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  1. Article: Croup Is One of the Clinical Manifestations of Novel Coronavirus in Children.

    Kamali Aghdam, Mojtaba / Shabani Mirzaee, Hosein / Eftekhari, Kambiz

    Case reports in pulmonology

    2021  Volume 2021, Page(s) 8877182

    Abstract: The manifestations of novel coronavirus are diverse and can manifest through respiratory, gastrointestinal, and even nervous symptoms. Respiratory involvement is usually an upper tract infection or pneumonia but can also present as other forms of ... ...

    Abstract The manifestations of novel coronavirus are diverse and can manifest through respiratory, gastrointestinal, and even nervous symptoms. Respiratory involvement is usually an upper tract infection or pneumonia but can also present as other forms of pulmonary disorders. A 3-year-old boy presented with cough, hoarseness, and stridor. He was treated with dexamethasone and nebulized adrenaline and a clinical diagnosis of croup was established. After treatment, his symptoms improved for a short time, but suddenly cough exacerbated and was accompanied by respiratory failure and seizures. He was then intubated and mechanically ventilated. Because of the coronavirus epidemic, Reverse-Transcription Polymerase Chain Reaction (RT-PCR) assay was taken from the pharyngeal secretions and was positive. The child was isolated. Due to excessive respiratory secretions and worsening of the general condition, bronchoscopy was performed depicting an image compatible with bacterial tracheitis. He was treated with broad-spectrum antibiotics, antivirals, and supportive care. Finally, after 4 weeks of treatment, the child was discharged in good general condition. Croup is one of the respiratory symptoms of novel coronavirus and can be a risk factor for bacterial tracheitis. Therefore, the presence of clinical manifestations of croup indicates the need for coronavirus PCR testing.
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2666707-1
    ISSN 2090-6854 ; 2090-6846
    ISSN (online) 2090-6854
    ISSN 2090-6846
    DOI 10.1155/2021/8877182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report.

    Kamali Aghdam, Mojtaba / Jafari, Nahid / Eftekhari, Kambiz

    Infectious diseases (London, England)

    2020  Volume 52, Issue 6, Page(s) 427–429

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Humans ; Infant, Newborn ; Male ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sepsis/virology ; COVID-19 Drug Treatment
    Chemical Substances Anti-Bacterial Agents ; Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-04-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2839775-7
    ISSN 2374-4243 ; 2374-4235
    ISSN (online) 2374-4243
    ISSN 2374-4235
    DOI 10.1080/23744235.2020.1747634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report

    Kamali Aghdam, Mojtaba / Jafari, Nahid / Eftekhari, Kambiz

    Infect Dis (Lond)

    Abstract: Introduction: Novel coronavirus or coronavirus disease (COVID-19) can affect all age groups. The clinical course of the disease in children and infants is milder than in adults. It should be noted that, although typical symptoms may be present in ... ...

    Abstract Introduction: Novel coronavirus or coronavirus disease (COVID-19) can affect all age groups. The clinical course of the disease in children and infants is milder than in adults. It should be noted that, although typical symptoms may be present in children, non-specific symptoms could be noted in the neonate. The disease is rare in the neonate, so, its suspicion in this group can help to make a quick diagnose.Case report: A 15-day-old neonate was admitted with fever, lethargy, cutaneous mottling, and respiratory distress without cough. His mother had symptoms of Novel coronavirus. So Reverse-Transcription Polymerase Chain Reaction (RT-PCR) assay was done for the neonate and showed to be positive. The newborn was isolated and subjected to supportive care. Antibiotic and antiviral treatment was initiated. Eventually, the baby was discharged in good general condition.Conclusion: When a newborn presents with non-specific symptoms of infection with an added history of COVID-19 in his/her parents, it indicates the need for PCR testing for Novel coronavirus.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #23422
    Database COVID19

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  4. Article: Neurological Manifestations of Novel Coronavirus Disease in a 2-Month-Old Infant: A Case Report

    Kamali Aghdam, Mojtaba / Bakhtiari, Hassan / Diaz, Diana Noemi / Eftekhari, Kambiz

    Journal of Pediatric Neurology

    2020  Volume 19, Issue 03, Page(s) 210–212

    Abstract: The main manifestations of novel coronavirus usually include fever and cough. Neurological manifestations have not been properly identified in children. A 65-day-old infant was hospitalized due to poor feeding, weakness, lethargy, and occasional cough. ... ...

    Abstract The main manifestations of novel coronavirus usually include fever and cough. Neurological manifestations have not been properly identified in children. A 65-day-old infant was hospitalized due to poor feeding, weakness, lethargy, and occasional cough. She suffered several seizures during her hospitalization. The brain computed tomography scan depicted a minor hemorrhage. Due to the exacerbation of her condition during hospital stay and the presence of respiratory symptoms in her parents, coronavirus disease was suspected. Reverse transcription–polymerase chain reaction (PCR) of coronavirus was positive for both: child and parents. In children with neurological manifestations such as lethargy, recurrent seizures, cerebral hemorrhage, and clinical evidence of respiratory symptoms in his/her relatives, PCR testing for coronavirus is recommended.
    Keywords infants ; neurological symptoms ; novel coronavirus
    Language English
    Publishing date 2020-09-02
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 1875-9041 ; 1304-2580
    ISSN (online) 1875-9041
    ISSN 1304-2580
    DOI 10.1055/s-0040-1716393
    Database Thieme publisher's database

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  5. Article ; Online: Recurrent Epistaxis and Bleeding as the Initial Manifestation of Brucellosis.

    Kamali Aghdam, Mojtaba / Davari, Kambiz / Eftekhari, Kambiz

    Acta medica Iranica

    2016  Volume 54, Issue 3, Page(s) 218–219

    Abstract: Severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. Brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. ... ...

    Abstract Severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. Brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. Bone marrow aspiration (BMA) is mandatory to differentiate from other blood diseases. An 8-year-old boy was admitted with recurrent epistaxis, petechiae and purpura on face and extremities and bleeding from the gums. During the hospitalization, he was febrile and complained of muscle pain. Leukopenias associated with thrombocytopenia were observed. BMA showed to be normal. Among the multiple tests requested, only serum agglutination test (SAT) and 2-MercaptoEthanol test (2-ME) were positive. He was treated with Intravenous immunoglobulin (IVIG) associated with co-trimoxazole and rifampin. Finally, fever subsided, and he was discharged with good condition and normal platelet count. Brucellosis should be a differential diagnosis in patients with fever and bleeding disorders and a history of consumption of unpasteurized dairy, in endemic areas.
    MeSH term(s) Agglutination Tests ; Brucellosis/complications ; Brucellosis/diagnosis ; Child ; Diagnosis, Differential ; Epistaxis/etiology ; Fever/etiology ; Humans ; Male ; Thrombocytopenia/etiology
    Language English
    Publishing date 2016-03
    Publishing country Iran
    Document type Case Reports ; Journal Article
    ZDB-ID 603042-7
    ISSN 1735-9694 ; 0044-6025
    ISSN (online) 1735-9694
    ISSN 0044-6025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Clinical and Epidemiologic Findings of Pertussis Suspected Patients Referred to Zanjan Health Centers in 2011-2012

    Mojtaba Kamali Aghdam / Alinaghi Kazemi / Farmehr Elmi / Mansour Sadeghzadeh

    Bihdād, Vol 7, Iss 4, Pp 293-

    2018  Volume 298

    Abstract: Introduction: Despite frequent vaccination, Pertussis is still relatively common in the world. The prevalence of this disease has been reported differently in different parts of the world. The aim of this study was to investigate clinical and pediatric ... ...

    Abstract Introduction: Despite frequent vaccination, Pertussis is still relatively common in the world. The prevalence of this disease has been reported differently in different parts of the world. The aim of this study was to investigate clinical and pediatric findings and compare them with the results of nasopharyngeal culture in suspected Pertussis patients in Zanjan province. Materials and Methods: In this cross-sectional study, records of all patients referred to Zanjan health center during 2011-2015 with suspected Pertussis were evaluated. Data were collected from questionnaires and analyzed by SPSS v16 software using frequency distribution, chi-square and chi-square test. Findings: Of the 243 patients examined, 17 (7%) patients were positive for nasopharyngeal culture. Eight of them were male and 9 were females. The highest number of cases was in winter (9 cases). We found cough in all cases and post coughing vomiting in 15 cases . Of the 17 positive cultured patients, 11 patients were below 6 months (before completing three doses of vaccine). Discussion & Conclusion: In this study, the positive nasopharyngeal culture was similar to most of the national’s studies but was less than that of other countries.
    Keywords Pertussis ; positive culture of nasopharynx ; Zanjan ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 610
    Language Persian
    Publishing date 2018-12-01T00:00:00Z
    Publisher Alborz University of Medical Sciencs
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Recurrent Epistaxis and Bleeding as the Initial Manifestation of Brucellosis

    Mojtaba Kamali Aghdam / Kambiz Davari / Kambiz Eftekhari

    Acta Medica Iranica, Vol 54, Iss

    2016  Volume 3

    Abstract: Severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. Brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. ... ...

    Abstract Severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. Brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. Bone marrow aspiration (BMA) is mandatory to differentiate from other blood diseases. An 8-year-old boy was admitted with recurrent epistaxis, petechiae and purpura on face and extremities and bleeding from the gums. During the hospitalization, he was febrile and complained of muscle pain. Leukopenias associated with thrombocytopenia were observed. BMA showed to be normal. Among the multiple tests requested, only serum agglutination test (SAT) and 2-MercaptoEthanol test (2-ME) were positive. He was treated with Intravenous immunoglobulin (IVIG) associated with co-trimoxazole and rifampin. Finally, fever subsided, and he was discharged with good condition and normal platelet count. Brucellosis should be a differential diagnosis in patients with fever and bleeding disorders and a history of consumption of unpasteurized dairy, in endemic areas.
    Keywords Brucellosis ; Epistaxis ; Severe thrombocytopenia ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2016-04-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: A Randomized Double-Blind Placebo-Controlled Trial of Lactobacillus reuteri for Chronic Functional Abdominal Pain in Children.

    Eftekhari, Kambiz / Vahedi, Zahra / Kamali Aghdam, Mojtaba / Noemi Diaz, Diana

    Iranian journal of pediatrics

    2015  Volume 25, Issue 6, Page(s) e2616

    Abstract: Background: Functional abdominal pain (FAP) is one of the most common diseases, and large percentages of children suffer from it.: Objectives: The purpose of the study was to evaluate the effect of Lactobacillus reuteri in treatment of children with ... ...

    Abstract Background: Functional abdominal pain (FAP) is one of the most common diseases, and large percentages of children suffer from it.
    Objectives: The purpose of the study was to evaluate the effect of Lactobacillus reuteri in treatment of children with functional abdominal pain.
    Patients and methods: This study was a randomized double-blind placebo-controlled trial. Children aged 4 to 16 years with chronic functional abdominal pain (based on Rome III criteria) were enrolled in the study. They were randomly divided into two groups, one receiving probiotic and the other placebo.
    Results: Forty children received probiotic and forty others placebo. There were no significant differences in age, weight, sex, location of pain, associated symptoms, frequency and intensity of pain between the groups. The severity and frequency of abdominal pain in the first month compared to baseline was significantly less and at the end of the second month, there was no significant difference between both groups compared to the end of the first month.
    Conclusions: This study showed that the severity of pain was significantly reduced in both groups. There was no significant difference in pain scores between them. The effect of probiotic and placebo can probably be attributed to psychological effect of the drugs.
    Language English
    Publishing date 2015-12-23
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2388780-1
    ISSN 2008-2150 ; 2008-2142
    ISSN (online) 2008-2150
    ISSN 2008-2142
    DOI 10.5812/ijp.2616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: High frequency of vancomycin-resistant enterococcus faecalis in an Iranian referral children medical hospital.

    Pourakbari, Babak / Aghdam, Mojtaba Kamali / Mahmoudi, Shima / Ashtiani, Mohammad Taghi Haghi / Sabouni, Farah / Movahedi, Zahra / Alyari, Amir Esmael / Sadeghi, Reihane Hosseinpour / Mamishi, Setareh

    Maedica

    2013  Volume 7, Issue 3, Page(s) 201–204

    Abstract: Background: Enterococci have emerged in recent years as important nosocomial pathogens. Although most enterococcal human infections are caused by Enterococcus faecalis, studies on vancomycin resistance are usually limited to Enterococcus faecium ... ...

    Abstract Background: Enterococci have emerged in recent years as important nosocomial pathogens. Although most enterococcal human infections are caused by Enterococcus faecalis, studies on vancomycin resistance are usually limited to Enterococcus faecium isolates and a little is known about E. faecalis. Therefore we undertook this study to obtain information about the prevalence of vancomycin -resistant E. faecalis (VREF) and genes responsible for resistance.
    Material and methods: Ninety-one E. faecalis isolates of different patients admitted at Children's Medical Center from August 2009 to June 2010 were included in this cross-sectional study. Antimicrobial testing was performed by Kirby-Bauer disk diffusion method according to Clinical Laboratories Standards Institute (CLSI).
    Results: Among all isolates, 15 (16%) were identified as VR E. faecalis. PCR analysis revealed that all VREF isolates were positive for the vanA gene.
    Conclusion: The present study reports the highest range of VREF in Iran. The increased frequency of VREF, as seen with rapid rise in the number of VanA isolates should be considered in infection control practices.
    Language English
    Publishing date 2013-02-08
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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