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  1. Article ; Online: Risk stratification for diabetic eye screening. Reply to Stratton I. M. and Aldington S. J. [letter].

    Looker, H C / Nyangoma, S O / Cromie, D T / Olson, J A / Leese, G P / Philip, S / Black, M W / Doig, J / Lee, N / Briggs, A / Hothersall, E J / Morris, A D / Lindsay, R S / McKnight, J A / Pearson, D W M / Sattar, N A / Wild, S H / McKeigue, P / Colhoun, H M

    Diabetologia

    2013  Volume 57, Issue 1, Page(s) 260–261

    MeSH term(s) Diabetic Retinopathy/diagnosis ; Female ; Humans ; Male ; Mass Screening/methods
    Language English
    Publishing date 2013-11-08
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 1694-9
    ISSN 1432-0428 ; 0012-186X
    ISSN (online) 1432-0428
    ISSN 0012-186X
    DOI 10.1007/s00125-013-3099-2
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  2. Book ; Online ; E-Book: 3D printing at hospitals and medical centers

    Rybicki, Frank J. / Morris, Jonathan M. / Grant, Gerald T.

    a practical guide for medical professionals

    2024  

    Abstract: Zusammenfassung: This new edition describes the fundamentals of three-dimensional (3D) printing as applied to medicine and extends the scope of the first edition of 3D Printing in Medicine to include modern 3D printing within Health Care Facilities, also ...

    Institution SpringerLink (Online service)
    Author's details Frank J. Rybicki, Jonathan M. Morris, Gerald T. Grant editors
    Abstract Zusammenfassung: This new edition describes the fundamentals of three-dimensional (3D) printing as applied to medicine and extends the scope of the first edition of 3D Printing in Medicine to include modern 3D printing within Health Care Facilities, also called at the medical “Point-Of-Care” (POC). This edition addresses the practical considerations for, and scope of hospital 3D printing facilities, image segmentation and post-processing for Computer Aided Design (CAD) and 3D printing. The book provides details regarding technologies and materials for medical applications of 3D printing, as well as practical tips of value for physicians, engineers, and technologists. Individual, comprehensive chapters span all major organ systems that are 3D printed, including cardiovascular, musculoskeletal, craniomaxillofacial, spinal, neurological, thoracic, and abdominal. The fabrication of maxillofacial prosthetics, the planning of head and neck reconstructions, and 3D printed medical devices used in cranial reconstruction are also addressed. The second edition also includes guidelines and regulatory considerations, costs and reimbursement for medical 3D printing, quality assurance, and additional applications of CAD such as virtual reality. There is a new Forward written by Ron Kikinis, PhD and a new Afterword written by Michael W. Vannier, MD. This book offers radiologists, surgeons, and other physicians a rich source of information on the practicalities and expanding medical applications of 3D printing. It will also serve engineers, physicist, technologists, and hospital administrators who undertake 3D printing. The second edition is designed as a textbook and is expected to serve in this capacity to fill educational needs in both the medical and engineering sectors
    Keywords Radiology ; Surgery
    Subject code 616.075
    Language English
    Size Online-Ressource (x, 396 Seiten), Illustrationen, Diagramme
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030730239
    ISBN 978-3-031-42851-7 ; 9783031428500 ; 3-031-42851-X ; 3031428501
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Critique of "Sibpair studies implicate chromosome 18 in essential hypertension" by S. Rutherford, M.P. Johnson, and L.R. Griffiths. 2004. Am J Med Genet 126A:241-247.

    Morris, Brian J

    American journal of medical genetics. Part A

    2005  Volume 132A, Issue 4, Page(s) 456–7; author reply 458–60

    MeSH term(s) Chromosomes, Human, Pair 18/genetics ; Humans ; Hypertension/genetics ; Siblings
    Language English
    Publishing date 2005-01-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 2108614-X
    ISSN 1552-4825
    ISSN 1552-4825
    DOI 10.1002/ajmg.a.30476
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  4. Article: Comments to: P. Liësi, E.-M. Salonen, D. Dahl, A. Vaheri, and S.-J. Richards.

    Morris, R J

    Experimental brain research

    1990  Volume 82, Issue 2, Page(s) 459–461

    MeSH term(s) Animals ; Antigens, Surface/immunology ; Immunohistochemistry ; Nerve Tissue Proteins/immunology ; Neuroglia/immunology ; Plasminogen Activators/immunology ; Rats ; Thy-1 Antigens
    Chemical Substances Antigens, Surface ; Nerve Tissue Proteins ; Thy-1 Antigens ; Plasminogen Activators (EC 3.4.21.-)
    Language English
    Publishing date 1990
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/bf00231266
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  5. Article ; Online: Management of a stingray barb laceration and suspect envenomation in a dog.

    Milne, J M / Morris, Cad

    Australian veterinary journal

    2023  Volume 101, Issue 5, Page(s) 208–211

    Abstract: This case report describes the successful management of a stingray laceration and suspected envenomation using a combination of opioid analgesia, heat compression, antimicrobial therapy, surgical debridement and closure. Stingray envenomation in the dog ... ...

    Abstract This case report describes the successful management of a stingray laceration and suspected envenomation using a combination of opioid analgesia, heat compression, antimicrobial therapy, surgical debridement and closure. Stingray envenomation in the dog is a rare clinical presentation and is yet to be documented in the Australian veterinary literature. Envenomation can be markedly painful and may cause swelling and local tissue necrosis. No consensus on treatment guidelines has been published. Diagnostics and treatments performed are outlined with recommendations on a management plan for future cases.
    MeSH term(s) Dogs ; Animals ; Skates, Fish ; Lacerations/veterinary ; Bites and Stings/veterinary ; Australia ; Dog Diseases
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Case Reports
    ZDB-ID 41542-x
    ISSN 1751-0813 ; 0005-0423
    ISSN (online) 1751-0813
    ISSN 0005-0423
    DOI 10.1111/avj.13235
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  6. Article ; Online: Efficacy of Peracetic Acid and Sodium Hypochlorite against SARS-CoV-2 on Contaminated Surfaces.

    Morris, J N / Esseili, M A

    Applied and environmental microbiology

    2023  Volume 89, Issue 7, Page(s) e0062223

    Abstract: SARS-CoV-2 is primarily a respiratory virus that can potentially be transmitted through fomites. Sodium hypochlorite (NaOCl) and peracetic acid (PAA) are widely used disinfectants on surfaces in diverse settings such as hospitals and food production ... ...

    Abstract SARS-CoV-2 is primarily a respiratory virus that can potentially be transmitted through fomites. Sodium hypochlorite (NaOCl) and peracetic acid (PAA) are widely used disinfectants on surfaces in diverse settings such as hospitals and food production facilities. The objectives of this study were to investigate the virucidal efficacy of NaOCl and PAA against SARS-CoV-2 using the ASTM standard methods. In the suspension assay, NaOCl and PAA (5, 50, and 200 ppm) were tested against SARS-CoV-2 in the presence/absence of soil load after 1 min of contact time. In the carrier assay, NaOCl and PAA were tested at 200, 400, 600, and 1,000 ppm for 1 min and 200 and 1,000 ppm for 5 and 10 min. Stainless steel (SS) and high-density polyethylene (HDPE) disks were used as carriers. The virus was suspended in soil load and the disinfectants were prepared in 300 ppm of hard water. Virus quantification was done by TCID50 assay using Vero-E6 cell line. NaOCl and PAA were effective (> 3 log reduction in infectious virus) at 50 ppm in the absence of soil load. However, in the presence of soil load, 200 ppm was required for > 3 log reduction in virus infectivity. In contrast, NaOCl and PAA at 200 ppm and with a 1-min contact time were not effective against SARS-CoV-2 on either SS or HDPE surfaces. PAA at 200 ppm for 10 min was effective against SARS-CoV-2 on SS and HDPE surfaces, whereas NaOCl required 1,000 ppm for 10 min to be effective against SARS-CoV-2 on both surfaces.
    MeSH term(s) Humans ; Sodium Hypochlorite/pharmacology ; Peracetic Acid/pharmacology ; SARS-CoV-2 ; Pandemics ; Polyethylene ; COVID-19 ; Disinfectants/pharmacology
    Chemical Substances Sodium Hypochlorite (DY38VHM5OD) ; Peracetic Acid (I6KPI2E1HD) ; Polyethylene (9002-88-4) ; Disinfectants
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.00622-23
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  7. Article ; Online: Laryngeal Dysfunction Manifesting as Chronic Refractory Cough and Dyspnea: Laryngeal Physiology in Respiratory Health and Disease.

    Sundar, Krishna M / Stark, Amanda / Morris, Michael J

    Chest

    2024  

    Abstract: Topic importance: Laryngeal dysfunction as a cause of chronic refractory cough (CRC) and episodic dyspnea is often missed, which results in unnecessary testing and delays in diagnosis. Understanding laryngeal roles in breathing and airway protection can ...

    Abstract Topic importance: Laryngeal dysfunction as a cause of chronic refractory cough (CRC) and episodic dyspnea is often missed, which results in unnecessary testing and delays in diagnosis. Understanding laryngeal roles in breathing and airway protection can help to appreciate the propensity to laryngeal dysfunction with aging, chronic lung disease, and sleep apnea.
    Review findings: The human larynx is a complex muscular structure that is responsible for multiple roles of breathing, vocalization, coughing, and swallowing. To undertake these activities, the larynx has a high density of sensory and motor innervation. In addition to common embryological origins with the pharynx and esophagus, with which many laryngeal activities are shared, somatomotor and autonomic pathways regulate emotional, cognitive, and complex motor sequence-planning activities within the larynx. Due to its unique location, the larynx is susceptible to infectious and gastroesophageal reflux-related insults. Couple this with key roles in regulation of airflow and mediation of airway protective reflexes, it is not surprising that neuropathic abnormalities and muscle dysfunction frequently develop. The expression of laryngeal dysfunction as hypersensitivity to mechanical, thermal, chemical, and other stimuli leads to exaggerated airway protective reflexes (laryngeal adductor reflex and cough reflex) manifesting as dyspnea and cough.
    Summary: Pulmonologists should incorporate assessment of laryngeal dysfunction during evaluation of CRC and dyspnea. Recognition of laryngeal hypersensitivity in patient with CRC can identify patients who may benefit from cough suppression therapies. Similarly, timely identification of inducible laryngeal obstruction may not only resolve episodic dyspnea but lessen the need for unnecessary testing and treatments.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2024.03.026
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  8. Article ; Online: Evaluating Provider and Pharmacy Discordance in Potential Calcium Channel Blocker-Loop Diuretic Prescribing Cascade.

    Ndai, Asinamai M / Morris, Earl J / Winterstein, Almut G / Vouri, Scott M

    Drugs & aging

    2024  Volume 41, Issue 2, Page(s) 177–186

    Abstract: Background: Prescribing cascades occur when a drug-induced adverse event is treated with a new medication. Identifying clinical scenarios in which prescribing cascades are more likely to occur may help determine ways to prevent prescribing cascades.: ... ...

    Abstract Background: Prescribing cascades occur when a drug-induced adverse event is treated with a new medication. Identifying clinical scenarios in which prescribing cascades are more likely to occur may help determine ways to prevent prescribing cascades.
    Objective: To understand the extent to which discordant providers and discordant pharmacies contribute to the dihydropyridine calcium channel blocker (DH CCB)-loop diuretic prescribing cascade.
    Study population and design: A retrospective cohort study using Medicare Fee-For-Service data (2011-2018) of adults aged ≥ 66 years.
    Exposures: Patients who initiated DH CCB with subsequent initiation of loop diuretic (DH CCB-loop diuretic dyad) within 90 days or patients who initiated angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) with subsequent initiation of a loop diuretic (ACEI/ARB-loop diuretic dyad; control).
    Main outcomes: The primary outcomes were provider and pharmacy discordance for prescribing cascades and control drug pairs. Baseline clinical and socio-demographic characteristics were balanced using inverse probability of treatment weighting with propensity scores.
    Results:  Overall, we identified 1987 DH CCB-loop diuretic dyads and 3148 ACEI/ARB-loop diuretic dyads. Discordant providers occurred in 64% of DH CCB-loop diuretic dyads and 55% of ACEI/ARB-loop diuretic dyads, while discordant pharmacies occurred in 19% of DH CCB-loop diuretic dyads and 16% of ACEI/ARB-loop diuretic dyads. After adjustment, the risk of having discordant providers was 20% {Relative Risk (RR) 1.20 [95% confidence interval (CI), 1.14-1.26]} higher in the DH CCB-loop diuretic dyad compared with the ACEI/ARB-loop diuretic dyad. Moreover, pharmacy discordance was 17% (RR 1.17 [95% CI 1.02-1.33]) higher.
    Conclusion: Our findings suggest that discordant providers and discordant pharmacies were more commonly involved in the potential prescribing cascade when compared with a similar control dyad of medications. Opportunities for enhanced care coordination and medication reconciliation should be explored to prevent unnecessary polypharmacy.
    MeSH term(s) Humans ; Aged ; United States ; Calcium Channel Blockers/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Sodium Potassium Chloride Symporter Inhibitors/therapeutic use ; Hypertension/drug therapy ; Retrospective Studies ; Pharmacies ; Angiotensin Receptor Antagonists/therapeutic use ; Medicare ; Pharmacy
    Chemical Substances Calcium Channel Blockers ; Angiotensin-Converting Enzyme Inhibitors ; Sodium Potassium Chloride Symporter Inhibitors ; Angiotensin Receptor Antagonists
    Language English
    Publishing date 2024-01-22
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1075770-3
    ISSN 1179-1969 ; 1170-229X
    ISSN (online) 1179-1969
    ISSN 1170-229X
    DOI 10.1007/s40266-023-01091-9
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  9. Article ; Online: Response to letter to the editor: Lost in Transition.

    Preston, M / Morris, A / Villegas, R / Huston, J / Heloury, Y / Grover, S R

    Journal of pediatric urology

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Letter
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2024.02.020
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  10. Article ; Online: The impact of having a carer on adult health and social care utilisation across five settings of care: A matched cohort study.

    Shand, J / Gomes, M / Morris, S

    Health policy (Amsterdam, Netherlands)

    2023  Volume 129, Page(s) 104705

    Abstract: Introduction: An estimated 6.8 million people are (informal) carers in the UK. The economic value of annual carer contributions is an estimated .·132bn. Reliance on carers appears to be increasing. There is mixed evidence on whether carers are ... ...

    Abstract Introduction: An estimated 6.8 million people are (informal) carers in the UK. The economic value of annual carer contributions is an estimated .·132bn. Reliance on carers appears to be increasing. There is mixed evidence on whether carers are substitutes for formal care. This study investigated the association between having a carer and service use patterns across five care settings when compared to a matched cohort without a carer.
    Materials and methods: A matched case-control group analysis using person-level data in Barking and Dagenham (B&D), a London borough in the U.K., to assess the impact of having a carer in terms of the differences in cost-weighted utilisation relative to a matched control group.
    Results: In 2016/17, for adult residents of B&D, having a carer (n = 1,295) was associated with 27% increased cost-weighted utilisation (mean difference of £2,662, CI £1,595, £3,729, p<0.001) compared to a matched cohort without a carer. 39% of the cost difference was social care.
    Conclusions: Findings suggest additional service use induced by carers may dominate any substitution effect. Having a carer may be a key element in enabling access to services. As such, there may be wider inequalities in service access for people without a carer. For an ageing society with projections suggesting there will be more people without carers in the future, these inequalities need to be addressed.
    MeSH term(s) Humans ; Adult ; Caregivers ; Cohort Studies ; Social Support
    Language English
    Publishing date 2023-01-05
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605805-x
    ISSN 1872-6054 ; 0168-8510
    ISSN (online) 1872-6054
    ISSN 0168-8510
    DOI 10.1016/j.healthpol.2022.104705
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