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  1. Article: Introduction to focused issue on novel technologies in endocrine surgery.

    Barczyński, Marcin

    Gland surgery

    2020  Volume 9, Issue Suppl 2, Page(s) S65–S68

    Language English
    Publishing date 2020-03-02
    Publishing country China (Republic : 1949- )
    Document type Editorial
    ZDB-ID 3016969-0
    ISSN 2227-8575 ; 2227-684X
    ISSN (online) 2227-8575
    ISSN 2227-684X
    DOI 10.21037/gs.2020.01.10
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  2. Article ; Online: Invited Commentary: The Clinical Significance of Lymph Node Ratio and Ki-67 Expression in Papillary Thyroid Cancer.

    Barczyński, Marcin

    World journal of surgery

    2021  Volume 45, Issue 7, Page(s) 2165–2166

    MeSH term(s) Carcinoma, Papillary ; Humans ; Ki-67 Antigen ; Lymph Node Ratio ; Lymph Nodes ; Retrospective Studies ; Thyroid Cancer, Papillary/surgery ; Thyroid Neoplasms/surgery
    Chemical Substances Ki-67 Antigen
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-021-06087-3
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  3. Article ; Online: Current approach to surgical management of hyperthyroidism.

    Barczyński, Marcin

    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

    2021  Volume 65, Issue 2, Page(s) 124–131

    Abstract: Hyperthyroidism is a set of disorders that involve excess synthesis and secretion of thyroid hormones by the thyroid gland, which leads to thyrotoxicosis. The most common forms of hyperthyroidism include diffuse toxic goiter (Graves' disease), toxic ... ...

    Abstract Hyperthyroidism is a set of disorders that involve excess synthesis and secretion of thyroid hormones by the thyroid gland, which leads to thyrotoxicosis. The most common forms of hyperthyroidism include diffuse toxic goiter (Graves' disease), toxic multinodular goiter (Plummer disease), and a solitary toxic adenoma. The most reliable screening measure of thyroid function is the thyroid-stimulating hormone (TSH) level. Options for treatment of hyperthyroidism include: antithyroid drugs, radioactive iodine therapy (the preferred treatment of hyperthyroidism among US thyroid specialists), or thyroidectomy. Massive thyroid enlargement with compressive symptoms, a suspicious nodule, Graves' orbitopathy, and patient preference are indications for surgical treatment of thyrotoxicosis. This paper reviews the current literature and controversies on the surgical approach to the management of hyperthyroidism.
    MeSH term(s) Amiodarone/metabolism ; Antithyroid Agents/pharmacology ; Combined Modality Therapy ; Graves Disease/physiopathology ; Humans ; Hyperthyroidism/chemically induced ; Hyperthyroidism/drug therapy ; Hyperthyroidism/physiopathology ; Hyperthyroidism/surgery ; Iodine Radioisotopes/pharmacology ; Risk Factors ; Thyroid Gland ; Thyroid Hormones ; Thyroidectomy
    Chemical Substances Antithyroid Agents ; Iodine Radioisotopes ; Thyroid Hormones ; Amiodarone (N3RQ532IUT)
    Language English
    Publishing date 2021-01-26
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 1281687-5
    ISSN 1827-1936 ; 0392-0208 ; 1125-0135 ; 1824-4661 ; 1824-4785
    ISSN (online) 1827-1936
    ISSN 0392-0208 ; 1125-0135 ; 1824-4661 ; 1824-4785
    DOI 10.23736/S1824-4785.21.03330-6
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    Zs.A 18: Show issues Location:
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  4. Article ; Online: A Novel Approach to Continuous Monitoring of the Recurrent Laryngeal Nerve during Thyroid Surgery.

    Barczyński, Marcin

    Journal of investigative surgery : the official journal of the Academy of Surgical Research

    2020  Volume 34, Issue 9, Page(s) 1044–1045

    MeSH term(s) Humans ; Parathyroid Glands ; Recurrent Laryngeal Nerve ; Recurrent Laryngeal Nerve Injuries/etiology ; Recurrent Laryngeal Nerve Injuries/prevention & control ; Thyroid Gland/surgery ; Thyroidectomy/adverse effects
    Language English
    Publishing date 2020-03-18
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 639444-9
    ISSN 1521-0553 ; 0894-1939
    ISSN (online) 1521-0553
    ISSN 0894-1939
    DOI 10.1080/08941939.2020.1740361
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    Zs.A 2364: Show issues Location:
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  5. Article ; Online: Commentary on the study of Li J et al: The KWAK TI-RADS and 2015 ATA guidelines for medullary thyroid carcinoma, combined with cell block-assisted ultrasound-guided thyroid fine-needle aspiration.

    Barczyński, Marcin

    Clinical endocrinology

    2020  Volume 92, Issue 5, Page(s) 407–408

    MeSH term(s) Biopsy, Fine-Needle ; Humans ; Thyroid Neoplasms ; Thyroid Nodule ; Ultrasonography ; Ultrasonography, Interventional
    Language English
    Publishing date 2020-02-17
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 121745-8
    ISSN 1365-2265 ; 0300-0664
    ISSN (online) 1365-2265
    ISSN 0300-0664
    DOI 10.1111/cen.14165
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    Zs.A 814: Show issues Location:
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  6. Article ; Online: Clinical validation of NerveTrend versus conventional i-IONM mode of NIM Vital in prevention of recurrent laryngeal nerve events during bilateral thyroid surgery: A randomized controlled trial.

    Barczyński, Marcin / Konturek, Aleksander

    Head & neck

    2023  Volume 46, Issue 3, Page(s) 492–502

    Abstract: Background: The aim of this study was to test the hypothesis that use of NerveTrend™ mode of intermittent neuromonitoring (i-IONM) during thyroidectomy may identify and prevent impending recurrent laryngeal nerve (RLN) injury.: Methods: A randomized ... ...

    Abstract Background: The aim of this study was to test the hypothesis that use of NerveTrend™ mode of intermittent neuromonitoring (i-IONM) during thyroidectomy may identify and prevent impending recurrent laryngeal nerve (RLN) injury.
    Methods: A randomized clinical trial. The primary outcome was prevalence of RLN injury on postoperative day 1. In NerveTrend™ group the i-IONM stimulator was used for trending of amplitude and latency changes from initial vagal electromyographic baseline to tailor surgical strategy.
    Results: Some 264 patients were randomized into the intervention versus the control group, 132 patients each. RLN injury was found on postoperative day 1 in 5/264 (1.89%) nerves at risk (NAR) versus 12/258 (4.65%) NAR whereas staged thyroidectomy was used in 0/132 (0.00%) versus 6/132 (4.54%) patients (p = 0.067 and p = 0.029, respectively).
    Conclusion: The use of NerveTrend™ mode resulted in tendency towards reduced RLN injury on postoperative day 1 and significant decrease of need for a staged thyroidectomy.
    MeSH term(s) Humans ; Thyroid Gland ; Recurrent Laryngeal Nerve ; Monitoring, Intraoperative/methods ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Recurrent Laryngeal Nerve Injuries/etiology ; Recurrent Laryngeal Nerve Injuries/prevention & control ; Recurrent Laryngeal Nerve Injuries/epidemiology
    Language English
    Publishing date 2023-12-14
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27601
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    Zs.A 1493: Show issues Location:
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  7. Article ; Online: Commentary on the study of Walczyk et al. Poorly differentiated thyroid cancer in the context of the revised 2015 American Thyroid Association Guidelines and the Updated American Joint Committee on Cancer/Tumor-Node-Metastasis Staging System (eighth edition).

    Barczyński, Marcin

    Clinical endocrinology

    2019  Volume 91, Issue 2, Page(s) 245–246

    MeSH term(s) Humans ; Neoplasm Staging ; Neoplasms, Second Primary ; Thyroid Neoplasms ; United States
    Language English
    Publishing date 2019-05-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 121745-8
    ISSN 1365-2265 ; 0300-0664
    ISSN (online) 1365-2265
    ISSN 0300-0664
    DOI 10.1111/cen.14010
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  8. Article: Current Knowledge on the Use of Neuromonitoring in Thyroid Surgery.

    Wojtczak, Beata / Sutkowska-Stępień, Karolina / Głód, Mateusz / Kaliszewski, Krzysztof / Sutkowski, Krzysztof / Barczyński, Marcin

    Biomedicines

    2024  Volume 12, Issue 3

    Abstract: Thyroid surgery rates have tripled over the past three decades, making it one of the most frequently performed procedures within general surgery. Thyroid surgery is associated with the possibility of serious postoperative complications which have a ... ...

    Abstract Thyroid surgery rates have tripled over the past three decades, making it one of the most frequently performed procedures within general surgery. Thyroid surgery is associated with the possibility of serious postoperative complications which have a significant impact on the patient's quality of life. Recurrent laryngeal nerve (RLN) palsy and external branch of the superior laryngeal nerve (EBSLN) palsy are, next to hypoparathyroidism and postoperative bleeding, some of the most common complications. The introduction of neuromonitoring into thyroid surgery, which enabled both the confirmation of anatomical integrity and the assessment of laryngeal nerve function, was a milestone that began a new era in thyroid surgery. The International Neural Monitoring Study Group has produced a standardization of the technique of RLN and EBSLN monitoring during thyroid and parathyroid surgery, which in turn increased the prevalence of neural monitoring during thyroidectomy. The current status of IONM and the benefits of its use have been presented in this publication.
    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12030675
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  9. Article: Expression of micro-ribonucleic acids in thyroid nodules and serum to discriminate between follicular adenoma and cancer in patients with a fine needle aspiration biopsy classified as suspicious for follicular neoplasm: A preliminary study.

    Świrta, Jarosław Szymon / Wątor, Gracjan / Seweryn, Michał / Kapusta, Przemysław / Barczyński, Marcin / Wołkow, Paweł

    Advances in clinical and experimental medicine : official organ Wroclaw Medical University

    2023  Volume 32, Issue 9, Page(s) 997–1007

    Abstract: Background: Approximately 10% of thyroid nodules undergoing fine needle aspiration biopsy (FNAB) receive a suspicious for follicular neoplasm (SFN) classification. Currently, there is no diagnostic tool to preoperatively discriminate between follicular ... ...

    Abstract Background: Approximately 10% of thyroid nodules undergoing fine needle aspiration biopsy (FNAB) receive a suspicious for follicular neoplasm (SFN) classification. Currently, there is no diagnostic tool to preoperatively discriminate between follicular adenoma (FA) and thyroid cancer (TC), and most patients require surgery to exclude malignancy.
    Objectives: To characterize the micro-ribonucleic acid (miRNA) signature of tumors assessed as SFN and define circulating miRNA patterns to distinguish FA from follicular cancer in patients with thyroid nodules biopsied using FNAB.
    Material and methods: The study included excised tumor and thyroid tissue samples from 80 consecutive patients collected by a pathologist in the operating theater. The miRNA was isolated from specimens at the Center for Medical Genomics OMICRON, and next-generation sequencing (NGS) was used to obtain target miRNAs. In addition, miRNA expression was detected in serum using polymerase chain reaction (PCR).
    Results: Well-differentiated thyroid cancer (WDTC) samples had significantly higher expression levels of hsa-miR-146b-5p (p = 0.030) and hsa-miR-146b-3p (p = 0.032), while the expression levels of hsa-miR-195-3p were significantly lower (p = 0.032) in WDTC samples compared to FA specimens. The serum of TC patients showed markedly higher expression of the unique miRNA hsa-miR-195-3p (p = 0.039).
    Conclusions: The overexpression of hsa-miR-146b-5p and hsa-miR-146b-3p, and the downregulation of hsa-miR-195-3p expression could be used as biomarkers to distinguish FA from WDTC in patients with FNAB results classified as Bethesda tier IV. In addition, hsa-miR-195-3p could act as a serum biomarker for differentiating patients with FA from those with WDTC, and preoperative measurement of its expression would help avoid unnecessary surgeries. However, this concept needs further verification in a more substantial prospective study.
    MeSH term(s) Humans ; Thyroid Nodule/diagnosis ; Thyroid Nodule/genetics ; Thyroid Nodule/pathology ; Biopsy, Fine-Needle/methods ; Prospective Studies ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/genetics ; MicroRNAs/metabolism ; Adenoma/diagnosis ; Adenoma/genetics
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2023-09-20
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2270257-X
    ISSN 1899-5276 ; 1230-025X
    ISSN 1899-5276 ; 1230-025X
    DOI 10.17219/acem/160003
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  10. Article ; Online: Intention to treat analysis: are we really doing it? Reply.

    Barczyński, Marcin

    World journal of surgery

    2013  Volume 37, Issue 5, Page(s) 1183–1184

    MeSH term(s) Female ; Goiter/surgery ; Humans ; Laryngeal Nerve Injuries/prevention & control ; Monitoring, Intraoperative ; Thyroidectomy/adverse effects ; Voice Disorders/prevention & control
    Language English
    Publishing date 2013-03-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-013-1984-y
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