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  1. Article ; Online: The Bumpy Road for Noninvasive Ventilation in Acute Respiratory Distress Syndrome. Coming to an End?

    Hill, Nicholas S / Garpestad, Erik

    American journal of respiratory and critical care medicine

    2017  Volume 195, Issue 1, Page(s) 9–10

    Language English
    Publishing date 2017-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201610-2138ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
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  2. Article ; Online: Polypharmacy and Delirium in Critically Ill Older Adults: Recognition and Prevention.

    Garpestad, Erik / Devlin, John W

    Clinics in geriatric medicine

    2017  Volume 33, Issue 2, Page(s) 189–203

    Abstract: Among older adults, polypharmacy is a sequelae of admission to the intensive care unit and is associated with increased medication-associated adverse events, drug interactions, and health care costs. Delirium is prevalent in critically ill geriatric ... ...

    Abstract Among older adults, polypharmacy is a sequelae of admission to the intensive care unit and is associated with increased medication-associated adverse events, drug interactions, and health care costs. Delirium is prevalent in critically ill geriatric patients and medications remain an underappreciated modifiable risk for delirium in this setting. This article reviews the literature on polypharmacy and delirium, with a focus on highlighting the relationships between polypharmacy and delirium in critically ill, older adults. Discussed are clinician strategies on how to recognize and reduce medication-associated delirium and recommendations that help prevent polypharmacy when interventions to reduce the burden of delirium in this vulnerable population are being formulated.
    Language English
    Publishing date 2017-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1064151-8
    ISSN 1879-8853 ; 0749-0690
    ISSN (online) 1879-8853
    ISSN 0749-0690
    DOI 10.1016/j.cger.2017.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Low Tidal Volume Ventilation: Trust but Verify.

    Ghamloush, Maher A / Garpestad, Erik

    Respiratory care

    2015  Volume 60, Issue 12, Page(s) 1852–1853

    MeSH term(s) Humans ; Respiration ; Respiration, Artificial ; Respiratory Distress Syndrome, Adult ; Tidal Volume
    Language English
    Publishing date 2015-12
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.04530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Naloxegol to Prevent Constipation in ICU Adults Receiving Opioids: A Randomized Double-Blind Placebo-Controlled Pilot Trial.

    Duprey, Matthew S / Allison, Harmony / Garpestad, Erik / Riselli, Andrew M / Faugno, Anthony / Anketell, Eric / Devlin, John W

    Critical care research and practice

    2022  Volume 2022, Page(s) 7541378

    Abstract: Background: Constipation is frequent in critically ill adults receiving opioids. Naloxegol (N), a peripherally acting mu-receptor antagonist (PAMORA), may reduce constipation. The objective of this trial was to evaluate the efficacy and safety of N to ... ...

    Abstract Background: Constipation is frequent in critically ill adults receiving opioids. Naloxegol (N), a peripherally acting mu-receptor antagonist (PAMORA), may reduce constipation. The objective of this trial was to evaluate the efficacy and safety of N to prevent constipation in ICU adults receiving opioids.
    Results: Only 318 (20.6%) of the 1542 screened adults during the 1/17-10/19 enrolment period met all inclusion criteria. Of these, only 19/381 (4.9%) met all eligibility criteria. After 7 consent refusals, 12 patients were randomized. The study was stopped early due to enrolment futility. The N (
    Conclusions: Important recruitment challenges exist for ICU trials evaluating the use of PAMORAs for constipation prevention. Despite being underpowered, our results suggest time to first SBM with naloxegol, if different than P, may be small. The effect of naloxegol on abdominal pressure, SOFA, and the interaction between the two requires further research.
    Language English
    Publishing date 2022-03-20
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2573849-5
    ISSN 2090-1313 ; 2090-1305
    ISSN (online) 2090-1313
    ISSN 2090-1305
    DOI 10.1155/2022/7541378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Judicious Use of Noninvasive Ventilatory Modalities for Severe Pneumonia/ARDS.

    Hill, Nicholas S / Garpestad, Erik / Schumaker, Greg / Spoletini, Giulia

    Turkish journal of anaesthesiology and reanimation

    2018  Volume 46, Issue 1, Page(s) 3–4

    Language English
    Publishing date 2018-02-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 2667-677X
    ISSN 2667-677X
    DOI 10.5152/TJAR.2018.130202
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  6. Article ; Online: Noninvasive Ventilatory Support for Acute Hypercapnic Respiratory Failure.

    Hill, Nicholas S / Spoletini, Giulia / Schumaker, Gregory / Garpestad, Erik

    Respiratory care

    2019  Volume 64, Issue 6, Page(s) 647–657

    Abstract: Noninvasive ventilation is well established as the ventilatory modality of first choice to treat acute or acute-on-chronic hypercapnic respiratory failure in patients with COPD by improving dyspnea and gas exchange, avoiding the need for intubation, and ... ...

    Abstract Noninvasive ventilation is well established as the ventilatory modality of first choice to treat acute or acute-on-chronic hypercapnic respiratory failure in patients with COPD by improving dyspnea and gas exchange, avoiding the need for intubation, and reducing morbidity and mortality rates. Noninvasive ventilation also offers benefit for patients with COPD and with accompanying pneumonia or with hypercapnic respiratory failure in postextubation, postoperative, and do not intubate settings. Noninvasive ventilation, in addition, offers benefit in other forms of acute hypercapnic respiratory failure, including those caused by asthma, cystic fibrosis, and obesity hypoventilation. A newer form of noninvasive ventilatory assistance, high-flow nasal cannula, has emerged in recent years as a technique to not only oxygenate effectively but also to improve ventilatory efficiency and reduce the work of breathing in patients with severe COPD. Results of recent studies indicate that high-flow nasal cannula therapy can benefit some patients with acute hypercapnic respiratory failure, either instead of or in combination with noninvasive ventilation, but more study is needed.
    MeSH term(s) Humans ; Hypercapnia/physiopathology ; Hypercapnia/therapy ; Noninvasive Ventilation/methods ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/therapy ; Respiratory Insufficiency/physiopathology ; Respiratory Insufficiency/therapy ; Work of Breathing
    Language English
    Publishing date 2019-05-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.06931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Noninvasive Ventilation for Acute Hypoxemic Respiratory Failure/ARDS - is There a Role?

    Hill, Nicholas S / Garpestad, Erik / Schumaker, Greg / Spoletini, Giulia

    Turkish journal of anaesthesiology and reanimation

    2017  Volume 45, Issue 6, Page(s) 332–334

    Language English
    Publishing date 2017-12-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 2667-677X
    ISSN 2667-677X
    DOI 10.5152/TJAR.2017.24.11.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High-Flow Nasal Oxygen or Noninvasive Ventilation for Postextubation Hypoxemia: Flow vs Pressure?

    Spoletini, Giulia / Garpestad, Erik / Hill, Nicholas S

    JAMA

    2016  Volume 315, Issue 13, Page(s) 1340–1342

    MeSH term(s) Airway Extubation ; Digestive System Surgical Procedures/adverse effects ; Female ; Humans ; Hypoxia/therapy ; Intubation, Intratracheal/utilization ; Male ; Noninvasive Ventilation/statistics & numerical data ; Oxygen Inhalation Therapy/methods ; Oxygen Inhalation Therapy/statistics & numerical data ; Postoperative Complications/therapy ; Respiration, Artificial ; Respiratory Insufficiency/therapy
    Language English
    Publishing date 2016-04-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2016.2709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Corrigendum to "A survey of critical care nurses' practices and perceptions surrounding early intravenous antibiotic initiation during septic shock" [Intensive Crit. Care Nurs. 41 (2017) 90-97].

    Roberts, Russel J / Alhammad, Abdullah M / Crossley, Lindsay / Anketell, Eric / Wood, LeeAnn / Schumaker, Greg / Garpestad, Erik / Devlin, John W

    Intensive & critical care nursing

    2020  Volume 63, Page(s) 102997

    Language English
    Publishing date 2020-12-18
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2020.102997
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  10. Article ; Online: Deploying the Physician Workforce During a Respiratory Pandemic: The Experience of an Academic Teaching Hospital During the COVID-19 Pandemic.

    Roberts, Kari E / Kher, Sucharita / Garpestad, Erik / Mohanty, Sharanya / Davis, Michael / Kumar, Anupama / Chweich, Haval / Boucher, Helen W / Poutsiaka, Debra D / Weingart, Saul N / Freund, Karen M

    Quality management in health care

    2021  Volume 31, Issue 2, Page(s) 99–104

    MeSH term(s) COVID-19/epidemiology ; Hospitals, Teaching ; Humans ; Pandemics ; Physicians ; Workforce
    Language English
    Publishing date 2021-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1162319-6
    ISSN 1550-5154 ; 1063-8628
    ISSN (online) 1550-5154
    ISSN 1063-8628
    DOI 10.1097/QMH.0000000000000321
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