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  1. Article ; Online: Novel coronavirus 2019 pneumonia in a kidney transplant recipient.

    Namazee, Najmeh / Mahmoudi, Hilda / Afzal, Payman / Ghaffari, Sina

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2020  Volume 20, Issue 9, Page(s) 2599–2601

    Abstract: The COVID-19 pandemic is spreading worldwide and the impact of the disease in transplant patients is evolving. In this case report, we presented a 63-year-old female kidney transplant recipient who presented with dyspnea and cough and was diagnosed with ... ...

    Abstract The COVID-19 pandemic is spreading worldwide and the impact of the disease in transplant patients is evolving. In this case report, we presented a 63-year-old female kidney transplant recipient who presented with dyspnea and cough and was diagnosed with COVID-19 pneumonia. On the fourth day of admission, the patient's condition worsened. Therefore, the immunosuppressive medications were discontinued, and hydrocortisone was started. The patient died on the fifth day.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Female ; Graft Rejection/prevention & control ; Humans ; Immunosuppression Therapy/methods ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/methods ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Transplant Recipients
    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.15999
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  2. Article: Novel coronavirus 2019 pneumonia in a kidney transplant recipient

    Namazee, Najmeh / Mahmoudi, Hilda / Afzal, Payman / Ghaffari, Sina

    Am J Transplant

    Abstract: The COVID-19 pandemic is spreading worldwide and the impact of the disease in transplant patients is evolving. In this case report, we presented a 63-year-old female kidney transplant recipient who presented with dyspnea and cough and was diagnosed with ... ...

    Abstract The COVID-19 pandemic is spreading worldwide and the impact of the disease in transplant patients is evolving. In this case report, we presented a 63-year-old female kidney transplant recipient who presented with dyspnea and cough and was diagnosed with COVID-19 pneumonia. On the fourth day of admission, the patient's condition worsened. Therefore, the immunosuppressive medications were discontinued, and hydrocortisone was started. The patient died on the fifth day.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #245455
    Database COVID19

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  3. Article ; Online: A Report of a Young Man with Fever of Unknown Origin and Hyperferritinemia

    Javad Khodadady / Najmeh Namazee

    Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 9, Iss 3, Pp 69-

    Adult-onset Still\'s Disease

    2015  Volume 72

    Abstract: Background and Objectives: Adult onset Still’s disease (AOSD) is a rare systemic, inflammatory disorder with unknown etiology. This disorder is characterized by spiking fever, evanescent rash and joint involvement. Elevated CRP, ferritin levels, white ... ...

    Abstract Background and Objectives: Adult onset Still’s disease (AOSD) is a rare systemic, inflammatory disorder with unknown etiology. This disorder is characterized by spiking fever, evanescent rash and joint involvement. Elevated CRP, ferritin levels, white blood cells and platelet counts are some laboratory features of this disorder. hyperferritinemia may play a useful role in diagnosis and monitoring the disease. Case Report: In this article a 27 year old male with fever, sore throat, myalgia, splenomegaly and hyperferritinemia is described, who was diagnosed and treated as a case of adult onset Stillchr('39')s disease.
    Keywords arthritis ; juvenile ; still\'s disease ; adult-onset ; fever of unknown origin ; hyperferritinemia ; rheumatoid ; Medicine (General) ; R5-920
    Language Persian
    Publishing date 2015-05-01T00:00:00Z
    Publisher Qom University of Medical Sciences
    Document type Article ; Online
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  4. Article: Close contact precautions could prevent an outbreak of crimean-congo hemorrhagic Fever: a case series report from southern part of tehran.

    Mardani, Masoud / Namazee, Najmeh

    International journal of preventive medicine

    2013  Volume 4, Issue 6, Page(s) 715–719

    Abstract: Between the end of June and the middle of July 2011, an outbreak of Crimean-Congo Hemorrhagic Fever occurred in southern part of Tehran, Iran. This study reports clinical, laboratory findings and outcome of six cases, who were all consanguine. Index case ...

    Abstract Between the end of June and the middle of July 2011, an outbreak of Crimean-Congo Hemorrhagic Fever occurred in southern part of Tehran, Iran. This study reports clinical, laboratory findings and outcome of six cases, who were all consanguine. Index case who was livestock-worker died with hemorrhagic manifestations; thereafter his pregnant wife, three brothers, mother-in-law and his pregnant sister-in-law were admitted and except for the latter, ribavirin was administered. The brother with close contact with body fluids and blood of index case, died with hemorrhage. Low platelet, high aminotransferases and elevated PT, PTT were detected in this case. Skin manifestations were present in five cases. Only in one case RT-PCR and IgM serology were reported as positive for CCHF virus by reference laboratory. In endemic areas, high index of suspicion should be kept in mind in successfully finding and treating cases in early phase of the disease.
    Language English
    Publishing date 2013-08-06
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
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  5. Article ; Online: Close contact precautions could prevent an outbreak of crimean-congo hemorrhagic fever

    Masoud Mardani / Najmeh Namazee

    International Journal of Preventive Medicine, Vol 4, Iss 6, Pp 715-

    A case series report from southern part of Tehran

    2013  Volume 719

    Abstract: Between the end of June and the middle of July 2011, an outbreak of Crimean-Congo Hemorrhagic Fever occurred in southern part of Tehran, Iran. This study reports clinical, laboratory findings and outcome of six cases, who were all consanguine. Index case ...

    Abstract Between the end of June and the middle of July 2011, an outbreak of Crimean-Congo Hemorrhagic Fever occurred in southern part of Tehran, Iran. This study reports clinical, laboratory findings and outcome of six cases, who were all consanguine. Index case who was livestock-worker died with hemorrhagic manifestations; thereafter his pregnant wife, three brothers, mother-in-law and his pregnant sister-in-law were admitted and except for the latter, ribavirin was administered. The brother with close contact with body fluids and blood of index case, died with hemorrhage. Low platelet, high aminotransferases and elevated PT, PTT were detected in this case. Skin manifestations were present in five cases. Only in one case RT-PCR and IgM serology were reported as positive for CCHF virus by reference laboratory. In endemic areas, high index of suspicion should be kept in mind in successfully finding and treating cases in early phase of the disease.
    Keywords Crimean-Congo hemorrhagic fever ; tick-borne disease ; outbreak ; ribavirin prophylaxis ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
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  6. Article ; Online: Real response to therapy in chronic hepatitis C virus patients: a study from iran.

    Namazee, Najmeh / Sali, Shahnaz / Asadi, Sorour / Shafiei, Mostafa / Behnava, Bita / Alavian, Seyed Moayed

    Hepatitis monthly

    2012  Volume 12, Issue 9, Page(s) e6151

    Abstract: Background: Despite significant advances in the treatment of chronic hepatitis C in the past decades, factors which can affect response rates to combination therapy; peginterferon and ribavirin, are still under study and reaching sustained virological ... ...

    Abstract Background: Despite significant advances in the treatment of chronic hepatitis C in the past decades, factors which can affect response rates to combination therapy; peginterferon and ribavirin, are still under study and reaching sustained virological response (SVR) is affected by several different factors.
    Objectives: To investigate predictor factors contributing to SVR in Iranian patients.
    Patients and methods: The present non-randomized, clinical trial was conducted on 100 patients referred to the Tehran Hepatitis Center in 2009-2011. The patients were administered combined peginterferon α-2a-ribavirin treatment, based on the standard protocol of the Iranian Ministry of Health. At the end of the treatment, the SVR rate and predictors were evaluated.
    Results: The mean age of the patients was 42 and 78% were male. Genotype 1a was the most common (70%) and 55% of patients were treatment naïve. The outcomes showed that 12%, 16% and 22% patients were; non-responders, breakthroughs and relapsers, respectively, while 50% of the patients reached SVR. Patients reaching SVR were aged 40 years or lower, they were less likely to have been a non-responder in prior treatments, more likely to have a non-1a genotype and a higher number had an HCV RNA of less than 600 000 IU/ml. The multivariate analysis showed that an age of 40 or lower (OR = 3.74, CI95% = 1.52-9.22), a non-1a genotype (OR = 3.71, CI 95% = 1.40-9.81) and an HCV RNA less than 600 000 IU/ml (OR = 2.52, CI 95% = 1.03-6.15) may be useful SVR predictors.
    Conclusions: The findings of the present study showed that half of the patients reached SVR through combined peginterferon α-2a and ribavirin treatment, the majority of whom had genotype 3a and a minority had genotype 1a. In addition, an age of 40 or lower, non-1a genotype and a viral load less than 600 000 IU/ml were strong SVR predictors.
    Language English
    Publishing date 2012-09-15
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2236753-6
    ISSN 1735-3408 ; 1735-143X
    ISSN (online) 1735-3408
    ISSN 1735-143X
    DOI 10.5812/hepatmon.6151
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  7. Article: Combined use of growth hormone and gonadotropin-releasing hormone analogue in short normal adolescent girls: a survey from Iran.

    Karamizadeh, Zohreh / Kashef, Mohammad Amin / Jalaeian, Hamed / Namazee, Najmeh

    The Kaohsiung journal of medical sciences

    2006  Volume 22, Issue 4, Page(s) 161–165

    Abstract: Combined therapy with gonadotropin-releasing hormone (GnRH) analogue and growth hormone (GH) has been used to increase the height of adolescents who are not GH deficient and who have normally timed puberty. Its use, however, is still controversial. For 2 ...

    Abstract Combined therapy with gonadotropin-releasing hormone (GnRH) analogue and growth hormone (GH) has been used to increase the height of adolescents who are not GH deficient and who have normally timed puberty. Its use, however, is still controversial. For 2 years simultaneously, we treated eight healthy girls with very low predicted adult height (PAH < 145 cm) who were entering into normally timed puberty. The GnRH analogue triptorelin pamoate (Decapeptyl, 100 microg/kg intramuscularly every 4 weeks) and GH (0.1 IU/kg/day subcutaneously, 6 days/week) were administered. The mean chronologic age (CA) of our patients was 11.01 +/- 0.95 years, and mean bone age (BA) was 12.25 +/- 1.13 years. With a height of 131.50 +/- 5.83 cm (-2.37 +/- 0.35 SD below the mean) and PAH of 140.87 +/- 3.53 cm, they were all in Tanner stage 2-3 of puberty (except one patient in stage 4). In all cases, GH and thyroid hormone deficiency were ruled out before the study began. Height and BA were measured immediately after discontinuation of therapy. PAH was determined before and at the end of therapy. Combined treatment resulted in a 4.13 +/- 1.19 cm increase in PAH (p < 0.01). Height increased significantly to 142.66 +/- 3.54 cm at the end of treatment (p < 0.01). Height standard deviation score for CA increased from -2.37 +/- 0.35 to -2.32 +/- 0.67, showing no significant improvement (p = 0.5). Height age (HA)/BA ratio and BA/CA ratio both demonstrated significant growth during the treatment (p < 0.03 and p < 0.01, respectively), whereas HA/CA ratio did not improve significantly (p < 0.32). During treatment, puberty was completely suppressed in all cases. Combination therapy with GnRH analogue and GH resulted in significant improvement in height and PAH during therapy. Additional, and perhaps more long-term, studies are required to show whether this kind of treatment is effective in improving final adult height. The cost-benefit of such therapies should also be taken into account.
    MeSH term(s) Body Height/drug effects ; Child ; Drug Therapy, Combination ; Female ; Growth Disorders/drug therapy ; Growth Hormone/administration & dosage ; Humans ; Triptorelin Pamoate/administration & dosage ; Triptorelin Pamoate/analogs & derivatives
    Chemical Substances Triptorelin Pamoate (57773-63-4) ; Growth Hormone (9002-72-6)
    Language English
    Publishing date 2006-04
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 639302-0
    ISSN 1607-551X ; 0257-5655
    ISSN 1607-551X ; 0257-5655
    DOI 10.1016/S1607-551X(09)70301-8
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  8. Article ; Online: Combined Use of Growth Hormone and Gonadotropin-Releasing Hormone Analogue in Short Normal Adolescent Girls

    Zohreh Karamizadeh / Mohammad Amin Kashef / Hamed Jalaeian / Najmeh Namazee

    Kaohsiung Journal of Medical Sciences, Vol 22, Iss 4, Pp 161-

    A Survey from Iran

    2006  Volume 165

    Abstract: Combined therapy with gonadotropin-releasing hormone (GnRH) analogue and growth hormone (GH) has been used to increase the height of adolescents who are not GH deficient and who have normally timed puberty. Its use, however, is still controversial. For 2 ...

    Abstract Combined therapy with gonadotropin-releasing hormone (GnRH) analogue and growth hormone (GH) has been used to increase the height of adolescents who are not GH deficient and who have normally timed puberty. Its use, however, is still controversial. For 2 years simultaneously, we treated eight healthy girls with very low predicted adult height (PAH < 145 cm) who were entering into normally timed puberty. The GnRH analogue triptorelin pamoate (Decapeptyl, 100 μg/kg intramuscularly every 4 weeks) and GH (0.1 IU/kg/day subcutaneously, 6 days/week) were administered. The mean chronologic age (CA) of our patients was 11.01 ± 0.95 years, and mean bone age (BA) was 12.25 ± 1.13 years. With a height of 131.50 ± 5.83 cm (−2.37 ± 0.35 SD below the mean) and PAH of 140.87 ± 3.53 cm, they were all in Tanner stage 2-3 of puberty (except one patient in stage 4). In all cases, GH and thyroid hormone deficiency were ruled out before the study began. Height and BA were measured immediately after discontinuation of therapy. PAH was determined before and at the end of therapy. Combined treatment resulted in a 4.13 ± 1.19 cm increase in PAH (p < 0.01). Height increased significantly to 142.66 ± 3.54 cm at the end of treatment (p < 0.01). Height standard deviation score for CA increased from −2.37 ± 0.35 to −2.32 ± 0.67, showing no significant improvement (p = 0.5). Height age (HA)/BA ratio and BA/CA ratio both demonstrated significant growth during the treatment (p < 0.03 and p < 0.01, respectively), whereas HA/CA ratio did not improve significantly (p < 0.32). During treatment, puberty was completely suppressed in all cases. Combination therapy with GnRH analogue and GH resulted in significant improvement in height and PAH during therapy. Additional, and perhaps more long-term, studies are required to show whether this kind of treatment is effective in improving final adult height. The cost-benefit of such therapies should also be taken into account.
    Keywords short normal adolescents ; growth hormone (GH) ; gonadotropin-releasing hormone (GnRH) ; height ; Medicine (General) ; R5-920
    Subject code 616 ; 630
    Language English
    Publishing date 2006-04-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
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