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  1. Article ; Online: Conjunctivitis Preferred Practice Pattern.

    Cheung, Albert Y / Choi, Daniel S / Ahmad, Sumayya / Amescua, Guillermo / Jhanji, Vishal / Lin, Amy / Mian, Shahzad I / Rhee, Michelle K / Viriya, Elizabeth T / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P134–P204

    MeSH term(s) Humans ; Conjunctivitis/diagnosis ; Conjunctivitis, Bacterial
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.037
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  2. Article: Off-label use of paclitaxel and pembrolizumab in a case of platinum refractory epithelial ovarian cancer and extensive thromboembolism.

    Lam, Clarissa / Ha, Kristal / Hakam, Ardeshir / Shahzad, Mian M K

    Gynecologic oncology reports

    2022  Volume 41, Page(s) 100992

    Abstract: Management of platinum refractory ovarian cancer is challenging.•Extensive venous thromboembolism precludes anti-angiogenic combination chemotherapy.•Weekly paclitaxel and immune-checkpoint inhibitor combination provides a durable tumor control option. ...

    Abstract •Management of platinum refractory ovarian cancer is challenging.•Extensive venous thromboembolism precludes anti-angiogenic combination chemotherapy.•Weekly paclitaxel and immune-checkpoint inhibitor combination provides a durable tumor control option.
    Language English
    Publishing date 2022-05-02
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2818505-5
    ISSN 2352-5789
    ISSN 2352-5789
    DOI 10.1016/j.gore.2022.100992
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Corneal Edema and Opacification Preferred Practice Pattern®.

    Mian, Shahzad I / Viriya, Elizabeth T / Ahmad, Sumayya / Amescua, Guillermo / Cheung, Albert Y / Choi, Daniel S / Jhanji, Vishal / Lin, Amy / Rhee, Michelle K / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P247–P305

    MeSH term(s) Humans ; Corneal Edema/diagnosis ; Corneal Opacity
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.039
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  4. Article ; Online: Dry Eye Syndrome Preferred Practice Pattern®.

    Amescua, Guillermo / Ahmad, Sumayya / Cheung, Albert Y / Choi, Daniel S / Jhanji, Vishal / Lin, Amy / Mian, Shahzad I / Rhee, Michelle K / Viriya, Elizabeth T / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P1–P49

    MeSH term(s) Humans ; Dry Eye Syndromes/diagnosis ; Dry Eye Syndromes/therapy ; Ophthalmology ; Tears ; Sjogren's Syndrome
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Blepharitis Preferred Practice Pattern®.

    Lin, Amy / Ahmad, Sumayya / Amescua, Guillermo / Cheung, Albert Y / Choi, Daniel S / Jhanji, Vishal / Mian, Shahzad I / Rhee, Michelle K / Viriya, Elizabeth T / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P50–P86

    MeSH term(s) Humans ; Blepharitis/diagnosis ; Blepharitis/drug therapy ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corneal Ectasia Preferred Practice Pattern®.

    Jhanji, Vishal / Ahmad, Sumayya / Amescua, Guillermo / Cheung, Albert Y / Choi, Daniel S / Lin, Amy / Mian, Shahzad I / Rhee, Michelle K / Viriya, Elizabeth T / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P205–P246

    MeSH term(s) Humans ; Dilatation, Pathologic ; Corneal Diseases/diagnosis ; Cornea ; Corneal Topography ; Retrospective Studies ; Keratoconus/diagnosis
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bacterial Keratitis Preferred Practice Pattern®.

    Rhee, Michelle K / Ahmad, Sumayya / Amescua, Guillermo / Cheung, Albert Y / Choi, Daniel S / Jhanji, Vishal / Lin, Amy / Mian, Shahzad I / Viriya, Elizabeth T / Mah, Francis S / Varu, Divya M

    Ophthalmology

    2024  Volume 131, Issue 4, Page(s) P87–P133

    MeSH term(s) Humans ; Keratitis/diagnosis ; Keratitis/drug therapy ; Keratitis/microbiology ; Eye Infections, Bacterial/diagnosis ; Eye Infections, Bacterial/drug therapy ; Eye Infections, Bacterial/microbiology ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.12.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes

    Sharon E. Robertson / Maya Yasukawa / Douglas C. Marchion / Yin Xiong / Syeda Mahrukh Hussnain Naqvi / Tarik Gheit / Massimo Tommasino / Robert M. Wenham / Anna R. Giuliano / Johnathan M. Lancaster / Mian M. K. Shahzad

    PLoS ONE, Vol 18, Iss

    2023  Volume 12

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes.

    Robertson, Sharon E / Yasukawa, Maya / Marchion, Douglas C / Xiong, Yin / Naqvi, Syeda Mahrukh Hussnain / Gheit, Tarik / Tommasino, Massimo / Wenham, Robert M / Giuliano, Anna R / Lancaster, Johnathan M / Shahzad, Mian M K

    PloS one

    2023  Volume 18, Issue 12, Page(s) e0294448

    Abstract: Introduction: Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.: Objective: To explore the association between infectious agents and ovarian ... ...

    Abstract Introduction: Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.
    Objective: To explore the association between infectious agents and ovarian cancer, we investigated the prevalence of viral DNA in primary ovarian cancer tumors and its association with clinical outcomes.
    Methods: Archived tumors from 98 patients diagnosed with high-grade serous epithelial ovarian cancer were collected between 1/1/1994 and 12/31/2010. After DNA extraction, Luminex technology was utilized to identify polymerase chain reaction-amplified viral DNA for 113 specific viruses. Demographic data and disease characteristics were summarized using descriptive statistics. We used logistic regression and Cox proportional hazards model to assess associations between tumor viral status and disease outcome and between tumor viral presence and overall survival (OS), respectively.
    Results: Forty-six cases (45.9%) contained at least one virus. Six highly prevalent viruses were associated with clinical outcomes and considered viruses of interest (VOI; Epstein-Barr virus 1, Merkel cell polyomavirus, human herpes virus 6b, and human papillomaviruses 4, 16, and 23). Factors independently associated with OS were presence of VOI (HR 4.11, P = 0.0001) and platinum sensitivity (HR 0.21, P<0.0001). Median OS was significantly decreased when tumors showed VOI versus not having these viruses (22 vs 44 months, P<0.0001). Women <70 year old with VOI in tumors had significantly lower median OS versus age-matched women without VOI (20 vs 57 months, P = 0.0006); however, among women ≥70 years old, there was no difference in OS by tumor virus status.
    Conclusions: The presence of a VOI was significantly associated with a lower OS. These findings may have implications for clinical management of ovarian cancer but require additional studies.
    MeSH term(s) Humans ; Female ; Infant ; Aged ; Carcinoma, Ovarian Epithelial/epidemiology ; Carcinoma, Ovarian Epithelial/genetics ; DNA, Viral/genetics ; Prevalence ; Epstein-Barr Virus Infections ; Herpesvirus 4, Human/genetics ; Ovarian Neoplasms/epidemiology ; Ovarian Neoplasms/genetics ; Cystadenocarcinoma, Serous/pathology
    Chemical Substances DNA, Viral
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes.

    Sharon E Robertson / Maya Yasukawa / Douglas C Marchion / Yin Xiong / Syeda Mahrukh Hussnain Naqvi / Tarik Gheit / Massimo Tommasino / Robert M Wenham / Anna R Giuliano / Johnathan M Lancaster / Mian M K Shahzad

    PLoS ONE, Vol 18, Iss 12, p e

    2023  Volume 0294448

    Abstract: Introduction Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown. Objective To explore the association between infectious agents and ovarian cancer, ... ...

    Abstract Introduction Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown. Objective To explore the association between infectious agents and ovarian cancer, we investigated the prevalence of viral DNA in primary ovarian cancer tumors and its association with clinical outcomes. Methods Archived tumors from 98 patients diagnosed with high-grade serous epithelial ovarian cancer were collected between 1/1/1994 and 12/31/2010. After DNA extraction, Luminex technology was utilized to identify polymerase chain reaction-amplified viral DNA for 113 specific viruses. Demographic data and disease characteristics were summarized using descriptive statistics. We used logistic regression and Cox proportional hazards model to assess associations between tumor viral status and disease outcome and between tumor viral presence and overall survival (OS), respectively. Results Forty-six cases (45.9%) contained at least one virus. Six highly prevalent viruses were associated with clinical outcomes and considered viruses of interest (VOI; Epstein-Barr virus 1, Merkel cell polyomavirus, human herpes virus 6b, and human papillomaviruses 4, 16, and 23). Factors independently associated with OS were presence of VOI (HR 4.11, P = 0.0001) and platinum sensitivity (HR 0.21, P<0.0001). Median OS was significantly decreased when tumors showed VOI versus not having these viruses (22 vs 44 months, P<0.0001). Women <70 year old with VOI in tumors had significantly lower median OS versus age-matched women without VOI (20 vs 57 months, P = 0.0006); however, among women ≥70 years old, there was no difference in OS by tumor virus status. Conclusions The presence of a VOI was significantly associated with a lower OS. These findings may have implications for clinical management of ovarian cancer but require additional studies.
    Keywords Medicine ; R ; Science ; Q
    Subject code 616 ; 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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