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  1. Article: Progress of Molecular Display Technology Using

    Shibasaki, Seiji / Ueda, Mitsuyoshi

    Microorganisms

    2023  Volume 11, Issue 1

    Abstract: In the long history of microorganism use, yeasts have been developed as hosts for producing biologically active compounds or for conventional fermentation. Since the introduction of genetic engineering, recombinant proteins have been designed and ... ...

    Abstract In the long history of microorganism use, yeasts have been developed as hosts for producing biologically active compounds or for conventional fermentation. Since the introduction of genetic engineering, recombinant proteins have been designed and produced using yeast or bacterial cells. Yeasts have the unique property of expressing genes derived from both prokaryotes and eukaryotes.
    Language English
    Publishing date 2023-01-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11010125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Utilization of Macroalgae for the Production of Bioactive Compounds and Bioprocesses Using Microbial Biotechnology.

    Shibasaki, Seiji / Ueda, Mitsuyoshi

    Microorganisms

    2023  Volume 11, Issue 6

    Abstract: To achieve sustainable development, alternative resources should replace conventional resources such as fossil fuels. In marine ecosystems, many macroalgae grow faster than terrestrial plants. Macroalgae are roughly classified as green, red, or brown ... ...

    Abstract To achieve sustainable development, alternative resources should replace conventional resources such as fossil fuels. In marine ecosystems, many macroalgae grow faster than terrestrial plants. Macroalgae are roughly classified as green, red, or brown algae based on their photosynthetic pigments. Brown algae are considered to be a source of physiologically active substances such as polyphenols. Furthermore, some macroalgae can capture approximately 10 times more carbon dioxide from the atmosphere than terrestrial plants. Therefore, they have immense potential for use in the environment. Recently, macroalgae have emerged as a biomass feedstock for bioethanol production owing to their low lignin content and applicability to biorefinery processes. Herein, we provided an overview of the bioconversion of macroalgae into bioactive substances and biofuels using microbial biotechnology, including engineered yeast designed using molecular display technology.
    Language English
    Publishing date 2023-06-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11061499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Progress of Molecular Display Technology Using Saccharomyces cerevisiae to Achieve Sustainable Development Goals

    Seiji Shibasaki / Mitsuyoshi Ueda

    Microorganisms, Vol 11, Iss 125, p

    2023  Volume 125

    Abstract: In the long history of microorganism use, yeasts have been developed as hosts for producing biologically active compounds or for conventional fermentation. Since the introduction of genetic engineering, recombinant proteins have been designed and ... ...

    Abstract In the long history of microorganism use, yeasts have been developed as hosts for producing biologically active compounds or for conventional fermentation. Since the introduction of genetic engineering, recombinant proteins have been designed and produced using yeast or bacterial cells. Yeasts have the unique property of expressing genes derived from both prokaryotes and eukaryotes. Saccharomyces cerevisiae is one of the well-studied yeasts in genetic engineering. Recently, molecular display technology, which involves a protein-producing system on the yeast cell surface, has been established. Using this technology, designed proteins can be displayed on the cell surface, and novel abilities are endowed to the host yeast strain. This review summarizes various molecular yeast display technologies and their principles and applications. Moreover, S. cerevisiae laboratory strains generated using molecular display technology for sustainable development are described. Each application of a molecular displayed yeast cell is also associated with the corresponding Sustainable Development Goals of the United Nations.
    Keywords yeast ; genetic engineering ; molecular display technology ; sustainable development ; sustainable development goals (SDGs) ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Utilization of Macroalgae for the Production of Bioactive Compounds and Bioprocesses Using Microbial Biotechnology

    Seiji Shibasaki / Mitsuyoshi Ueda

    Microorganisms, Vol 11, Iss 1499, p

    2023  Volume 1499

    Abstract: To achieve sustainable development, alternative resources should replace conventional resources such as fossil fuels. In marine ecosystems, many macroalgae grow faster than terrestrial plants. Macroalgae are roughly classified as green, red, or brown ... ...

    Abstract To achieve sustainable development, alternative resources should replace conventional resources such as fossil fuels. In marine ecosystems, many macroalgae grow faster than terrestrial plants. Macroalgae are roughly classified as green, red, or brown algae based on their photosynthetic pigments. Brown algae are considered to be a source of physiologically active substances such as polyphenols. Furthermore, some macroalgae can capture approximately 10 times more carbon dioxide from the atmosphere than terrestrial plants. Therefore, they have immense potential for use in the environment. Recently, macroalgae have emerged as a biomass feedstock for bioethanol production owing to their low lignin content and applicability to biorefinery processes. Herein, we provided an overview of the bioconversion of macroalgae into bioactive substances and biofuels using microbial biotechnology, including engineered yeast designed using molecular display technology.
    Keywords macroalgae ; phlorotannin ; molecular display ; bioethanol ; xylan ; mannitol ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Successful management of biliary atresia in an 834 g preterm infant.

    Goto, Hiroki / Iwatani, Sota / Ikuta, Toshihiko / Nakayama, Kurita / Ueda, Masaaki / Hatakeyama, Tadashi / Yoshimoto, Seiji

    Pediatrics international : official journal of the Japan Pediatric Society

    2024  Volume 65, Issue 1, Page(s) e15665

    MeSH term(s) Infant ; Humans ; Infant, Newborn ; Biliary Atresia/diagnosis ; Biliary Atresia/surgery ; Infant, Premature ; Portoenterostomy, Hepatic ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2024-02-21
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.15665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 848: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: TAV-in-TAV for paravalvular aortic regurgitation due to a deeply implanted Navitor transcatheter aortic valve.

    Katagiri, Yuki / Yamasaki, Kazumasa / Ueda, Takashi / Misawa, Manabu / Yamazaki, Seiji / Saito, Shigeru

    Cardiovascular intervention and therapeutics

    2023  Volume 39, Issue 1, Page(s) 101–102

    MeSH term(s) Humans ; Aortic Valve/surgery ; Aortic Valve Insufficiency/diagnosis ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Aortic Valve Stenosis/surgery ; Transcatheter Aortic Valve Replacement/adverse effects ; Heart Valve Prosthesis/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-08-16
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2581654-8
    ISSN 1868-4297 ; 1868-4300
    ISSN (online) 1868-4297
    ISSN 1868-4300
    DOI 10.1007/s12928-023-00951-w
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4771: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Clinical Utility of the H

    Hirano, Reina / Ikemura, Nobuhiro / Nguyen, Dan D / Jones, Philip G / Kimura, Takehiro / Katsumata, Yoshinori / Ueda, Ikuko / Takatsuki, Seiji / Spertus, John A / Kohsaka, Shun

    JACC. Heart failure

    2024  

    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Letter
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.12.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Reducing the Time Before the Console in Robotic-Assisted Laparoscopic Hysterectomy].

    Hoshino, Kaori / Kurita, Tomoko / Tohyama, Atsushi / Kinjo, Yasuyuki / Nishimura, Kazuaki / Harada, Hiroshi / Ueda, Taeko / Kagami, Seiji / Yoshino, Kiyoshi / Matsuura, Yusuke

    Journal of UOEH

    2024  Volume 46, Issue 1, Page(s) 37–43

    Abstract: Robotic-assisted surgery enables precise manipulations with magnified vision, stereoscopic vision, and forceps with multi-joint functions. It requires unique procedures such as position setting, port placement, roll-in, and docking, which lead to ... ...

    Abstract Robotic-assisted surgery enables precise manipulations with magnified vision, stereoscopic vision, and forceps with multi-joint functions. It requires unique procedures such as position setting, port placement, roll-in, and docking, which lead to prolonged operation and anesthesia time. Five conditions described below were established at our institution to reduce the time to the initiation of console: (1) changing the patients' position from the flat lithotomy position to the spread legs position; (2) attaching a Hasson cone to hold the umbilical cannula stable; (3) changing the cannula's obturator (inner tube) from blunt to bladeless; (4) fixing the team, and (5) conducting regular docking training. These outcomes were examined in this study. The study included 77 patients who underwent robotic-assisted total hysterectomy for benign uterine disease and stage IA uterine cancer at our individual institution between April 2019 and July 2022. We compared the median time from anesthesia to console initiation between the first half group (cases 1-40) and the second half group (cases 41-77). The former required 91.5 (53-131) minutes, whereas the latter required 59 (37-126) minutes. Appropriate equipment selection and team education can reduce the time to console initiation.
    MeSH term(s) Female ; Humans ; Robotic Surgical Procedures/methods ; Laparoscopy/methods ; Hysterectomy/education ; Hysterectomy/methods ; Uterine Neoplasms
    Language Japanese
    Publishing date 2024-03-13
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 632724-2
    ISSN 2187-2864 ; 0387-821X
    ISSN (online) 2187-2864
    ISSN 0387-821X
    DOI 10.7888/juoeh.46.37
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2868: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: The proteinuria-lowering effects of dapagliflozin are associated with an initial decline in estimated glomerular filtration rate in patients with chronic kidney disease.

    Murakoshi, Maki / Kobayashi, Takashi / Kihara, Masao / Ueda, Seiji / Suzuki, Yusuke / Gohda, Tomohito

    Nephrology (Carlton, Vic.)

    2023  Volume 28, Issue 10, Page(s) 540–547

    Abstract: Aim: Sodium-glucose co-transporter-2 inhibitor, dapagliflozin (DAPA) reduced albuminuria and slowed down the decline in estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (CKD) in the DAPA-CKD trial. However, proteinuria ...

    Abstract Aim: Sodium-glucose co-transporter-2 inhibitor, dapagliflozin (DAPA) reduced albuminuria and slowed down the decline in estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (CKD) in the DAPA-CKD trial. However, proteinuria (albuminuria) does not necessarily decrease in all patients in real-world clinical settings. Therefore, we aimed to identify the clinical characteristics of patients with CKD and decreased proteinuria in response to DAPA treatment.
    Methods: Of 106 patients with CKD, 54 patients were finally included who received 10 mg of DAPA once daily. Patients whose urinary protein-to-creatinine ratio (UPCR) decreased by >30% or ≤30% from baseline after 1 month of treatment were defined as responders and non-responders, respectively.
    Results: At baseline, median eGFR and UPCR were 45.3 mL/min/1.73 m
    Conclusion: The percent changes in UPCR were positively associated with the initial decline rate in eGFR in patients with CKD with a UPCR ≥0.5 g/gCr at baseline after 1 month of DAPA treatment.
    MeSH term(s) Humans ; Glomerular Filtration Rate ; Albuminuria/complications ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/drug therapy ; Proteinuria/diagnosis ; Proteinuria/drug therapy ; Proteinuria/etiology ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Diabetes Mellitus, Type 2/complications
    Chemical Substances dapagliflozin (1ULL0QJ8UC) ; Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2023-06-25
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1303661-0
    ISSN 1440-1797 ; 1320-5358
    ISSN (online) 1440-1797
    ISSN 1320-5358
    DOI 10.1111/nep.14207
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    Zs.A 4822: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article: A case of subarachnoid hemorrhage caused by multiple cerebral aneurysms due to segmental arterial mediolysis.

    Tokuda, Takaho / Tajiri, Seiji / Ueda, Yutaka / Ohmori, Yuki / Mukasa, Akitake

    Surgical neurology international

    2022  Volume 13, Page(s) 175

    Abstract: Background: Segmental arterial mediolysis (SAM) is a condition in which an aneurysm is formed by causing lysis of the media and remodeling of blood vessels. Short-term recurrence has been reported in abdominal aortic aneurysms. Cerebral aneurysms have ... ...

    Abstract Background: Segmental arterial mediolysis (SAM) is a condition in which an aneurysm is formed by causing lysis of the media and remodeling of blood vessels. Short-term recurrence has been reported in abdominal aortic aneurysms. Cerebral aneurysms have been suggested to form in a short period not only in the abdominal cavity but also in the intracranial arteries in SAM.
    Case description: A 36-year-old pregnant woman at 35 weeks' gestation developed sudden headache and disorientation. Head magnetic resonance imaging showed a small amount of subarachnoid hemorrhage in the right ambient cistern. A fusiform cerebral aneurysm was found in the periphery of the right superior cerebellar artery, and small saccular aneurysms were found in the periphery of the right posterior cerebral artery and left posterior inferior cerebral artery. After delivery of the fetus, endovascular embolization of the ruptured aneurysm was performed. However, 10-week postoperatively, she developed sudden headache. Hemorrhage was found in the fourth ventricle, and enlargement of the left posterior inferior cerebellar artery (PICA) peripheral aneurysm and disappearance of the right posterior cerebral artery peripheral aneurysm were confirmed. A ruptured aneurysm in the peripheral left PICA was removed after trapping. Intraoperatively, an unruptured thrombosed aneurysm that was not visualized by imaging was also removed. Histopathological examination showed no calcification or inflammation, rupture of the internal elastic lamina, and lack of segmentation, and SAM was diagnosed.
    Conclusion: In atypical dissecting aneurysms, SAM should be considered as a differential diagnosis. Systemic examination and short-term follow-up are also necessary.
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_282_2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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