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Article: Correspondence to: Management of Venous Thromboembolisms: Part II. The Consensus for Pulmonary Embolism and Updates.

Shao, Yu-Yun / Lin, Hung-Ju

2020 Volume 37, Issue 2, Page(s) 213–214

Language	English
Publishing date	2020-02-10
Publishing country	China (Republic : 1949- )
Document type	Journal Article
ZDB-ID	1051394-2
ISSN	1011-6842
ISSN	1011-6842
DOI	10.6515/ACS.202103_37(2).20210118B
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Article ; Online: Air versus Gas Tamponade for Primary Rhegmatogenous Retinal Detachment: A Systematic Review and Meta-Analysis.

Chen, Hung-Ju / Tsai, Yu-Lin / Hsiao, Chung-Hao / Chang, Chia-Jen

Ophthalmic research

2023 Volume 66, Issue 1, Page(s) 767–776

Abstract: Background: Air tamponade's effectiveness in treatment of rhegmatogenous retinal detachment (RRD) remains unclear.: Objective: We aimed to review the surgical outcomes between air and gas tamponade after vitrectomy for RRD.: Method: PubMed, ... ...

Abstract	Background: Air tamponade's effectiveness in treatment of rhegmatogenous retinal detachment (RRD) remains unclear. Objective: We aimed to review the surgical outcomes between air and gas tamponade after vitrectomy for RRD. Method: PubMed, Cochrane Library, EMBASE, and Web of Science were reviewed. The study protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO CRD42022342284). The primary outcome was the primary anatomical success after vitrectomy. The secondary outcome was the prevalence of postoperative ocular hypertension. Certainty of evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation system. Results: Ten studies involving 2,677 eyes were included. One study was randomized, and the others were non-randomized. The primary anatomical success after vitrectomy was not significantly different between the air and gas groups (odds ratio [OR], 1.00; 95% confidence interval [CI], 0.68-1.48). The risk of ocular hypertension was significantly lower in the air group (OR: 0.14; 95% CI: 0.09-0.24). The certainty of evidence regarding air tamponade having a comparable anatomical outcome and lower frequency of postoperative ocular hypertension in treatment of RRD were low. Discussion: The current evidence base for tamponade selection in treatment of RRD has several major limitations. Further appropriately designed studies are needed to guide tamponade selection.
MeSH term(s)	Humans ; Retinal Detachment/surgery ; Visual Acuity ; Eye ; Vitrectomy/methods ; Postoperative Complications/surgery ; Ocular Hypertension ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2023-03-27
Publishing country	Switzerland
Document type	Systematic Review ; Meta-Analysis
ZDB-ID	205708-6
ISSN	1423-0259 ; 0030-3747
ISSN (online)	1423-0259
ISSN	0030-3747
DOI	10.1159/000530232
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Article: Systolic blood pressure as a critical mediator in the association between adult height and 25-year risk of stroke.

Fan, Hsien-Yu / Hsu, Hsin-Yin / Lin, Hung-Ju / Chen, Yun-Yu / Chen, Yang-Ching / Su, Ta-Chen / Chien, Kuo-Liong

Obesity research & clinical practice

2024

Abstract: Background: Adult height is associated with the risk of stroke. However, the underlying mechanism remains unclear. We explored the mediating role of metabolic factors in the association between adult height and stroke incidence.: Methods: We used ... ...

Abstract	Background: Adult height is associated with the risk of stroke. However, the underlying mechanism remains unclear. We explored the mediating role of metabolic factors in the association between adult height and stroke incidence. Methods: We used data from 3306 community-dwelling participants with complete information on adult height, metabolic factors, and 25-year cardiovascular outcomes. Participants were classified into three adult height groups based on sex-specific height quartiles: short (Q1), average (Q2-Q3), and tall (Q4). The primary endpoint was the occurrence of cardiovascular disease, including coronary artery disease and stroke. Results: Taller adult height was associated with a lower risk of stroke. Compared with the short group the risk of stroke reduced with taller height with a hazard ratio (HR) of 0.68 in the average group (95% confidence interval [CI]: 0.50-0.93), and 0.45 in the tall group (95% CI: 0.31-0.65). Low systolic blood pressure was considered as a protective mediator in the effect of adult height on the risk of stroke in the average (HR: 0.86; 95% CI: 0.82-0.93) and the tall group (HR: 0.85; 95% CI: 0.78-0.91). Systolic blood pressure significantly contributed to height-related stroke risk (proportion mediated: 0.41; 95% CI: 0.19-1.56). Conclusions: This study found an inverse association between adult height and stroke risk, which is partly driven by lower systolic blood pressure. These findings highlight the importance of systolic blood pressure management as a potential preventive strategy against stroke.
Language	English
Publishing date	2024-04-02
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2274031-4
ISSN	1878-0318 ; 1871-403X
ISSN (online)	1878-0318
ISSN	1871-403X
DOI	10.1016/j.orcp.2024.03.002
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Article ; Online: Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008-2020.

Huang, Chung-I / Ker, Chien-Yu / Li, Hung-Ju / Hsiao, Yu-Ting / Lin, Sheng-Fung / Su, Yu-Chieh

International journal of hematology

2024

Abstract: The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent years. This epidemiological study using population-based registry data aimed to determine the incidence patterns of common subtypes of ... ...

Abstract	The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent years. This epidemiological study using population-based registry data aimed to determine the incidence patterns of common subtypes of TCL in Taiwan from 2008-2020 and compare them with those in the US and the Asian/Pacific Islander (API) population. Subtypes included angioimmunoblastic T-cell lymphoma (AITL); extranodal NK/T-cell lymphoma, nasal or other type (ENKTL); peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS); and anaplastic large cell lymphoma (ALCL). The total number of patients newly diagnosed with TCL during 2008-2020 was 4477, 3171, and 48,889 in Taiwan, API, and the US, respectively. Except the incidence rate of AITL in Taiwan, the incidence rates of these common TCL subtypes showed downward trends in all studied populations. There was also a significant increase in the relative frequency of AITL among TCL in Taiwan, with an annual percent change of 4.44 (p < 0.001), from 8.44% in 2002 to 20.63% in 2020. The rapid development of diagnostics may be the main factor contributing to this rise in incidence.
Language	English
Publishing date	2024-03-17
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1076875-0
ISSN	1865-3774 ; 0917-1258 ; 0925-5710
ISSN (online)	1865-3774
ISSN	0917-1258 ; 0925-5710
DOI	10.1007/s12185-024-03746-8
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Article ; Online: Increased mortality with intensive control in patients with higher baseline SBP and lower Framingham risk.

Pan, Heng-Yu / Lin, Hung-Ju / Chen, Wen-Jone / Wang, Tzung-Dau

Journal of hypertension

2022 Volume 40, Issue 5, Page(s) 978–984

Abstract: Objective: In the Systolic Blood Pressure Intervention Trial (SPRINT), the relative reduction in primary outcome with intensive blood pressure (BP) control was numerically smallest in the highest baseline SBP tertile. In this post hoc analysis of SPRINT, ...

Abstract	Objective: In the Systolic Blood Pressure Intervention Trial (SPRINT), the relative reduction in primary outcome with intensive blood pressure (BP) control was numerically smallest in the highest baseline SBP tertile. In this post hoc analysis of SPRINT, the goal was to explore whether the effects of intensive BP treatment varied among patients with different baseline SBP and cardiovascular risks. Methods: Patient-level data from 9361 randomized participants in SPRINT were used. Heterogeneity between treatment and patient characteristics were examined stratified by different baseline SBP levels. Cumulative incidences of primary outcome and all-cause death were compared between treatment groups for patients with baseline SBP at least 160 mmHg and lower Framingham risk. Results: For participants with a baseline SBP of at least 160 mmHg, intensive treatment was associated with a higher rate of all-cause death as compared with standard treatment (1.86 vs. 1.62% per year). After adjustment for age and sex, intensive treatment was associated with significantly increased all-cause death compared with standard treatment [hazard ratio (95% CI) for intensive group: 3.12 (1.00-9.69); P = 0.049] in participants with an SBP of at least 160 mmHg and a Framingham risk score of 31.3% or less (average of median and geometric mean). Patient outcomes were otherwise similar regarding age, use of antihypertensive therapy, cardiovascular disease or chronic kidney disease. Conclusion: Among the SPRINT participants with a baseline SBP of at least 160 mmHg and a lower Framingham risk score, targeting an SBP of less than 120mmHg compared with less than 140mmHg resulted in a significantly higher rate of all-cause death.
MeSH term(s)	Cardiovascular Diseases/prevention & control ; Female ; Heart Disease Risk Factors ; Humans ; Male ; Renal Insufficiency, Chronic ; Research Design ; Risk Factors
Language	English
Publishing date	2022-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	605532-1
ISSN	1473-5598 ; 0263-6352 ; 0952-1178
ISSN (online)	1473-5598
ISSN	0263-6352 ; 0952-1178
DOI	10.1097/HJH.0000000000003100
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Article ; Online: Higher risk of future events, mortality and greater healthcare use among patients with increasingly recurrent atherosclerotic cardiovascular disease events in Taiwan: a retrospective cohort study.

Hsu, Chia-Yun / Chen, Wen-Jone / Lin, Hung-Ju / Chen, Ho-Min / Yang, Yea-Harn / Chen, Wei-Ju / Chen, Chieh-Min / Hsiao, Fei-Yuan

BMJ open

2023 Volume 13, Issue 7, Page(s) e064219

Abstract: Objectives: To describe the occurrence of recurrent atherosclerotic cardiovascular disease (ASCVD) events within 3 years after a new-onset event, the associated disease burden and statin prescribing in patients with ASCVD in Taiwan.: Design: ... ...

Abstract	Objectives: To describe the occurrence of recurrent atherosclerotic cardiovascular disease (ASCVD) events within 3 years after a new-onset event, the associated disease burden and statin prescribing in patients with ASCVD in Taiwan. Design: Retrospective cohort study. Setting: This was a retrospective cohort study using Taiwan's National Health Insurance Research Database. Participants: In total, 111 399, 133 538 and 21 572 patients who were hospitalised with diagnosis of coronary heart disease (CHD), cerebrovascular disease (CBVD) and peripheral artery disease (PAD), respectively, between 1 January 2012 and 31 December 2014. Primary and secondary outcome measures: For each index and recurrent event, patients were observed for 12 months after admission to quantify risks of mortality, recurrent events, statin treatment and healthcare use. Results: We identified 97 321, 120 914 and 14 794 patients with new-onset CHD, CBVD and PAD, respectively. The proportions of developing first, second and third recurrent events were 22.5%, 25.6% and 30.9% for CHD; 20.9%, 26.2% and 32.4% for CBVD and 40.2%, 41.4% and 43.6% for PAD, respectively. Most patients had the same type of ASCVD for their recurrent events as their new-onset event. The mortality rates increased with each recurrent event (p<0.05 for all three ASCVD groups). The rates of hospital readmission and emergency room (ER) visit increased with increasing recurrent events. For example, in the CHD group, the 1-year readmission rates following the index, first and second recurrent events were 43.1%, 47.6% and 55.3%, respectively, and the proportions of visiting ER were 46.4%, 51.9% and 57.8%, respectively. Statin prescribing was suboptimal at time of index event and recurrent events. Conclusion: Recurrent ASCVD events were associated with a higher risk of recurrent event and mortality and greater healthcare use. However, statin prescriptions at index event and after each recurrent event were suboptimal.
MeSH term(s)	Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Cardiovascular Diseases/epidemiology ; Retrospective Studies ; Taiwan/epidemiology ; Atherosclerosis/epidemiology ; Delivery of Health Care ; Risk Factors
Chemical Substances	Hydroxymethylglutaryl-CoA Reductase Inhibitors
Language	English
Publishing date	2023-07-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-064219
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Article ; Online: Redox-Active High-Performance Polyimides as Versatile Electrode Materials for Organic Lithium- and Sodium-Ion Batteries.

Lubis, Andre Lammiduk / Baskoro, Febri / Lin, Ting-Hsuan / Wong, Hui Qi / Liou, Guey-Sheng / Yen, Hung-Ju

ACS applied materials & interfaces

2023

Abstract: Organic electrode materials for rechargeable batteries show great promise for improving the storage capacity, reducing production costs, and minimizing environmental impact toward sustainability. In this study, we report a series of newly synthesized ... ...

Abstract	Organic electrode materials for rechargeable batteries show great promise for improving the storage capacity, reducing production costs, and minimizing environmental impact toward sustainability. In this study, we report a series of newly synthesized arylamine-based polyimides, TPPA-PIs, with three different bridge functionalizations on the imide rings and isomeric constituents that can work as versatile battery electrodes. As a lithium-ion battery cathode, a maximum energy density of 248 Wh kg
Language	English
Publishing date	2023-12-26
Publishing country	United States
Document type	Journal Article ; Review
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c10722
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Article: Nocturnal Non-Dipping: An Overlooked Clinical Manifestation of Subclinical Hypothyroidism Linking to Increased Cardiovascular Risk.

Lin, Hung-Ju / Wang, Tzung-Dau

Acta Cardiologica Sinica

2017 Volume 33, Issue 5, Page(s) 495–497

Language	English
Publishing date	2017-08-31
Publishing country	China (Republic : 1949- )
Document type	Editorial
ZDB-ID	1051394-2
ISSN	1011-6842
ISSN	1011-6842
DOI	10.6515/acs20170626b
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Article: Profiling the Evolution of Inflammatory Response and Exploring Its Prognostic Significance in Acute Myocardial Infarction: The First Step to Establishing Anti-Inflammatory Strategy.

Lin, Hung-Ju / Wang, Tzung-Dau

Acta Cardiologica Sinica

2017 Volume 33, Issue 5, Page(s) 486–488

Language	English
Publishing date	2017-08-31
Publishing country	China (Republic : 1949- )
Document type	Editorial
ZDB-ID	1051394-2
ISSN	1011-6842
ISSN	1011-6842
DOI	10.6515/acs20170731a
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Article: Incidence Trend of Follicular Lymphoma in Taiwan Compared to Japan and Korea, 2001-2019.

Chiu, Liang-Chun / Lin, Chih-Wen / Li, Hung-Ju / Chen, Jian-Han / Chuang, Fu-Cheng / Lin, Sheng-Fung / Chang, Yu / Su, Yu-Chieh

Journal of clinical medicine

2023 Volume 12, Issue 4

Abstract: A continuous increase in follicular lymphoma has been observed in Taiwan, Japan, and South Korea over the last few decades. This study aimed to evaluate the difference in incidence trends of follicular lymphoma in Taiwan, Japan, and South Korea between ... ...

Abstract	A continuous increase in follicular lymphoma has been observed in Taiwan, Japan, and South Korea over the last few decades. This study aimed to evaluate the difference in incidence trends of follicular lymphoma in Taiwan, Japan, and South Korea between 2001 and 2019. The data for the Taiwanese populations was obtained from the Taiwan Cancer Registry Database, and those for the Japanese and Korean population were retrieved from the Japan National Cancer Registry and some additional reports, both of which included population-based cancer registry data, from Japan and Korea. Follicular lymphoma accounted for 4231 cases from 2002-2019 in Taiwan, 3744 cases from 2001-2008 and 49,731 cases from 2014-2019 in Japan; and 1365 cases from 2001-2012 and 1244 cases from 2011-2016 in South Korea. The annual percentage change for each time period was 3.49% (95% confidence interval: 2.75-4.24%) in Taiwan, 12.66% (95% confidence interval [CI]: 9.59-15.81%) and 4.95% (95% CI: 2.14-7.84%) in Japan, and 5.72% (95% CI: 2.79-8.73%) and 7.93% (95% CI: -1.63-18.42%) in South Korea. Our study confirms that the increasing trends of follicular lymphoma incidence in Taiwan and Japan have been remarkable in recent years, especially the rapid increase in Japan between 2014 and 2019; however, there was no significant in-crease from 2011 to 2015 in South Korea.
Language	English
Publishing date	2023-02-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12041417
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