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  1. Article: Discussion of “Boundary layer development over non-uniform sand rough bed channel”, by Anurag Sharma and Bimlesh Kumar (2017)

    Singh, Santosh Kumar / Debnath, Koustuv

    ISH journal of hydraulic engineering. 2019 Sept. 2, v. 25, no. 3

    2019  

    Abstract: This discussion provides highlights with regard to determination of the appropriate length for boundary layer development over non-uniform sand bed channels with and without seepage. It is demonstrated that the compound effects of Kármán’s coefficient κ ... ...

    Abstract This discussion provides highlights with regard to determination of the appropriate length for boundary layer development over non-uniform sand bed channels with and without seepage. It is demonstrated that the compound effects of Kármán’s coefficient κ and virtual origin should be accounted to quantify the behaviour of roughness length over non-uniform sand bed channels with seepage.
    Keywords roughness length ; sand ; seepage
    Language English
    Dates of publication 2019-0902
    Size p. 282.
    Publishing place Taylor & Francis
    Document type Article
    ISSN 2164-3040
    DOI 10.1080/09715010.2017.1417755
    Database NAL-Catalogue (AGRICOLA)

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  2. Book ; Online ; E-Book: Nanoarchitectonics for Brain Drug Delivery

    Kumar Singh, Anurag / Chaturvedi, Vivek K. / Singh, Jay

    (Advances in Bionanotechnology Series)

    2024  

    Abstract: This book discusses basics of brain diseases and role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and need for novel drug delivery approaches. It highlights the current ...

    Author's details edited by Anurag Kumar Singh, Vivek K. Chaturvedi, and Jay Singh
    Series title Advances in Bionanotechnology Series
    Abstract "This book discusses basics of brain diseases and role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and need for novel drug delivery approaches. It highlights the current route for the intranasal advanced drug delivery systems for brain diseases. It also discusses the innovative categories of drug delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Includes overview of brain diseases and highlights the need for novel drug delivery approaches. Focusses on theoretical aspects of the advanced drug delivery systems for brain diseases including challenges and progress in nose-to-brain delivery. Provides an overview of the technological approaches and their implications in the neurodegenerative disorders, CNS, and brain drug delivery in brain cancer. Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS. Review role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders. This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology"--
    MeSH term(s) Brain Diseases/drug therapy. ; Neurodegenerative Diseases/drug therapy. ; Nanoparticle Drug Delivery System/chemistry. ; Nanoparticle Drug Delivery System/therapeutic use. ; Nanoparticles/therapeutic use. ; Biotechnology/methods.
    Keywords Nanomedicine ; Drug carriers (Pharmacy)
    Subject code 615.19
    Language English
    Size 1 online resource (0 pages)
    Edition First edition.
    Publisher CRC Press
    Publishing place Boca Raton, FL
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-03-266196-8 ; 1-003-85184-3 ; 9781032661957 ; 978-1-03-266196-4 ; 978-1-003-85184-4 ; 103266195X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: From genome to clinic: The power of translational bioinformatics in improving human health.

    Singh, Satyendra / Pandey, Anurag Kumar / Prajapati, Vijay Kumar

    Advances in protein chemistry and structural biology

    2024  Volume 139, Page(s) 1–25

    Abstract: Translational bioinformatics (TBI) has transformed healthcare by providing personalized medicine and tailored treatment options by integrating genomic data and clinical information. In recent years, TBI has bridged the gap between genome and clinical ... ...

    Abstract Translational bioinformatics (TBI) has transformed healthcare by providing personalized medicine and tailored treatment options by integrating genomic data and clinical information. In recent years, TBI has bridged the gap between genome and clinical data because of significant advances in informatics like quantum computing and utilizing state-of-the-art technologies. This chapter discusses the power of translational bioinformatics in improving human health, from uncovering disease-causing genes and variations to establishing new therapeutic techniques. We discuss key application areas of bioinformatics in clinical genomics, such as data sources and methods used in translational bioinformatics, the impact of translational bioinformatics on human health, and how machine learning and artificial intelligence are being used to mine vast amounts of data for drug development and precision medicine. We also look at the problems, constraints, and ethical concerns connected with exploiting genomic data and the future of translational bioinformatics and its potential impact on medicine and human health. Ultimately, this chapter emphasizes the great potential of translational bioinformatics to alter healthcare and enhance patient outcomes.
    MeSH term(s) Humans ; Artificial Intelligence ; Computing Methodologies ; Quantum Theory ; Computational Biology ; Genomics
    Language English
    Publishing date 2024-02-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2473077-4
    ISSN 1876-1631 ; 1876-1623
    ISSN (online) 1876-1631
    ISSN 1876-1623
    DOI 10.1016/bs.apcsb.2023.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: α-Carbonyl sulfoxonium ylides in transition metal-catalyzed C-H activation: a safe carbene precursor and a weak directing group.

    Singh, Anurag / Kumar, Shreemoyee / Volla, Chandra M R

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 5, Page(s) 879–909

    Abstract: Transition metal-catalyzed cross-coupling of ... ...

    Abstract Transition metal-catalyzed cross-coupling of sp
    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d2ob01835g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Thermal hydrolysis of sewage sludge: Improvement in biogas generation and prediction of global warming potential.

    Singh, Diwakar Kumar / Garg, Anurag

    Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA

    2023  Volume 42, Issue 1, Page(s) 51–58

    Abstract: Anaerobic digestion (AD) is a prominent treatment method for the sludge produced from sewage treatment plants. Poor solid reduction and longer retention time are the main drawbacks of AD. Thermal hydrolysis (TH) is a potential pretreatment method for ... ...

    Abstract Anaerobic digestion (AD) is a prominent treatment method for the sludge produced from sewage treatment plants. Poor solid reduction and longer retention time are the main drawbacks of AD. Thermal hydrolysis (TH) is a potential pretreatment method for solubilization of sewage sludge (SS) solids thereby improving biogas production during AD post-treatment. In this study, the SS sample (total solids = 1.75 wt% and total chemical oxygen demand (COD) = 15,450 mg L
    MeSH term(s) Sewage ; Biofuels ; Anaerobiosis ; Hydrolysis ; Global Warming ; Waste Disposal, Fluid/methods ; Methane
    Chemical Substances Sewage ; Biofuels ; Methane (OP0UW79H66)
    Language English
    Publishing date 2023-05-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1480483-9
    ISSN 1096-3669 ; 1399-3070 ; 0734-242X
    ISSN (online) 1096-3669 ; 1399-3070
    ISSN 0734-242X
    DOI 10.1177/0734242X231171044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Technological advancements in viral vector designing and optimization for therapeutic applications.

    Singh, Satyendra / Pandey, Anurag Kumar / Malemnganba, Takhellambam / Prajapati, Vijay Kumar

    Advances in protein chemistry and structural biology

    2024  Volume 139, Page(s) 57–87

    Abstract: Viral vector engineering is critical to the advancement of several sectors of biotechnology, gene therapy, and vaccine development. These vectors were produced from viruses, were employed to deliver therapeutic genes or to alter biological processes. The ...

    Abstract Viral vector engineering is critical to the advancement of several sectors of biotechnology, gene therapy, and vaccine development. These vectors were produced from viruses, were employed to deliver therapeutic genes or to alter biological processes. The potential for viral vectors to improve the precision, safety, and efficiency of therapeutic interventions has boosted their demand. The dynamic interplay between technological advancements and computational tools in establishing the landscape of viral vector engineering and vector optimization for therapeutic reasons is discussed in this chapter. It also emphasizes the importance of in silico techniques in maximizing vector potential for therapeutics and many phases of viral vector engineering, from genomic analysis to computer modelling and advancements to improve precise gene delivery. High-throughput screening propels the expedited process of vector selection, and computational techniques to analyze complex omics data to further enhance vector capabilities have been discussed. As in silico models reveal insights into off-target effects and integration sites, vector safety (biodistribution and toxicity) remains a crucial part and bridges the gap between preclinical and clinical investigations. Despite the limitations, this chapter depicts a future in which technology and computing merge to catapult viral vector therapy into an era of boundless possibilities.
    MeSH term(s) Tissue Distribution ; Computer Simulation ; Genetic Therapy ; Genomics ; High-Throughput Screening Assays
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2473077-4
    ISSN 1876-1631 ; 1876-1623
    ISSN (online) 1876-1631
    ISSN 1876-1623
    DOI 10.1016/bs.apcsb.2023.11.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Tagging Efficiency of

    Pal, Deepak Kumar / Singh, Dhananjay Kumar / Deswal, Satyawati / Pathak, Anurag

    World journal of nuclear medicine

    2022  Volume 22, Issue 1, Page(s) 1–6

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2022-09-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2911903-0
    ISSN 1607-3312 ; 1450-1147
    ISSN (online) 1607-3312
    ISSN 1450-1147
    DOI 10.1055/s-0042-1757255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ovarian aspergilloma in an immunocompetent patient masquerading as ovarian neoplasm.

    Singh, Gyanendra / Singh, Anurag / Verma, Anuragani / Verma, Yogendra / Kumar, Neeraj

    Archive of clinical cases

    2023  Volume 10, Issue 1, Page(s) 39–41

    Abstract: Aspergillus is a ubiquitous fungus that can cause a variety of clinical syndromes. It can lead to a spectrum of clinical presentations depending upon the severity of the disease, degree of immune compromisation, nature and intensity of inflammatory host ... ...

    Abstract Aspergillus is a ubiquitous fungus that can cause a variety of clinical syndromes. It can lead to a spectrum of clinical presentations depending upon the severity of the disease, degree of immune compromisation, nature and intensity of inflammatory host response. Ovarian aspergilloma is extremely unusual, only a few case reports have been described in the literature. Here, we report a case of ovarian aspergilloma which was masquerading as ovarian neoplasm on clinical examination and radiology. To the best of our knowledge, this is the first case report of isolated ovarian aspergillosis in an immunocompetent patient.
    Language English
    Publishing date 2023-03-27
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2788093-X
    ISSN 2360-6975 ; 2360-6975
    ISSN (online) 2360-6975
    ISSN 2360-6975
    DOI 10.22551/2023.38.1001.10237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Primary neuroendocrine carcinoma of cervical lymph node masquerading as non-Hodgkin lymphoma: A diagnostic challenge.

    Singh, Anurag / Kushwaha, Rashmi / Chauhan, Pragati / Kumar, Gulshan

    Journal of cancer research and therapeutics

    2023  

    Abstract: Abstract: A large extended family of tumors classified as neuroendocrine tumors most commonly occurs in the gastrointestinal tract and bronchus pulmonary tree. It is extremely unusual for a primary neuroendocrine tumor to present as a cervical lymph ... ...

    Abstract Abstract: A large extended family of tumors classified as neuroendocrine tumors most commonly occurs in the gastrointestinal tract and bronchus pulmonary tree. It is extremely unusual for a primary neuroendocrine tumor to present as a cervical lymph node mass at initial presentation. We discuss the rare case of a 55-year-old man who initially complained of a right neck mass that was misinterpreted as non-Hodgkin lymphoma on fine needle aspiration cytology. By integrating clinical findings, radiography, fine-needle aspiration cytology, histomorphology, and immunohistochemistry analysis, a definitive diagnosis of primary neuroendocrine carcinoma of the cervical lymph node was made. He received chemotherapy and decompressive radiation as treatment. Regarding the course of disease in the present case, the patients underwent a distant subcutaneous metastasis over the right anterior chest wall 10 months after the initial manifestation. The patient is still alive, albeit his general condition has gotten deteriorated, and he is getting regular follow-ups.
    Language English
    Publishing date 2023-12-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.jcrt_2572_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Optimization of Low-Tech Protected Structure and Irrigation Regime for Cucumber Production under Hot Arid Regions of India.

    Kumar, Pradeep / Khapte, Pratapsingh S / Singh, Akath / Saxena, Anurag

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 1

    Abstract: Water scarcity and climate variability impede the realization of satisfactory vegetable yields in arid regions. It is imperative to delve into high-productivity and water-use-efficient protected cultivation systems for the sustained supply of vegetables ... ...

    Abstract Water scarcity and climate variability impede the realization of satisfactory vegetable yields in arid regions. It is imperative to delve into high-productivity and water-use-efficient protected cultivation systems for the sustained supply of vegetables in harsh arid climates. A strenuous effort was made to find suitable protected structures and levels of irrigation for greenhouse cucumber production in hot arid zones of India. In this endeavor, the effects of three low-tech passively ventilated protected structures, i.e., naturally ventilated polyhouse (NVP), insect-proof screenhouse (IPS) and shade screenhouse (SHS), as well as three levels of irrigation (100%, 80% and 60% of evapotranspiration, ET) were assessed for different morpho-physiological, yield and quality traits of the cucumber in a two-year study. Among the low-tech protected structures, NVP was found superior to IPS and SHS for cucumber performance, as evidenced by distinctly higher fruit yields (i.e., 31% and 121%, respectively) arising as a result of higher fruit number/plants and mean fruit weights under NVP. The fruit yield decreased in response to the degree of water shortage in deficit irrigation across all protected structures. However, the interaction effect of the protected structure and irrigation regime reveals that plants grown under moderate deficit (MD, 20% deficit) inside NVP could provide higher yields than those obtained under well-watered (WW, 100% of ET) conditions inside IPS or SHS. Plant growth indices such as vine length, node number/plant, and shoot dry mass were also measured higher under NVP. The greater performance of cucumber under NVP was attributed to a better plant physiological status (i.e., higher photosystem II efficiency, leaf relative water content and lower leaf water potential). The water deficit increased water productivity progressively with its severity; it remained higher in NVP, as reflected by 20% and 94% higher water productivity than those recorded in IPS and SHS, respectively, across different irrigation levels. With the exception of total soluble solids and fruit dry matter content (which were recorded higher), fruit quality parameters were reduced under water deficit conditions. The findings of this study emphasize the importance of considering suitable low-tech protected structures (i.e., NVP) and irrigation levels (i.e., normal rates for higher yields and moderate deficit (-20%) for satisfactory yields) for cucumber in hot arid regions. The results provide valuable insights for growers as well as researchers aiming to increase vegetable production under harsh climates and the water-limiting conditions of arid regions.
    Language English
    Publishing date 2024-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13010146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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