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  1. Article ; Online: Nodular fasciitis on the zygomatic region: a rare presentation.

    Souza e Souza, Ilner de / Rochael, Mayra Carriijo / Farias, Rogério Estevam / Vieira, Roberto Bezerra / Vieira, Janaina Silva Tirapelle / Schimidt, Nathalia Campos

    Anais brasileiros de dermatologia

    2013  Volume 88, Issue 6 Suppl 1, Page(s) 89–92

    Abstract: Nodular fasciitis is a benign tumor, resulting from reactive proliferation composed of fibroblastic/myofibroblastic cells. Due to its rapid growth and high cellularity it may be mistaken for sarcoma. Despite the possibility of spontaneous regression, ... ...

    Abstract Nodular fasciitis is a benign tumor, resulting from reactive proliferation composed of fibroblastic/myofibroblastic cells. Due to its rapid growth and high cellularity it may be mistaken for sarcoma. Despite the possibility of spontaneous regression, excision is the treatment of choice. A 24-year-old female patient presented with a nodule on the zygomatic region with 3 months of evolution. Excisional biopsy was performed. Histopathological examination associated with immunohistochemical markers HHF35, AML and Ki-67 allowed diagnostic confirmation. The main relevance of the case presented is its rare location, suggesting its inclusion among the differential diagnoses of tumor lesions on the face.
    MeSH term(s) Biopsy ; Diagnosis, Differential ; Facial Dermatoses/pathology ; Fasciitis/pathology ; Female ; Humans ; Sarcoma/pathology ; Skin Neoplasms/pathology ; Young Adult ; Zygoma
    Language English
    Publishing date 2013-12-18
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/abd1806-4841.20132474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Síndrome de Goltz

    Ilner de Souza-e-Souza / Paula Cristina Assef dos Santos Cunha

    Anais Brasileiros de Dermatologia, Vol 78, Iss 1, Pp 91-

    relato de dois casos Goltz syndrome: report of two cases

    2003  Volume 97

    Abstract: A hipoplasia dérmica focal é genodermatose rara, de caráter dominante, ligada ao cromossoma X. Os ... autores apresentam dois casos dessa síndrome, destacando suas principais características dermatológicas e ... a importância da avaliação multidisciplinar em seu diagnóstico e acompanhamento. Focal dermal hypoplasia is ...

    Abstract A hipoplasia dérmica focal é genodermatose rara, de caráter dominante, ligada ao cromossoma X. Os autores apresentam dois casos dessa síndrome, destacando suas principais características dermatológicas e a importância da avaliação multidisciplinar em seu diagnóstico e acompanhamento. Focal dermal hypoplasia is a rare X-linked dominant genodermatosis. Two cases of Goltz-Gorlin syndrome are reported, showing the clinical manifestations, necessity of multidisciplinary evaluation, diagnosis and continuous follow-up.
    Keywords atrofia ; hipoplasia dérmica focal ; atrophy ; focal dermal hypoplasia ; Dermatology ; RL1-803 ; Medicine ; R ; DOAJ:Dermatology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2003-02-01T00:00:00Z
    Publisher Sociedade Brasileira de Dermatologia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Síndrome REM associada a lúpus eritematoso sistêmico e hipotireoidismo REM syndrome associated with systemic lupus erythematosus and hypotiroidism

    Eleonora Dantas Dias / Antônio Pedro Schetinne / Isabel Cristina Lima / Maria do Socorro A. de Souza / Ilner da Souza e Souza

    Anais Brasileiros de Dermatologia, Vol 80, Pp S376-S

    2005  Volume 379

    Abstract: A mucinose eritematosa reticulada é síndrome crônica e rara de etiologia desconhecida que afeta ... adultos jovens e de meia idade, principalmente do sexo feminino. Clinicamente é caracterizada por máculas ... eritematosas reticulares, pápulas e placas localizadas de forma simétrica em área central do tórax e dorso. Em ...

    Abstract A mucinose eritematosa reticulada é síndrome crônica e rara de etiologia desconhecida que afeta adultos jovens e de meia idade, principalmente do sexo feminino. Clinicamente é caracterizada por máculas eritematosas reticulares, pápulas e placas localizadas de forma simétrica em área central do tórax e dorso. Em aproximadamente 20% dos casos pode estar associada com várias doenças, especialmente auto-imunes. Os autores apresentam um caso de mucinose eritematosa reticulada associada a lúpus eritematoso sistêmico e hipotireoidismo. Reticular erythematous mucinosis is a chronic and rare syndrome of unknow aetiology that affects young adult and midle-aged women. Clinical presentation is characterized by macular and reticulated erythema, papula and plaques on the central chest and upper back of simmetrical form. In approximately 20% of the cases may be associated with a variety of disorders, especially auto-immune diseases. The authors present a case of reticular erythematous mucinoses associated with systemic lupus erythematosus and hypothiroidism.
    Keywords Hipotireoidismo ; Lupus eritematoso sistêmico ; Mucinoses ; Hypothyroidism ; Lupus erythematosus ; systemic ; Dermatology ; RL1-803 ; Medicine ; R ; DOAJ:Dermatology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2005-12-01T00:00:00Z
    Publisher Sociedade Brasileira de Dermatologia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Leishmania (Viannia) guyanensis induces low immunologic responsiveness in leishmaniasis patients from an endemic area of the Brazilian Amazon Highland.

    Matta, Nubia Estela / Nogueira, Ricardo S / Franco, Antonia Maria Ramos / de Souza E Souza, Ilner / Mattos, Marise S / Oliveira-Neto, Manoel P / Coutinho, Sergio G / Leon, Leonor L / Da-Cruz, Alda Maria

    The American journal of tropical medicine and hygiene

    2009  Volume 80, Issue 3, Page(s) 339–344

    Abstract: Cutaneous leishmaniasis caused by Leishmania (Viannia) guyanensis (CL-Lguy) is endemic in the Brazilian Amazon, differing from L. braziliensis infection in clinical, diagnostic, and therapeutic aspects. T-cell reactivity to leishmanial antigens possibly ... ...

    Abstract Cutaneous leishmaniasis caused by Leishmania (Viannia) guyanensis (CL-Lguy) is endemic in the Brazilian Amazon, differing from L. braziliensis infection in clinical, diagnostic, and therapeutic aspects. T-cell reactivity to leishmanial antigens possibly involved in the pathogenesis of CL-Lguy was studied herein. Variable lymphoproliferative responses (LPRs) to Leishmania antigens were found among the 23 studied patients, and 50% of them showed low or no response to these antigens. Active disease was associated with an enrichment of leishmanial-reactive T lymphocytes, mainly TCD4(+). High and low interferon (IFN)-gamma producers were observed. TNF-alpha, interleukin (IL)-10, and IL-5 were consistently detected. CL-Lguy displayed low antibody response in comparison to L. braziliensis patients. CL caused by L. braziliensis presented positive LPRs and higher IFN-gamma production but undetectable IL-5. L. guyanensis seems to induce a down-regulation of the immune system compared with L. braziliensis. This finding could explain some aspects of clinical presentation of CL-Lguy, such as high tissue parasite burden and frequent resistance to therapy.
    MeSH term(s) Adolescent ; Adult ; Animals ; Antibodies, Protozoan/biosynthesis ; Brazil/epidemiology ; Case-Control Studies ; Cytokines/biosynthesis ; Cytokines/blood ; Endemic Diseases ; Female ; Humans ; Leishmania guyanensis/immunology ; Leishmaniasis, Mucocutaneous/epidemiology ; Leishmaniasis, Mucocutaneous/immunology ; Leishmaniasis, Mucocutaneous/parasitology ; Lymphocyte Subsets/immunology ; Male ; Young Adult
    Chemical Substances Antibodies, Protozoan ; Cytokines
    Language English
    Publishing date 2009-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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