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  1. Article ; Online: Aspartate aminotransferase: A prognostic marker rather than a specific liver injury marker in COVID-19.

    Li, Gerui

    The Journal of infection

    2020  Volume 81, Issue 2, Page(s) e155

    MeSH term(s) Aspartate Aminotransferases ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Liver ; Pandemics ; Pneumonia, Viral ; Prognosis ; SARS-CoV-2
    Chemical Substances Aspartate Aminotransferases (EC 2.6.1.1)
    Keywords covid19
    Language English
    Publishing date 2020-06-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.06.007
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1501: Show issues Location:
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  2. Article ; Online: Inpatient use of glucocorticoids may mediate the detrimental effect of new-onset hyperglycemia on COVID-19 severity.

    Li, Gerui

    Diabetes research and clinical practice

    2020  Volume 168, Page(s) 108441

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Diabetes Mellitus ; Glucocorticoids/adverse effects ; Humans ; Hyperglycemia/chemically induced ; Hyperglycemia/epidemiology ; Inpatients ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Glucocorticoids
    Keywords covid19
    Language English
    Publishing date 2020-09-12
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2020.108441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2047: Show issues Location:
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  5. Article ; Online: Aspartate aminotransferase

    Li, Gerui

    Journal of Infection

    A prognostic marker rather than a specific liver injury marker in COVID-19

    2020  Volume 81, Issue 2, Page(s) e155

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.06.007
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Progress in research on the molecular biological detection techniques of avian encephalomyelitis.

    Zhang, Gerui / Li, Shuguang / Shen, Zhiqiang / Wang, Fangkun

    Research in veterinary science

    2023  Volume 159, Page(s) 232–236

    Abstract: Avian encephalomyelitis (AE) is a highly infectious disease caused by the avian encephalomyelitis virus (AEV), which primarily affects the central nervous system of 1- to 4-week-old chicks and causes significant economic losses in the worldwide poultry ... ...

    Abstract Avian encephalomyelitis (AE) is a highly infectious disease caused by the avian encephalomyelitis virus (AEV), which primarily affects the central nervous system of 1- to 4-week-old chicks and causes significant economic losses in the worldwide poultry industry. Despite heavy dependency on vaccine immunization, AEV has persisted on farms for extended periods, which increases its virulence and makes quick and accurate detection crucial to preventing and controlling the disease. Classical diagnostic methods have been unable to meet the current requirements for rapid diagnosis of AE cases. To address this issue, this paper reviews the etiological and molecular biological detection techniques of AE, and it seeks to provide a reference for future research and to establish differential diagnostic techniques for AE epidemiological investigation, identification of epidemic strains, and early diagnosis of clinical cases. Through improving our understanding of AE, we can better combat the disease and protect the global poultry industry.
    MeSH term(s) Animals ; Poultry Diseases/prevention & control ; Chickens ; Picornaviridae Infections/veterinary ; Encephalomyelitis Virus, Avian ; Encephalitis, Viral/veterinary ; Encephalomyelitis/veterinary
    Language English
    Publishing date 2023-04-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 840961-4
    ISSN 1532-2661 ; 0034-5288
    ISSN (online) 1532-2661
    ISSN 0034-5288
    DOI 10.1016/j.rvsc.2023.04.005
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    Zs.B 673: Show issues Location:
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  7. Article ; Online: Inpatient use of glucocorticoids may mediate the detrimental effect of new-onset hyperglycemia on COVID-19 severity

    Li, Gerui

    Diabetes Research and Clinical Practice

    2020  Volume 168, Page(s) 108441

    Keywords Internal Medicine ; Endocrinology, Diabetes and Metabolism ; Endocrinology ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2020.108441
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

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  8. Article: Identification of ribosomal protein family as immune-cell-related biomarkers of NAFLD by bioinformatics and experimental analyses.

    Li, Gerui / Li, Hang / Chen, Ze

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1161269

    Abstract: Background: Immune cells play an integral role in the development and progression of non-alcoholic fatty liver disease (NAFLD). This study was to identify immune-cell-related biomarkers for the diagnosis and treatment of NAFLD.: Methods and findings: ...

    Abstract Background: Immune cells play an integral role in the development and progression of non-alcoholic fatty liver disease (NAFLD). This study was to identify immune-cell-related biomarkers for the diagnosis and treatment of NAFLD.
    Methods and findings: First, we introduced human liver transcriptome data from the GEO database (GSE48452 and GSE126848) and performed a weighted gene co-expression network analysis (WGCNA) to screen out the modules related to immune cell infiltration and to identify immune-cell-related differentially expressed genes (ICR-DEGs) associated with NAFLD progression. Further, the protein-protein interaction (PPI) network of ICR-DEGs was established to obtain hub genes and subsequently, the expression trend analysis was conducted to identify immune-cell-related biomarkers of NAFLD. Finally, the mRNA expression of biomarkers was validated in a NAFLD mouse model induced by high-fat diet (HFD) feeding. In total, we identified 66 ICR-DEGs and 13 hub genes associated with NAFLD. Among them, 9 hub genes (
    Conclusions: This study identified four ribosomal protein genes (
    MeSH term(s) Humans ; Animals ; Mice ; Mice, Inbred ICR ; Ribosomal Proteins ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/genetics ; Biomarkers ; Computational Biology ; RNA, Messenger
    Chemical Substances Ribosomal Proteins ; Biomarkers ; RNA, Messenger
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1161269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Progress in research on the molecular biological detection techniques of avian encephalomyelitis

    Zhang, Gerui / Li, Shuguang / Shen, Zhiqiang / Wang, Fangkun

    Research in Veterinary Science. 2023 June, v. 159 p.232-236

    2023  

    Abstract: Avian encephalomyelitis (AE) is a highly infectious disease caused by the avian encephalomyelitis virus (AEV), which primarily affects the central nervous system of 1- to 4-week-old chicks and causes significant economic losses in the worldwide poultry ... ...

    Abstract Avian encephalomyelitis (AE) is a highly infectious disease caused by the avian encephalomyelitis virus (AEV), which primarily affects the central nervous system of 1- to 4-week-old chicks and causes significant economic losses in the worldwide poultry industry. Despite heavy dependency on vaccine immunization, AEV has persisted on farms for extended periods, which increases its virulence and makes quick and accurate detection crucial to preventing and controlling the disease. Classical diagnostic methods have been unable to meet the current requirements for rapid diagnosis of AE cases. To address this issue, this paper reviews the etiological and molecular biological detection techniques of AE, and it seeks to provide a reference for future research and to establish differential diagnostic techniques for AE epidemiological investigation, identification of epidemic strains, and early diagnosis of clinical cases. Through improving our understanding of AE, we can better combat the disease and protect the global poultry industry.
    Keywords Tremovirus A ; birds ; central nervous system ; early diagnosis ; encephalitis ; epidemiological studies ; immunization ; infectious diseases ; poultry industry ; research ; vaccines ; veterinary medicine ; virulence ; AEV ; Detection technology ; Etiology ; Infectious disease ; Poultry
    Language English
    Dates of publication 2023-06
    Size p. 232-236.
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 840961-4
    ISSN 1532-2661 ; 0034-5288
    ISSN (online) 1532-2661
    ISSN 0034-5288
    DOI 10.1016/j.rvsc.2023.04.005
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 2292: Show issues

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  10. Article ; Online: A novel antidiuretic hormone governs tumour-induced renal dysfunction.

    Xu, Wenhao / Li, Gerui / Chen, Yuan / Ye, Xujun / Song, Wei

    Nature

    2023  Volume 624, Issue 7991, Page(s) 425–432

    Abstract: Maintenance of renal function and fluid transport are essential for vertebrates and invertebrates to adapt to physiological and pathological challenges. Human patients with malignant tumours frequently develop detrimental renal dysfunction and oliguria, ... ...

    Abstract Maintenance of renal function and fluid transport are essential for vertebrates and invertebrates to adapt to physiological and pathological challenges. Human patients with malignant tumours frequently develop detrimental renal dysfunction and oliguria, and previous studies suggest the involvement of chemotherapeutic toxicity and tumour-associated inflammation
    MeSH term(s) Animals ; Humans ; Mice ; Antidiuretic Agents/metabolism ; Cyclic GMP/metabolism ; Disease Models, Animal ; Drosophila melanogaster/cytology ; Drosophila melanogaster/metabolism ; Kidney Diseases/complications ; Kidney Diseases/drug therapy ; Kidney Diseases/metabolism ; Malpighian Tubules/cytology ; Malpighian Tubules/metabolism ; Neoplasms/complications ; Neoplasms/metabolism ; Nitric Oxide Synthase/metabolism ; Receptors, Neurokinin-3/antagonists & inhibitors ; Receptors, Neurokinin-3/metabolism ; Xenograft Model Antitumor Assays ; Arginine Vasopressin/metabolism ; Drosophila Proteins/metabolism ; Neuropeptides/metabolism
    Chemical Substances Antidiuretic Agents ; Cyclic GMP (H2D2X058MU) ; Nitric Oxide Synthase (EC 1.14.13.39) ; Receptors, Neurokinin-3 ; TkR99D protein, Drosophila ; Arginine Vasopressin (113-79-1) ; Drosophila Proteins ; Neuropeptides
    Language English
    Publishing date 2023-12-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-023-06833-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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