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  1. Article ; Online: Sedentary behaviour as a lifestyle risk factor in public health - Evidence of white-collar and blue-collar workers from Poland.

    Biernat, Elżbieta / Piątkowska, Monika

    Annals of agricultural and environmental medicine : AAEM

    2023  Volume 30, Issue 4, Page(s) 743–748

    Abstract: Introduction and objective: Relief from routine physical tasks leads to increasingly sedentary behaviour (SB) - a risk factor for non-communicable chronic diseases. It is necessary to gather interdisciplinary knowledge about the possibilities of its ... ...

    Abstract Introduction and objective: Relief from routine physical tasks leads to increasingly sedentary behaviour (SB) - a risk factor for non-communicable chronic diseases. It is necessary to gather interdisciplinary knowledge about the possibilities of its reduction. The aim of the study is to analyse SB and its conditions among Polish white-collar and blue-collar workers.
    Material and methods: The study is based on data retrieved from a large-scale survey used to collect information on the physical activity of Polish society. The data were gathered on a representative sample of Poles at working age ≤69 years old in 2017 (n=2,131). The Polish long version of the International Physical Activity Questionnaire (IPAQ-LF) was used. Statistical inference was based on non-parametric (U-Mann Whitney and Kruskal-Wallis) tests.
    Results: The total average sitting time of the respondents was 1,958.5 min./week. White-collar workers are more likely (p 7.5 h/day (20.2% vs 9%), and blue-collar - ≤4.5 h/day (56.5% vs 42.1%). On a weekday, white-collar workers are sitting significantly longer. The bigger the place of residence, the longer the time sitting in both groups (p=0.000). The time of sitting on a non-working day does not differ among white-collar (221.4 min./day) and blue-collar workers (230.4 min./day). White-collar workers sit longer in vehicles (p <0.0001): 482.4 vs blue-collar workers 326.8 min./week.
    Conclusions: The results suggest a change in Polish recommendations regarding the SB. Blue-collar and white-collar workers need support from the State policy in this matter and need guidance from pro-health programmes. It is necessary to intensify coherent, interdisciplinary and intersectoral activities aimed at creating environments that effectively counteract SB in the place of work and residence, especially in the larger agglomerations.
    MeSH term(s) Humans ; Aged ; Sedentary Behavior ; Poland ; Public Health ; Life Style ; Risk Factors ; Occupations
    Language English
    Publishing date 2023-05-29
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1215115-4
    ISSN 1898-2263 ; 1232-1966
    ISSN (online) 1898-2263
    ISSN 1232-1966
    DOI 10.26444/aaem/165980
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  2. Article: The Synthesis of Hydroxyapatite by Hydrothermal Process with Calcium Lactate Pentahydrate: The Effect of Reagent Concentrations, pH, Temperature, and Pressure.

    Szterner, Piotr / Biernat, Monika

    Bioinorganic chemistry and applications

    2022  Volume 2022, Page(s) 3481677

    Abstract: Hydroxyapatite and other calcium phosphates in the form of whiskers are lately widely considered as fillers for biocomposites due to their special biological and reinforcing properties. Depending on the method of synthesis, apatite whiskers of various ... ...

    Abstract Hydroxyapatite and other calcium phosphates in the form of whiskers are lately widely considered as fillers for biocomposites due to their special biological and reinforcing properties. Depending on the method of synthesis, apatite whiskers of various sizes and phase composition can be obtained. In our work, hydroxyapatite (HAp) whiskers were successfully prepared in reaction between calcium lactate pentahydrate and orthophosphoric acid. The advantage of the proposed technique is the simple but precise control of the HAp crystal morphology and high product purity which is necessary for biomedical applications. The effect of reagent concentrations, pH, reaction temperature, and pressure on HAp whiskers' morphology and composition was investigated. In the result, we obtained hydroxyapatite of different morphology such as whiskers, hexagonal rods, and nanorods. The products were characterized by SEM, XRD, and FTIR. In this work, the synthesis of HAp whiskers by direct decomposition of calcium lactate pentahydrate chelates under hydrothermal conditions was showed for the first time.
    Language English
    Publishing date 2022-03-25
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2213020-2
    ISSN 1687-479X ; 1565-3633
    ISSN (online) 1687-479X
    ISSN 1565-3633
    DOI 10.1155/2022/3481677
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  3. Article ; Online: Chitosan and Sodium Hyaluronate Hydrogels Supplemented with Bioglass for Bone Tissue Engineering.

    Ciołek, Lidia / Zaczyńska, Ewa / Krok-Borkowicz, Małgorzata / Biernat, Monika / Pamuła, Elżbieta

    Gels (Basel, Switzerland)

    2024  Volume 10, Issue 2

    Abstract: The aim of the study was to produce biocomposites based on chitosan and sodium hyaluronate hydrogels supplemented with bioglasses obtained under different conditions (temperature, time) and to perform an in vitro evaluation of their cytocompatibility ... ...

    Abstract The aim of the study was to produce biocomposites based on chitosan and sodium hyaluronate hydrogels supplemented with bioglasses obtained under different conditions (temperature, time) and to perform an in vitro evaluation of their cytocompatibility using both indirect and direct methods. Furthermore, the release of ions from the composites and the microstructure of the biocomposites before and after incubation in simulated body fluid were assessed. Tests on extracts from bioglasses and hydrogel biocomposites were performed on A549 epithelial cells, while MG63 osteoblast-like cells were tested in direct contact with the developed biomaterials. The immune response induced by the biomaterials was also evaluated. The experiments were carried out on both unstimulated and lipopolysaccharide (LPS) endotoxin-stimulated human peripheral blood cells in the presence of extracts of the biocomposites and their components. Extracts of the materials produced do not exhibit toxic effects on A549 cells, and do not increase the production of proinflammatory cytokines tumour necrosis factor alpha (TNF-α) and interleukin (IL-6) by blood cells in vitro. In direct contact with MG63 osteoblast-like cells, biocomposites containing the reference bioglass and those containing SrO are more cytocompatible than biocomposites with ZnO-doped bioglass. Using two testing approaches, the effects both of the potentially toxic agents released and of the surface of the tested materials on the cell condition were assessed. The results pave the way for the development of highly porous hydrogel-bioglass composite scaffolds for bone tissue engineering.
    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2813982-3
    ISSN 2310-2861 ; 2310-2861
    ISSN (online) 2310-2861
    ISSN 2310-2861
    DOI 10.3390/gels10020128
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  4. Article ; Online: Analgesic Peptides: From Natural Diversity to Rational Design.

    Gach-Janczak, Katarzyna / Biernat, Monika / Kuczer, Mariola / Adamska-Bartłomiejczyk, Anna / Kluczyk, Alicja

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 7

    Abstract: Pain affects one-third of the global population and is a significant public health issue. The use of opioid drugs, which are the strongest painkillers, is associated with several side effects, such as tolerance, addiction, overdose, and even death. An ... ...

    Abstract Pain affects one-third of the global population and is a significant public health issue. The use of opioid drugs, which are the strongest painkillers, is associated with several side effects, such as tolerance, addiction, overdose, and even death. An increasing demand for novel, safer analgesic agents is a driving force for exploring natural sources of bioactive peptides with antinociceptive activity. Since the G protein-coupled receptors (GPCRs) play a crucial role in pain modulation, the discovery of new peptide ligands for GPCRs is a significant challenge for novel drug development. The aim of this review is to present peptides of human and animal origin with antinociceptive potential and to show the possibilities of their modification, as well as the design of novel structures. The study presents the current knowledge on structure-activity relationship in the design of peptide-based biomimetic compounds, the modification strategies directed at increasing the antinociceptive activity, and improvement of metabolic stability and pharmacodynamic profile. The procedures employed in prolonged drug delivery of emerging compounds are also discussed. The work summarizes the conditions leading to the development of potential morphine replacements.
    MeSH term(s) Animals ; Humans ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Peptides/pharmacology ; Morphine ; Pain ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use
    Chemical Substances Analgesics ; Peptides ; Morphine (76I7G6D29C) ; Analgesics, Opioid
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29071544
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  5. Article ; Online: Is the Prevalence of Low Physical Activity among Teachers Associated with Depression, Anxiety, and Stress?

    Biernat, Elżbieta / Piątkowska, Monika / Rozpara, Michał

    International journal of environmental research and public health

    2022  Volume 19, Issue 14

    Abstract: The aim of this study was to analyze the levels of stress, depression, and anxiety among Polish secondary school teachers and their association with selected psychosocial, sociodemographic, and lifestyle factors. A cross-sectional study was conducted ... ...

    Abstract The aim of this study was to analyze the levels of stress, depression, and anxiety among Polish secondary school teachers and their association with selected psychosocial, sociodemographic, and lifestyle factors. A cross-sectional study was conducted among 116 Polish teachers in 2019, using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), the Depression and Anxiety Stress Scale (DASS-21), and author questionnaire including psychosocial factors specific to the respondents' work environment. The prevalence of moderately to extremely severe levels of depression, anxiety, and symptoms of stress in teachers was 18.1%, 22.4%, and 51.7%, respectively. Among respondents with moderate or high physical activity level (PAL), normal or mild levels of depression (OR = 3.62; CI [1.31-10.03]), anxiety (OR = 2.61; CI [1.01-6.73]), and stress (OR = 2.79; CI [1.16-6.69]) were more common. The level of individual symptoms of mental disorders was higher than indicated by previous Polish reports. Given that teachers' low PAL is significantly related to their moderately to extremely severe levels of stress, depression, and anxiety, we suggest running leisure-time physical activity (LTPA) enhancement programs and supporting the leadership of school management and the higher-education system in this regard.
    MeSH term(s) Anxiety/psychology ; Cross-Sectional Studies ; Depression/psychology ; Exercise ; Humans ; Prevalence ; Surveys and Questionnaires
    Language English
    Publishing date 2022-07-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19148868
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  6. Article ; Online: Sociodemographic Determinants of Physical Inactivity of People Aged 60 Years and Older: A Cross-Sectional Study in Poland.

    Biernat, Elżbieta / Piątkowska, Monika

    BioMed research international

    2020  Volume 2020, Page(s) 7469021

    Abstract: Purpose: The aim of the study was to evaluate general physical activity (PA) level on the basis of leisure time and transportation physical activity (LTPA and TPA), assess the percentage of persons not meeting PA recommendations by the World Health ... ...

    Abstract Purpose: The aim of the study was to evaluate general physical activity (PA) level on the basis of leisure time and transportation physical activity (LTPA and TPA), assess the percentage of persons not meeting PA recommendations by the World Health Organisation (WHO), and evaluate the relationship between selected sociodemographic factors and physical inactivity.
    Methods: The paper is based on data (
    Results: The total average energy expenditure amounted to 1879.5 ± 2352.5 MET-min/week, including LTPA (938.5 ± 1491.9 MET-min/week) and TPA (944.8 ± 1322.4 MET-min/week). Over the course of the last two years of the study, the average value of MET-min/week increased significantly (
    Conclusions: The target for future interventions should be people aged 60+ living in villages and small towns (especially those with primary education). It is necessary to undertake educational and motivational programmes promoting PA. It is essential to develop detailed recommendations and to create a friendly and supportive environment.
    MeSH term(s) Aged ; Cross-Sectional Studies ; Exercise ; Female ; Humans ; Male ; Middle Aged ; Poland/epidemiology ; Residence Characteristics/statistics & numerical data ; Sedentary Behavior ; Socioeconomic Factors ; Surveys and Questionnaires
    Language English
    Publishing date 2020-12-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2020/7469021
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  7. Article ; Online: Calcination and ion substitution improve physicochemical and biological properties of nanohydroxyapatite for bone tissue engineering applications.

    Kurzyk, Agata / Szwed-Georgiou, Aleksandra / Pagacz, Joanna / Antosik, Agnieszka / Tymowicz-Grzyb, Paulina / Gerle, Anna / Szterner, Piotr / Włodarczyk, Marcin / Płociński, Przemysław / Urbaniak, Mateusz M / Rudnicka, Karolina / Biernat, Monika

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 15384

    Abstract: Nanohydroxyapatite (nanoHAP) is widely used in bone regeneration, but there is a need to enhance its properties to provide stimuli for cell commitment and osteoconduction. This study examines the effect of calcination at 1200 °C on the physicochemical ... ...

    Abstract Nanohydroxyapatite (nanoHAP) is widely used in bone regeneration, but there is a need to enhance its properties to provide stimuli for cell commitment and osteoconduction. This study examines the effect of calcination at 1200 °C on the physicochemical and biological properties of nanoHAP doped with magnesium (Mg
    MeSH term(s) Tissue Engineering ; Bone and Bones ; Osteoblasts ; Apatites ; Bone Regeneration
    Chemical Substances Apatites
    Language English
    Publishing date 2023-09-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-42271-2
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  8. Article: Quantitative and Qualitative Airborne Mycobiota Surveillance in High-Risk Hospital Environment.

    Górzyńska, Aleksandra / Grzech, Aneta / Mierzwiak, Paulina / Ussowicz, Marek / Biernat, Monika / Nawrot, Urszula

    Microorganisms

    2023  Volume 11, Issue 4

    Abstract: 1) Background: The primary aim of the presented study was to assess the prevalence of fungi in the indoor air of selected hospital wards, and the additional goal was to evaluate the susceptibility of cultured isolates ... ...

    Abstract (1) Background: The primary aim of the presented study was to assess the prevalence of fungi in the indoor air of selected hospital wards, and the additional goal was to evaluate the susceptibility of cultured isolates of
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11041031
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  9. Article ; Online: Bioactive Glasses Enriched with Strontium or Zinc with Different Degrees of Structural Order as Components of Chitosan-Based Composite Scaffolds for Bone Tissue Engineering.

    Ciołek, Lidia / Krok-Borkowicz, Małgorzata / Gąsiński, Arkadiusz / Biernat, Monika / Antosik, Agnieszka / Pamuła, Elżbieta

    Polymers

    2023  Volume 15, Issue 19

    Abstract: The development of innovative biomaterials with improved integration with bone tissue and stimulating regeneration processes is necessary. Here, we evaluate the usefulness of bioactive glasses from the ... ...

    Abstract The development of innovative biomaterials with improved integration with bone tissue and stimulating regeneration processes is necessary. Here, we evaluate the usefulness of bioactive glasses from the SiO
    Language English
    Publishing date 2023-10-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15193994
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  10. Article ; Online: Leisure-Time Physical Activity Participation Trends 2014-2018: A Cross-Sectional Study in Poland.

    Biernat, Elżbieta / Piątkowska, Monika

    International journal of environmental research and public health

    2019  Volume 17, Issue 1

    Abstract: Objective, the aim is an analysis of sociodemographic factors that had an essential relation with undertaking leisure-time physical activity-LTPA (with particular emphasis on World Health Organization (WHO) health recommendations) by adult Poles from a ... ...

    Abstract Objective, the aim is an analysis of sociodemographic factors that had an essential relation with undertaking leisure-time physical activity-LTPA (with particular emphasis on World Health Organization (WHO) health recommendations) by adult Poles from a time-trend perspective. Methods, the paper is based on data retrieved from five large-scale surveys carried out on the representative samples of Poles aged 15-69 in 2014-2018 (
    MeSH term(s) Adolescent ; Adult ; Aged ; Community Participation/statistics & numerical data ; Cross-Sectional Studies ; Exercise/physiology ; Female ; Health Promotion ; Humans ; Leisure Activities/psychology ; Male ; Middle Aged ; Poland/epidemiology ; World Health Organization ; Young Adult
    Language English
    Publishing date 2019-12-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17010208
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