Article: Cannabis-induced psychosis: clinical characteristics and its differentiation from schizophrenia with and without cannabis use.
2021 Volume 33, Issue 2, Page(s) 95–108
Abstract: Cannabis use is considered an established risk factor for psychosis development. Differentiating between cannabis-induced disorders and schizophrenia is useful for prognostic and therapeutic purposes. Three inpatients groups were differentiated: cannabis- ...
| Title translation | Psicosis inducida por cannabis: características clínicas y su diferenciación con la esquizofrenia con y sin consumo de cannabis asociado. |
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| Abstract | Cannabis use is considered an established risk factor for psychosis development. Differentiating between cannabis-induced disorders and schizophrenia is useful for prognostic and therapeutic purposes. Three inpatients groups were differentiated: cannabis-induced psychosis (CIP) (n = 69; mean age = 27.4, SD = 6.5; 82.6% males), schizophrenia with cannabis abuse or dependence (SZ + CB) (n = 57; mean age = 31.9, SD = 10.1; 94.7% males) and schizophrenia without cannabis abuse or dependence (SZ) (n = 181; mean age = 41.8, SD = 13.3; 54.1% males). The Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV) scale was used to differentiate induced psychosis. The CIP group presented lower mean scores on the negative PANSS subscale (M = 12.9, SD = 5.9; F = 32.24, p < 0.001), fewer auditory hallucinations (60.3%; X² = 6.60, p = 0.037) and greater presence of mania (26.1% vs. 12.3%; X² = 32.58, p < 0.001) than the SZ + CB group. There were few clinical differences between patients with schizophrenia, regardless of previous cannabis use. The age of first admission due to psychosis was lower in both psychotic inpatients groups with cannabis use (M = 26.1, SD = 6.4 in CIP and M = 25.3, SD = 6.2 in SZ + CB; X² = 20.02, p < 0,001). A clinical pattern characteristic of cannabis-induced psychosis was not observed, but the precipitating role of cannabis in the appearance of psychotic symptoms was demonstrated, given the lower age of first admission due to psychosis in cannabis user groups. |
| MeSH term(s) | Adult ; Cannabis ; Humans ; Marijuana Abuse/complications ; Psychotic Disorders/etiology ; Risk Factors ; Schizophrenia/chemically induced |
| Language | Spanish |
| Publishing date | 2021-03-31 |
| Publishing country | Spain |
| Document type | Journal Article |
| ZDB-ID | 2018873-0 |
| ISSN | 0214-4840 |
| ISSN | 0214-4840 |
| DOI | 10.20882/adicciones.1251 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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