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  1. Article ; Online: Effects of statins on clinical outcomes in hospitalized patients with COVID-19.

    Martins-Filho, Paulo Ricardo / Barreto-Filho, José Augusto Soares / Sousa, Antônio Carlos Sobral

    European journal of internal medicine

    2022  Volume 104, Page(s) 113–115

    MeSH term(s) COVID-19 ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; SARS-CoV-2
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2022-06-09
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2022.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2608: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Myocardial Injury Biomarkers and Cardiac Complications Associated with Mortality in Patients with COVID-19.

    Martins-Filho, Paulo Ricardo / Barreto-Filho, José Augusto Soares / Santos, Victor Santana

    Arquivos brasileiros de cardiologia

    2020  Volume 115, Issue 2, Page(s) 273–277

    Abstract: Background: SARS-CoV-2 is an emerging RNA virus associated with a severe acute respiratory disease known as COVID-19. Although COVID-19 is predominantly a pulmonary disease, some patients have severe cardiovascular damage. We performed a quantitative ... ...

    Title translation Biomarcadores de Lesão Miocárdica e Complicações Cardíacas Associadas à Mortalidade em Pacientes com COVID-19.
    Abstract Background: SARS-CoV-2 is an emerging RNA virus associated with a severe acute respiratory disease known as COVID-19. Although COVID-19 is predominantly a pulmonary disease, some patients have severe cardiovascular damage. We performed a quantitative evidence synthesis of clinical data, myocardial injury biomarkers, and cardiac complications associated with in-hospital death in patients with COVID-19.
    Methods: We searched the databases PubMed, Embase, and Google Scholar to identify studies comparing clinical data, myocardial injury biomarkers, and cardiac complications between non-survivors and survivors of COVID-19. Effect sizes were reported as mean difference or standardized mean difference for continuous variables and risk ratio for dichotomous variables with 95% confidence intervals. A random effects model was used to pool the results.
    Results: Six retrospective studies reporting data from 1,141 patients (832 survivors and 309 non-survivors) were included. We found that underlying cardiovascular conditions; elevation of high-sensitivity cardiac troponin I, N-terminal pro-B-type natriuretic peptide, and creatine kinase-MB; and cardiac complications were associated with increased risk of death for patients with SARS-CoV-2 infection.
    Conclusions: The confirmation that underlying cardiovascular conditions, elevation of myocardial injury biomarkers during COVID-19 infection, and acute cardiovascular decompensation are predictors for mortality in SARS-CoV-2 infection must encourage new research to clarify potential mechanisms and test appropriate treatments. (Arq Bras Cardiol. 2020; 115(2):273-277).
    MeSH term(s) Betacoronavirus ; Biomarkers/blood ; COVID-19 ; Cardiovascular Diseases/mortality ; Cardiovascular Diseases/virology ; Coronavirus Infections/complications ; Coronavirus Infections/mortality ; Humans ; Myocardium/pathology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/mortality ; Retrospective Studies ; SARS-CoV-2
    Chemical Substances Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-10-23
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20200372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 548: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: COVID-19 and Uncertainty: Lessons from the Frontline for Promoting Shared Decision Making.

    Barreto-Filho, José Augusto Soares / Veiga, André / Correia, Luis Claudio

    Arquivos brasileiros de cardiologia

    2020  Volume 115, Issue 2, Page(s) 149–151

    Title translation COVID-19 e Incertezas: Lições do Frontline para a Promoção da Decisão Compartilhada.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/psychology ; Decision Making, Shared ; Humans ; Pandemics ; Patient Participation ; Pneumonia, Viral/psychology ; SARS-CoV-2 ; Uncertainty
    Keywords covid19
    Language English
    Publishing date 2020-08-29
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20200582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 548: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article: Cardiovascular health control in the family health strategy.

    Tavares, Gilberto Andrade / Ribeiro, Joathan Borges / Almeida-Santos, Marcos Antonio / Sousa, Antônio Carlos Sobral / Barreto-Filho, José Augusto Soares

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 933972

    Abstract: Introduction: In Brazil, the Unified Health System (SUS) controls and oversees public health care, and the Family Health Strategy (FHS) is its primary access, with 60% of the population registered in it. The surveillance of risk factors for ... ...

    Abstract Introduction: In Brazil, the Unified Health System (SUS) controls and oversees public health care, and the Family Health Strategy (FHS) is its primary access, with 60% of the population registered in it. The surveillance of risk factors for cardiovascular diseases (CVD) is the responsibility of the FHS. In 2010, the American Heart Association (AHA) proposed the evaluation of seven metrics (smoking, Body Mass Index (BMI), physical activity, diet, total cholesterol, blood pressure and blood glucose) with an aim to monitoring cardiovascular health (CVH). However, the results of the FHS regarding the CVH of the Brazilian population are unascertained.
    Objective: Evaluate the control of CVH among adult patients treated by the FHS in the city of Aracaju, Sergipe, Brazil.
    Material and methods: A cross-sectional study was conducted using the seven metrics recommended by the AHA to evaluate CVH among patients treated by the FHS. The city of Aracaju has a population of 571,149 inhabitants, with 394,267 > 20 years of age; therefore, it was admitted that in a simple random sample, sampling error of 5% with 95% CI, 329 individuals would be needed.
    Results: Among 400 patients, only 32.5% had controlled CVH. In a univariate analysis, the adjusted multivariate analysis found that being female (aOR: 2.07 IC: 1.20 to 3.60
    Conclusions: The study showed that only 32.5% of patients have controlled CVH. Being a woman, young and following health advice from family members and neighbors have a positive influence in controlling CVH. More children reduced controlling these metrics.
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.933972
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  5. Article ; Online: Reply to Nuschke and Haouzi.

    Barreto-Filho, José Augusto / Seabra-Garcez, Juliane Dantas / Garcez, Flavia Barreto / Moreira, Thiago S / Drager, Luciano F

    Journal of applied physiology (Bethesda, Md. : 1985)

    2021  Volume 131, Issue 3, Page(s) 1136–1137

    Language English
    Publishing date 2021-09-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00556.2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.249: Show issues Location:
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  6. Article ; Online: Potential of Family Health Strategy Against Cardiovascular Disease.

    Tavares, Gilberto Andrade / Barreto-Filho, José Augusto Soares

    Arquivos brasileiros de cardiologia

    2017  Volume 109, Issue 6, Page(s) 507–508

    MeSH term(s) Brazil/epidemiology ; Cardiovascular Diseases/prevention & control ; Family Health ; Government Programs ; Humans ; Primary Health Care
    Language Portuguese
    Publishing date 2017
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.5935/abc.20170187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 548: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Biomarcadores de Lesão Miocárdica e Complicações Cardíacas Associadas à Mortalidade em Pacientes com COVID-19./ Biomarcadores de Lesão Miocárdica e Complicações Cardíacas Associadas à Mortalidade em Pacientes com COVID-19./ Myocardial Injury Biomarkers and Cardiac Complications Associated with Mortality in Patients with COVID-19

    Martins-Filho, Paulo Ricardo / Barreto-Filho, José Augusto Soares / Santos, Victor Santana

    Arq Bras Cardiol

    Abstract: BACKGROUND: SARS-CoV-2 is an emerging RNA virus associated with a severe acute respiratory disease known as COVID-19. Although COVID-19 is predominantly a pulmonary disease, some patients have severe cardiovascular damage. We performed a quantitative ... ...

    Abstract BACKGROUND: SARS-CoV-2 is an emerging RNA virus associated with a severe acute respiratory disease known as COVID-19. Although COVID-19 is predominantly a pulmonary disease, some patients have severe cardiovascular damage. We performed a quantitative evidence synthesis of clinical data, myocardial injury biomarkers, and cardiac complications associated with in-hospital death in patients with COVID-19. METHODS: We searched the databases PubMed, Embase, and Google Scholar to identify studies comparing clinical data, myocardial injury biomarkers, and cardiac complications between non-survivors and survivors of COVID-19. Effect sizes were reported as mean difference or standardized mean difference for continuous variables and risk ratio for dichotomous variables with 95% confidence intervals. A random effects model was used to pool the results. RESULTS: Six retrospective studies reporting data from 1,141 patients (832 survivors and 309 non-survivors) were included. We found that underlying cardiovascular conditions; elevation of high-sensitivity cardiac troponin I, N-terminal pro-B-type natriuretic peptide, and creatine kinase-MB; and cardiac complications were associated with increased risk of death for patients with SARS-CoV-2 infection. CONCLUSIONS: The confirmation that underlying cardiovascular conditions, elevation of myocardial injury biomarkers during COVID-19 infection, and acute cardiovascular decompensation are predictors for mortality in SARS-CoV-2 infection must encourage new research to clarify potential mechanisms and test appropriate treatments. (Arq Bras Cardiol. 2020; 115(2):273-277).
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #740655
    Database COVID19

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  8. Article: COVID-19 e Incertezas: Lições do Frontline para a Promoção da Decisão Compartilhada./ COVID-19 e Incertezas: Lições do Frontline para a Promoção da Decisão Compartilhada./ COVID-19 and Uncertainty: Lessons from the Frontline for Promoting Shared Decision Making

    Barreto-Filho, José Augusto Soares / Veiga, André / Correia, Luis Claudio

    Arq Bras Cardiol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #740659
    Database COVID19

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  9. Article ; Online: Nondyspnogenic acute hypoxemic respiratory failure in COVID-19 pneumonia.

    Barreto-Filho, José Augusto / Seabra-Garcez, Juliane Dantas / Garcez, Flavia Barreto / Moreira, Thiago S / Drager, Luciano F

    Journal of applied physiology (Bethesda, Md. : 1985)

    2020  Volume 130, Issue 3, Page(s) 892–897

    MeSH term(s) COVID-19/complications ; COVID-19/virology ; Humans ; Pneumonia, Viral/complications ; Pneumonia, Viral/virology ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/virology ; SARS-CoV-2/pathogenicity
    Keywords covid19
    Language English
    Publishing date 2020-10-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00522.2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.249: Show issues Location:
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  10. Article: Insights into the actions of angiotensin-1 receptor (AT1R) inverse agonists: Perspectives and implications in COVID-19 treatment.

    Heimfarth, Luana / Dos Santos, Mario Adriano / Barreto-Filho, José Augusto / Barreto, André Sales / Macedo, Fabrício Nunes / Araújo, Adriano Antunes de Souza / Martins-Filho, Paulo / Scotti, Marcus Tullius / Scotti, Luciana / Quintans-Júnior, Lucindo José

    EXCLI journal

    2021  Volume 20, Page(s) 252–275

    Abstract: New coronavirus SARS-CoV-2 (COVID-19) has caused chaos in health care systems. Clinical manifestations of COVID-19 are variable, with a complex pathophysiology and as yet no specific treatment. It has been suggested that the renin-angiotensin-aldosterone ...

    Abstract New coronavirus SARS-CoV-2 (COVID-19) has caused chaos in health care systems. Clinical manifestations of COVID-19 are variable, with a complex pathophysiology and as yet no specific treatment. It has been suggested that the renin-angiotensin-aldosterone system has a possible role in the severity of cases and the number of deaths. Our hypothesis is that drugs with inverse agonist effects to the angiotensin-1 receptor can be promising tools in the management of patients with COVID-19, possibly avoiding complications and the poor evolution in some cases. Any risk factors first need to be identified, and the most appropriate time to administer the drugs during the course of the infection also needs to be established. Several angiotensin receptor blockers (ARB) have a favorable profile and are important candidates for the treatment of COVID-19. In this review we discussed a set of compounds with favorable profile for COVID-19 treatment, including azilsartan, candesartan, eprosartan, EXP3174, olmesartan, telmisartan, and valsartan. They are effective as inverse agonists and could reduce the "cytokine storm" and reducing oxidative stress. As COVID-19 disease has several evolution patterns, the effectiveness of ARB therapy would be related to infection "timing", patient risk factors, previous use of ARBs, and the specific molecular effects of an ARB. However, controlled studies are needed to identify whether ARBs are beneficial in the treatment of patients with COVID-19.
    Language English
    Publishing date 2021-02-08
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 1611-2156
    ISSN 1611-2156
    DOI 10.17179/excli2021-3412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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