG

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  5. Article ; Online: The Impact of COVID-19 on Students in the Medical Field.

    Patel, Anjali

    WMJ : official publication of the State Medical Society of Wisconsin

    2024  Volume 122, Issue 5, Page(s) 315–316

    MeSH term(s) Humans ; COVID-19 ; Students
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 441051-8
    ISSN 2379-3961 ; 0043-6542 ; 1098-1861
    ISSN (online) 2379-3961
    ISSN 0043-6542 ; 1098-1861
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 225: Show issues Location:
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  6. Article ; Online: Metal nanoparticles produced by plants with antibacterial properties against Staphylococcus aureus.

    Patel, A

    Brazilian journal of biology = Revista brasleira de biologia

    2023  Volume 82, Page(s) e268052

    Abstract: Staphylococcus aureus (S. aureus) is a pathogenic bacteria that causes a variety of potentially fatal infections. The emergence of antibiotic-resistant strains of S. aureus has made treatment even more difficult. In recent years, nanoparticles have been ... ...

    Abstract Staphylococcus aureus (S. aureus) is a pathogenic bacteria that causes a variety of potentially fatal infections. The emergence of antibiotic-resistant strains of S. aureus has made treatment even more difficult. In recent years, nanoparticles have been used as an alternative therapeutic agent for S. aureus infections. Among various methods for the synthesis of nanoparticles, the method utilizing plant extracts from different parts of a plant, such as root, stem, leaf, flower, seeds, etc. is gaining widespread usage. Phytochemicals present in plant extract are an inexpensive, eco-friendly, natural material that act as reducing and stabilization agent for the nanoparticle synthesis. The utilization of plant-fabricated nanoparticles against S. aureus is currently in trend. The current review discusses recent findings in the therapeutic application of phytofabricated metal-based nanoparticles against Staphylococcus aureus.
    MeSH term(s) Staphylococcus aureus ; Metal Nanoparticles/chemistry ; Staphylococcal Infections/drug therapy ; Plant Leaves/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Plant Extracts/chemistry ; Microbial Sensitivity Tests
    Chemical Substances Anti-Bacterial Agents ; Plant Extracts
    Language English
    Publishing date 2023-03-06
    Publishing country Brazil
    Document type Review ; Journal Article
    ZDB-ID 2036257-2
    ISSN 1678-4375 ; 1519-6984
    ISSN (online) 1678-4375
    ISSN 1519-6984
    DOI 10.1590/1519-6984.268052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 652: Show issues Location:
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  7. Article ; Online: The heart of VIALE-A: Cardiac complications of hypomethylating agents and venetoclax in acute myeloid leukaemia.

    Patel, Shyam A

    British journal of haematology

    2024  Volume 204, Issue 4, Page(s) 1137–1138

    Abstract: As we commemorate 50 years since the introduction of classical 7 + 3 induction chemotherapy for acute myeloid leukaemia (AML), we also embark upon new territory with the advent of novel targeted therapeutics, including BH3 mimetics. To date, we do not ... ...

    Abstract As we commemorate 50 years since the introduction of classical 7 + 3 induction chemotherapy for acute myeloid leukaemia (AML), we also embark upon new territory with the advent of novel targeted therapeutics, including BH3 mimetics. To date, we do not have much large-scale longitudinal data regarding the toxicities of such novel therapies. Johnson et al. perform a comprehensive analysis of cardiac toxicities with hypomethylating agents and venetoclax and offer valuable insight into risk-benefit analysis when considering front-line therapy for AML. Commentary on: Johnson et al. Cardiac events in newly diagnosed acute myeloid leukaemia during treatment with venetoclax + hypomethylating agents. Br J Haematol 2024;204:1232-1237.
    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/diagnosis ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Sulfonamides/therapeutic use ; Heart ; Antineoplastic Combined Chemotherapy Protocols/adverse effects
    Chemical Substances venetoclax (N54AIC43PW) ; Bridged Bicyclo Compounds, Heterocyclic ; Sulfonamides
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.19336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
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  8. Book ; Online ; E-Book: Human sexuality

    Rokach, Ami / Patel, Karishma

    function, dysfunction, paraphilias, and relationships

    2021  

    Author's details Ami Rokach, PhD, Karishma Patel, MSc
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xv, 415 Seiten)
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020875046
    ISBN 978-0-12-819175-0 ; 9780128191743 ; 0-12-819175-9 ; 0128191740
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  9. Book ; Online ; E-Book: Transradial access in interventional radiology

    Fischman, Aaron M. / Patel, Rahul S. / Lookstein, Robert A.

    background, applications and techniques

    2022  

    Author's details Aaron M. Fischman, Rahul S. Patel, Robert A. Lookstein editors
    Keywords Interventional radiology  ; Cardiology ; Oncology
    Subject code 616.0757
    Language English
    Size 1 Online-Ressource (xiii, 248 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021148317
    ISBN 978-3-030-81678-0 ; 9783030816773 ; 3-030-81678-8 ; 303081677X
    DOI 10.1007/978-3-030-81678-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Cutaneous Pharmacokinetics of Topically Applied Novel Dermatological Formulations.

    Patel, Meenakshi / Patel, Ashwini / Desai, Jagruti / Patel, Swayamprakash

    AAPS PharmSciTech

    2024  Volume 25, Issue 3, Page(s) 46

    Abstract: Novel formulations are developed for dermatological applications to address a wide range of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical technology, these formulations strive to provide safer, more effective, and ... ...

    Abstract Novel formulations are developed for dermatological applications to address a wide range of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical technology, these formulations strive to provide safer, more effective, and patient-friendly solutions for dermatological concerns, ultimately improving the overall quality of dermatological care. The article explores the different types of novel dermatological formulations, including nanocarriers, transdermal patches, microsponges, and microneedles, and the techniques involved in the cutaneous pharmacokinetics of these innovative formulations. Furthermore, the significance of knowing cutaneous pharmacokinetics and the difficulties faced during pharmacokinetic assessment have been emphasized. The article examines all the methods employed for the pharmacokinetic evaluation of novel dermatological formulations. In addition to a concise overview of earlier techniques, discussions on novel methodologies, including tape stripping, in vitro permeation testing, cutaneous microdialysis, confocal Raman microscopy, and matrix-assisted laser desorption/ionization mass spectrometry have been conducted. Emerging technologies like the use of microfluidic devices for skin absorption studies and computational models for predicting drug pharmacokinetics have also been discussed. This article serves as a valuable resource for researchers, scientists, and pharmaceutical professionals determined to enhance the development and understanding of novel dermatological drug products and the complex dynamics of cutaneous pharmacokinetics.
    MeSH term(s) Humans ; Skin/metabolism ; Administration, Cutaneous ; Skin Absorption ; Technology, Pharmaceutical ; Microdialysis/methods
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2052070-0
    ISSN 1530-9932 ; 1530-9932
    ISSN (online) 1530-9932
    ISSN 1530-9932
    DOI 10.1208/s12249-024-02763-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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