LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 22

Search options

  1. Article: Adverse events associated with the gold probe and the injection gold probe devices used for endoscopic hemostasis: A MAUDE database analysis.

    Kumar, Vishnu Charan Suresh / Aloysius, Mark / Aswath, Ganesh

    World journal of gastrointestinal endoscopy

    2024  Volume 16, Issue 1, Page(s) 37–43

    Abstract: Background: Gastrointestinal (GI) bleeding accounts for over half a million admissions annually and is the most common GI diagnosis requiring hospitalization in the United States. Bipolar electrocoagulation devices are used for the management of ... ...

    Abstract Background: Gastrointestinal (GI) bleeding accounts for over half a million admissions annually and is the most common GI diagnosis requiring hospitalization in the United States. Bipolar electrocoagulation devices are used for the management of gastrointestinal bleeding. There is no data on device-related adverse events for gold probe (GP) and injection gold probe (IGP).
    Aim: To analyze this using the Food and Drug Administration (FDA's) Manufacturer and User Facility Device Experience (MAUDE) database from 2013 to 2023.
    Methods: We examined post-marketing surveillance data on GP and IGP from the FDA MAUDE database to report devicerelated and patient-related adverse events between 2013-2023. The MAUDE database is a publicly available resource providing over 4 million records relating to medical device safety. Statistical analyses were performed using IBM SPSS Statistics V.27.0 (IBM Corp., Armonk, NY, United States).
    Results: Our search elicited 140 reports for GP and 202 reports for IGP, respectively, during the study period from January 2013 to August 2023. Malfunctions reportedly occurred in 130 cases for GP, and actual patient injury or event occurred in 10 patients. A total of 149 patients (74%) reported with Injection GP events suffered no significant consequences due to the device failure, but 53 patients (26%) were affected by an event.
    Conclusion: GP and IGP are critical in managing gastrointestinal bleeding. This study of the FDA MAUDE database revealed the type, number, and trends of reported device-related adverse events. The endoscopist and support staff must be aware of these device-related events and be equipped to manage them if they occur.
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573698-X
    ISSN 1948-5190
    ISSN 1948-5190
    DOI 10.4253/wjge.v16.i1.37
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Fixation of Proximal flange of Lumen Apposing Metal Stent using Through-the-Scope Endoscopic Suturing System to Prevent Stent Migration in Single-Session EUS-directed Transgastric ERCP: A Pilot Study.

    Khan, Hafiz Muzaffar Akbar / Hussain, Azhar / Kumar, Vishnu Charan Suresh / Yang, Dennis / Hasan, Muhammad Khalid

    Gastrointestinal endoscopy

    2024  

    Abstract: Background and aims: With the global obesity pandemic, clinical scenarios requiring urgent ERCP in patients with gastric bypass surgery are on the rise and Single-Session Endoscopic Ultrasound-Directed Transgastric Endoscopic Retrograde ... ...

    Abstract Background and aims: With the global obesity pandemic, clinical scenarios requiring urgent ERCP in patients with gastric bypass surgery are on the rise and Single-Session Endoscopic Ultrasound-Directed Transgastric Endoscopic Retrograde Cholangiopancreatography (SS-EDGE) can effectively address these technical challenges. The aim of this study was to evaluate and describe safe and effective use of through-the-scope endoscopic suturing system for anchoring the lumen apposing metal stents (LAMS) during SS-EDGE.
    Methods: Six patients with Roux-en-Y gastric bypass (RYGB) underwent SS-EDGE at our center. Through-the-scope endoscopic suturing system was used for anchoring the lumen apposing metal stents (LAMS) during SS-EDGE.
    Results: Clinical and technical success was achieved in all six patients without any adverse events related to the procedure. No stent migration, pneumoperitoneum or gastrointestinal perforation noted. Upon 4 weeks follow-up, no stent migration was noted with Through-the-scope suturing system remained anchored. LAMS along with tacks were removed and gastric fistulae were successfully closed endoscopically in all patients to prevent weight gain.
    Conclusion: Use of through-the-scope endoscopic suturing can be a safe, reliable, and potentially cost-effective novel technique for LAMS fixation to successfully perform SS-EDGE in RYGB patients.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2024.02.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: The costly case of proton-pump inhibitors: a single-center experience.

    Suresh Kumar, Vishnu Charan / Patthipatti, Venkata Suresh / Mani, Kishore Kumar / Elangovan, Abbinaya / Goldstein, Lawrence

    Therapeutic advances in gastrointestinal endoscopy

    2020  Volume 13, Page(s) 2631774520919367

    Language English
    Publishing date 2020-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3011635-1
    ISSN 2631-7745 ; 2631-7745
    ISSN (online) 2631-7745
    ISSN 2631-7745
    DOI 10.1177/2631774520919367
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Syphilitic hepatitis as a manifestation of secondary syphilis.

    Subedi, Abinash / Hoilat, Gilles / Kumar, Vishnu Charan Suresh / Bhutta, Abdul / Subedi, Aakritee Sharma / Gupta, Anand

    Proceedings (Baylor University. Medical Center)

    2021  Volume 34, Issue 6, Page(s) 696–697

    Abstract: Syphilis is a multisystem disease caused by the ... ...

    Abstract Syphilis is a multisystem disease caused by the spirochete
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2021.1936362
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Persistent lactic acidosis in the Mauriac syndrome in type 1 diabetes mellitus.

    Subedi, Abinash / Kumar, Vishnu Charan Suresh / Sharma, Anuj / Hoilat, Gilles / John, Savio

    Proceedings (Baylor University. Medical Center)

    2021  Volume 34, Issue 3, Page(s) 382–383

    Abstract: Mauriac syndrome is an uncommon clinical condition arising in the setting of poorly controlled type 1 diabetes mellitus. Clinical features include hepatomegaly and liver abnormalities indistinguishable from nonalcoholic fatty liver disease. Early ... ...

    Abstract Mauriac syndrome is an uncommon clinical condition arising in the setting of poorly controlled type 1 diabetes mellitus. Clinical features include hepatomegaly and liver abnormalities indistinguishable from nonalcoholic fatty liver disease. Early diagnosis and management are essential, as Mauriac syndrome is reversible.
    Language English
    Publishing date 2021-01-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1866936
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: A Review of Hepatorenal Syndrome.

    Subedi, Abinash / Suresh Kumar, Vishnu Charan / Sharma Subedi, Aakritee / Sapkota, Bishnu

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16084

    Abstract: The development of acute kidney injury (AKI) is one of the most frequent complications in patients with cirrhosis. AKI due to volume depletion is the most common etiology and hepatorenal syndrome (HRS) is the second most common cause of AKI in these ... ...

    Abstract The development of acute kidney injury (AKI) is one of the most frequent complications in patients with cirrhosis. AKI due to volume depletion is the most common etiology and hepatorenal syndrome (HRS) is the second most common cause of AKI in these patients. HRS is the extreme form of kidney injury in patients with cirrhosis, which is caused due to a reduction in renal blood flow unresponsive to volume expansion.
    Language English
    Publishing date 2021-07-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16084
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Sex differences in clinical characteristics and outcomes associated with alcoholic hepatitis.

    Pemmasani, Gayatri / Tremaine, William J / Suresh Kumar, Vishnu Charan / Aswath, Ganesh / Sapkota, Bishnu / Karagozian, Raffi / John, Savio

    European journal of gastroenterology & hepatology

    2023  Volume 35, Issue 10, Page(s) 1192–1196

    Abstract: Background: Alcohol-associated liver disease is increasing among females with an earlier onset and more severe disease at lower levels of exposure. However, there is paucity of literature regarding sex differences related to alcoholic hepatitis.: ... ...

    Abstract Background: Alcohol-associated liver disease is increasing among females with an earlier onset and more severe disease at lower levels of exposure. However, there is paucity of literature regarding sex differences related to alcoholic hepatitis.
    Methods: Hospitalized patients with alcoholic hepatitis were selected from the US Nationwide readmissions database 2019. In this cohort, we evaluated sex differences in baseline comorbidities, alcoholic hepatitis related complications and mortality. A subset of patients with alcoholic hepatitis who were hospitalized between January and June 2019 were identified to study sex differences in 6 month readmission rate, mortality during readmission, and composite of mortality during index hospitalization or readmission.
    Results: Among 112 790 patients with alcoholic hepatitis, 33.3% were female. Female patients were younger [48 (38-57) vs. 49 (39-58) years; both P  < 0.001] but had higher rates of important medical and mental-health related comorbidities. Compared with males, females had higher rates of hepatic encephalopathy (11.5% vs. 10.1; P  < 0.001), ascites (27.9% vs. 22.5%; P  < 0.001), portal hypertension (18.5% vs. 16.4%; P  < 0.001), cirrhosis (37.3% vs. 31.9%; P  < 0.001), weight loss (19.0% vs. 14.5%; P  < 0.001), hepatorenal syndrome (4.4% vs. 3.8%; P  < 0.001), spontaneous bacterial peritonitis (1.9% vs. 1.7%; P  = 0.026), sepsis (11.1% vs. 9.5%; P  < 0.001), and blood transfusion (12.9% vs. 8.7%; P  < 0.001). Females had a similar in-hospital mortality rate (4.3%) compared to males (4.1%; P  = 0.202; adjusted odds ratio (OR) 1.02, 95% CI (cardiac index) 0.89-1.15; P  = 0.994). In the subset of patients ( N  = 58 688), females had a higher 6-month readmission rate (48.9% vs. 44.9%; adjusted OR 1.12 (1.06-1.18); P  < 0.001), mortality during readmission (4.4% vs. 3.2%; OR 1.23 (1.08-1.40); P  < 0.01), and composite of mortality during index hospitalization or readmission (8.7% vs. 7.2%; OR 1.15 (1.04-1.27); P  < 0.01).
    Conclusion: Compared to their male counterparts, females with alcoholic hepatitis were generally younger but had higher rates of comorbidities, alcoholic hepatitis related complications, rehospitalizations and associated mortality. The greater risks of alcohol-associated liver dysfunction in females indicate the need for more aggressive management.
    MeSH term(s) Humans ; Male ; Female ; Hepatitis, Alcoholic/diagnosis ; Hepatitis, Alcoholic/epidemiology ; Hepatitis, Alcoholic/therapy ; Sex Characteristics ; Retrospective Studies ; Hospitalization ; Liver Cirrhosis
    Language English
    Publishing date 2023-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034239-4
    ISSN 1473-5687 ; 0954-691X
    ISSN (online) 1473-5687
    ISSN 0954-691X
    DOI 10.1097/MEG.0000000000002612
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Epiploic Appendagitis: An Often Misdiagnosed Cause of Acute Abdomen.

    Suresh Kumar, Vishnu Charan / Mani, Kishore Kumar / Alwakkaa, Hisham / Shina, James

    Case reports in gastroenterology

    2019  Volume 13, Issue 3, Page(s) 364–368

    Abstract: Epiploic appendages are peritoneal structures that arise from the outer serosal surface of the bowel wall towards the peritoneal pouch. They are filled with adipose tissue and contain a vascular stalk. Epiploic appendagitis is a rare cause of acute lower ...

    Abstract Epiploic appendages are peritoneal structures that arise from the outer serosal surface of the bowel wall towards the peritoneal pouch. They are filled with adipose tissue and contain a vascular stalk. Epiploic appendagitis is a rare cause of acute lower abdominal pain. It most commonly results from torsion and inflammation of the epiploic appendages, and its clinical features mimic acute diverticulitis or acute appendicitis resulting in being often misdiagnosed as diverticulitis or appendicitis. This frequently leads to unnecessary hospitalization, antibiotic administration, and unwarranted surgeries. Epiploic appendagitis is usually diagnosed with CT imaging, and the classic CT findings include: (i) fat-density ovoid lesion (hyperattenuating ring sign), (ii) mild bowel wall thickening, and (iii) a central high-attenuation focus within the fatty lesion (central dot sign). It is treated conservatively, and symptoms typically resolve in a few days. Therefore, epiploic appendagitis should be considered as one of the differential diagnosis for acute lower abdominal pain and prompt diagnosis of epiploic appendagitis can avoid unnecessary hospitalization and surgical intervention. In this case report, we discuss a 72-year-old woman who presented with a 2-day history of acute left lower abdominal pain.
    Language English
    Publishing date 2019-09-05
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000502683
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: An integrative healthcare model with heartfulness meditation and care coordination improves outcomes in cyclic vomiting syndrome.

    Venkatesan, Thangam / Porcelli, Anthony / Matapurkar, Anagha / Suresh Kumar, Vishnu Charan / Szabo, Aniko / Yin, Ziyan / Wieloch, Laura

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2021  Volume 33, Issue 11, Page(s) e14132

    Abstract: Background: Cyclic vomiting syndrome (CVS) is associated with psychosocial comorbidity and often triggered by stress. Since the current disease-centered care model does not address psychosocial factors, we hypothesized that holistic, patient-centered ... ...

    Abstract Background: Cyclic vomiting syndrome (CVS) is associated with psychosocial comorbidity and often triggered by stress. Since the current disease-centered care model does not address psychosocial factors, we hypothesized that holistic, patient-centered care integrating meditation and addressing psychosocial needs through a care coordinator will improve healthcare outcomes in CVS.
    Methods: We conducted a prospective randomized controlled trial: 49 patients with CVS (mean age: 34 ± 14 years; 81% female) were randomized to conventional health care (controls) or Integrative Health care (IHC) (27: controls, 22: IHC). The IHC group was assigned a care coordinator and received meditation with a certified instructor. Outcomes including psychological distress, coping strategies to manage chronic stress, cognitive symptom management, and Health-Related Quality of Life (HRQoL) were measured.
    Key results: In intention-to-treat analyses, patients receiving IHC showed significant improvement in multiple domains of coping including positive reframing, planning, and reduction in self-blame (p values ≤0.05), and physical HRQoL (p = 0.03) at 6 months. They also leaned toward spirituality/religion as a coping measure (p ≤ 0.02 at 3 and 6 months). Subgroup analysis of compliant patients showed additional benefit with significant reduction in psychological distress (p = 0.04), improvement in sleep quality (p = 0.03), reduction in stress levels (0.02), improvement in physical HRQoL (0.04), and further improvement in other domains of coping (p < 0.05).
    Conclusions and inferences: An IHC model incorporating meditation and care coordination improves patient outcomes in CVS and is a useful adjunct to standard treatment. Studies to determine the independent effects of meditation and care coordination are warranted.
    MeSH term(s) Adaptation, Psychological ; Adult ; Female ; Humans ; Integrative Medicine/methods ; Male ; Meditation ; Prospective Studies ; Treatment Outcome ; Vomiting/psychology ; Vomiting/therapy
    Language English
    Publishing date 2021-03-28
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14132
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Wide-area transepithelial sampling in adjunct to forceps biopsy increases the absolute detection rates of Barrett's oesophagus and oesophageal dysplasia: a meta-analysis and systematic review.

    Suresh Kumar, Vishnu Charan / Harne, Prateek / Patthipati, Venkata Suresh / Subedi, Abinash / Masood, Umair / Sharma, Anuj / Goyal, Faith / Aggarwal, Nancy / Sapkota, Bishnu

    BMJ open gastroenterology

    2020  Volume 7, Issue 1

    Abstract: Background: Wide-area transepithelial sampling (WATS) is a new technique that uses an abrasive brush to obtain samples from a larger surface area of the oesophagus. Studies have shown promising results that WATS in adjunct to forceps biopsy (FB) ... ...

    Abstract Background: Wide-area transepithelial sampling (WATS) is a new technique that uses an abrasive brush to obtain samples from a larger surface area of the oesophagus. Studies have shown promising results that WATS in adjunct to forceps biopsy (FB) increases the detection rate of Barrett's oesophagus (BE) as well as oesophageal dysplasia (ED). We conducted a systematic review and meta-analysis to compare the detection rates of BE and ED between FB and WATS in adjunct to FB.
    Methods: A Literature search was done using electronic databases, including PubMed, Embase, Scopus, Cochrane and CINAHL from inception to 26 April 2020. A meta-analysis comparing detection rates of WATS in adjunct to FB versus FB using the random-effects model was done using RevMan V.5.3.
    Results: Pooled data from 20 392 endoscopies across 11 studies showed an absolute increase in detection of 16% (95% CI 0.10% to 0.22%, p<0.00001). A relative increase of 1.62 was seen in detection rates of BE (95% CI 1.28 to 2.05, p<0.0001) when WATS was used with FB with the number needed to test (NNT) of 6.1 patients. For ED, a 2% absolute increase (95% CI 0.01 to 0.03, p=0.001) in additional diagnostic yield from WATS. A relative increase of 2.05 was seen in the detection rate of ED (95% CI 1.42 to 2.98, p=0.0001) yielding an NNT of 50 patients.
    Conclusion: Our study shows that WATS, as an adjunct to FB, improves both the absolute detection rate and relative detection rate of both BE and ED as compared to FB alone.
    Language English
    Publishing date 2020-09-12
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2054-4774
    ISSN 2054-4774
    DOI 10.1136/bmjgast-2020-000494
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top