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  1. Article ; Online: Alternative splicing in EMT and TGF-β signaling during cancer progression.

    Zhang, Ying E / Stuelten, Christina H

    Seminars in cancer biology

    2024  Volume 101, Page(s) 1–11

    Abstract: Epithelial to mesenchymal transition (EMT) is a physiological process during development where epithelial cells transform to acquire mesenchymal characteristics, which allows them to migrate and colonize secondary tissues. Many cellular signaling ... ...

    Abstract Epithelial to mesenchymal transition (EMT) is a physiological process during development where epithelial cells transform to acquire mesenchymal characteristics, which allows them to migrate and colonize secondary tissues. Many cellular signaling pathways and master transcriptional factors exert a myriad of controls to fine tune this vital process to meet various developmental and physiological needs. Adding to the complexity of this network are post-transcriptional and post-translational regulations. Among them, alternative splicing has been shown to play important roles to drive EMT-associated phenotypic changes, including actin cytoskeleton remodeling, cell-cell junction changes, cell motility and invasiveness. In advanced cancers, transforming growth factor-β (TGF-β) is a major inducer of EMT and is associated with tumor cell metastasis, cancer stem cell self-renewal, and drug resistance. This review aims to provide an overview of recent discoveries regarding alternative splicing events and the involvement of splicing factors in the EMT and TGF-β signaling. It will emphasize the importance of various splicing factors involved in EMT and explore their regulatory mechanisms.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1033980-2
    ISSN 1096-3650 ; 1044-579X
    ISSN (online) 1096-3650
    ISSN 1044-579X
    DOI 10.1016/j.semcancer.2024.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2922: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Inhibitory effects of glutathione peroxidase on microbial spoilage of crayfish (

    Qin, Lerong / Li, Han / Zhang, Ying / Chen, Jiwang / Wang, Haibin / Liao, E

    Food chemistry: X

    2024  Volume 22, Page(s) 101388

    Abstract: The variety of enzyme-based biological preservatives is limited. This study evaluated the effects of glutathione peroxidase (GSH-Px) on the quality of crayfish during refrigerated storage by measuring the pH, total volatile basic nitrogen, trimethylamine, ...

    Abstract The variety of enzyme-based biological preservatives is limited. This study evaluated the effects of glutathione peroxidase (GSH-Px) on the quality of crayfish during refrigerated storage by measuring the pH, total volatile basic nitrogen, trimethylamine, and microbial contamination in crayfish muscle simulation system. The results revealed that 0.3% GSH-Px (CK3) not only suppressed the degradation of nitrogenous substances but also decreased the contamination levels of total viable, Enterobacteriaceae, and
    Language English
    Publishing date 2024-04-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2024.101388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of water washing and KOH activation for upgrading microalgal torrefied biochar.

    Zhang, Congyu / Fang, Jin / Chen, Wei-Hsin / Kwon, Eilhann E / Zhang, Ying

    The Science of the total environment

    2024  Volume 921, Page(s) 171254

    Abstract: Torrefaction is an effective pathway for microalgal solid biofuel upgrading, and alkali metal activation is also an efficient method to enhance fuel properties. This study explores the comparison of torrefaction alone and KOH activation combined with ... ...

    Abstract Torrefaction is an effective pathway for microalgal solid biofuel upgrading, and alkali metal activation is also an efficient method to enhance fuel properties. This study explores the comparison of torrefaction alone and KOH activation combined with torrefaction to determine a better operation for biochar production from the microalga Nannochloropsis Oceanica. The results indicate that the HHV ranges of KOH-activated biochar and unactivated biochar are 25.611-32.792 MJ·kg
    MeSH term(s) Microalgae ; Water/chemistry ; Biofuels ; Biomass ; Charcoal ; Temperature
    Chemical Substances biochar ; Water (059QF0KO0R) ; Biofuels ; Charcoal (16291-96-6)
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Loss of functional

    Iiams, Samantha E / Wan, Guijun / Zhang, Jiwei / Lugena, Aldrin B / Zhang, Ying / Hayden, Ashley N / Merlin, Christine

    iScience

    2024  Volume 27, Issue 2, Page(s) 108980

    Abstract: Light is one of the strongest cues for entrainment of circadian clocks. While some insect species rely only on visual input, others ... ...

    Abstract Light is one of the strongest cues for entrainment of circadian clocks. While some insect species rely only on visual input, others like
    Language English
    Publishing date 2024-01-20
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.108980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nature connectedness connects the visibility of trees through windows and mental wellbeing: a study on the "3 visible trees" component of the 3-30-300 rule.

    Li, Hansen / Browning, Matthew H E M / Bardhan, Mondira / Ying, Mingyue / Zhang, Xing / Cao, Yang / Zhang, Guodong

    International journal of environmental health research

    2024  , Page(s) 1–13

    Abstract: To examine the mediatory role of nature connectedness between tree visibility through windows and mental wellbeing, we conducted a questionnaire survey and examined the mediation effect using both cross-sectional and semi-longitudinal mediation models. ... ...

    Abstract To examine the mediatory role of nature connectedness between tree visibility through windows and mental wellbeing, we conducted a questionnaire survey and examined the mediation effect using both cross-sectional and semi-longitudinal mediation models. We evaluated nature connectedness using the Inclusion of Nature in Self (INS) scale and the Connectedness to Nature Scale (CNS) and measured mental wellbeing using the WHO-5 wellbeing index. Our results showed that participants who could see at least three trees through their windows reported higher levels of both nature connectedness and mental wellbeing compared to those without such visibility. Nature connectedness significantly mediated the relationship between the visibility of trees through windows and mental wellbeing, albeit with a somewhat limited effect. More broadly, this study provides additional evidence in support of the "3" component of the 3-30-300 "rule" for equitable access to greenspace in cities.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104887-6
    ISSN 1369-1619 ; 0960-3123
    ISSN (online) 1369-1619
    ISSN 0960-3123
    DOI 10.1080/09603123.2024.2334767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Characterizations and molecular docking mechanism of the interactions between peptide FDGDF (Phe-Asp-Gly-Asp-Phe) and SOD enzyme.

    Wen-Tao, C H E N / Zhang, Ying-Yang / Qiang, Qiang / Zou, Ping / Xu, Ying / Sun, Chengjun / Badar, Iftikhar Hussain

    Heliyon

    2024  Volume 10, Issue 2, Page(s) e24515

    Abstract: In this study, we investigated the antioxidant properties of dry-cured beef crude peptide (BPH) at different storage periods. The combination characteristics of different concentrations of Phe-Asp-Gly-Asp-Phe (FDGDF) and superoxide dismutase (SOD) at ... ...

    Abstract In this study, we investigated the antioxidant properties of dry-cured beef crude peptide (BPH) at different storage periods. The combination characteristics of different concentrations of Phe-Asp-Gly-Asp-Phe (FDGDF) and superoxide dismutase (SOD) at different temperatures were analyzed by ultraviolet-visible spectroscopy, fluorescence spectroscopy, and FT-IR spectroscopy, combined with the detection of a SOD activity detection box. It was found that FDGDF could improve the activity of SOD by changing its secondary structure. Bonds were formed at O32/O40/O52 using quantum chemical simulation calculations, and the Fukui index was higher than that of most atoms, indicating that these atoms were more likely to participate in the reaction. SPR biological force analysis showed that FDGDF and SOD were in a fast binding and dissociation mode. This study revealed the theoretical basis for studying the antioxidant mechanism of dry-cured beef and provided ideas for developing new dry-cured beef products.
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24515
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  7. Article ; Online: Abnormal expression of long non‑coding RNA LINC01270 in glioma and its correlation with X‑ray computed tomography signs.

    Liu, Ying / Zhang, Yuntao / E, Yongjun / Zhang, Xianglin / Ma, Heji / Dong, Furen

    Acta neurobiologiae experimentalis

    2024  Volume 84, Issue 1, Page(s) 43–50

    Abstract: This study focused on the association of LINC01270 and computed tomography (CT) signs with glioma development, to evaluate their potential in the early detection of glioma. Serum LINC01270 was evaluated in glioma patients and healthy individuals using ... ...

    Abstract This study focused on the association of LINC01270 and computed tomography (CT) signs with glioma development, to evaluate their potential in the early detection of glioma. Serum LINC01270 was evaluated in glioma patients and healthy individuals using PCR. The involvement of LINC01270 in glioma onset and development was evaluated by ROC and chi‑square test. The association of LINC01270 with the CT signs and their combined effects in the diagnosis in glioma were also estimated. Serum LINC01270 was significantly elevated in glioma patients, which was closely associated with patients' advanced WHO grades and lower KPS. Both LINC01270 upregulation and CT findings showed significant potential in diagnosing glioma, and LINC01270 correlated significantly with the invasion risk and metastasis indicated on CT. The combination of LINC01270 expression and CT findings significantly improved the sensitivity and specificity of glioma diagnosis. Upregulated LINC01270 in glioma is associated with malignant and severe disease development and has significant diagnostic value. Combined detection of LINC01270 and CT findings could improve the diagnostic efficacy in glioma cases, thus optimizing clinical diagnosis.
    MeSH term(s) Humans ; RNA, Long Noncoding/genetics ; Glioma/diagnostic imaging ; Glioma/genetics ; Tomography, X-Ray Computed ; Up-Regulation
    Chemical Substances RNA, Long Noncoding
    Language English
    Publishing date 2024-03-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 184409-x
    ISSN 1689-0035 ; 0065-1400
    ISSN (online) 1689-0035
    ISSN 0065-1400
    DOI 10.55782/ane-2024-2521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 479: Show issues Location:
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  8. Article: [Driving Forces and Mitigation Potential of CO

    Weng, Shu-Juan / Liu, Ying-Ying / Tang, Feng / Sha, Qing-E / Peng, Bo / Wang, Ye-Jia / Chen, Cheng / Zhang, Xue-Chi / Li, Jing-Jie / Chen, Hao-Qi / Zheng, Jun-Yu / Song, Xian-Zhong

    Huan jing ke xue= Huanjing kexue

    2024  Volume 45, Issue 1, Page(s) 115–122

    Abstract: Ships are important sources of carbon dioxide ( ... ...

    Abstract Ships are important sources of carbon dioxide (CO
    Language Chinese
    Publishing date 2024-01-12
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202301087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Characterizations and molecular docking mechanism of the interactions between peptide FDGDF (Phe-Asp-Gly-Asp-Phe) and SOD enzyme

    C.H.E.N. Wen-Tao / Ying-Yang Zhang / Qiang Qiang / Ping Zou / Ying Xu / Chengjun Sun / Iftikhar Hussain Badar

    Heliyon, Vol 10, Iss 2, Pp e24515- (2024)

    2024  

    Abstract: In this study, we investigated the antioxidant properties of dry-cured beef crude peptide (BPH) at different storage periods. The combination characteristics of different concentrations of Phe-Asp-Gly-Asp-Phe (FDGDF) and superoxide dismutase (SOD) at ... ...

    Abstract In this study, we investigated the antioxidant properties of dry-cured beef crude peptide (BPH) at different storage periods. The combination characteristics of different concentrations of Phe-Asp-Gly-Asp-Phe (FDGDF) and superoxide dismutase (SOD) at different temperatures were analyzed by ultraviolet–visible spectroscopy, fluorescence spectroscopy, and FT-IR spectroscopy, combined with the detection of a SOD activity detection box. It was found that FDGDF could improve the activity of SOD by changing its secondary structure. Bonds were formed at O32/O40/O52 using quantum chemical simulation calculations, and the Fukui index was higher than that of most atoms, indicating that these atoms were more likely to participate in the reaction. SPR biological force analysis showed that FDGDF and SOD were in a fast binding and dissociation mode. This study revealed the theoretical basis for studying the antioxidant mechanism of dry-cured beef and provided ideas for developing new dry-cured beef products.
    Keywords Beef crude proteins ; Binding sites ; Molecular docking ; SPR ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 540
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Cryoprotective Effects of Carrageenan Oligosaccharides on Crayfish (

    Liao, E / Wu, Yuxin / Pan, Yang / Zhang, Ying / Zhang, Peng / Chen, Jiwang

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 11

    Abstract: Cryoprotectants are widely used to protect muscle tissue from ice crystal damage during the aquatic products freezing process, but traditional phosphate cryoprotectants may cause an imbalance in the calcium-to-phosphorus ratio for the human body. This ... ...

    Abstract Cryoprotectants are widely used to protect muscle tissue from ice crystal damage during the aquatic products freezing process, but traditional phosphate cryoprotectants may cause an imbalance in the calcium-to-phosphorus ratio for the human body. This study evaluated the effects of carrageenan oligosaccharides (CRGO) on quality deterioration and protein hydrolysis of crayfish (
    Language English
    Publishing date 2023-06-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12112258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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