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Article ; Online: Efficient 3D Low-Discrepancy k -Space Sampling Using Highly Adaptable Seiffert Spirals.

Speidel, T / Metze, P / Rasche, V

2018 Volume 38, Issue 8, Page(s) 1833–1840

Abstract: ... by enhancing the efficiency of k -space sampling. This can be achieved by increasing the coverage of k -space ... properties. In this paper, a versatile 3D center-out k -space trajectory based on Jacobian elliptic functions ... Seiffert's spiral) is presented. The trajectory leads to a low-discrepancy coverage of k -space using ...

Abstract	The overall duration of acquiring a Nyquist sampled 3D dataset can be significantly shortened by enhancing the efficiency of k -space sampling. This can be achieved by increasing the coverage of k -space for every trajectory interleave. Furthermore, acceleration is possible by making use of advantageous undersampling properties. In this paper, a versatile 3D center-out k -space trajectory based on Jacobian elliptic functions (Seiffert's spiral) is presented. The trajectory leads to a low-discrepancy coverage of k -space using a considerably reduced number of readouts compared with other approaches. Such a coverage is achieved for any number of interleaves, and, therefore, even single-shot trajectories can be constructed to be combined with, for example, hyperpolarized media. Furthermore, acceleration is achievable due to non-coherent undersampling properties of the trajectory in combination with non-linear reconstruction techniques like compressed sensing (CS). Simulations of point-spread functions and discrepancy evaluations compare Seiffert's spiral to the established 3D cones approach. Imaging capabilities are evaluated by comparison of in vivo knee images using Nyquist and undersampled datasets in combination with CS reconstructions.
MeSH term(s)	Algorithms ; Databases, Factual ; Humans ; Imaging, Three-Dimensional/methods ; Knee/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Phantoms, Imaging ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2018-12-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	622531-7
ISSN	1558-254X ; 0278-0062
ISSN (online)	1558-254X
ISSN	0278-0062
DOI	10.1109/TMI.2018.2888695
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Article ; Online: Quasi-Random Single-Point Imaging Using Low-Discrepancy $k$ -Space Sampling.

Speidel, Tobias / Paul, Jan / Wundrak, Stefan / Rasche, Volker

IEEE transactions on medical imaging

2017 Volume 37, Issue 2, Page(s) 473–479

Abstract: Magnetic resonance imaging of short relaxation time spin systems has been a widely discussed topic with serious clinical applications and led to the emergence of fast imaging ultra-short echo-time sequences. Nevertheless, these sequences suffer from ... ...

Abstract	Magnetic resonance imaging of short relaxation time spin systems has been a widely discussed topic with serious clinical applications and led to the emergence of fast imaging ultra-short echo-time sequences. Nevertheless, these sequences suffer from image blurring, due to the related sampling point spread function and are highly prone to imaging artefacts arising from, e.g., chemical shifts or magnetic susceptibilities. In this paper, we present a concept of spherical quasi-random single-point imaging. The approach is highly accelerateable, due to intrinsic undersampling properties and capable of strong metal artefact suppression. Imaging acceleration is achieved by sampling of quasi-random points in -space, based on a low-discrepancy sequence, and a combination with non-linear optimization reconstruction techniques [compressed sensing (CS)]. The presented low-discrepancy trajectory shows ideal noise like undersampling properties for the combination with CS, leading to denoised images with excellent metal artefact reduction. Using eightfold undersampling, acquisition time of a few minutes can be achieved for volume acquisitions.
MeSH term(s)	Algorithms ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Phantoms, Imaging
Language	English
Publishing date	2017-10-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	622531-7
ISSN	1558-254X ; 0278-0062
ISSN (online)	1558-254X
ISSN	0278-0062
DOI	10.1109/TMI.2017.2760919
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Book: Willkommen im Hebammensalon

Dannhauer, Kareen / Rasche, Sissi

der charmanteste Ort für alle Fragen rund um Schwangerschaft und Geburt

2022

Author's details	Kareen Dannhauer, Sissi Rasche
Language	German
Size	269 Seiten, 21.6 cm x 13.7 cm, 376 g
Publisher	Kösel
Publishing place	München
Publishing country	Germany
Document type	Book
HBZ-ID	HT021574960
ISBN	978-3-466-31180-4 ; 3-466-31180-2 ; 9783641286002 ; 364128600X
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Article: K-strategic ammonia-oxidizing bacteria capitalize on biological nitrogen fixation in a flooded, unfertilized rice soil

Bei, Qicheng / Xie, Zubin / Cadisch, Georg / Rasche, Frank

Biology and fertility of soils. 2019 Oct., v. 55, no. 7

2019

Abstract: ... gradient fractions were closely related to K-strategic Nitrosospira cluster 10, including Nitrosospira sp ... suggested that K-strategy is the underlying ecological mechanism of sustainable, self-regulating ... if some rice-associated diazotrophs might also be classified as K-strategists, since BNF is an energy demanding ...

Abstract	Less attention has been devoted to the understanding of the sequential effect of biological nitrogen fixation (BNF) on microbial ammonia (NH3) oxidation in terrestrial soils. To shed light into this ecologically important relationship, a 15N2-DNA-stable isotope probing (SIP) technique was applied to explore the incorporation of 15N fixed by BNF into the genome of NH3 oxidizers in planted and non-planted flooded rice soils, using the α-subunit of NH3 monooxygenase (amoA gene) as a functional marker. The abundance and structural composition of archaeal and bacterial amoA genes in density-resolved fractions obtained from SIP were investigated by quantitative PCR, as well as terminal-restriction fragment length polymorphism and sequence analyses. Results revealed that bacterial rather than archaeal NH3 oxidizers assimilated 15N derived from BNF in both planted and non-planted flooded rice soils. The amoA genes in 15N-enriched “heavy” SIP gradient fractions were closely related to K-strategic Nitrosospira cluster 10, including Nitrosospira sp. AF-like bacteria, suggesting an ecological linkage of these two metabolically distinct processes. It remains unsolved from our study why exactly Nitrosospira cluster 10 was capitalizing on BNF. It could be suggested that K-strategy is the underlying ecological mechanism of sustainable, self-regulating terrestrial ecosystems such as traditional, unfertilized flooded rice soils. In this regard, it needs to be assayed if some rice-associated diazotrophs might also be classified as K-strategists, since BNF is an energy demanding metabolic process.
Keywords	Archaea ; Nitrosospira ; ammonia ; energy ; enzymes ; genes ; isotope labeling ; nitrifying bacteria ; nitrogen ; nitrogen fixation ; nitrogen-fixing bacteria ; oxidants ; oxidation ; quantitative polymerase chain reaction ; rice soils ; sequence analysis ; stable isotopes ; terrestrial ecosystems
Language	English
Dates of publication	2019-10
Size	p. 713-722.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	742137-0
ISSN	1432-0789 ; 0178-2762
ISSN (online)	1432-0789
ISSN	0178-2762
DOI	10.1007/s00374-019-01387-2
Database	NAL-Catalogue (AGRICOLA)

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Article: Complete Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Myophage Miro.

Mijalis, Eleni M / Lessor, Lauren E / Cahill, Jesse L / Rasche, Eric S / Kuty Everett, Gabriel F

Genome announcements

2015 Volume 3, Issue 5

Abstract: ... nosocomial infections. Bacteriophage therapy against K. pneumoniae may be possible to combat these infections ... The following describes the complete genome sequence and key features of the pseudo-T-even K. pneumoniae ... carbapenemase (KPC)-producing K. pneumoniae myophage Miro. ...

Abstract	Klebsiella pneumoniae is a Gram-negative pathogen frequently associated with antibiotic-resistant nosocomial infections. Bacteriophage therapy against K. pneumoniae may be possible to combat these infections. The following describes the complete genome sequence and key features of the pseudo-T-even K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae myophage Miro.
Language	English
Publishing date	2015-10-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2704277-7
ISSN	2169-8287
ISSN	2169-8287
DOI	10.1128/genomeA.01137-15
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Article: Complete Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Siphophage Sushi.

Nguyen, Dat T / Lessor, Lauren E / Cahill, Jesse L / Rasche, Eric S / Kuty Everett, Gabriel F

Genome announcements

2015 Volume 3, Issue 5

Abstract: ... The following reports the complete genome sequence of K. pneumoniae carbapenemase-producing K. pneumoniae T1 ...

Abstract	Klebsiella pneumoniae is a Gram-negative bacterium in the family Enterobacteriaceae. It is associated with numerous nosocomial infections, including respiratory and urinary tract infections in humans. The following reports the complete genome sequence of K. pneumoniae carbapenemase-producing K. pneumoniae T1-like siphophage Sushi and describes its major features.
Language	English
Publishing date	2015-09-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2704277-7
ISSN	2169-8287
ISSN	2169-8287
DOI	10.1128/genomeA.00994-15
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Article ; Online: Acceleration of tissue phase mapping by k-t BLAST: a detailed analysis of the influence of k-t-BLAST for the quantification of myocardial motion at 3T.

Lutz, Anja / Bornstedt, Axel / Manzke, Robert / Etyngier, Patrick / Nienhaus, G Ulrich / Rasche, Volker

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

2011 Volume 13, Page(s) 5

Abstract: ... For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging ... of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment ... of cardiac motion.: Results: It is demonstrated that a k-t BLAST factor of two can be used with a marginal ...

Abstract	Background: The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial and temporal resolution is limited by long data acquisition times. Therefore, a significant increase in imaging speed without deterioration of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment of cardiac motion. Results: It is demonstrated that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration of the quantitative motion data. Further increasing the k-t acceleration causes substantial alteration of the peak velocities and the motion pattern, but the temporal behavior of the contraction is well maintained up to an acceleration factor of six. Conclusions: The application of k-t BLAST for the acceleration of TPM appears feasible. A reduction of the acquisition time of almost 45% could be achieved without substantial loss of quantitative motion information.
MeSH term(s)	Adolescent ; Adult ; Female ; Germany ; Heart/anatomy & histology ; Heart/physiology ; Humans ; Image Interpretation, Computer-Assisted ; Magnetic Resonance Imaging, Cine ; Male ; Myocardial Contraction ; Time Factors ; Young Adult
Language	English
Publishing date	2011-01-11
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1458034-2
ISSN	1532-429X ; 1097-6647
ISSN (online)	1532-429X
ISSN	1097-6647
DOI	10.1186/1532-429X-13-5
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Article ; Online: High-resolution respiratory self-gated golden angle cardiac MRI: Comparison of self-gating methods in combination with k-t SPARSE SENSE.

Paul, Jan / Divkovic, Evica / Wundrak, Stefan / Bernhardt, Peter / Rottbauer, Wolfgang / Neumann, Heiko / Rasche, Volker

Magnetic resonance in medicine

2015 Volume 73, Issue 1, Page(s) 292–298

Abstract: ... in cardiac MRI in combination with iteratively reconstructed (k-t SPARSE SENSE) cine data with low and high ... from the respiratory bellows signal on average. Combination with k-t SPARSE SENSE enabled high temporally resolved ...

Abstract	Purpose: To compare the applicability of different self-gating (SG) strategies for respiratory SG in cardiac MRI in combination with iteratively reconstructed (k-t SPARSE SENSE) cine data with low and high temporal resolution. Methods: Eleven SG variants were compared in five volunteers by assessment of the resulting image sharpness compared with nongated reconstructions. Promising SG techniques were applied for high temporal resolution reconstructions of the heart function. Results: SG was successful in all volunteers with image-based SG and the ∑\|\|p\|\| technique. These approaches were also superior to gating from the respiratory bellows signal on average. Combination with k-t SPARSE SENSE enabled high temporally resolved visualization of the heart motion with free breathing. Conclusion: Respiratory SG can be applied for improving image sharpness. Combining SG with iterative reconstruction allows generation of high temporal resolution cine data, which reveal more details of cardiac motion.
MeSH term(s)	Adult ; Algorithms ; Female ; Heart/anatomy & histology ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods ; Magnetic Resonance Imaging, Cine/methods ; Male ; Pattern Recognition, Automated/methods ; Reproducibility of Results ; Respiratory-Gated Imaging Techniques/methods ; Sensitivity and Specificity ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2015-01
Publishing country	United States
Document type	Comparative Study ; Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605774-3
ISSN	1522-2594 ; 0740-3194
ISSN (online)	1522-2594
ISSN	0740-3194
DOI	10.1002/mrm.25102
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Article ; Online: Acceleration of tissue phase mapping by k-t BLAST

Nienhaus G Ulrich / Etyngier Patrick / Manzke Robert / Bornstedt Axel / Lutz Anja / Rasche Volker

Journal of Cardiovascular Magnetic Resonance, Vol 13, Iss 1, p

a detailed analysis of the influence of k-t-BLAST for the quantification of myocardial motion at 3T

2011 Volume 5

Abstract: ... of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was ... combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated ... that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration ...

Abstract	Abstract Background The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial and temporal resolution is limited by long data acquisition times. Therefore, a significant increase in imaging speed without deterioration of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment of cardiac motion. Results It is demonstrated that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration of the quantitative motion data. Further increasing the k-t acceleration causes substantial alteration of the peak velocities and the motion pattern, but the temporal behavior of the contraction is well maintained up to an acceleration factor of six. Conclusions The application of k-t BLAST for the acceleration of TPM appears feasible. A reduction of the acquisition time of almost 45% could be achieved without substantial loss of quantitative motion information.
Keywords	Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multienergy photon-counting K-edge imaging: potential for improved luminal depiction in vascular imaging.

Feuerlein, Sebastian / Roessl, Ewald / Proksa, Roland / Martens, Gerhard / Klass, Oliver / Jeltsch, Martin / Rasche, Volker / Brambs, Hans-Juergen / Hoffmann, Martin H K / Schlomka, Jens-Peter

Radiology

2008 Volume 249, Issue 3, Page(s) 1010–1016

Abstract: ... contrast agent, calcified plaque, and stent material by using the characteristic k edge of gadolinium ...

Abstract	The purpose of this study was to investigate whether spectral computed tomography (CT) has the potential to improve luminal depiction by differentiating among intravascular gadolinium-based contrast agent, calcified plaque, and stent material by using the characteristic k edge of gadolinium. A preclinical spectral CT scanner with a photon-counting detector and six energy threshold levels was used to scan a phantom vessel. A partially occluded stent was simulated by using a calcified plaque isoattenuated to a surrounding gadolinium chelate solution. The reconstructed images showed an effective isolation of the gadolinium with subsequent clear depiction of the perfused vessel lumen. The calcified plaque and the stent material are suppressed.
MeSH term(s)	Coronary Angiography/methods ; Gadolinium ; Phantoms, Imaging ; Photons ; Stents ; Tomography, X-Ray Computed/instrumentation ; Tomography, X-Ray Computed/methods
Chemical Substances	Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2008-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.2492080560
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