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  1. Article: Irene as teacher. Lessons learned combating East Coast hurricane apply elsewhere.

    Perlman, Lee / Waltman, Susan

    Modern healthcare

    2011  Volume 41, Issue 38, Page(s) 18

    MeSH term(s) Cyclonic Storms ; Disaster Planning ; Humans ; Mid-Atlantic Region ; Relief Work ; Southeastern United States
    Language English
    Publishing date 2011-09-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187602-8
    ISSN 0160-7480
    ISSN 0160-7480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unrecognized comorbid autism spectrum disorder in children initially diagnosed with only attention deficit hyperactivity disorder.

    Lee, Jeewon / Lee, Soyoung Irene

    Asian journal of psychiatry

    2023  Volume 85, Page(s) 103629

    Abstract: The present study examined the prevalence of autism spectrum disorder (ASD) in intellectually capable children with attention deficit hyperactivity disorder (ADHD). Retrospective chart review on 103 children (mean age= 7.83 ± 1.72 years female=15.53%), ... ...

    Abstract The present study examined the prevalence of autism spectrum disorder (ASD) in intellectually capable children with attention deficit hyperactivity disorder (ADHD). Retrospective chart review on 103 children (mean age= 7.83 ± 1.72 years female=15.53%), without intellectual disability, who were diagnosed with only ADHD were done. Among the 103 children 27 children (26.21%) were later co-diagnosed with ASD. The results of the present study provide helpful insights in accurate recognition of co-occurring ASD in intellectually capable children diagnosed with ADHD. The potential for the coexistence of ASD should always be given careful consideration when examining children with ADHD.
    MeSH term(s) Humans ; Child ; Female ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/epidemiology ; Autism Spectrum Disorder/complications ; Attention Deficit Disorder with Hyperactivity/diagnosis ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Retrospective Studies ; Intellectual Disability ; Prevalence
    Language English
    Publishing date 2023-05-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2023.103629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Real-Time Online Demonstration for Skills Education for First-Year Nursing Students.

    Wong, Irene Y F / Lee, Amy K S

    The Journal of nursing education

    2024  Volume 63, Issue 1, Page(s) 43–47

    Abstract: Background: Few studies have investigated first-year nursing students' perspectives after they received real-time online demonstration (RTOD) for fundamental nursing skills education.: Method: A mixed-methods study was conducted with prospective ... ...

    Abstract Background: Few studies have investigated first-year nursing students' perspectives after they received real-time online demonstration (RTOD) for fundamental nursing skills education.
    Method: A mixed-methods study was conducted with prospective second-year nursing students after they completed a one-semester RTOD class in their first year. With permission from the original authors, an online questionnaire, the Self-Structured Questionnaire (SSQ), was administered to 277 students in undergraduate and higher-diploma programs, followed by two focus group interviews with 13 students. Survey and focus group data were analyzed using descriptive statistics and thematic analysis, respectively.
    Results: Regarding students' barriers in administrative, individual, and technological areas, three themes emerged from the focus groups: (1) learning quality; (2) connection; and (3) impediments.
    Conclusion: RTOD contributed to fundamental nursing skills education. However, there was room for improvement.
    MeSH term(s) Humans ; Prospective Studies ; Students, Nursing ; Educational Status ; Learning ; Focus Groups
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410686-6
    ISSN 1938-2421 ; 0148-4834
    ISSN (online) 1938-2421
    ISSN 0148-4834
    DOI 10.3928/01484834-20231112-08
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Experiences of Motivational Interviewing in Virtual Health-care Visits for Adults With Type 2 Diabetes Mellitus: A Qualitative Analysis.

    Lau, Kimberley / Escudero, Carlos / Lee, Irene / Yu, Catherine

    Canadian journal of diabetes

    2024  

    Abstract: Objectives: The purpose of this qualitative study is to identify barriers minimizing the effectiveness of motivational interviewing during virtual clinic encounters for individuals with type 2 diabetes based on the capability, opportunity, motivation, ... ...

    Abstract Objectives: The purpose of this qualitative study is to identify barriers minimizing the effectiveness of motivational interviewing during virtual clinic encounters for individuals with type 2 diabetes based on the capability, opportunity, motivation, and behaviour (COM-B) model.
    Methods: One-on-one semistructured interviews were conducted from March to June 2023, with 17 adults with type 2 diabetes (64.7% female; median age 69 years, range 47 to 83 years) followed at St. Michael's Hospital (Toronto, Canada). Themes from transcribed interviews were identified through descriptive analysis using a grounded theory approach.
    Results: The following main themes were identified: 1) face-to-face appointments strengthen provider-patient rapport and collaboration; 2) virtual encounters reduce patient accountability and hinder health-seeking behaviour; and 3) individuals with physical disabilities and/or low technological proficiency experience decreased provider accessibility. Protective factors that can mitigate these negative impacts include establishing rapport during in-person appointments before transitioning to virtual appointments and incorporating a video component during virtual encounters.
    Conclusions: Several barriers of virtual appointments currently limit the effectiveness of motivational interviewing for individuals with type 2 diabetes and make it difficult to provide person-centred care, especially by phone. However, there are protective factors that help to maintain healthy lifestyle behaviours, even after transitioning to virtual settings, and are areas for optimization moving forward.
    Language English
    Publishing date 2024-04-18
    Publishing country Canada
    Document type Journal Article
    ISSN 2352-3840
    ISSN (online) 2352-3840
    DOI 10.1016/j.jcjd.2024.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cofilin activation in pancreatic acinar cells plays a pivotal convergent role for mediating CCK-stimulated enzyme secretion and growth.

    Ramos-Alvarez, Irene / Lee, Lingaku / Jensen, Robert T

    Frontiers in physiology

    2023  Volume 14, Page(s) 1147572

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1147572
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  6. Article ; Online: Successfully Managing Severe Anemia in a Trauma Patient Who Refused Blood Transfusion: A Case Report.

    Sanchez, Irene F / Lee, Han-Young / Lee, Jae-Myeong

    The American journal of case reports

    2023  Volume 24, Page(s) e940326

    Abstract: BACKGROUND Surgical management in patients who undergo traumatic blood loss but who refuse blood transfusion can be challenging, but physicians and surgeons must comply with the wishes and beliefs of their patients. This report describes the management ... ...

    Abstract BACKGROUND Surgical management in patients who undergo traumatic blood loss but who refuse blood transfusion can be challenging, but physicians and surgeons must comply with the wishes and beliefs of their patients. This report describes the management of severe anemia, with hemoglobin level of 2.5 g/dL, in a 71-year-old male Korean trauma patient who declined blood transfusion. CASE REPORT A 71-year-old man was admitted to hospital with severe blood loss following trauma. He declined blood transfusion due to his religious belief as a Jehovah's Witness. On day 4, the patient's hemoglobin level dropped from 7.7 to 3.9 g/dL. Despite the need for blood transfusion, the patient refused. Hence, therapeutic strategies, including crystalloid fluid resuscitation, bleeding control, vasopressor support, erythropoietin administration, supplementation with iron, folic acid, and vitamin B12, coagulopathy correction, oxygen consumption reduction, and mechanical ventilation were implemented. Following 16 days of supportive management, the hemoglobin reached 7.4 g/dL. However, it suddenly decreased on day 41 (2.5 g/dL) due to episodes of melena secondary to an actively bleeding gastric ulcer, which was successfully managed with endoscopic hemostasis. Despite increased vasopressor dosage and addition of vasopressin and hydrocortisone, the patient became unresponsive with persistent hypotension. Methylene blue was used as the final therapeutic agent. The patient responded well and subsequently recovered without blood transfusion. CONCLUSIONS This report has presented the clinical challenges of managing the case of a patient who requires but declines blood transfusion and has highlighted the approach to clinical care while respecting the wishes of the patient.
    MeSH term(s) Male ; Humans ; Aged ; Anemia/etiology ; Anemia/therapy ; Blood Transfusion ; Hemoglobins/analysis ; Jehovah's Witnesses ; Vitamin B 12/therapeutic use
    Chemical Substances Hemoglobins ; Vitamin B 12 (P6YC3EG204)
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.940326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prevalence of Attention Deficit Hyperactivity Disorder in Girls With Central Precocious Puberty.

    Lee, Jeewon / Lee, Soyoung Irene / Lee, Yoo Min / Hong, Yong Hee

    Journal of attention disorders

    2023  Volume 27, Issue 13, Page(s) 1460–1466

    Abstract: Objective: The purpose of the current study was to examine the prevalence of attention deficit hyperactivity disorder (ADHD) in girls with central precocious puberty.: Method: Girls with central precocious puberty were prospectively recruited from ... ...

    Abstract Objective: The purpose of the current study was to examine the prevalence of attention deficit hyperactivity disorder (ADHD) in girls with central precocious puberty.
    Method: Girls with central precocious puberty were prospectively recruited from the pediatric clinic. Screening was done with ADHD Rating Scale (ADHD-RS) and Child Behavior Checklist (CBCL). Those who screened positive on ADHD-RS were referred for the diagnostic evaluation which included a Computerized Performance Test (CPT) and a clinical interview conducted by a child adolescent psychiatrist.
    Results: Among the 81 girls (mean age = 8.97 ± 0.91) who completed the study, 11 girls (13.58%) were diagnosed with ADHD: 5 of them were inattentive type and 6 of them were combined type.
    Conclusion: The present exploratory study showed that the prevalence of ADHD in girls with central precocious was higher than the known worldwide prevalence of ADHD in children.
    MeSH term(s) Child ; Female ; Adolescent ; Humans ; Attention Deficit Disorder with Hyperactivity/diagnosis ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Prevalence ; Puberty, Precocious/diagnosis ; Puberty, Precocious/epidemiology ; Cognition
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2004350-8
    ISSN 1557-1246 ; 1087-0547
    ISSN (online) 1557-1246
    ISSN 1087-0547
    DOI 10.1177/10870547231180116
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  8. Article ; Online: Nontraumatic orbital hematoma secondary to labor and childbirth: a case report and review of the literature.

    Sheth, Nishita T / Lee, Irene T / Woodward, Julie A / Dermarkarian, Christopher R

    International ophthalmology

    2024  Volume 44, Issue 1, Page(s) 202

    Abstract: Purpose: Non-traumatic orbital hemorrhage without underlying vascular malformations or predisposing conditions is uncommon, and particularly rare in the context of maternal labor. This study combines a novel case report and retrospective review to ... ...

    Abstract Purpose: Non-traumatic orbital hemorrhage without underlying vascular malformations or predisposing conditions is uncommon, and particularly rare in the context of maternal labor. This study combines a novel case report and retrospective review to analyze reported cases and propose insights.
    Methods: This study is both a unique case report and literature review examining PubMed publications with articles traced back to original sources through citations for inclusion. Analysis included clinical presentation, visual examination, hematoma characteristics, neuroimaging, management strategies, and outcomes.
    Results: We present a 37-year-old multigravida woman at 40 weeks gestation who developed acute right-sided proptosis, diplopia, retrobulbar pain, and periorbital edema during the second stage of labor. Computed tomography (CT) revealed a subperiosteal hemorrhage, with subsequent magnetic resonance imaging (MRI) excluding vascular anomalies. Symptoms resolved within two months. Only 14 cases of maternal orbital hematoma associated with labor have been reported. The average age was 28 with 42% (6/14) being primigravid. Including our case, forty percent (6/15) developed symptoms during the second stage of labor, 40% (6/15) immediately postpartum, and 20% (3/15) over 24 hours postpartum. Overall, 33% (5/15) had potentially contributing conditions including coagulopathies, delivery complications, or vascular malformations. Unilateral orbital hemorrhage occurred in 87% (13/15). Surgical intervention was necessary in 13% (2/15). Most (87%, 13/15) underwent observation or medical management with full recovery of symptoms.
    Conclusions: Non-traumatic orbital hematomas associated with maternal labor are rare and likely related to increased valsalva during delivery and heightened blood volume in pregnancy. Neuro-imaging and systemic workup are recommended to assess for vascular anomalies or underlying coagulopathies. The overall prognosis is favorable with most having full recovery.
    MeSH term(s) Humans ; Female ; Adult ; Pregnancy ; Hematoma/diagnosis ; Hematoma/etiology ; Tomography, X-Ray Computed ; Magnetic Resonance Imaging ; Orbital Diseases/diagnosis ; Orbital Diseases/etiology ; Obstetric Labor Complications/diagnosis ; Labor, Obstetric ; Parturition
    Language English
    Publishing date 2024-04-26
    Publishing country Netherlands
    Document type Journal Article ; Case Reports ; Review
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-024-03149-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Survey of state conjunctivitis policies for school-age students.

    Lee, Tracy / Kuo, Irene C

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus

    2022  Volume 26, Issue 3, Page(s) 115.e1–115.e5

    Abstract: Purpose: To examine state policies regarding school-age students with conjunctivitis.: Methods: Analysis included the following evidence: publicly available policies for disposition of affected students; indications for exclusion and return to ... ...

    Abstract Purpose: To examine state policies regarding school-age students with conjunctivitis.
    Methods: Analysis included the following evidence: publicly available policies for disposition of affected students; indications for exclusion and return to classroom; and completeness of information, including mention of different etiologies of conjunctivitis; signs and symptoms of viral versus bacterial conjunctivitis; student disposition and treatment based on etiology; internally consistent recommendations; reference to credible resources; and mention of the possibility of a conjunctivitis outbreak.
    Results: Fifteen of 50 states have no policies. Ten states allow students to remain in school, 5 allow return 24 hours after initiation of antibiotic treatment, and 5 require physician approval. Seventeen states and Washington, DC, offer little detail or internally inconsistent recommendations, such as choice of antibiotic use or provider note. Twelve policies are thoroughly presented. Twenty-three states refer to sources like the Centers for Disease Control and Prevention and the American Academy of Pediatrics. No policy references the American Academy of Ophthalmology.
    Conclusions: State policies on conjunctivitis in students vary widely. Antibiotic use as a prerequisite for return to school has drawbacks of cost to parents, increasing antibiotic resistance, and lack of efficacy against nonbacterial etiologies, for example, viral conjunctivitis. Publicly available information and guidelines could be improved, aiming for fewer absentee days, reduced outbreak risk, and reduced risk of antibiotic resistance.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Child ; Conjunctivitis ; Humans ; Schools ; Students ; Surveys and Questionnaires ; United States/epidemiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1412476-2
    ISSN 1528-3933 ; 1091-8531
    ISSN (online) 1528-3933
    ISSN 1091-8531
    DOI 10.1016/j.jaapos.2022.02.002
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  10. Article ; Online: Chemical Tools to Image the Activity of PAR-Cleaving Proteases.

    Lee, Irene Y / Tantisirivat, Piyapa / Edgington-Mitchell, Laura E

    ACS bio & med chem Au

    2023  Volume 3, Issue 4, Page(s) 295–304

    Abstract: Protease-activated receptors (PARs) comprise a family of four G protein-coupled receptors (GPCRs) that have broad functions in health and disease. Unlike most GPCRs, PARs are uniquely activated by proteolytic cleavage of their extracellular N termini. To ...

    Abstract Protease-activated receptors (PARs) comprise a family of four G protein-coupled receptors (GPCRs) that have broad functions in health and disease. Unlike most GPCRs, PARs are uniquely activated by proteolytic cleavage of their extracellular N termini. To fully understand PAR activation and function in vivo, it is critical to also study the proteases that activate them. As proteases are heavily regulated at the post-translational level, measures of total protease abundance have limited utility. Measures of protease activity are instead required to inform their function. This review will introduce several classes of chemical probes that have been developed to measure the activation of PAR-cleaving proteases. Their strengths, weaknesses, and applications will be discussed, especially as applied to image protease activity at the whole organism, tissue, and cellular level.
    Language English
    Publishing date 2023-05-27
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2694-2437
    ISSN (online) 2694-2437
    DOI 10.1021/acsbiomedchemau.3c00019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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