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  1. Article ; Online: Genome-Wide Identification of the

    Fan, Jiaming / Deng, Minjie / Li, Bingbing / Fan, Guoqiang

    International journal of molecular sciences

    2024  Volume 25, Issue 4

    Abstract: The typical symptom of Paulownia witches' broom (PaWB), caused by phytoplasma infection, is excessive branching, which is mainly triggered by auxin metabolism disorder. ...

    Abstract The typical symptom of Paulownia witches' broom (PaWB), caused by phytoplasma infection, is excessive branching, which is mainly triggered by auxin metabolism disorder.
    MeSH term(s) Phytoplasma/genetics ; Cytisus ; Phylogeny ; Lamiales/genetics ; Indoleacetic Acids
    Chemical Substances Indoleacetic Acids
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25042260
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  2. Article ; Online: New-onset pemphigus foliaceus after COVID-19 infection.

    Xie, Yihang / Yang, Mei / Zhou, Peimei / Fan, Jiaming / Zhou, Sijie

    Journal of medical virology

    2023  Volume 95, Issue 6, Page(s) e28867

    MeSH term(s) Humans ; Pemphigus/complications ; COVID-19/complications
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28867
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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  3. Article ; Online: High-precision time measurement electronics using the bandpass sampling method.

    Fan, Yichun / Zhao, Lei / Qin, Jiajun / Li, Jiaming / Huang, Shiya / Cao, Zhe

    The Review of scientific instruments

    2024  Volume 95, Issue 1

    Abstract: Waveform digitization at sampling rates up to several giga-samples per second is one of the approaches to achieve high-precision time measurements. In recent years, achieving high precision at lower sampling rates has emerged as a significant research ... ...

    Abstract Waveform digitization at sampling rates up to several giga-samples per second is one of the approaches to achieve high-precision time measurements. In recent years, achieving high precision at lower sampling rates has emerged as a significant research topic. In this article, we focus on time measurement electronics, in which the bandpass sampling method is applied to obtain high precision at a sampling rate of roughly 100 MSps. An analog front-end circuit is designed, in which the input pulse signal is bandpass-filtered and amplified before sampling. A pipelined real-time time extraction algorithm is designed using the techniques of interpolation and cross correlation. A 1024-point fast Fourier transform algorithm is adopted to implement the cross correlation operation. Four time measurement channels are implemented in a mid-range field-programmable gate array, and the measurement rate of 116 kHz is achieved. Tests are conducted to evaluate the performance of the timing system. The typical RMS precision is better than 0.4 ps.
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209865-9
    ISSN 1089-7623 ; 0034-6748
    ISSN (online) 1089-7623
    ISSN 0034-6748
    DOI 10.1063/5.0178312
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  4. Article: [A review on electroencephalogram based channel selection].

    Li, Xiangzhe / Wang, Dan / Zhang, Baiwen / Fan, Chaojie / Chen, Jiaming / Xu, Meng / Chen, Yuanfang

    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi

    2024  Volume 41, Issue 2, Page(s) 398–405

    Abstract: The electroencephalogram (EEG) signal is the key signal carrier of the brain-computer interface (BCI) system. The EEG data collected by the whole-brain electrode arrangement is conducive to obtaining higher information representation. Personalized ... ...

    Abstract The electroencephalogram (EEG) signal is the key signal carrier of the brain-computer interface (BCI) system. The EEG data collected by the whole-brain electrode arrangement is conducive to obtaining higher information representation. Personalized electrode layout, while ensuring the accuracy of EEG signal decoding, can also shorten the calibration time of BCI and has become an important research direction. This paper reviews the EEG signal channel selection methods in recent years, conducts a comparative analysis of the combined effects of different channel selection methods and different classification algorithms, obtains the commonly used channel combinations in motor imagery, P300 and other paradigms in BCI, and explains the application scenarios of the channel selection method in different paradigms are discussed, in order to provide stronger support for a more accurate and portable BCI system.
    MeSH term(s) Electroencephalography ; Brain-Computer Interfaces ; Humans ; Algorithms ; Signal Processing, Computer-Assisted ; Brain/physiology ; Electrodes ; Event-Related Potentials, P300/physiology ; Imagination/physiology
    Language Chinese
    Publishing date 2024-04-15
    Publishing country China
    Document type Journal Article ; Review ; English Abstract
    ZDB-ID 2576847-5
    ISSN 1001-5515
    ISSN 1001-5515
    DOI 10.7507/1001-5515.202308034
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6887: Show issues Location:
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  5. Article ; Online: Vitamin D deficiency increases the risk of diabetic peripheral neuropathy in elderly type 2 diabetes mellitus patients by predominantly increasing large-fiber lesions.

    Fei, Sijia / Fan, Jingwen / Cao, Jiaming / Chen, Huan / Wang, Xiaoxia / Pan, Qi

    Diabetes research and clinical practice

    2024  Volume 209, Page(s) 111585

    Abstract: Aims: This study explores the link between Vitamin D deficiency (VDD) and diabetic peripheral neuropathy (DPN) in elderly type 2 diabetes mellitus (T2DM) patients.: Methods: Involving 257 elderly T2DM patients, the study utilized propensity score ... ...

    Abstract Aims: This study explores the link between Vitamin D deficiency (VDD) and diabetic peripheral neuropathy (DPN) in elderly type 2 diabetes mellitus (T2DM) patients.
    Methods: Involving 257 elderly T2DM patients, the study utilized propensity score matching to balance age, sex, and diabetes duration. VDD was defined as serum 25-hydroxyvitamin D [25(OH)D] levels below 20 ng/ml. Large nerve fiber lesions were evaluated by electromyogram, while small nerve fiber lesions were assessed by measuring skin conductance.
    Results: DPN patients had notably lower serum 25(OH)D levels than non-DPN patients [15.05 vs. 18.4 ng/ml, P = 0.018]. VDD was identified as an independent risk factor for DPN (odds ratio = 2.488, P = 0.008) in multivariate logistic regression analysis. Spearman's correlation showed negative correlations between serum 25(OH)D levels and specific nerve latencies, and positive correlations with specific nerve velocities and amplitudes. The VDD group exhibited longer median sensory nerve latencies and motor evoked potential latencies compared to the vitamin D-sufficient group. Further, VDD is associated with the prolongation of the median motor nerve latency (odds ratio = 1.362, P = 0.038).
    Conclusions: VDD is independently associated with a higher risk of DPN. VDD may promote the development of DPN by affecting large nerve fibers.
    MeSH term(s) Humans ; Aged ; Diabetes Mellitus, Type 2 ; Diabetic Neuropathies ; Vitamin D Deficiency/complications ; Risk Factors ; Vitamin D ; Nerve Fibers
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2024-02-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2024.111585
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2047: Show issues Location:
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  6. Article ; Online: Corrigendum: Biologically inspired swimming robotic frog based on pneumatic soft actuators (2020

    Fan, Jizhuang / Du, Qilong / Yu, Qingguo / Wang, Yi / Qi, Jiaming / Zhu, Yanhe

    Bioinspiration & biomimetics

    2022  Volume 17, Issue 4

    Language English
    Publishing date 2022-05-23
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 2235670-8
    ISSN 1748-3190 ; 1748-3182
    ISSN (online) 1748-3190
    ISSN 1748-3182
    DOI 10.1088/1748-3190/ac65cb
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  7. Article ; Online: A case of dupilumab-induced reverse psoriasis in a patient with atopic dermatitis.

    Fan, Jiaming / Zhang, Liwen / Lu, Yonghong / Zhou, Peimei

    Dermatologic therapy

    2022  Volume 35, Issue 4, Page(s) e15345

    MeSH term(s) Antibodies, Monoclonal, Humanized/adverse effects ; Dermatitis, Atopic/diagnosis ; Dermatitis, Atopic/drug therapy ; Eczema ; Humans ; Psoriasis/diagnosis ; Psoriasis/drug therapy
    Chemical Substances Antibodies, Monoclonal, Humanized ; dupilumab (420K487FSG)
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.15345
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5181: Show issues Location:
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  8. Article ; Online: miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis.

    Nan, Li / Kaisi, Fan / Mengzhen, Zhang / Yang, Yang / Jiaming, Yang / Huirong, Yang / Xinwei, Hou / Chen, Wang / Liucheng, Yang / Kai, Wu

    Pediatric surgery international

    2024  Volume 40, Issue 1, Page(s) 63

    Abstract: Purpose: Necrotizing enterocolitis (NEC) is a significant contributor to neonatal mortality. This study aimed to investigate the role of high levels of miR-375-3p in breast milk in the development of NEC and elucidate its mechanism.: Methods: ... ...

    Abstract Purpose: Necrotizing enterocolitis (NEC) is a significant contributor to neonatal mortality. This study aimed to investigate the role of high levels of miR-375-3p in breast milk in the development of NEC and elucidate its mechanism.
    Methods: Differential expression of miR-375-3p in the intestines of breast-fed and formula-fed mice was confirmed using real-time polymerase chain reaction (RT-PCR). NEC mice models were established, and intestinal injury was assessed using HE staining. RT-PCR and Western blot were conducted to examine the expression of miR-375-3p, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein β (YWHAB), as well as the inflammatory in IEC-6 cells, and intestinal tissues obtained from NEC mice and patients. Flow cytometry and cell counting kit-8 (CCK-8) were employed to elucidate the impact of miR-375-3p and YWHAB on cell apoptosis and proliferation.
    Results: Breastfeeding increases miR-375-3p expression in the intestines. The expression of miR-375-3p in NEC intestinal tissues exhibited a significant decrease compared to the healthy group. Additionally, the expression of interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-α (TNF-α) was higher in the NEC group compared to the control group. Down-regulation of miR-375-3p inhibited IEC-6 cell proliferation, increased apoptosis, and elevated secretion of inflammatory factors. Bioinformatics revealed that YWHAB may be a target of miR-375-3p. RT-PCR and Western blot indicated a down-regulation of YWHAB expression in intestines of NEC patients and mice. Furthermore, YWHAB was found to be positively connected with miR-375-3p. Knockdown miR-375-3p down-regulated YWHAB expression in cells. Inhibition of YWHAB exhibited similar effects to miR-375-3p in IEC-6 cells. YWHAB plasmid partially reverse cellular functional impairment induced by miR-375-3p knockdown.
    Conclusions: Breastfeeding elevated miR-375-3p expression in intestines in neonatal mice. MiR-375-3p leads to a decrease in apoptosis of intestinal epithelial cells, an increase in cell proliferation, and a concomitant reduction in the expression of inflammatory factors partly through targeting YWHAB.
    MeSH term(s) Animals ; Female ; Humans ; Infant, Newborn ; Mice ; 14-3-3 Proteins/metabolism ; Abdominal Injuries ; Enterocolitis, Necrotizing/metabolism ; Fetal Diseases ; Infant, Newborn, Diseases ; MicroRNAs/genetics
    Chemical Substances 14-3-3 Proteins ; MicroRNAs ; MIRN375 microRNA, human ; YWHAB protein, human
    Language English
    Publishing date 2024-03-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-024-05653-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2138: Show issues Location:
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  9. Article: A Distinct Glucose Metabolism Signature of Lung Adenocarcinoma With Prognostic Value.

    Li, Ding / Liang, Jiaming / Zhang, Wenzhou / Wu, Xuan / Fan, Jie

    Frontiers in genetics

    2022  Volume 13, Page(s) 860677

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-05-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.860677
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  10. Article ; Online: Pyrvinium doubles against WNT-driven cancer.

    Fan, Jiaming / Reid, Russell R / He, Tong-Chuan

    The Journal of biological chemistry

    2022  Volume 298, Issue 10, Page(s) 102479

    Abstract: The WNT-β-catenin signaling pathway has a major role in regulating cell proliferation and differentiation. Aberrant activation of the pathway contributes to various human cancer types. Because casein kinase CK1α-initiated phosphorylation of β-catenin is ... ...

    Abstract The WNT-β-catenin signaling pathway has a major role in regulating cell proliferation and differentiation. Aberrant activation of the pathway contributes to various human cancer types. Because casein kinase CK1α-initiated phosphorylation of β-catenin is a key first step to restrain WNT signaling, effective restoration of CK1α activity represents an innovative strategy to combat WNT-driven cancer. A recent study in JBC reveals the anthelmintic pyrvinium directly binds to CK1α as an activator and also stabilizes CK1α protein, doubling against WNT-driven cancer activity.
    MeSH term(s) Humans ; beta Catenin/genetics ; beta Catenin/metabolism ; Pyrvinium Compounds/pharmacology ; Wnt Signaling Pathway ; Neoplasms/drug therapy ; Neoplasms/genetics
    Chemical Substances pyrvinium (6B9991FLU3) ; beta Catenin ; Pyrvinium Compounds
    Language English
    Publishing date 2022-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2022.102479
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    Uc I Zs.108: Show issues Location:
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