LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 112

Search options

  1. Article ; Online: Short-term periods of strenuous physical activity lower iron absorption.

    Brittenham, Gary M

    The American journal of clinical nutrition

    2021  Volume 113, Issue 2, Page(s) 261–262

    MeSH term(s) Cross-Over Studies ; Exercise ; Hepcidins ; Humans ; Iron ; Iron, Dietary
    Chemical Substances Hepcidins ; Iron, Dietary ; Iron (E1UOL152H7)
    Language English
    Publishing date 2021-03-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1093/ajcn/nqaa365
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Iron.

    Brittenham, Gary M / Fairweather-Tait, Susan

    Advances in nutrition (Bethesda, Md.)

    2023  Volume 14, Issue 5, Page(s) 1241–1243

    MeSH term(s) Humans ; Iron
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2583634-1
    ISSN 2156-5376 ; 2156-5376
    ISSN (online) 2156-5376
    ISSN 2156-5376
    DOI 10.1016/j.advnut.2023.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: How I treat anemia with red blood cell transfusion and iron.

    Carson, Jeffrey L / Brittenham, Gary M

    Blood

    2022  Volume 142, Issue 9, Page(s) 777–785

    Abstract: Severe anemia is commonly treated with red blood cell transfusion. Clinical trials have demonstrated that a restrictive transfusion strategy of 7 to 8 g/dL is as safe as a liberal transfusion strategy of 9 to 10 g/dL in many clinical settings. Evidence ... ...

    Abstract Severe anemia is commonly treated with red blood cell transfusion. Clinical trials have demonstrated that a restrictive transfusion strategy of 7 to 8 g/dL is as safe as a liberal transfusion strategy of 9 to 10 g/dL in many clinical settings. Evidence is lacking for subgroups of patients, including those with preexisting coronary artery disease, acute myocardial infarction, congestive heart failure, and myelodysplastic neoplasms. We present 3 clinical vignettes that highlight the clinical challenges in caring for patients with coronary artery disease with gastrointestinal bleeding, congestive heart failure, or myelodysplastic neoplasms. We emphasize that transfusion practice should be guided by patient symptoms and preferences in conjunction with the patient's hemoglobin concentration. Along with the transfusion decision, evaluation and management of the etiology of the anemia is essential. Iron-restricted erythropoiesis is a common cause of anemia severe enough to be considered for red blood cell transfusion but diagnosis and management of absolute iron deficiency anemia, the anemia of inflammation with functional iron deficiency, or their combination may be problematic. Intravenous iron therapy is generally the treatment of choice for absolute iron deficiency in patients with complex medical disorders, with or without coexisting functional iron deficiency.
    MeSH term(s) Humans ; Iron/therapeutic use ; Erythrocyte Transfusion/adverse effects ; Coronary Artery Disease/complications ; Anemia/etiology ; Anemia/therapy ; Anemia, Iron-Deficiency/complications ; Anemia, Iron-Deficiency/therapy ; Myelodysplastic Syndromes/complications ; Heart Failure/therapy ; Heart Failure/complications ; Neoplasms/complications ; Hemoglobins/analysis
    Chemical Substances Iron (E1UOL152H7) ; Hemoglobins
    Language English
    Publishing date 2022-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2022018521
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 364: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Risks for Anaphylaxis With Intravenous Iron Formulations.

    Dave, Chintan V / Brittenham, Gary M / Carson, Jeffrey L / Setoguchi, Soko

    Annals of internal medicine

    2022  Volume 175, Issue 11, Page(s) W143–W144

    MeSH term(s) Humans ; Anaphylaxis/chemically induced ; Iron/adverse effects ; Drug Hypersensitivity
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2022-10-28
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L22-0283
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.178/2: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Iron Deficiency in Chronic Pediatric Heart Failure: Overall Assessment and Outcomes in Dilated Cardiomyopathy.

    Phillips, Lia / Richmond, Marc / Neunert, Cindy / Jin, Zhezhen / Brittenham, Gary M

    The Journal of pediatrics

    2023  Volume 263, Page(s) 113721

    Abstract: Objective: To evaluate the frequency of iron status assessment in pediatric heart failure and the prevalence and adverse effects of absolute iron deficiency in dilated cardiomyopathy-induced heart failure.: Study design: We retrospectively reviewed ... ...

    Abstract Objective: To evaluate the frequency of iron status assessment in pediatric heart failure and the prevalence and adverse effects of absolute iron deficiency in dilated cardiomyopathy-induced heart failure.
    Study design: We retrospectively reviewed records of children with chronic heart failure at our center between 2010 and 2020. In children with dilated cardiomyopathy, we analyzed baseline cardiac function, hemoglobin level, and subsequent risk of composite adverse events (CAE), including death, heart transplant, ventricular assist device (VAD) placement, and transplant registry listing. Absolute iron deficiency and iron sufficiency were defined as transferrin saturations <20% and ≥30%, respectively; and indeterminant iron status as 20%-29%.
    Results: Of 799 patients with chronic heart failure, 471 (59%) had no iron-related laboratory measurements. Of 68 children with dilated cardiomyopathy, baseline transferrin saturation, and quantitative left ventricular ejection fraction (LVEF), 33 (49%) and 14 (21%) were iron deficient and sufficient, respectively, and 21 (31%) indeterminant. LVEF was reduced to 23.6 ± 12.1% from 32.9 ± 16.8% in iron deficiency and sufficiency, respectively (P = .04), without a significant difference in hemoglobin. After stratification by New York Heart Association classification, in advanced class IV, hemoglobin was reduced to 10.9 ± 1.3 g/dL vs 12.7 ± 2.0 g/dL in iron deficiency and sufficiency, respectively (P = .01), without a significant difference in LVEF.
    Conclusions: In this single-center study, iron deficiency was not monitored in most children with chronic heart failure. In pediatric dilated cardiomyopathy-induced heart failure, absolute iron deficiency was prevalent and associated with clinically consequential and possibly correctable decreases in cardiac function and hemoglobin concentration.
    MeSH term(s) Humans ; Child ; Cardiomyopathy, Dilated/complications ; Cardiomyopathy, Dilated/therapy ; Stroke Volume ; Retrospective Studies ; Ventricular Function, Left ; Heart Failure/complications ; Heart Failure/therapy ; Iron Deficiencies ; Iron/pharmacology ; Chronic Disease ; Hemoglobins ; Transferrins/pharmacology
    Chemical Substances Iron (E1UOL152H7) ; Hemoglobins ; Transferrins
    Language English
    Publishing date 2023-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2023.113721
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Reference method for measurement of the hepatic iron concentration.

    Brittenham, Gary M

    American journal of hematology

    2015  Volume 90, Issue 2, Page(s) 85–86

    MeSH term(s) Biopsy, Needle/standards ; Female ; Humans ; Iron/metabolism ; Iron Overload/metabolism ; Liver/metabolism ; Male ; Thalassemia/metabolism
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2015-02
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.23914
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Detecting anaemia at high altitude.

    Sarna, Kaylee / Brittenham, Gary M / Beall, Cynthia M

    Evolution, medicine, and public health

    2020  Volume 2020, Issue 1, Page(s) 68–69

    Language English
    Publishing date 2020-04-13
    Publishing country England
    Document type Case Reports
    ZDB-ID 2684837-5
    ISSN 2050-6201
    ISSN 2050-6201
    DOI 10.1093/emph/eoaa011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Risks for Anaphylaxis With Intravenous Iron Formulations : A Retrospective Cohort Study.

    Dave, Chintan V / Brittenham, Gary M / Carson, Jeffrey L / Setoguchi, Soko

    Annals of internal medicine

    2022  Volume 175, Issue 5, Page(s) 656–664

    Abstract: Background: The risks for anaphylaxis among intravenous (IV) iron products currently in use have not been assessed.: Objective: To compare risks for anaphylaxis among 5 IV iron products that are used frequently.: Design: Retrospective cohort study ...

    Abstract Background: The risks for anaphylaxis among intravenous (IV) iron products currently in use have not been assessed.
    Objective: To compare risks for anaphylaxis among 5 IV iron products that are used frequently.
    Design: Retrospective cohort study using a target trial emulation framework.
    Setting: Medicare fee-for-service data with Part D coverage between July 2013 and December 2018.
    Participants: Older adults receiving their first administration of IV iron.
    Measurements: The primary outcome was the occurrence of anaphylaxis within 1 day of IV iron administration, ascertained using a validated case definition. Analysis was adjusted for 40 baseline covariates using inverse probability of treatment weighting. The adjusted incidence rates (IRs) for anaphylaxis per 10 000 first administrations and odds ratios (ORs) were computed.
    Results: The adjusted IRs for anaphylaxis per 10 000 first administrations were 9.8 cases (95% CI, 6.2 to 15.3 cases) for iron dextran, 4.0 cases (CI, 2.5 to 6.6 cases) for ferumoxytol, 1.5 cases (CI, 0.3 to 6.6 cases) for ferric gluconate, 1.2 cases (CI, 0.6 to 2.5 cases) for iron sucrose, and 0.8 cases (CI, 0.3 to 2.6 cases) for ferric carboxymaltose. Using iron sucrose as the referent category, the adjusted ORs for anaphylaxis were 8.3 (CI, 3.5 to 19.8) for iron dextran and 3.4 (CI, 1.4 to 8.3) for ferumoxytol. When cohort entry was restricted to the period after withdrawal of high-molecular-weight iron dextran from the U.S. market in 2014, the risk for anaphylaxis associated with low-molecular-weight iron dextran (OR, 8.4 [CI, 2.8 to 24.7]) did not change appreciably. Anaphylactic reactions requiring hospitalizations were observed only among patients using iron dextran or ferumoxytol.
    Limitation: Generalizability to non-Medicare populations.
    Conclusion: The rates of anaphylaxis were very low with all IV iron products but were 3- to 8-fold greater for iron dextran and ferumoxytol than for iron sucrose.
    Primary funding source: None.
    MeSH term(s) Aged ; Anaphylaxis/chemically induced ; Anaphylaxis/epidemiology ; Cohort Studies ; Dextrans ; Ferric Oxide, Saccharated/adverse effects ; Ferrosoferric Oxide ; Humans ; Iron/adverse effects ; Iron-Dextran Complex/adverse effects ; Medicare ; Retrospective Studies ; United States/epidemiology
    Chemical Substances Dextrans ; Iron-Dextran Complex (9004-66-4) ; Iron (E1UOL152H7) ; Ferric Oxide, Saccharated (FZ7NYF5N8L) ; Ferrosoferric Oxide (XM0M87F357)
    Language English
    Publishing date 2022-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M21-4009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.178/2: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Current WHO hemoglobin thresholds for altitude and misdiagnosis of anemia among Tibetan highlanders.

    Sarna, Kaylee / Brittenham, Gary M / Beall, Cynthia M

    American journal of hematology

    2020  Volume 95, Issue 6, Page(s) E134–E136

    MeSH term(s) Adult ; Altitude ; Anemia/blood ; Anemia/diagnosis ; Diagnostic Errors ; Female ; Hemoglobins/metabolism ; Humans ; Male ; Tibet
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Letter
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.25765
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: The Centers for Disease Control and Prevention does not recommend race-adjusted thresholds to define anemia.

    Jefferds, Maria Elena D / Addo, O Yaw / Scanlon, Kelley S / Cogswell, Mary E / Brittenham, Gary M / Mei, Zuguo

    The American journal of clinical nutrition

    2023  Volume 119, Issue 1, Page(s) 232–233

    MeSH term(s) Humans ; United States/epidemiology ; Anemia/prevention & control ; Hemoglobins/analysis ; Centers for Disease Control and Prevention, U.S.
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2023-11-27
    Publishing country United States
    Document type Letter
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1016/j.ajcnut.2023.08.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top