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  1. Article ; Online: Pioneers in Dermatology and Venereology: An Interview with Professor An Goossens.

    Goossens, An

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2022  Volume 37, Issue 3, Page(s) 469–471

    MeSH term(s) Humans ; Venereology/history ; Dermatology/history
    Language English
    Publishing date 2022-10-12
    Publishing country England
    Document type Interview
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.18878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Consort allergic contact dermatitis due to propolis in eardrops.

    Stefan, Kerre / An, Goossens

    Contact dermatitis

    2023  Volume 90, Issue 2, Page(s) 189–190

    MeSH term(s) Humans ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Propolis/adverse effects ; Patch Tests ; Ascomycota
    Chemical Substances Propolis (9009-62-5)
    Language English
    Publishing date 2023-10-26
    Publishing country England
    Document type Case Reports
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Contact allergy to and allergic contact dermatitis from formaldehyde and formaldehyde releasers: A clinical review and update.

    Goossens, An / Aerts, Olivier

    Contact dermatitis

    2022  Volume 87, Issue 1, Page(s) 20–27

    Abstract: This review aims to provide a clinically useful update regarding the role of formaldehyde (FA) and its five main releasers (FRs) quaternium-15, diazolidinyl urea, DMDM hydantoin, imidazolidinyl urea, and 2-bromo-2-nitropropane-1,3-diol (bronopol) in ... ...

    Abstract This review aims to provide a clinically useful update regarding the role of formaldehyde (FA) and its five main releasers (FRs) quaternium-15, diazolidinyl urea, DMDM hydantoin, imidazolidinyl urea, and 2-bromo-2-nitropropane-1,3-diol (bronopol) in contact allergy and allergic contact dermatitis. These ubiquitous preservatives are still often present, and sometimes undeclared, in cosmetics, pharmaceuticals, medical devices, household detergents, and chemical (industrial) products. In Europe, the use of free FA and quaternium-15 in cosmetics is forbidden and contact allergy rates have been found to be stable to decreasing. However, FA/FRs still readily provoke localized (eg, facial/hand), airborne, and generalized dermatitis, and may also complicate atopic and stasis dermatitis, or result in nummular dermatitis. Seborrheic-, rosacea- and impetigo-like dermatitis have recently been reported. For a correct diagnosis, FA 2% aq. (0.60 mg/cm
    MeSH term(s) Cosmetics/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Formaldehyde/adverse effects ; Humans ; Patch Tests/adverse effects ; Preservatives, Pharmaceutical
    Chemical Substances Cosmetics ; Preservatives, Pharmaceutical ; Formaldehyde (1HG84L3525)
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Allergic contact dermatitis from a medical device containing Picea abies (Norway spruce) resin: Skin sensitizers other than resin acids might be of importance.

    Dendooven, Ella / Kerre, Stefan / Goossens, An / Aerts, Olivier

    Contact dermatitis

    2022  

    Language English
    Publishing date 2022-09-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cosmetic Contact Allergens

    An Goossens

    Cosmetics, Vol 3, Iss 1, p

    2016  Volume 5

    Abstract: This article presents trends in the frequency of cosmetics as causal factors of allergic contact dermatitis during a 26-year period in 14,911 patients patch-tested between 1990 and 2014, and discusses the cosmetic allergens identified during the last six ...

    Abstract This article presents trends in the frequency of cosmetics as causal factors of allergic contact dermatitis during a 26-year period in 14,911 patients patch-tested between 1990 and 2014, and discusses the cosmetic allergens identified during the last six years (2010–2015) in 603 patients out of 3105 tested. The data were retrieved from, and evaluated with, a patient database developed in-house. The results show the increasing importance of cosmetic allergies, up to 25% of the patients tested during the last five-year period. As expected, fragrance materials, preservatives, and hair dyes were the most frequent culprits, but a great variety of other allergenic ingredients were involved as well. This underlines the need of additional and extensive patch testing with the patient’s products used and their ingredients.
    Keywords allergens ; allergic contact dermatitis ; cosmetics ; fragrances ; preservatives ; ingredients ; Chemistry ; QD1-999
    Language English
    Publishing date 2016-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Occupational airborne allergic contact dermatitis to linalyl acetate in a disinfectant spray.

    White, Jonathan M L / Goossens, An

    Contact dermatitis

    2020  Volume 83, Issue 5, Page(s) 412–413

    MeSH term(s) Adult ; Air Pollutants, Occupational/adverse effects ; Allergens/adverse effects ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Occupational/etiology ; Disinfectants/adverse effects ; Edema/chemically induced ; Female ; Humans ; Male ; Monoterpenes/adverse effects ; Patch Tests/methods ; Plant Oils/adverse effects
    Chemical Substances Air Pollutants, Occupational ; Allergens ; Disinfectants ; Monoterpenes ; Plant Oils ; linalyl acetate (5K47SSQ51G)
    Language English
    Publishing date 2020-05-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: New Cosmetic Contact Allergens

    An Goossens

    Cosmetics, Vol 2, Iss 1, Pp 22-

    2015  Volume 32

    Abstract: Allergic and photo-allergic contact dermatitis, and immunologic contact urticaria are potential immune-mediated adverse effects from cosmetics. Fragrance components and preservatives are certainly the most frequently observed allergens; however, all ... ...

    Abstract Allergic and photo-allergic contact dermatitis, and immunologic contact urticaria are potential immune-mediated adverse effects from cosmetics. Fragrance components and preservatives are certainly the most frequently observed allergens; however, all ingredients must be considered when investigating for contact allergy.
    Keywords allergic contact dermatitis ; contact urticaria ; cosmetics ; fragrances ; preservatives ; Chemistry ; QD1-999
    Language English
    Publishing date 2015-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Iatrogenic allergic contact dermatitis in the (peri)anal and genital area.

    Gilissen, Liesbeth / Schollaert, Isabelle / Huygens, Sara / Goossens, An

    Contact dermatitis

    2021  Volume 84, Issue 6, Page(s) 431–438

    Abstract: Background: Allergic contact dermatitis (ACD) from topical medication often occurs in occluded areas, for example, with wound treatment, but also in certain body locations, such as the anogenital area.: Objectives: To investigate the demographics and ...

    Abstract Background: Allergic contact dermatitis (ACD) from topical medication often occurs in occluded areas, for example, with wound treatment, but also in certain body locations, such as the anogenital area.
    Objectives: To investigate the demographics and specific lesion location of patients with ACD from topical drugs applied onto the (peri)anal/genital area, and to identify the respective causal topical pharmaceutical products and ingredients involved.
    Methods: From January 2000 to December 10, 2018, 532 patients were tested with the baseline series, sometimes with additional series, and the topical medication used along with the ingredients. The relevant data were extracted from our electronic databases developed in-house.
    Results: Forty-four patients (9%) out of 473 patients suffering from lesions in the (peri)anal/genital area had positive patch test results to topical drug preparations and/or their ingredients, sometimes in association with cosmetics for intimate hygiene. The most frequent sensitizing active principles were local anaesthetics and corticosteroids, while wool alcohols and to a minor extent benzoic acid were the most frequent culprits among the vehicle components and preservative agents, respectively.
    Conclusions: The local conditions (eg, occlusion, sweating, moist) in the anogenital area may favour skin sensitization to topical medication used to treat various skin diseases.
    MeSH term(s) Adolescent ; Adrenal Cortex Hormones/adverse effects ; Adult ; Aged ; Anesthetics, Local/adverse effects ; Anus Diseases/chemically induced ; Benzoic Acid/adverse effects ; Child ; Child, Preschool ; Cosmetics/adverse effects ; Dermatitis, Allergic Contact/etiology ; Female ; Genital Diseases, Female/chemically induced ; Genital Diseases, Male/chemically induced ; Humans ; Hygiene ; Infant ; Lanolin/adverse effects ; Male ; Middle Aged ; Preservatives, Pharmaceutical/adverse effects ; Retrospective Studies ; Young Adult
    Chemical Substances Adrenal Cortex Hormones ; Anesthetics, Local ; Cosmetics ; Preservatives, Pharmaceutical ; Lanolin (8006-54-0) ; Benzoic Acid (8SKN0B0MIM)
    Language English
    Publishing date 2021-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The need to disclose the composition of medical devices at the European level.

    Herman, Anne / Goossens, An

    Contact dermatitis

    2019  Volume 81, Issue 3, Page(s) 159–160

    MeSH term(s) Dermatitis, Allergic Contact/etiology ; Disclosure/legislation & jurisprudence ; Equipment and Supplies/adverse effects ; European Union ; Humans ; Manufacturing Industry/legislation & jurisprudence
    Language English
    Publishing date 2019-07-16
    Publishing country England
    Document type Editorial
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reducing Campylobacter colonization in broilers by active immunization of naive broiler breeders using a bacterin and subunit vaccine.

    Haems, Kristof / Van Rysselberghe, Nathalie / Goossens, Evy / Strubbe, Diederik / Rasschaert, Geertrui / Martel, An / Pasmans, Frank / Garmyn, An

    Poultry science

    2023  Volume 102, Issue 12, Page(s) 103075

    Abstract: Campylobacter is the main cause of human gastroenteritis worldwide, with 50 to 80% of the cases related to consumption of poultry products. Maternal antibodies (MAB) from commercial breeder flocks may protect their progeny against infection during the ... ...

    Abstract Campylobacter is the main cause of human gastroenteritis worldwide, with 50 to 80% of the cases related to consumption of poultry products. Maternal antibodies (MAB) from commercial breeder flocks may protect their progeny against infection during the first few weeks of life. We here studied the prevalence of Campylobacter antibody titers in broiler breeder flocks and to which extent immunization of broiler breeders increases maternal anti-Campylobacter titers in their progeny and protects the offspring against Campylobacter colonization. Two vaccines were used: a bacterin mix of 13 Campylobacter strains and a subunit vaccine comprising 6 immunodominant Campylobacter antigens. All sampled on-farm breeder flocks were positive for anti-Campylobacter antibodies, yet in some breeder flocks only very low titers were detected. Vaccination of SPF broiler breeder flocks with both subunit and bacterin vaccines resulted in a prolonged presence of anti-Campylobacter antibodies in the serum and intestinal mucus of chicks. These bacterin- or subunit vaccine-induced MAB conferred protection against Campylobacter colonization in chicks until 7 and 21 d of age, respectively, but only at a low challenge dose (10
    MeSH term(s) Animals ; Humans ; Chickens ; Bacterial Vaccines ; Campylobacter ; Antibodies ; Campylobacter Infections/prevention & control ; Campylobacter Infections/veterinary ; Vaccination/veterinary ; Vaccination/methods ; Vaccines, Subunit ; Poultry Diseases/prevention & control ; Poultry Diseases/epidemiology
    Chemical Substances Bacterial Vaccines ; Antibodies ; Vaccines, Subunit
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2023.103075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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