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  1. Article ; Online: A randomized and controlled multicenter prospective study of the Chinese medicinal compound Fufang Xuelian Burn Ointment for the treatment of superficial and deep second-degree burn wounds.

    Ouyang, Jing / Chen, Yong-chuan / Luo, Gao-xing / Yan, Hong / Peng, Yi-zhi / Huang, Yue-sheng / Xia, Pei-yuan / Zhang, Qin / Liao, Zhen-jiang / Li, Guo-hui / Yang, Xiao-dong / Cai, Yong-qing

    Cell biochemistry and biophysics

    2014  Volume 69, Issue 3, Page(s) 467–474

    Abstract: ... of a traditional Chinese medicine, Fufang Xuelian Burn Ointment (FXBO), to treat superficial and deep second-degree burn wounds ...

    Abstract The objective of this study was to evaluate the efficacy and safety of a traditional Chinese medicine, Fufang Xuelian Burn Ointment (FXBO), to treat superficial and deep second-degree burn wounds. A four-center, randomized, controlled, and prospective study was conducted. Overall, 240 patients with either superficial or deep second-degree burn wounds were enrolled consecutively in this study. Patients who were randomly assigned to the control group (superficial: 72, deep: 48) underwent common burn wound therapy, whereas those randomized to the treatment group (superficial: 72, deep: 48) received common burn wound therapy plus topical FXBO. The healing rate, healing time, effective rate, and safety data were compared between the two groups. The baseline characteristics were comparable for the two groups. The healing rate was 94.79(±7.50) in the control group and 98.60(±5.69) in the FXBO group after 14 days for patients with superficial second-degree burn wounds (P = 0.000), and 95.17(±9.68) versus 97.44(±9.81) at 28 for deep second-degree burn wounds (P = 0.025). The median healing time in the FXBO group were 9 and 21 days for superficial and deep second-degree burns, respectively, compared to 10.5 and 22.5 days, respectively, in control group (P(superficial) = 0.000 and P(deep) = 0.009). The results of the effective rate showed that comprehensive efficacy of the FXBO group was improved compared to the control group for either superficial or deep second-degree burns (P(superficial) = 0.035 and P deep = 0.003). There were no reported drug-related adverse events in both groups. Therefore, FXBO was well tolerated and more effective than control group for treating superficial and deep second-degree burn wounds.
    MeSH term(s) Adolescent ; Adult ; Aged ; Burns/drug therapy ; Burns/physiopathology ; Drugs, Chinese Herbal/adverse effects ; Drugs, Chinese Herbal/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Ointments ; Prospective Studies ; Safety ; Treatment Outcome ; Wound Healing/drug effects ; Young Adult
    Chemical Substances Drugs, Chinese Herbal ; Ointments ; fufang xuelian
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1357904-6
    ISSN 1559-0283 ; 1085-9195
    ISSN (online) 1559-0283
    ISSN 1085-9195
    DOI 10.1007/s12013-014-9819-5
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    Zs.A 1498: Show issues Location:
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  2. Article ; Online: Efficacy of Xuebijing Injection for Sepsis (EXIT-SEP): Lost in Translation.

    Liao, Xuelian / Rello, Jordi

    Anaesthesia, critical care & pain medicine

    2023  Volume 42, Issue 4, Page(s) 101257

    MeSH term(s) Humans ; Sepsis/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Injections
    Chemical Substances Xuebijing ; Drugs, Chinese Herbal
    Language English
    Publishing date 2023-06-01
    Publishing country France
    Document type Editorial ; Comment
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2023.101257
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  3. Article: Hypervirulent

    Chen, Junjun / Zhang, Huan / Liao, Xuelian

    Infection and drug resistance

    2023  Volume 16, Page(s) 5243–5249

    Abstract: ... ...

    Abstract Hypervirulent
    Language English
    Publishing date 2023-08-11
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2494856-1
    ISSN 1178-6973
    ISSN 1178-6973
    DOI 10.2147/IDR.S418523
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  4. Article ; Online: Patpat: a public proteomics dataset search framework.

    Liao, Weiheng / Zhang, Xuelian

    Bioinformatics (Oxford, England)

    2023  Volume 39, Issue 2

    Abstract: Summary: As the FAIR (Findable, Accessible, Interoperable, Reusable) principles have become widely accepted in the proteomics field, under the guidance of ProteomeXchange and The Human Proteome Organization Proteomics Standards Initiative, proteomics ... ...

    Abstract Summary: As the FAIR (Findable, Accessible, Interoperable, Reusable) principles have become widely accepted in the proteomics field, under the guidance of ProteomeXchange and The Human Proteome Organization Proteomics Standards Initiative, proteomics public databases have been providing Application Programming Interfaces for programmatic access. Based on generating logic from proteomics data, we present Patpat, an extensible framework for searching public datasets, merging results from multiple databases to help researchers find their proteins of interest in the vast mass spectrometry. Patpat's 2D strategy of combining results from multiple databases allows users to provide only protein identifiers to obtain metadata for relevant datasets, improving the 'Findable' of proteomics data.
    Availability and implementation: The Patpat framework is released under the Apache 2.0 license open source, and the source code is stored on GitHub (https://github.com/henry-leo/Patpat) and is freely available.
    Supplementary information: Supplementary data are available at Bioinformatics online.
    MeSH term(s) Humans ; Proteomics/methods ; Software ; Mass Spectrometry ; Proteome/metabolism ; Metadata
    Chemical Substances Proteome
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1422668-6
    ISSN 1367-4811 ; 1367-4803
    ISSN (online) 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btad076
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  5. Article ; Online: Takotsubo cardiomyopathy following pericardiectomy: A case report.

    Zhang, Huan / Liao, Xuelian

    Journal of cardiac surgery

    2021  Volume 36, Issue 11, Page(s) 4413–4415

    Abstract: Background: Takotsubo cardiomyopathy (TC) is defined as a temporary and reversible systolic abnormality of the left ventricle's apical area resembling myocardial infarction in the nonexistence of coronary artery disease. Only a few cases have been ... ...

    Abstract Background: Takotsubo cardiomyopathy (TC) is defined as a temporary and reversible systolic abnormality of the left ventricle's apical area resembling myocardial infarction in the nonexistence of coronary artery disease. Only a few cases have been reported after cardiac operations or after pericardiocentesis.
    Aim: To emphasize the need to be aware of the possibility of the occurrence of this potentially fatal complication after cardiac surgery.
    Materials and methods: A 66-year-old man underwent a pericardiectomy. He progressed to exacerbation of hemodynamic instability postoperatively and was diagnosed with TC, finally, he had to be supported by an intra-aortic balloon pump (IABP), extracorporeal membrane oxygenation (ECMO).
    Results: Patient's left ventricle function recovered fully in 2 weeks.
    Discussion: We discussed the pathogenesis and treatment of postoperative TC.
    Conclusion: TC has to be carefully considered in the differential diagnosis in case of acute left ventricle dysfunction following cardiac surgery.
    MeSH term(s) Aged ; Humans ; Intra-Aortic Balloon Pumping ; Male ; Myocardial Infarction ; Pericardiectomy ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/etiology ; Takotsubo Cardiomyopathy/therapy ; Ventricular Function, Left
    Language English
    Publishing date 2021-08-29
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.15948
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    Zs.A 2221: Show issues Location:
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  6. Article: Biocontrol ability of

    Liao, Jie / Liang, Xuelian / Li, Huiling / Mo, Leixing / Mo, Renfu / Chen, Wei / Wei, Yuning / Wang, Tianshun / Jiang, Wenyan

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1314887

    Abstract: Sugarcane ( ...

    Abstract Sugarcane (
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1314887
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  7. Article ; Online: Interactions Between Astrocytes and Oligodendroglia in Myelin Development and Related Brain Diseases.

    Hu, Xuelian / Yu, Guangdan / Liao, Xiang / Xiao, Lan

    Neuroscience bulletin

    2022  Volume 39, Issue 3, Page(s) 541–552

    Abstract: Astrocytes (ASTs) and oligodendroglial lineage cells (OLGs) are major macroglial cells in the central nervous system. ASTs communicate with each other through connexin (Cx) and Cx-based network structures, both of which allow for quick transport of ... ...

    Abstract Astrocytes (ASTs) and oligodendroglial lineage cells (OLGs) are major macroglial cells in the central nervous system. ASTs communicate with each other through connexin (Cx) and Cx-based network structures, both of which allow for quick transport of nutrients and signals. Moreover, ASTs interact with OLGs through connexin (Cx)-mediated networks to modulate various physiological processes in the brain. In this article, following a brief description of the infrastructural basis of the glial networks and exocrine factors by which ASTs and OLGs may crosstalk, we focus on recapitulating how the interactions between these two types of glial cells modulate myelination, and how the AST-OLG interactions are involved in protecting the integrity of the blood-brain barrier (BBB) and regulating synaptogenesis and neural activity. Recent studies further suggest that AST-OLG interactions are associated with myelin-related diseases, such as multiple sclerosis. A better understanding of the regulatory mechanisms underlying AST-OLG interactions may inspire the development of novel therapeutic strategies for related brain diseases.
    MeSH term(s) Humans ; Myelin Sheath ; Astrocytes ; Oligodendroglia ; Brain ; Brain Diseases
    Language English
    Publishing date 2022-11-12
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2419741-5
    ISSN 1995-8218 ; 1673-7067
    ISSN (online) 1995-8218
    ISSN 1673-7067
    DOI 10.1007/s12264-022-00981-z
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  8. Article ; Online: Female representation in intensive care medicine: Challenges and perspectives from China.

    Liao, Xuelian / Yang, Yi / Francesca, Rubulotta / Kang, Yan / Rello, Jordi

    Journal of intensive medicine

    2022  Volume 2, Issue 2, Page(s) 89–91

    Abstract: The gender gap in the practice of intensive care medicine has increasingly been recognized as a problem in recent years. Despite limited information, the available data suggest that representation of women in the physician workforce, academic positions, ... ...

    Abstract The gender gap in the practice of intensive care medicine has increasingly been recognized as a problem in recent years. Despite limited information, the available data suggest that representation of women in the physician workforce, academic positions, and leadership roles in intensive care is inadequate globally. In this article, we describe the situation of female intensive care unit (ICU) physicians from the perspective of Chinese intensivists. The proportion of female ICU physicians in China has been increasing in recent years. The biggest challenges faced by female ICU physicians include balance of work and life, difficulties in career planning, and lack of academic influence. More attention and policy support should be provided to help them play a better role in intensive care medicine.
    Language English
    Publishing date 2022-01-07
    Publishing country China
    Document type Journal Article
    ISSN 2667-100X
    ISSN (online) 2667-100X
    DOI 10.1016/j.jointm.2021.12.002
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  9. Article ; Online: Penetrating canaloplasty in angle-closure glaucoma secondary to iridocorneal endothelial syndrome following multiple failed filtering surgeries: A case report.

    Tian, Xuelian / Guo, Juan / Liao, Jinying / He, Meng / Shi, Yinwen / Tang, Li

    Medicine

    2023  Volume 102, Issue 8, Page(s) e32950

    Abstract: Rationale: Angle-closure glaucoma secondary to iridocorneal endothelial syndrome (ICE) is challenging to treat, especially in patients who have already undergone multiple surgical procedures. Long-term success is difficult to achieve with traditional ... ...

    Abstract Rationale: Angle-closure glaucoma secondary to iridocorneal endothelial syndrome (ICE) is challenging to treat, especially in patients who have already undergone multiple surgical procedures. Long-term success is difficult to achieve with traditional filtration surgery again. This case report describes a novel nonbleb-dependent surgery for managing such a young patient.
    Patient concerns: A 30-year-old male with glaucoma secondary to ICE was referred to West China Hospital, Sichuan University for uncontrolled intraocular pressure following multiple failed filtering surgeries under maximum topical antiglaucoma medications in his right eye.
    Diagnoses: The patient was diagnosed with angle-closure glaucoma secondary to ICE in the right eye based on a series of ophthalmic examinations.
    Interventions: Penetrating canaloplasty was performed to manage glaucoma secondary to ICE in the right eye.
    Outcomes: The patient's visual acuity improved, the intraocular pressure was reduced to 11 to 15 mm Hg through 30 months of follow-up, and no antiglaucoma medication or additional surgical procedures were needed.
    Lessons: Penetrating canaloplasty could be considered as an option for the treatment of refractory angle-closure glaucoma secondary to ICE with extensive angle adhesion.
    MeSH term(s) Male ; Humans ; Adult ; Iridocorneal Endothelial Syndrome/complications ; Iridocorneal Endothelial Syndrome/surgery ; Glaucoma, Angle-Closure/complications ; Glaucoma/surgery ; Filtering Surgery/adverse effects ; Intraocular Pressure ; Treatment Outcome
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000032950
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  10. Article ; Online: Strengthening ICU health security for a coronavirus epidemic.

    Jansson, Miia / Liao, Xuelian / Rello, Jordi

    Intensive & critical care nursing

    2020  Volume 57, Page(s) 102812

    MeSH term(s) COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Critical Illness/therapy ; Health Behavior ; Humans ; Intensive Care Units/organization & administration ; Organizational Policy ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; Public Health Practice ; Security Measures/organization & administration
    Keywords covid19
    Language English
    Publishing date 2020-02-07
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2020.102812
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