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  1. Article ; Online: Is the APEX Score the Pinnacle of Predictive Scoring Systems of Disease Flare in Crohn's Patients with Documented Mucosal Healing?

    Tsiaoussis, Georgios I / Christaki, Eirini

    Digestive diseases and sciences

    2021  Volume 67, Issue 4, Page(s) 1092–1094

    MeSH term(s) Crohn Disease/diagnosis ; Humans ; Infliximab ; Intestinal Mucosa/diagnostic imaging ; Symptom Flare Up ; Wound Healing
    Chemical Substances Infliximab (B72HH48FLU)
    Language English
    Publishing date 2021-07-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-021-07154-4
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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Gut Microbiota Modulation and Prevention of Dysbiosis as an Alternative Approach to Antimicrobial Resistance: A Narrative Review.

    Matzaras, Rafail / Nikopoulou, Anna / Protonotariou, Efthimia / Christaki, Eirini

    The Yale journal of biology and medicine

    2022  Volume 95, Issue 4, Page(s) 479–494

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Humans ; Gastrointestinal Microbiome ; Anti-Bacterial Agents/pharmacology ; Dysbiosis/drug therapy ; Dysbiosis/microbiology ; Drug Resistance, Bacterial ; Probiotics/pharmacology ; Probiotics/therapeutic use ; Fecal Microbiota Transplantation
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-12-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 200515-3
    ISSN 1551-4056 ; 0044-0086
    ISSN (online) 1551-4056
    ISSN 0044-0086
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  3. Article ; Online: The Role of Probiotics in Inflammation Associated with Major Surgery: A Narrative Review.

    Matzaras, Rafail / Anagnostou, Nikolaos / Nikopoulou, Anna / Tsiakas, Ilias / Christaki, Eirini

    Nutrients

    2023  Volume 15, Issue 6

    Abstract: Background: Gut microbiota is well-known for its ability to maintain intestinal homeostasis. However, the disruption of this homeostasis, known as dysbiosis, leads to multiple consequences, including local and systemic inflammation. Surgery-induced ... ...

    Abstract Background: Gut microbiota is well-known for its ability to maintain intestinal homeostasis. However, the disruption of this homeostasis, known as dysbiosis, leads to multiple consequences, including local and systemic inflammation. Surgery-induced inflammation is a major concern for patients, as it leads to many infectious and non-infectious complications.
    Objective: The purpose of this review was to explore the role of probiotics and symbiotics in surgery-induced inflammation and to determine if their use is effective in combatting inflammation and its complications Methods and Materials: A literature search was conducted, and articles published only in English, until December 2022 were included. The results are reported in the form of a narrative review.
    Results: The perioperative use of probiotics and/or symbiotics results in lower risk of infectious complications, including reduced rates of surgical site infections, respiratory and urinary tract infections, shorter hospital stays, and fewer days of antibiotic administration. It also contributes to reducing non-infectious complications, as it mitigates systemic and local inflammation via maintenance of the intestinal barrier, improves intestinal mobility, and is associated with lower rates of postoperative pain and anastomotic leak.
    Conclusions: Restoring gut microbiota after disruptions caused by surgery may accelerate local healing processes, attenuate systemic inflammation, and may thus prove beneficial to certain populations.
    MeSH term(s) Humans ; Inflammation ; Intestines ; Probiotics ; Gastrointestinal Microbiome ; Dysbiosis
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15061331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pityriasis Rosea Induced by COVID-19 Vaccination.

    Khattab, Elina / Christaki, Eirini / Pitsios, Constantinos

    European journal of case reports in internal medicine

    2022  Volume 9, Issue 2, Page(s) 3164

    Abstract: It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. ... ...

    Abstract It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. We present two cases of COVID-19 vaccine-induced pityriasis rosea. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. The exanthem was self-limited in both patients over a period of a month.
    Learning points: Physicians should be aware that pityriasis rosea is a rare side-effect of COVID-19 vaccination.Pityriasis rosea is self-limiting and no medical treatment is usually required.
    Language English
    Publishing date 2022-02-03
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2022_003164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pityriasis Rosea Induced by COVID-19 Vaccination

    Elina Khattab / Eirini Christaki / Constantinos Pitsios

    European Journal of Case Reports in Internal Medicine (2022)

    2022  

    Abstract: It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. ... ...

    Abstract It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. We present two cases of COVID-19 vaccine-induced pityriasis rosea. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. The exanthem was self-limited in both patients over a period of a month.
    Keywords covid-19 ; sars-cov-2 ; vaccination ; pityriasis rosea ; Medicine ; R
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Recurrent

    Pieta, Antigone / Venetsanopoulou, Aliki I / Kittas, Christos / Christaki, Eirini / Voulgari, Paraskevi V

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 6

    Abstract: Rheumatoid arthritis (RA) patients deal with a higher risk of bacterial and fungal infections compared to the general population because of their dysregulated immune system as well as the immunosuppressive therapy they usually receive. ...

    Abstract Rheumatoid arthritis (RA) patients deal with a higher risk of bacterial and fungal infections compared to the general population because of their dysregulated immune system as well as the immunosuppressive therapy they usually receive.
    Language English
    Publishing date 2023-06-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9060683
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  7. Article ; Online: New technologies in predicting, preventing and controlling emerging infectious diseases.

    Christaki, Eirini

    Virulence

    2015  Volume 6, Issue 6, Page(s) 558–565

    Abstract: Surveillance of emerging infectious diseases is vital for the early identification of public health threats. Emergence of novel infections is linked to human factors such as population density, travel and trade and ecological factors like climate change ... ...

    Abstract Surveillance of emerging infectious diseases is vital for the early identification of public health threats. Emergence of novel infections is linked to human factors such as population density, travel and trade and ecological factors like climate change and agricultural practices. A wealth of new technologies is becoming increasingly available for the rapid molecular identification of pathogens but also for the more accurate monitoring of infectious disease activity. Web-based surveillance tools and epidemic intelligence methods, used by all major public health institutions, are intended to facilitate risk assessment and timely outbreak detection. In this review, we present new methods for regional and global infectious disease surveillance and advances in epidemic modeling aimed to predict and prevent future infectious diseases threats.
    MeSH term(s) Communicable Disease Control/methods ; Communicable Disease Control/organization & administration ; Communicable Diseases, Emerging/diagnosis ; Communicable Diseases, Emerging/epidemiology ; Disease Transmission, Infectious/prevention & control ; Epidemiological Monitoring ; Humans
    Keywords covid19
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2657572-3
    ISSN 2150-5608 ; 2150-5594
    ISSN (online) 2150-5608
    ISSN 2150-5594
    DOI 10.1080/21505594.2015.1040975
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  8. Article: Factors Associated with Extended-Spectrum β-Lactamases and Carbapenem-Resistant

    Tofarides, Andreas G / Dimitriou, Panagiotis / Nikolopoulos, Georgios K / Rogkas, Dimitrios / Flourou, Christina / Khattab, Elina / Kasapi, Diamanto / Azina, Chara / Christaki, Eirini

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 11

    Abstract: Klebsiella ... ...

    Abstract Klebsiella pneumoniae
    Language English
    Publishing date 2023-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12111277
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  9. Article ; Online: Personalized medicine in sepsis: the coming of age.

    Christaki, Eirini

    Expert review of anti-infective therapy

    2013  Volume 11, Issue 7, Page(s) 645–647

    MeSH term(s) Biomarkers/blood ; Disease Susceptibility ; Early Diagnosis ; Humans ; Precision Medicine/trends ; Prognosis ; Sepsis/diagnosis ; Sepsis/drug therapy ; Treatment Outcome
    Chemical Substances Biomarkers
    Language English
    Publishing date 2013-07
    Publishing country England
    Document type Editorial
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1586/14787210.2013.811845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effect of Vaccination against SARS-CoV-2 on Long COVID-19: A Narrative Review.

    Tofarides, Andreas G / Christaki, Eirini / Milionis, Haralampos / Nikolopoulos, Georgios K

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 12

    Abstract: Vaccines against SARS-CoV-2 have saved millions of lives and played an important role in containing the COVID-19 pandemic. Vaccination against SARS-CoV-2 is also associated with reduced disease severity and, perhaps, with COVID-19 symptom burden. In this ...

    Abstract Vaccines against SARS-CoV-2 have saved millions of lives and played an important role in containing the COVID-19 pandemic. Vaccination against SARS-CoV-2 is also associated with reduced disease severity and, perhaps, with COVID-19 symptom burden. In this narrative review, we present, in a clinically relevant question-and-answer manner, the evidence regarding the association between vaccination against SARS-CoV-2 and long COVID-19. We discuss how the mechanism of action of vaccines could interplay with the pathophysiology of post-COVID-19 condition. Furthermore, we describe how specific factors, such as the number of vaccine doses and the type of SARS-CoV-2 variants, may affect post-COVID-19 condition. We also discuss the role of timing for vaccination in relation to the onset of long COVID-19 symptoms, as it seems to affect the frequency and severity of the condition. Additionally, we describe the potential modifying effect of age, as well as the association of type and level of immune response with long COVID-19. We also describe how system-specific long COVID-19 sequelae, namely neurocognitive-psychologic symptoms and cardiovascular pathology, could be altered by vaccination. Last, we address the question of whether seasonal influenza vaccination has a meaningful impact on the frequency of long COVID-19.
    Language English
    Publishing date 2022-12-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12122057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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