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  1. Article ; Online: A Ping Pong Ball in the Left Ventricle.

    Galzerano, Domenico / Eltayeb, Abdalla / Alamri, Soaad / Alamri, Sultan / Arbili, Lana / Mohammed, Shamayel

    Journal of cardiothoracic and vascular anesthesia

    2023  Volume 37, Issue 10, Page(s) 2153–2156

    Abstract: Diagnosing cardiac masses, especially those related to cardiac tumors, is often challenging in clinical practice. Though myxomas are the most common and well-known benign cardiac tumors, other rare and often-neglected tumors can be difficult to diagnose. ...

    Abstract Diagnosing cardiac masses, especially those related to cardiac tumors, is often challenging in clinical practice. Though myxomas are the most common and well-known benign cardiac tumors, other rare and often-neglected tumors can be difficult to diagnose. In this case report, the authors describe a left ventricular cardiac mass with unique and striking imaging features.
    MeSH term(s) Humans ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/surgery ; Heart Neoplasms/diagnostic imaging ; Heart Neoplasms/surgery ; Myxoma/diagnostic imaging ; Myxoma/surgery ; Diagnosis, Differential
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2023.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Original Article--Mid-term Clinical and Hemodynamic Outcomes in Middle Age Patients Post Trifecta™ (Abbott) Aortic Valve Replacement: A Single-center Study.

    Khaliel, Feras H / Al Aboud, Mohammed S / Althibait, Suha A / Yezli, Saber / Al Muaythir, Elaf A / Alamro, Bandar / Galzerano, Domenico

    Journal of the Saudi Heart Association

    2024  Volume 36, Issue 1, Page(s) 1–7

    Abstract: Background: Trifecta™ is an externally wrapped bovine pericardial aortic valve with a favorable hemodynamic performance and acceptable rate of freedom from structural valve degeneration. However, recent reports of early Trifecta valve failure question ... ...

    Abstract Background: Trifecta™ is an externally wrapped bovine pericardial aortic valve with a favorable hemodynamic performance and acceptable rate of freedom from structural valve degeneration. However, recent reports of early Trifecta valve failure question its durability. Rheumatic valve disease in young population is predominant, there is no data on the Trifecta performance, durability or safety available worldwide over the middle age population, as well as there are no previous similar reports from Middle East region. We report on mid-term clinical and hemodynamic performance of Trifecta valve in middle age population with small aortic annuls, a single center report.
    Methods: A retrospective study of all patients who underwent Trifecta™ SAVR between June 2014 and December 2019 at a cardiac center in Riyadh, Saudi Arabia. Hemodynamic performance was analyzed by longitudinal Doppler echocardiography.
    Results: During a 5.5-year period, a total of 24 patients underwent SAVR with Trifecta™ valves at our heart center. Patients had a median age of 47.1 years (IQR = 37) and male:female ratio of 1:1. Patients had a median EuroScoreII of 2 (IQR = 1). The 19 mm valve was the most frequently used (29.2%) followed by the 21 mm and 23 mm (both 25.0%). Concomitant procedure was (54.2%). All patients survived their operations and most (87.0%) had their symptoms relieved. A 30-day mortality rate of 4.2%. Patients were followed up for a median of 58.5 months (IQR = 38), during which 8.3% required re interventions, giving an overall freedom from re-intervention of 91.7%. The re-intervention after valve implantation was recorded in two (8.3%). These re-interventions were performed 3 years post initial surgery and were due to structural valve deterioration (SVD). The mean gradient reduced significantly from 43.6 ± 23.9 mmHg (median = 41, IQR = 21) at baseline to 13.0 ± 7.4 mmHg (median = 11, IQR = 5) one-week post intervention (p < 0.001). The average mean gradients were stable from post-operation to follow-up (13.0 ± 7.4 vs 14.1 ± 6.4 mmHg).
    Conclusion: Our study confirms excellent mid-term durability, clinical and hemodynamic performance of the Trifecta™ valve in middle age population, despite the fact of non-statically significant trend-up of transvalvular gradient over the follow up period. Further long-term studies with larger sample-size are warranted to confirm these results.
    Language English
    Publishing date 2024-03-03
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515647-0
    ISSN 1016-7315
    ISSN 1016-7315
    DOI 10.37616/2212-5043.1366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Non-atherosclerotic coronary artery disease: an overview of a heterogeneous disease.

    Landi, Irene / Alkhabaz, Anas / Abou Shaar, Bader / Galzerano, Domenico / Albert-Brotons, Dimpna / Tahir, Mohammed / Eltayeb, Abdulla / Alenazy, Ali / Arshi, Fatima / Limongelli, Giuseppe / Bossone, Eduardo / Vriz, Olga

    Coronary artery disease

    2024  Volume 35, Issue 4, Page(s) 333–347

    MeSH term(s) Humans ; Coronary Artery Disease/diagnosis
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Editorial ; Introductory Journal Article ; Journal Article
    ZDB-ID 1047268-x
    ISSN 1473-5830 ; 0954-6928
    ISSN (online) 1473-5830
    ISSN 0954-6928
    DOI 10.1097/MCA.0000000000001317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Ross Procedure: Imaging, Outcomes and Future Directions in Aortic Valve Replacement.

    Galzerano, Domenico / Kholaif, Naji / Al Amro, Bandar / Al Admawi, Mohammed / Eltayeb, Abdalla / Alshammari, Amal / Di Salvo, Giovanni / Al-Halees, Zohair Y

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: The Ross procedure is gaining recognition as a significant option for aortic valve replacement (AVR), and is particularly beneficial in specific patient groups. Although categorized as a class IIb recommendation in the 2020 American College of Cardiology ...

    Abstract The Ross procedure is gaining recognition as a significant option for aortic valve replacement (AVR), and is particularly beneficial in specific patient groups. Although categorized as a class IIb recommendation in the 2020 American College of Cardiology (ACC)/American Heart Association (AHA), and the European Society of Cardiology (ESC) management guidelines on valvular heart disease, recent studies bolster its credibility. Research, including a propensity-matched study, underlines the Ross procedure's association with enhanced long-term survival and reduced adverse valve-related events compared to other AVR types. This positions the Ross procedure as a primary option for AVR in young and middle-aged adults within specialized centers, and potentially the only choice for children and infants requiring AVR. This review meticulously examines the Ross procedure, covering historical perspectives, surgical techniques, imaging, and outcomes, including hemodynamic performance and quality of life, especially focusing on pediatric and young adult patients. It explores contemporary techniques and innovations like minimally invasive approaches and tissue engineering, underscoring ongoing research and future directions. A summarization of comparative studies and meta-analyses reiterates the Ross procedure's superior long-term outcomes, valve durability, and preservation of the left ventricular function, accentuating the crucial role of patient selection and risk stratification, and pinpointing areas for future research.
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Echocardiography in Simple Congenital Heart Diseases: Guiding Adult Patient Management.

    Galzerano, Domenico / Pergola, Valeria / Eltayeb, Abdalla / Ludovica, Fulgione / Arbili, Lana / Tashkandi, Loay / Michele, Sara Di / Barchitta, Agatella / Parato, Maurizio Vito / Salvo, Giovanni Di

    Journal of cardiovascular echography

    2024  Volume 33, Issue 4, Page(s) 171–182

    Abstract: This article provides comprehensive insights into the evaluation of simple congenital heart diseases (CHDs) in adults, emphasizing the pivotal role of echocardiography. By focusing on conditions such as congenital aortic stenosis, aortic coarctation, ... ...

    Abstract This article provides comprehensive insights into the evaluation of simple congenital heart diseases (CHDs) in adults, emphasizing the pivotal role of echocardiography. By focusing on conditions such as congenital aortic stenosis, aortic coarctation, patent ductus arteriosus, atrial septal defects (ASDs), and ventricular septal defects (VSDs), the review underscores echocardiography's intricate contributions to precise clinical decision-making. Echocardiography serves as the primary imaging modality, offering high-resolution visualization of anatomical anomalies and quantification of hemodynamic parameters. It enables tailored therapeutic strategies through its capacity to discern the dimensions, spatial orientation, and dynamic shunt dynamics of defects such as ASDs and VSDs. Moreover, echocardiography's advanced techniques, such as tissue Doppler imaging and speckle tracking, provide detailed insights into atrial mechanics, diastolic function, and ventricular filling kinetics. Integration of echocardiographic findings into clinical practice empowers clinicians to create personalized interventions based on quantified ventricular function, which spans systolic and diastolic aspects. This approach facilitates risk stratification and therapeutic planning, particularly pertinent in heart failure management within the CHD patient population. In summary, echocardiography transcends its role as an imaging tool, emerging as a precision-guided instrument adept at navigating the complexities of simple CHD in adults. Its ability to expedite diagnosis, quantify hemodynamic impacts, and unravel multifaceted functional dynamics culminates in a comprehensive depiction of these conditions. The fusion of these insights with clinical expertise empowers clinicians to navigate the intricate pathways of CHD, crafting tailored therapeutic strategies characterized by precision and efficacy.
    Language English
    Publishing date 2024-02-26
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/jcecho.jcecho_52_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Three-dimensional printing in integrated multi-modality imaging approach for management of prosthetic valves infective endocarditis.

    Eltayeb, Abdalla / Khan, Shahid / Dib, Salam / Musthaq, Ali / Elshaer, Ahmed / Shaik, Abdullah / Galzerano, Domenico / Fadel, Bahaa / Aladmawi, Mohamed / Vriz, Olga

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2022  Volume 93, Issue 4

    Abstract: After heart failure, infectious endocarditis is the second leading cause of death in patients with prosthetic valves. Aortic pseudoaneurysms are a serious complication of infective endocarditis in mechanical or bioprosthetic aortic prostheses. Diagnostic ...

    Abstract After heart failure, infectious endocarditis is the second leading cause of death in patients with prosthetic valves. Aortic pseudoaneurysms are a serious complication of infective endocarditis in mechanical or bioprosthetic aortic prostheses. Diagnostic and management challenges are posed by aortic pseudoaneurysms. In these cases, a multi-modality imaging approach with a heart team is recommended. We described two cases of aortic pseudoaneurysms that developed as a result of infective endocarditis. The first case involved a TAVI patient who developed infective endocarditis as a result of diabetic foot complications. Because traditional echocardiography and computed tomography failed to show the anatomy of the lesion, we used 3D printing to show the anatomy, extension of the pseudoaneurysm, and proximity to the right coronary artery. The second case involved a patient who underwent Bentall's surgery with an aortic root and mechanical aortic valve and later developed infective endocarditis complicated by pseudoaneurysms. In this case, 3D printing was used for preoperative surgical planning.
    MeSH term(s) Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aneurysm, False/diagnostic imaging ; Aneurysm, False/etiology ; Aneurysm, False/surgery ; Endocarditis/diagnosis ; Endocarditis/diagnostic imaging ; Endocarditis, Bacterial/complications ; Endocarditis, Bacterial/diagnostic imaging ; Endocarditis, Bacterial/surgery ; Printing, Three-Dimensional ; Multimodal Imaging/adverse effects ; Heart Valve Prosthesis/adverse effects
    Language English
    Publishing date 2022-11-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2022.2479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Giant Iatrogenic Pseudoaneurysm of Right Pulmonary Artery Compressing the Left Atrium.

    Al Sergani, Reem / Galzerano, Domenico / Parato, Vito Maurizio / Al Admawi, Mohammed / AlJufan, Mansour

    JACC. Case reports

    2020  Volume 2, Issue 6, Page(s) 870–872

    Abstract: We describe a case of giant pseudoaneurysm of the right pulmonary artery compressing the left atrium after percutaneous pulmonary valve implantation and right pulmonary artery dilatation. Such a complication mimicking an intracavity left atrial mass and ... ...

    Abstract We describe a case of giant pseudoaneurysm of the right pulmonary artery compressing the left atrium after percutaneous pulmonary valve implantation and right pulmonary artery dilatation. Such a complication mimicking an intracavity left atrial mass and treated successfully by stent placement has never, to the best of our knowledge, been reported. (
    Language English
    Publishing date 2020-06-17
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.03.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Three-Dimensional Echocardiographic Imaging of a Gerbode Defect Complicating Transcatheter Aortic Valve Replacement.

    Al Sergani, Hani / Galzerano, Domenico / Vriz, Olga / Al Buraiki, Jehad

    Journal of cardiovascular echography

    2019  Volume 29, Issue 1, Page(s) 14–16

    Abstract: We describe a case of a 77-year-old male who underwent transcatheter aortic valve implantation (TAVR) with Edwards SAPIEN XT size 26 mm for severe aortic stenosis. Postprocedural transesophageal echocardiography (TEE) showed left-to-right shunt between ... ...

    Abstract We describe a case of a 77-year-old male who underwent transcatheter aortic valve implantation (TAVR) with Edwards SAPIEN XT size 26 mm for severe aortic stenosis. Postprocedural transesophageal echocardiography (TEE) showed left-to-right shunt between the left ventricular outflow tract just below the bioprosthesis and the right atrium across the atrioventricular septum (Gerbode defect). Three-dimensional echocardiography (3DE) allowed a detailed anatomical imaging of the shape and the location of a small, circular, atrioventricular defect that was a type II, direct, supravalvular, Gerbode-type defect. This is the third report of a Gerbode defect after TAVR whose diagnosis has important implications on clinical decision-making. TEE plays a key role; its diagnostic ability is enriched by the additional value of 3DE.
    Language English
    Publishing date 2019-04-05
    Publishing country India
    Document type Case Reports
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/jcecho.jcecho_56_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: A Case of Shunting Postoperative Patent Foramen Ovale Under Mechanical Ventilation Controlled by Different Ventilator Settings.

    Pragliola, Claudio / Di Michele, Sara / Galzerano, Domenico

    Clinics and practice

    2017  Volume 7, Issue 3, Page(s) 969

    Abstract: A 56-year old male with ischemic heart disease and an unremarkable preoperative echocardiogram underwent surgical coronary revascularization. An intraoperative post pump trans-esophageal echocardiogram (TOE) performed while the patient was being ... ...

    Abstract A 56-year old male with ischemic heart disease and an unremarkable preoperative echocardiogram underwent surgical coronary revascularization. An intraoperative post pump trans-esophageal echocardiogram (TOE) performed while the patient was being ventilated at a positive end expiratory pressure (PEEP) of 8 cm H
    Language English
    Publishing date 2017-08-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2605724-4
    ISSN 2039-7283 ; 2039-7275
    ISSN (online) 2039-7283
    ISSN 2039-7275
    DOI 10.4081/cp.2017.969
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  10. Article: Unveiling the Hidden Chamber: Exploring the Importance of Left Atrial Function and Filling Pressure in Cardiovascular Health.

    Pergola, Valeria / D'Andrea, Antonello / Galzerano, Domenico / Mantovani, Francesca / Rizzo, Massimiliano / Giannuario, Giovanna Di / Khoury, Georgette / Polizzi, Vincenzo / Rabia, Granit / Gimelli, Alessia / Campana, Marco

    Journal of cardiovascular echography

    2023  Volume 33, Issue 3, Page(s) 117–124

    Abstract: The left atrium (LA) is a vital component of the cardiovascular system, playing a crucial role in cardiac function. It acts as a reservoir, conduit, and contractile chamber, contributing to optimal left ventricle (LV) filling and cardiac output. ... ...

    Abstract The left atrium (LA) is a vital component of the cardiovascular system, playing a crucial role in cardiac function. It acts as a reservoir, conduit, and contractile chamber, contributing to optimal left ventricle (LV) filling and cardiac output. Abnormalities in LA function have been associated with various cardiovascular conditions, including heart failure, atrial fibrillation, valvular heart disease, and hypertension. Elevated left ventricular filling pressures resulting from impaired LA function can lead to diastolic dysfunction and increase the risk of adverse cardiovascular events. Understanding the relationship between LA function and LV filling pressures is crucial for comprehending the pathophysiology of cardiovascular diseases and guiding clinical management strategies. This article provides an overview of the anatomy and physiology of the LA, discusses the role of LA mechanics in maintaining normal cardiac function, highlights the clinical implications of elevated filling pressures, and explores diagnostic methods for assessing LA function and filling pressures. Furthermore, it discusses the prognostic implications and potential therapeutic approaches for managing patients with abnormal LA function and elevated filling pressure. Continued research and clinical focus on left atrial function are necessary to improve diagnostic accuracy, prognostic assessment, and treatment strategies in cardiovascular diseases. It will explore the importance of assessing LA function as a marker of cardiac performance and evaluate its implications for clinical practice. In accordance with rigorous scientific methodology, our search encompassed PubMed database. We selected articles deemed pertinent to our subject matter. Subsequently, we extracted and synthesized the salient contents, capturing the essence of each selected article.
    Language English
    Publishing date 2023-11-20
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/jcecho.jcecho_44_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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