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Article: Multisystem Inflammatory Syndrome after Ad26.COV2.S vaccination.

Bova, Carlo / Vigna, Ernesto / Gentile, Massimo

2022 Volume 27, Page(s) e01411

Abstract: ... with Ad26. COV2. S vaccine (Johnson &Johnson/Janssen), a recombinant adenovirus serotype 26 vector encoding ...

Abstract	Background: The multisystem inflammatory syndrome (MIS) is a rare and sometime life-threatening post-infectious complication of coronavirus disease 2019 (Covid-19) in children and adults. To date, only a very few reports have associated such systemic reaction with SARS-CoV-2 vaccination. Case report: we describe a case that resembled MIS, in a 46-year-old White man, 12 days after vaccination with Ad26. COV2. S vaccine (Johnson &Johnson/Janssen), a recombinant adenovirus serotype 26 vector encoding the SARS-CoV-2 spike glycoprotein. The patient experienced high grade fever, cutaneous rash, severe weakness, pericardial effusion and raised inflammatory markers, which met the criteria for definition of MIS. The symptoms improved with steroidal therapy. Conclusions: Our case suggests that MIS could occur after SARS-CoV-2 vaccination.
Language	English
Publishing date	2022-01-21
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2745454-X
ISSN	2214-2509
ISSN	2214-2509
DOI	10.1016/j.idcr.2022.e01411
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Episodic Angioedema with Hypereosinophilia (Gleich’s Syndrome)

Ilaria Mormile / Angelica Petraroli / Stefania Loffredo / Francesca Wanda Rossi / Mauro Mormile / Andrea Del Mastro / Giuseppe Spadaro / Amato de Paulis / Maria Bova

Journal of Clinical Medicine, Vol 10, Iss 1442, p

A Case Report and Extensive Review of the Literature

2021 Volume 1442

Abstract: Episodic angioedema with eosinophilia (EAE) (Gleich’s syndrome) is a rare disease characterized ...

Abstract	Episodic angioedema with eosinophilia (EAE) (Gleich’s syndrome) is a rare disease characterized by hypereosinophilia (up to 95 × 10 9 cells/L), recurrent episodes of angioedema, urticaria, weight gain, and fever, that occur at periodical intervals (usually every 3–4 weeks). The exact etiology of EAE is still unclear, but both eosinophils and abnormalities of cytokines homeostasis seem to play a pivotal role in the pathogenesis of the disease. In particular, the cyclic elevation of serum interleukin-5 before the increase in eosinophil count has been reported. Herein, we performed a broad literature review and report the case of a thirty-two-year-old woman with a two-year history of cyclic angioedema attacks, urticaria, periodic weight gain, and severe hypereosinophilia, diagnosed with EAE and treated with oral corticosteroids. Describing the most relevant clinical features of EAE reported so far in the literature, we aim to provide physicians with some useful tools to help them deal with this disease. In addition, we aim to raise awareness about this rare condition in which approved diagnostic classification criteria are currently missing.
Keywords	angioedema ; acquired angioedema ; episodic angioedema with eosinophilia ; Gleich’s syndrome ; hypereosinophilia ; interleukin-5 ; Medicine ; R
Subject code	610
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prevalence and treatment of neuropathic pain diagnoses among U.S. nursing home residents.

Mbrah, Attah K / Nunes, Anthony P / Hume, Anne L / Zhao, Danni / Jesdale, Bill M / Bova, Carol / Lapane, Kate L

Pain

2021 Volume 163, Issue 7, Page(s) 1370–1377

Abstract: Abstract: Neuropathic pain is a common condition experienced by older adults. Prevalence estimates of neuropathic pain and descriptive data of pharmacologic management among nursing home residents are unavailable. We estimated the prevalence of ... ...

Abstract	Abstract: Neuropathic pain is a common condition experienced by older adults. Prevalence estimates of neuropathic pain and descriptive data of pharmacologic management among nursing home residents are unavailable. We estimated the prevalence of neuropathic pain diagnoses and described the use of pain medications among nursing home residents with possible neuropathic pain. Using the Minimum Data Set 3.0 linked to Medicare claims for residents living in a nursing home on November 30, 2016, we included 473,815 residents. ICD-10 codes were used to identify neuropathic pain diagnoses. Identification of prescription analgesics/adjuvants was based on claims for the supply of medications that overlapped with the index date over a 3-month look-back period. The prevalence of neuropathic pain was 14.6%. Among those with neuropathic pain, 19.7% had diabetic neuropathy, 27.3% had back and neck pain with neuropathic involvement, and 25.1% had hereditary or idiopathic neuropathy. Among residents with neuropathic pain, 49.9% received anticonvulsants, 28.6% received antidepressants, 19.0% received opioids, and 28.2% had no claims for analgesics or adjuvants. Resident characteristics associated with lack of medications included advanced age, dependency in activities of daily living, cognitive impairment, and diagnoses of comorbid conditions. A diagnosis of neuropathic pain is common among nursing home residents, yet many lack pharmacologic treatment for their pain. Future epidemiologic studies can help develop a more standard approach to identifying and managing neuropathic pain among nursing home residents.
MeSH term(s)	Activities of Daily Living ; Aged ; Analgesics/therapeutic use ; Humans ; Medicare ; Neuralgia/diagnosis ; Neuralgia/drug therapy ; Neuralgia/epidemiology ; Nursing Homes ; Prevalence ; United States/epidemiology
Chemical Substances	Analgesics
Language	English
Publishing date	2021-10-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	193153-2
ISSN	1872-6623 ; 0304-3959
ISSN (online)	1872-6623
ISSN	0304-3959
DOI	10.1097/j.pain.0000000000002525
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Zs.A 1158: Show issues

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Article: Khirurgicheskoe lechenie bol'nogo s travmaticheskim razryvom dugi aorty i pozdneĭ perforatsieĭ pishchevoda.

Shlomin, V V / Nokhrin, A V / Orzheshkovskaia, I E / Bova, V I / Nefedov, A V / Mikhaĭlov, I V / Bondarenko, P B / Puzdriak, P D / Dmitrievskaia, N O

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery

2020 Volume 26, Issue 2, Page(s) 175–182

Abstract: Described herein is a clinical case report regarding a patient presenting with traumatic rupture of the aortic isthmus with the development of a pseudoaneurysm occupying virtually the entire posterior mediastinum and measuring 20?10 cm in size. He was ... ...

Title translation	Surgical treatment of a patient with traumatic rupture of the aortic arch and late oesophageal perforation.
Abstract	Described herein is a clinical case report regarding a patient presenting with traumatic rupture of the aortic isthmus with the development of a pseudoaneurysm occupying virtually the entire posterior mediastinum and measuring 20?10 cm in size. He was immediately treated as an emergency to undergo prosthetic reconstruction of the portion of the aortic arch and descending thoracic aorta by means of temporary bypass grafting with a synthetic graft in order to protect the visceral organs. The postoperative period was complicated by oesophageal perforation with the formation of an oesophago-paraprosthetic fistula, infection of the vascular graft, accompanied by the development of pleural empyema and mediastinitis. A second operative procedure was performed, consisting of subclavian-iliac bypass grafting on the right with a polytetrafluoroethylene graft measuring 20 mm in diameter, exclusion of the intrathoracic portion of the oesophagus, creation of a gastro- and oesophagostoma, retrieval of the vascular graft followed by suturing of the aorta, pleurectomy, decortication of the lung, and removal of the empyemic sac on the left. There was no evidence of ischaemia of the spinal cord or visceral arteries. One month postoperatively, he underwent a traumatological stage and 4 months thereafter plasty of the oesophagus with an isoperistaltic gastric pedicle, extirpation of the thoracic portion of the oesophagus, to be later on followed by closure of the oesophagostoma. The patient experienced no difficulties either while walking or during other physical activities, with the ankle-brachial index amounting to 0.9. With time, he developed difficult-to-correct pulmonary hypertension. Unfortunately, the patient eventually died of acute cardiopulmonary insufficiency 9 years after right-sided extra-anatomical subclavian-iliac bypass grafting.
MeSH term(s)	Aneurysm, False ; Aorta ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic ; Aortic Rupture/diagnosis ; Esophageal Perforation/diagnosis ; Esophageal Perforation/etiology ; Esophageal Perforation/surgery ; Humans ; Male
Language	Russian
Publishing date	2020-06-29
Publishing country	Russia (Federation)
Document type	Case Reports ; Journal Article
ZDB-ID	2186202-3
ISSN	1027-6661
ISSN	1027-6661
DOI	10.33529/ANGIO2020219
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Zs.A 6111: Show issues

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Article: Prevalence of Twiddler’s Syndrome as a Cause of Deep Brain Stimulation Hardware Failure

Burdick, Adam P. / Okun, Michael S. / Haq, Ihtsham U. / Ward, Herbert E. / Bova, Frank / Jacobson, Charles E. / Bowers, Dawn / Zeilman, Pam / Foote, Kelly D.

Stereotactic and Functional Neurosurgery

2010 Volume 88, Issue 6, Page(s) 353–359

Abstract: ... which resulted from implantable pulse generator mobility, a phenomenon referred to as twiddler’s syndrome ... there were 17 hardware malfunctions. Three of them were due to twiddler’s syndrome, representing 1.3 ... generator within the chest pocket resolved the issue. Twiddler’s syndrome in the population of movement ...

Institution	Departments of Neurosurgery Neurology Psychiatry and Clinical and Health Psychology, University of Florida, Gainesville, Fla., and Wake Forest University Department of Neurology, Winston Salem, N.C., USA
Abstract	We reviewed our deep brain stimulation patient database to describe hardware complications which resulted from implantable pulse generator mobility, a phenomenon referred to as twiddler’s syndrome. A prospectively collected database of adverse events for all patients operated on at the University of Florida was queried searching for hardware malfunctions. Of 362 total leads implanted in 226 patients since 2002, there were 17 hardware malfunctions. Three of them were due to twiddler’s syndrome, representing 1.3% of patients (3 of 226 patients) and 1.4% of leads (5 of 362 leads). The subjects had characteristic presentations including re-emergence of symptoms, pain along the path of the hardware, abnormal impedances/current drain and radiographic signs of twisting/fracture. In all cases securing the implantable pulse generator within the chest pocket resolved the issue. Twiddler’s syndrome in the population of movement disorder patients treated with deep brain stimulation is an uncommon but important adverse event. It possesses a characteristic presentation and with appropriate diagnostic evaluation it is treatable and future occurrences are preventable.
Keywords	Twiddler’s syndrome, complication ; Deep brain stimulation ; Adverse event
Language	English
Publishing date	2010-09-22
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Clinical Study
ZDB-ID	645069-6
ISSN	1423-0372 ; 1011-6125
ISSN (online)	1423-0372
ISSN	1011-6125
DOI	10.1159/000319039
Database	Karger publisher's database

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Article: Evidence-Based Storytelling for a Strategic Roadmap to Promote Cancer Prevention via Adolescent HPV Vaccination in Northern New England.

Dugan, Matthew / Stein, Gary S / Carney, Jan Kirk / Clifford-Bova, Sheila

Critical reviews in eukaryotic gene expression

2024 Volume 34, Issue 4, Page(s) 69–102

Abstract: Vaccination rates for the human papillomavirus (HPV) among rural youth in northern New England lag those of more urbanized areas. Reasons include a lack of available medical offices, time constraints, perceptions of vaccines and HPV, and, to a smaller ... ...

Abstract	Vaccination rates for the human papillomavirus (HPV) among rural youth in northern New England lag those of more urbanized areas. Reasons include a lack of available medical offices, time constraints, perceptions of vaccines and HPV, and, to a smaller degree, delays caused by the COVID-19 pandemic. We have a responsibility to increase vaccinations in these communities. To do so, vaccination experts recommend addressing the three C's of vaccination hesitation: confidence, complacency, and convenience. With this framework as our foundation, in this article we detail a plan to address these important elements, and we add several more C's: clinics, communication, collaboration, community, capacity, and commitment to the list as we discuss the essential pieces-human, infrastructural, and perceptual-needed to create and promote successful, community-supported, school-based HPV vaccination clinics to serve youths aged nine to 18. We then integrate research and storytelling science into an innovative Persuasion Playbook, a guide for local opinion leaders to use in creating evidence-based, pro-vaccine messages on the community level to promote the clinics via evidence-based, pro-vaccination messages.
MeSH term(s)	Humans ; Adolescent ; Papillomavirus Infections/epidemiology ; Pandemics ; Neoplasms ; Vaccination ; Communication ; New England ; Papillomavirus Vaccines
Chemical Substances	Papillomavirus Vaccines
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1071345-1
ISSN	1045-4403
ISSN	1045-4403
DOI	10.1615/CritRevEukaryotGeneExpr.2024052382
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Zs.A 3226: Show issues

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Article: Clinical and Aberrometric Evaluation of a New Monofocal IOL with Intermediate Vision Improvement.

Bova, Alessandro / Vita, Stefano

Journal of ophthalmology

2022 Volume 2022, Page(s) 4119698

Abstract: Purpose: The aim of the study was to evaluate the visual outcomes, aberrometric results, and subjective and objective optical qualities 12 months after implantation of a new monofocal intraocular lens (Physiol IsoPure 1.2.3) in comparison with a ... ...

Abstract	Purpose: The aim of the study was to evaluate the visual outcomes, aberrometric results, and subjective and objective optical qualities 12 months after implantation of a new monofocal intraocular lens (Physiol IsoPure 1.2.3) in comparison with a standard monofocal intraocular lens (Tecnis PCB00). Materials and methods: Cataract patients without ocular comorbidities had bilateral implantation of the IsoPure IOL or the PCB00 IOL. One month after eye surgery, the visual acuity and monocular defocus curve were assessed. Twelve months after surgery, the visual acuity, binocular defocus curve, contrast sensitivity, and subjective/objective optical quality were assessed. Furthermore, wavefront analysis was performed. The primary endpoint was the best distance correct/uncorrected visual acuity at intermediate and far distances. The secondary endpoint was an aberration evaluation of the IOLs and contrast sensitivity. Results: The study comprised a total of 42 patients (84 eyes). Monocular and binocular uncorrected and corrected distance were similar between groups, and uncorrected intermediate visual acuity was significantly higher in the IsoPure group. There was no difference in contrast sensitivity and subjective and objective optical qualities. The optical aberrations at 3.0 and 5.0 mm aperture diameters were similar in both groups. Conclusion: The IsoPure IOL, based on greater depth of focus than the aspheric monofocal IOL, may offer a good option for the distance and intermediate vision without increasing optical aberrations and any photic phenomena.
Language	English
Publishing date	2022-07-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2546525-9
ISSN	2090-0058 ; 2090-004X
ISSN (online)	2090-0058
ISSN	2090-004X
DOI	10.1155/2022/4119698
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Article ; Online: Etiopathogenesis and Therapy of Epithelial Ingrowth after Descemet’s Stripping Automated Endothelial Keratoplasty

Francesco Semeraro / Attilio Di Salvatore / Alessandro Bova / Eliana Forbice

BioMed Research International, Vol

2014 Volume 2014

Abstract: Descemet’s stripping endothelial keratoplasty is an emerging technique finalized to treat ...

Abstract	Descemet’s stripping endothelial keratoplasty is an emerging technique finalized to treat endothelial dysfunction replacing only the pathological portion of cornea. The advent of any new technique puts us in front of new complications. The epithelial ingrowth is a well-known complication already studied in case of ocular trauma and more recently in refractive surgery. This job analyzed the potential etiopathogenesis of epithelial ingrowth after DSAEK, reviewing the cases described in literature, and suggests the potential therapy.
Keywords	Medicine ; R
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Vrodeno laringomukotsele - opisanie na edin sluchai s letalen krai.

Vasilev, I / G'l'bova, M / Velev, V / Buzalov, S / Todorova, M

Akusherstvo i ginekologiia

2000 Volume 40, Issue 4, Page(s) 48–49

Abstract: The authors describe a case of a newborn baby with inborn laryngomucocaele, living 14 days after birth. The newborn baby was looked after with artifical lentilation. Because of the inability of self breathing the baby underwent tracheostomia. The autopsy ...

Title translation	Inborn laryngeal cysts - description of a case with fatal outcome.
Abstract	The authors describe a case of a newborn baby with inborn laryngomucocaele, living 14 days after birth. The newborn baby was looked after with artifical lentilation. Because of the inability of self breathing the baby underwent tracheostomia. The autopsy revealed the presence of laryngomucocaele.
MeSH term(s)	Adult ; Fatal Outcome ; Female ; Humans ; Infant, Newborn ; Laryngeal Diseases/congenital ; Laryngeal Diseases/pathology ; Male ; Mucocele/congenital ; Mucocele/pathology ; Pregnancy
Language	Bulgarian
Publishing date	2000
Publishing country	Bulgaria
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	137491-6
ISSN	0324-0959 ; 0516-365X ; 0204-6954
ISSN	0324-0959 ; 0516-365X ; 0204-6954
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Article ; Online: Alien hand syndrome-like functional seizures in a patient with right temporo-parietal damage and neurocognitive disorder: a case report.

Mammì, Anna / Bova, Valentina / Ferlazzo, Edoardo / Pascarella, Angelo / Gasparini, Sara

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2024

Language	English
Publishing date	2024-03-20
Publishing country	Italy
Document type	Letter
ZDB-ID	2016546-8
ISSN	1590-3478 ; 1590-1874
ISSN (online)	1590-3478
ISSN	1590-1874
DOI	10.1007/s10072-024-07473-0
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