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  1. Book ; Online: Safety of COVID-19 vaccines in pregnancy

    Sadarangani, Manish / Bettinger, Julie A. / Cox, Rebecca J. / Cornely, Oliver Andreas

    VACCELERATE Webinar OCTOBER 25 2022

    2022  

    Abstract: This study took place in November 2021 and aimed to determine the frequency and nature of significant health events among pregnant females after COVID-19 vaccination, compared with unvaccinated pregnant controls and vaccinated non-pregnant individuals. ... ...

    Title variant Safety of COVID-19 vaccines in pregnancy : a Canadian National Vaccine Safety (CANVAS) network cohort study
    Institution VACCELERATE
    Author's details VACCELERATE ; presenter: Manish Sadarangani, Julie A. Bettinger ; moderator: Rebecca J. Cox ; organizor: VACCELERATE (Coordinator: Prof. Oliver A. Cornely)
    Abstract This study took place in November 2021 and aimed to determine the frequency and nature of significant health events among pregnant females after COVID-19 vaccination, compared with unvaccinated pregnant controls and vaccinated non-pregnant individuals. The working group set up an observational cohort study, set in seven Canadian provinces and territories. More than 1 million pregnant and non-pregnant females aged 15-49 years were enrolled as study participants. Data were collected primarily by self-reported survey after both vaccine doses, with telephone follow-up for those reporting any medically attended event. In this webinar, the results of the study will be presented, which give answer to the question if COVID-19 mRNA vaccines have a good safety profile in pregnancy and can be recommended. The speakers will also introduce the Canadian Vaccine Safety Network (CANVAS), which in addition to monitoring the seasonal influenza vaccine safety, monitors vaccine safety for other and new vaccines, and provides a platform for vaccine acceptability studies.
    Keywords COVID-19
    Subject Coronavirus-Krankheit-2019 ; Corona virus disease 2019 ; Coronavirus disease 2019 ; 2019-nCoV acute respiratory disease ; Wuhan pneumonia ; COVID-19-Infektion ; Coronavirus-SARS-CoV-2-Infektion ; SARS-CoV-2-Infektion
    Subject code 610
    Language English
    Size 1 Online-Ressource (1 Videodatei, Lauflänge: 00:56:34)
    Publisher VACCELERATE
    Publishing place Cologne
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT021575667
    DOI 10.4126/FRL01-006438188
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  2. Article ; Online: Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection.

    Zhou, Fan / Vahokoski, Juha / Langeland, Nina / Cox, Rebecca J

    NPJ vaccines

    2024  Volume 9, Issue 1, Page(s) 37

    Abstract: The endemic human coronaviruses (HCoVs) circulate worldwide yet remain understudied and unmitigated. The observation of elevated levels of HCoV reactive antibodies in COVID-19 patients highlights the urgent necessity of better understanding of HCoV ... ...

    Abstract The endemic human coronaviruses (HCoVs) circulate worldwide yet remain understudied and unmitigated. The observation of elevated levels of HCoV reactive antibodies in COVID-19 patients highlights the urgent necessity of better understanding of HCoV specific immunity. Here, we characterized in-depth the de novo SARS-CoV-2 specific antibody responses and the boosting of HCoV-reactive antibodies after SARS-CoV-2 vaccination or infection in individuals up to 98 years old. All the vaccinees were home-dwelling with no documented SARS-CoV-2 infection before receiving the COVID-19 mRNA vaccine (BNT162b2). The first two vaccine doses elicited potent SARS-CoV-2 spike binding antibodies in individuals up to 80 years. The third dose largely boosted the previously low S2 domain binding and neutralizing antibodies in elderly 80-90 years old, but less so in those above 90 years. The endemic betacoronavirus (HKU1 and OC43) reactive antibodies were boosted in all vaccinees, although to a lesser extent in those above 80 years old. COVID-19 patients had potent elevation of alpha- and betacoronavirus (229E, NL63, HKU1 and OC43) reactive antibodies. In both patients and vaccinees, S2 domain specific antibody increases correlated with SARS-CoV-2 neutralizing and HCoV-reactive antibody responses in all ages, indicating S2 domain as a candidate for future universal coronavirus vaccine design.
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ISSN 2059-0105
    ISSN (online) 2059-0105
    DOI 10.1038/s41541-024-00817-z
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  3. Article ; Online: Immunomodulatory effects of fucoidan in recreationally active adult males undertaking 3-weeks of intensified training.

    Cox, Amanda J / Speer, Hollie / Radcliffe, Ceridwen R / Masocha, Kathleen / Ramsey, Rebecca / West, Nicholas P / Pyne, David B

    Journal of sports sciences

    2024  Volume 41, Issue 20, Page(s) 1875–1882

    Abstract: The aim of the current study was to determine whether daily fucoidan supplementation ( ...

    Abstract The aim of the current study was to determine whether daily fucoidan supplementation (
    MeSH term(s) Adult ; Male ; Humans ; Muramidase ; Lactoferrin ; Immunoglobulin A ; Biomarkers ; Saliva ; Edible Seaweeds ; Polysaccharides ; Undaria
    Chemical Substances fucoidan (9072-19-9) ; Muramidase (EC 3.2.1.17) ; Lactoferrin (EC 3.4.21.-) ; Immunoglobulin A ; Biomarkers ; Polysaccharides
    Language English
    Publishing date 2024-01-21
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 995528-8
    ISSN 1466-447X ; 0264-0414
    ISSN (online) 1466-447X
    ISSN 0264-0414
    DOI 10.1080/02640414.2024.2305007
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    Zs.A 2388: Show issues Location:
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  4. Article ; Online: Not just antibodies: B cells and T cells mediate immunity to COVID-19.

    Cox, Rebecca J / Brokstad, Karl A

    Nature reviews. Immunology

    2020  Volume 20, Issue 10, Page(s) 581–582

    MeSH term(s) Antibodies, Viral/biosynthesis ; Asymptomatic Diseases ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; Betacoronavirus/immunology ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Cytokines/biosynthesis ; Humans ; Immunity, Cellular ; Immunity, Humoral ; Immunization, Passive/methods ; Immunoglobulin G/biosynthesis ; Immunoglobulin M/biosynthesis ; Immunologic Memory ; Lymphocyte Activation ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Severity of Illness Index ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/virology ; Time Factors
    Chemical Substances Antibodies, Viral ; Cytokines ; Immunoglobulin G ; Immunoglobulin M
    Keywords covid19
    Language English
    Publishing date 2020-08-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-020-00436-4
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  5. Article ; Online: Assessment of a Multispecies Probiotic Supplement for Relief of Seasonal Allergic Rhinitis: A Randomized Double-Blind Placebo-Controlled Trial.

    Cox, Amanda J / Ramsey, Rebecca / Ware, Robert S / Besseling-van der Vaart, Isolde / Cripps, Allan W / West, Nicholas P

    Journal of integrative and complementary medicine

    2023  Volume 29, Issue 5, Page(s) 313–320

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Humans ; Conjunctivitis ; Double-Blind Method ; Probiotics/therapeutic use ; Quality of Life ; Rhinitis, Allergic, Seasonal/drug therapy
    Language English
    Publishing date 2023-02-20
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 2768-3613
    ISSN (online) 2768-3613
    DOI 10.1089/jicm.2022.0734
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  7. Article ; Online: Not just antibodies

    Cox, Rebecca J. / Brokstad, Karl A.

    Nature Reviews Immunology

    B cells and T cells mediate immunity to COVID-19

    2020  Volume 20, Issue 10, Page(s) 581–582

    Keywords Immunology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-020-00436-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5565: Show issues Location:
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  8. Article ; Online: Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond.

    Aslakson, Rebecca A / Cox, Christopher E / Baggs, Judith G / Curtis, J Randall

    Critical care medicine

    2021  Volume 49, Issue 10, Page(s) 1626–1637

    MeSH term(s) Empathy ; Humans ; Intensive Care Units/organization & administration ; Intensive Care Units/statistics & numerical data ; Professional-Patient Relations ; Terminal Care/methods ; Terminal Care/psychology
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005208
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    Zs.A 1261: Show issues Location:
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  9. Article ; Online: Seroconversion in household members of COVID-19 outpatients.

    Cox, Rebecca J / Brokstad, Karl A / Krammer, Florian / Langeland, Nina

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 2, Page(s) 168

    MeSH term(s) Antibodies, Viral ; COVID-19 ; China ; Humans ; Outpatients ; Retrospective Studies ; SARS-CoV-2 ; Seroconversion
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-06-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30466-7
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    Zs.A 5743: Show issues Location:
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  10. Article: Muddy

    Bannister, Scott / Greasley, Alinka E / Cox, Trevor J / Akeroyd, Michael A / Barker, Jon / Fazenda, Bruno / Firth, Jennifer / Graetzer, Simone N / Roa Dabike, Gerardo / Vos, Rebecca R / Whitmer, William M

    Frontiers in psychology

    2024  Volume 15, Page(s) 1310176

    Abstract: Introduction: Previous work on audio quality evaluation has demonstrated a developing convergence of the key perceptual attributes underlying judgments of quality, such as timbral, spatial and technical attributes. However, across existing research ... ...

    Abstract Introduction: Previous work on audio quality evaluation has demonstrated a developing convergence of the key perceptual attributes underlying judgments of quality, such as timbral, spatial and technical attributes. However, across existing research there remains a limited understanding of the crucial perceptual attributes that inform audio quality evaluation for people with hearing loss, and those who use hearing aids. This is especially the case with music, given the unique problems it presents in contrast to human speech.
    Method: This paper presents a sensory evaluation study utilising descriptive analysis methods, in which a panel of hearing aid users collaborated, through consensus, to identify the most important perceptual attributes of music audio quality and developed a series of rating scales for future listening tests. Participants (
    Results: Findings show that there were seven key perceptual dimensions underlying music audio quality (
    Discussion: We outline how these perceptual attributes align with extant literature, how attribute rating instruments might be used in future work, and the importance of better understanding the music listening difficulties of people with varied profiles of hearing loss.
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2024.1310176
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