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  1. Article ; Online: Religion, spirituality and improved glycemic control among people with type 2 diabetes: A systematic review.

    Weber, Jonathan M / Doolittle, Benjamin R

    International journal of psychiatry in medicine

    2023  Volume 58, Issue 6, Page(s) 617–636

    Abstract: Objective: This systematic review investigates the association between measures of religiosity or spirituality (R/S) and glycemic control in patients with type 2 diabetes.: Methods: A systematic literature review was conducted for all English ... ...

    Abstract Objective: This systematic review investigates the association between measures of religiosity or spirituality (R/S) and glycemic control in patients with type 2 diabetes.
    Methods: A systematic literature review was conducted for all English language articles published between 1966 and August 2022 in six relevant databases: PubMed, PSYCHinfo, CINAHL, ATLA, Scopus, Sociological Abstracts, and the Cochrane Central Register of Controlled Clinical Trials. Search terms for religious variables included, "religion", "religiosity", "spirituality", "religious attendance". Search terms for diabetes outcomes included, "diabetes", "hemoglobin A1c", "blood glucose", "glycemic control." The protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO).
    Results: A total of 758 studies examining correlations between R/S and glycemic control were screened from relevant databases. Forty studies were evaluated for eligibility and inclusion. Eight studies were selected and analyzed. Three studies showed positive associations, two studies showed positive and neutral associations, two studies showed positive and negative associations, and one study showed a neutral association. Limitations included small sample sizes and heterogeneity of study designs.
    Conclusion: Involvement in religious and spiritual practices may be associated with improved glycemic control in patients with type 2 diabetes. Specific mechanisms for associations may be partially explained by more effective self-management practices, increased positive social contacts, and regular community support. Further research is needed to clarify these associations.
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 220669-9
    ISSN 1541-3527 ; 0091-2174
    ISSN (online) 1541-3527
    ISSN 0091-2174
    DOI 10.1177/00912174231176171
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  2. Article ; Online: Reverse Shoulder Arthroplasty for Irreparable Rotator Cuff Tear After Radial to Axillary End-to-Side Transfer: A Case Report.

    Protzuk, Omar / Schmidt, R Cole / Craig, Justin M / Weber, Matt / Isaacs, Jonathan / O'Connell, Robert

    JBJS case connector

    2024  Volume 14, Issue 1

    Abstract: Case: A 60-year-old man sustained a massive irreparable rotator cuff tear and axillary nerve palsy with deltoid dysfunction after an anterior shoulder dislocation. He underwent staged reverse end-to-side radial-to-axillary nerve transfer with return of ... ...

    Abstract Case: A 60-year-old man sustained a massive irreparable rotator cuff tear and axillary nerve palsy with deltoid dysfunction after an anterior shoulder dislocation. He underwent staged reverse end-to-side radial-to-axillary nerve transfer with return of deltoid function allowing for subsequent reverse shoulder arthroplasty. At 1 year postoperatively, he returned to full activity.
    Conclusion: Irreparable rotator cuff tears complicated by axillary nerve palsy can be effectively treated with a staged approach of nerve transfer followed by reverse shoulder arthroplasty.
    MeSH term(s) Male ; Humans ; Middle Aged ; Rotator Cuff Injuries/complications ; Rotator Cuff Injuries/surgery ; Arthroplasty, Replacement, Shoulder ; Arthroplasty ; Paralysis
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI e23.00526
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  3. Article ; Online: Time-to-event estimands and loss to follow-up in oncology in light of the estimands guidance.

    Siegel, Jonathan M / Weber, Hans-Jochen / Englert, Stefan / Liu, Feng / Casey, Michelle

    Pharmaceutical statistics

    2024  

    Abstract: Time-to-event estimands are central to many oncology clinical trials. The estimands framework (addendum to the ICH E9 guideline) calls for precisely defining the treatment effect of interest to align with the clinical question of interest and requires ... ...

    Abstract Time-to-event estimands are central to many oncology clinical trials. The estimands framework (addendum to the ICH E9 guideline) calls for precisely defining the treatment effect of interest to align with the clinical question of interest and requires predefining the handling of intercurrent events (ICEs) that occur after treatment initiation and "affect either the interpretation or the existence of the measurements associated with the clinical question of interest." We discuss a practical problem in clinical trial design and execution, that is, in some clinical contexts it is not feasible to systematically follow patients to an event of interest. Loss to follow-up in the presence of intercurrent events can affect the meaning and interpretation of the study results. We provide recommendations for trial design, stressing the need for close alignment of the clinical question of interest and study design, impact on data collection, and other practical implications. When patients cannot be systematically followed, compromise may be necessary to select the best available estimand that can be feasibly estimated under the circumstances. We discuss the use of sensitivity and supplementary analyses to examine assumptions of interest.
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2083706-9
    ISSN 1539-1612 ; 1539-1604
    ISSN (online) 1539-1612
    ISSN 1539-1604
    DOI 10.1002/pst.2386
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  4. Article ; Online: A pilot study to evaluate clinical factors associated with iron and ferritin elevations during pediatric extracorporeal membrane oxygenation.

    Sam, Ashley E / Weber, Zachary / Peña, Alejandra / Henderson, Cody / King, Jonathan M / Carr, Nicholas R

    Perfusion

    2023  Volume 39, Issue 3, Page(s) 585–592

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Child ; Extracorporeal Membrane Oxygenation/adverse effects ; Extracorporeal Membrane Oxygenation/methods ; Pilot Projects ; Iron ; Ferritins ; Hemolysis ; Prospective Studies ; Retrospective Studies
    Chemical Substances Iron (E1UOL152H7) ; Ferritins (9007-73-2)
    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591231154750
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  5. Article ; Online: A novel intracorporeal right ventricular assist device implantation technique in a young patient.

    Mavroudis, Constantine D / Grasty, Madison A / Restaino, Kathryn / Montgomery, Catherine M / Pettit, Alee N / O'Connor, Matthew J / Wittlieb-Weber, Carol / Edelson, Jonathan B / Edwards, Jonathan / Berger, Justin / Lin, Kimberly / Rossano, Joseph / Maeda, Katsuhide

    JTCVS techniques

    2023  Volume 23, Page(s) 89–91

    Language English
    Publishing date 2023-11-04
    Publishing country United States
    Document type Case Reports
    ISSN 2666-2507
    ISSN (online) 2666-2507
    DOI 10.1016/j.xjtc.2023.10.025
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  6. Article ; Online: Orientation dependence of R

    Bartels, Lara M / Doucette, Jonathan / Birkl, Christoph / Zhang, Yuting / Weber, Alexander M / Rauscher, Alexander

    NeuroImage

    2022  Volume 264, Page(s) 119702

    Abstract: In MRI the transverse relaxation rate, ... ...

    Abstract In MRI the transverse relaxation rate, R
    MeSH term(s) Infant, Newborn ; Humans ; Diffusion Tensor Imaging/methods ; Image Processing, Computer-Assisted/methods ; Brain/diagnostic imaging ; White Matter/diagnostic imaging ; Myelin Sheath ; Water ; Anisotropy
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2022-10-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2022.119702
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  7. Article: Author Correction: Systematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight.

    Elias, Antoine / Weber, Tobias / Green, David A / Harris, Katie M / Laws, Jonathan M / Greaves, Danielle K / Kim, David S / Mazzolai-Duchosal, Lucia / Roberts, Lara / Petersen, Lonnie G / Limper, Ulrich / Bergauer, Andrej / Elias, Michael / Winnard, Andrew / Goswami, Nandu

    NPJ microgravity

    2024  Volume 10, Issue 1, Page(s) 17

    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2823626-9
    ISSN 2373-8065
    ISSN 2373-8065
    DOI 10.1038/s41526-024-00362-y
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  8. Article ; Online: A hyperbaric aerodynamic levitator for containerless materials research.

    Boland, Sydney E / Wilke, Stephen K / Scott, Jonathan A / Schlossberg, Sarah M / Ivaschenko, Alex / Weber, Richard J K / Lipke, David W

    The Review of scientific instruments

    2023  Volume 94, Issue 5

    Abstract: A hyperbaric aerodynamic levitator has been developed for containerless materials research at specimen temperatures exceeding 2000 °C and pressures up to 10.3 MPa (1500 psi). This report describes the prototype instrument design and observations of the ... ...

    Abstract A hyperbaric aerodynamic levitator has been developed for containerless materials research at specimen temperatures exceeding 2000 °C and pressures up to 10.3 MPa (1500 psi). This report describes the prototype instrument design and observations of the influence of specimen size, density, pressure, and flow rate on levitation behavior. The effect of pressure on heat transfer was also assessed by studying the heating and cooling behavior of levitated Al2O3 liquids. A threefold increase in the convective heat transfer coefficient was estimated as pressure increased to 10.3 MPa. The results demonstrate that hyperbaric aerodynamic levitation is a promising technique for containerless materials research at high gas pressures.
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209865-9
    ISSN 1089-7623 ; 0034-6748
    ISSN (online) 1089-7623
    ISSN 0034-6748
    DOI 10.1063/5.0148455
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  9. Article ; Online: Liquid spherical shells are a non-equilibrium steady state of active droplets.

    Bergmann, Alexander M / Bauermann, Jonathan / Bartolucci, Giacomo / Donau, Carsten / Stasi, Michele / Holtmannspötter, Anna-Lena / Jülicher, Frank / Weber, Christoph A / Boekhoven, Job

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 6552

    Abstract: Liquid-liquid phase separation yields spherical droplets that eventually coarsen to one large, stable droplet governed by the principle of minimal free energy. In chemically fueled phase separation, the formation of phase-separating molecules is coupled ... ...

    Abstract Liquid-liquid phase separation yields spherical droplets that eventually coarsen to one large, stable droplet governed by the principle of minimal free energy. In chemically fueled phase separation, the formation of phase-separating molecules is coupled to a fuel-driven, non-equilibrium reaction cycle. It thus yields dissipative structures sustained by a continuous fuel conversion. Such dissipative structures are ubiquitous in biology but are poorly understood as they are governed by non-equilibrium thermodynamics. Here, we bridge the gap between passive, close-to-equilibrium, and active, dissipative structures with chemically fueled phase separation. We observe that spherical, active droplets can undergo a morphological transition into a liquid, spherical shell. We demonstrate that the mechanism is related to gradients of short-lived droplet material. We characterize how far out of equilibrium the spherical shell state is and the chemical power necessary to sustain it. Our work suggests alternative avenues for assembling complex stable morphologies, which might already be exploited to form membraneless organelles by cells.
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-42344-w
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  10. Article ; Online: Chemical Kinetics and Mass Action in Coexisting Phases.

    Bauermann, Jonathan / Laha, Sudarshana / McCall, Patrick M / Jülicher, Frank / Weber, Christoph A

    Journal of the American Chemical Society

    2022  Volume 144, Issue 42, Page(s) 19294–19304

    Abstract: The kinetics of chemical reactions are determined by the law of mass action, which has been successfully applied to homogeneous, dilute mixtures. At nondilute conditions, interactions among the components can give rise to coexisting phases, which can ... ...

    Abstract The kinetics of chemical reactions are determined by the law of mass action, which has been successfully applied to homogeneous, dilute mixtures. At nondilute conditions, interactions among the components can give rise to coexisting phases, which can significantly alter the kinetics of chemical reactions. Here, we derive a theory for chemical reactions in coexisting phases at phase equilibrium. We show that phase equilibrium couples the rates of chemical reactions of components with their diffusive exchanges between the phases. Strikingly, the chemical relaxation kinetics can be represented as a flow along the phase equilibrium line in the phase diagram. A key finding of our theory is that differences in reaction rates between coexisting phases stem solely from phase-dependent reaction rate coefficients. Our theory is key to interpreting how concentration levels of reactive components in condensed phases control chemical reaction rates in synthetic and biological systems.
    MeSH term(s) Kinetics ; Diffusion
    Language English
    Publishing date 2022-10-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.2c06265
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