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  1. Book ; Online: Handbook on cerebral venous thrombosis

    Caso, Valeria

    a timely and helpful clinical guide to a better understanding of CVT

    2008  

    Author's details vol. ed.: V. Caso
    Language English
    Size VI + 184 S.
    Publisher Karger
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Online
    HBZ-ID TT050388163
    ISBN 978-3-8055-8379-4 ; 3-8055-8379-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Handbook of cerebral venous thrombosis

    Caso, Valeria

    21 tables

    (Frontiers of neurology and neuroscience ; 23)

    2008  

    Author's details vol. ed. V. Caso
    Series title Frontiers of neurology and neuroscience ; 23
    Collection
    Keywords Intracranial Thrombosis / diagnosis ; Intracranial Thrombosis / radiotherapy ; Sinus Thrombosis, Intracranial / diagnosis ; Sinus Thrombosis, Intracranial / radiotherapy ; Sinusthrombose
    Subject Sinusvenenthrombose
    Language English
    Size VI, 184 S. : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT015393172
    ISBN 978-3-8055-8378-7 ; 3-8055-8378-8
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Editorial: Coronavirus disease 2019 and stroke: how to avoid a new lockdown for stroke patients.

    Caso, Valeria

    Current opinion in neurology

    2020  Volume 34, Issue 1, Page(s) 1–2

    MeSH term(s) COVID-19 ; Communicable Disease Control ; Humans ; Pandemics ; Stroke
    Language English
    Publishing date 2020-12-05
    Publishing country England
    Document type Editorial
    ZDB-ID 1182686-1
    ISSN 1473-6551 ; 1350-7540
    ISSN (online) 1473-6551
    ISSN 1350-7540
    DOI 10.1097/WCO.0000000000000892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ESO EAST Editorial.

    Caso, Valeria / Tsivgoulis, Georgios / Norrving, Bo

    European stroke journal

    2023  Volume 8, Issue 1 Suppl, Page(s) 3–4

    MeSH term(s) Membrane Proteins ; Antigens, Neoplasm
    Chemical Substances Membrane Proteins ; Antigens, Neoplasm
    Language English
    Publishing date 2023-02-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2851287-X
    ISSN 2396-9881 ; 2396-9873
    ISSN (online) 2396-9881
    ISSN 2396-9873
    DOI 10.1177/23969873221148632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hydroxyapatite Nanorods Based Drug Delivery Systems for Bumetanide and Meloxicam, Poorly Water Soluble Active Principles.

    Friuli, Valeria / Maggi, Lauretta / Bruni, Giovanna / Caso, Francesca / Bini, Marcella

    Nanomaterials (Basel, Switzerland)

    2024  Volume 14, Issue 1

    Abstract: Poorly water-soluble drugs represent a challenge for the pharmaceutical industry because it is necessary to find properly tuned and efficient systems for their release. In this framework, organic-inorganic hybrid systems could represent a promising ... ...

    Abstract Poorly water-soluble drugs represent a challenge for the pharmaceutical industry because it is necessary to find properly tuned and efficient systems for their release. In this framework, organic-inorganic hybrid systems could represent a promising strategy. A largely diffused inorganic host is hydroxyapatite (HAP, Ca
    Language English
    Publishing date 2024-01-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14010113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lessons to be learned in intracerebral haemorrhage research.

    Caso, Valeria / Mosconi, Maria Giulia

    The Lancet. Neurology

    2021  Volume 20, Issue 10, Page(s) 779–780

    MeSH term(s) Cerebral Hemorrhage ; Humans ; Learning
    Language English
    Publishing date 2021-09-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2081241-3
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(21)00296-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Service delivery in acute ischemic stroke patients: Does sex matter?

    Medlin, Friedrich / Strambo, Davide / Lambrou, Dimitris / Caso, Valeria / Michel, Patrik

    European journal of neurology

    2024  , Page(s) e16287

    Abstract: Background and purpose: Women with acute ischemic stroke (AIS) are older and have greater preexisting handicap than men. Given that these factors do not fully explain their poorer long-term outcomes, we sought to investigate potential sex differences in ...

    Abstract Background and purpose: Women with acute ischemic stroke (AIS) are older and have greater preexisting handicap than men. Given that these factors do not fully explain their poorer long-term outcomes, we sought to investigate potential sex differences in the delivery of acute stroke care in a large cohort of consecutive AIS patients.
    Methods: We analyzed all patients from ASTRAL (Acute Stroke Registry and Analysis of Lausanne) from March 2003 to December 2019. Multivariable analyses were performed on acute time metrics, revascularization therapies, ancillary examinations for stroke workup, subacute symptomatic carotid artery revascularization, frequency of change in goals of care (palliative care), and length of hospital stay.
    Results: Of the 5347 analyzed patients, 45% were biologically female and the median age was 74.6 years. After multiple adjustments, female sex was significantly associated with higher onset-to-door (adjusted hazard ratio [aHR] = 1.09, 95% confidence interval [CI] = 1.04-1.14) and door-to-endovascular-puncture intervals (aHR = 1.15, 95% CI = 1.05-1.25). Women underwent numerically fewer diagnostic examinations (adjusted odds ratio [aOR] = 0.94, 95% CI = 0.85-1.04) and fewer subacute carotid revascularizations (aOR = 0.69, 95% CI = 0.33-1.18), and had longer hospital stays (aHR = 1.03, 95% CI = 0.99-1.07), but these differences were not statistically significant. We found no differences in the rates of acute revascularization treatments, or in the frequency of change of goals of treatments.
    Conclusions: This retrospective analysis of a large, consecutive AIS cohort suggests that female sex is associated with unfavorable pre- and in-hospital time metrics, such as a longer onset-to-door and door-to-endovascular-puncture intervals. Such indicators of less effective stroke care delivery may contribute to the poorer long-term functional outcomes in female patients and require further attention.
    Language English
    Publishing date 2024-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.16287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hydroxyapatite Nanorods Based Drug Delivery Systems for Bumetanide and Meloxicam, Poorly Water Soluble Active Principles

    Valeria Friuli / Lauretta Maggi / Giovanna Bruni / Francesca Caso / Marcella Bini

    Nanomaterials, Vol 14, Iss 1, p

    2024  Volume 113

    Abstract: Poorly water-soluble drugs represent a challenge for the pharmaceutical industry because it is necessary to find properly tuned and efficient systems for their release. In this framework, organic–inorganic hybrid systems could represent a promising ... ...

    Abstract Poorly water-soluble drugs represent a challenge for the pharmaceutical industry because it is necessary to find properly tuned and efficient systems for their release. In this framework, organic–inorganic hybrid systems could represent a promising strategy. A largely diffused inorganic host is hydroxyapatite (HAP, Ca 10 (PO 4 ) 6 (OH) 2 ), which is easily synthesized with different external forms and can adsorb different kinds of molecules, thereby allowing rapid drug release. Hybrid nanocomposites of HAP nanorods, obtained through hydrothermal synthesis, were prepared with two model pharmaceutical molecules characterized by low and pH-dependent solubility: meloxicam, a non-steroidal anti-inflammatory drug, and bumetanide, a diuretic drug. Both hybrids were physically and chemically characterized through the combined use of X-ray powder diffraction, scanning electron microscopy with energy-dispersive spectroscopy, differential scanning calorimetry, and infrared spectroscopy measurements. Then, their dissolution profiles and hydrophilicity (contact angles) in different media as well as their solubility were determined and compared to the pure drugs. This hybrid system seems particularly suitable as a drug carrier for bumetanide, as it shows higher drug loading and good dissolution profiles, while is less suitable for meloxicam, an acid molecule.
    Keywords hydroxyapatite ; meloxicam ; bumetanide ; drug delivery ; inorganic–organic hybrids ; in vitro dissolution studies ; Chemistry ; QD1-999
    Subject code 500
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: No lockdown for neurological diseases during COVID19 pandemic infection.

    Caso, Valeria / Federico, Antonio

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2020  Volume 41, Issue 5, Page(s) 999–1001

    MeSH term(s) COVID-19 ; Humans ; Nervous System Diseases/epidemiology ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-08
    Publishing country Italy
    Document type Editorial
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-020-04389-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Carotid Interventions for Women: The Hazards and Benefits.

    Rockman, Caron / Caso, Valeria / Schneider, Peter A

    Stroke

    2022  Volume 53, Issue 2, Page(s) 611–623

    Abstract: The goal of the current review is to examine the hazards and benefits of carotid interventions in women and to provide recommendations for the indications for carotid intervention in female patients. Stroke and cerebrovascular disease are prevalent in ... ...

    Abstract The goal of the current review is to examine the hazards and benefits of carotid interventions in women and to provide recommendations for the indications for carotid intervention in female patients. Stroke and cerebrovascular disease are prevalent in women. There are inherent biological and other differences in men and women, which affect the manifestations and outcome of stroke, with women experiencing worse disability and higher mortality following ischemic stroke than men. Due to the underrepresentation of female patients in most clinical trials, the ability to make firm but alternative recommendations for women specifically on the management of carotid stenosis is challenging. Although some data suggest that women might have worse periprocedural outcomes as compared to men following all carotid revascularization procedures, there is also an abundance of data to support a similar risk for carotid procedures in men and women, especially with carotid endarterectomy and transcarotid artery revascularization. Therefore, the indications for carotid revascularization are the same in women as they are in men. The choice of a carotid revascularization procedure in women is based upon the same factors as in men and requires careful evaluation of a particular patient's risk profile, anatomic criteria, plaque morphology, and medical comorbidities that might favor one technique over the other. When performing carotid revascularization procedures in women, tailored techniques and procedures to address the small diameter of the female artery are warranted.
    MeSH term(s) Carotid Arteries/surgery ; Endarterectomy, Carotid/adverse effects ; Endarterectomy, Carotid/methods ; Endovascular Procedures ; Female ; Humans ; Male ; Neurosurgical Procedures/adverse effects ; Neurosurgical Procedures/methods ; Sex Characteristics ; Stents ; Treatment Outcome ; Women
    Language English
    Publishing date 2022-01-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.121.035386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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