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  1. Book ; Thesis: Development and characterization of a multi-modality anti PSMA targeting agent for immuno-SPECT/CT, near-infrared fluorescence imaging and targeted photoimmunotherapy of PSMA-expressing tumors

    Lütje, Susanne

    2016  

    Institution Universität Duisburg-Essen
    Author's details vorgelegt von Dr. Susanne Lütje
    Language English
    Size 77 Seiten, Illustrationen
    Publishing place Duisburg ; Essen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Duisburg-Essen, 2017
    HBZ-ID HT019435282
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Estimating the Potential of Radiomics Features and Radiomics Signature from Pretherapeutic PSMA-PET-CT Scans and Clinical Data for Prediction of Overall Survival When Treated with

    Moazemi, Sobhan / Erle, Annette / Lütje, Susanne / Gaertner, Florian C / Essler, Markus / Bundschuh, Ralph A

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 2

    Abstract: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PSMA-PET/CT) scans can facilitate diagnosis and treatment of prostate disease. Radiomics signature (RS) is widely used for the analysis of overall survival (OS) ... ...

    Abstract Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PSMA-PET/CT) scans can facilitate diagnosis and treatment of prostate disease. Radiomics signature (RS) is widely used for the analysis of overall survival (OS) in cancer diseases. This study aims at investigating the role of radiomics features (RFs) and RS from pretherapeutic gallium-68 (
    Language English
    Publishing date 2021-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11020186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Evaluating a Machine Learning Tool for the Classification of Pathological Uptake in Whole-Body PSMA-PET-CT Scans.

    Erle, Annette / Moazemi, Sobhan / Lütje, Susanne / Essler, Markus / Schultz, Thomas / Bundschuh, Ralph A

    Tomography (Ann Arbor, Mich.)

    2021  Volume 7, Issue 3, Page(s) 301–312

    Abstract: The importance of machine learning (ML) in the clinical environment increases constantly. Differentiation of pathological from physiological tracer-uptake in positron emission tomography/computed tomography (PET/CT) images is considered time-consuming ... ...

    Abstract The importance of machine learning (ML) in the clinical environment increases constantly. Differentiation of pathological from physiological tracer-uptake in positron emission tomography/computed tomography (PET/CT) images is considered time-consuming and attention intensive, hence crucial for diagnosis and treatment planning. This study aimed at comparing and validating supervised ML algorithms to classify pathological uptake in prostate cancer (PC) patients based on prostate-specific membrane antigen (PSMA)-PET/CT. Retrospective analysis of
    MeSH term(s) Humans ; Machine Learning ; Male ; Positron Emission Tomography Computed Tomography ; Prostatic Neoplasms/diagnostic imaging ; Retrospective Studies ; Whole Body Imaging
    Language English
    Publishing date 2021-07-29
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2379-139X
    ISSN (online) 2379-139X
    DOI 10.3390/tomography7030027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Radiolabeling Strategies of Nanobodies for Imaging Applications.

    Küppers, Jim / Kürpig, Stefan / Bundschuh, Ralph A / Essler, Markus / Lütje, Susanne

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 9

    Abstract: Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to ... ...

    Abstract Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to their targets after intravenous administration, while unbound molecules are quickly cleared from the circulation. In consequence, high signal-to-background ratios can be achieved, rendering radiolabeled nanobodies high-potential candidates for imaging applications in oncology, immunology and specific diseases, for instance in the cardiovascular system. In this review, a comprehensive overview of central aspects of nanobody functionalization and radiolabeling strategies is provided.
    Language English
    Publishing date 2021-08-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11091530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Für dich!

    Bougaeva, Sonja / Lütje, Susanne

    [ab 18 Monaten]

    2015  

    Author's details Sonja Bougaeva; Susanne Lütje
    Language German
    Size [8] Bl., überw. Ill., 170 mm x 170 mm
    Publisher Oetinger
    Publishing place Hamburg
    Document type Book
    ISBN 3789175609 ; 9783789175602
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Das kleine Schwein ist nicht allein

    Hammerle, Nina / Lütje, Susanne

    [ab 2 Jahren]

    2015  

    Author's details Nina Hammerle; Susanne Lütje
    Language German
    Size [8] Bl., überw. Ill.
    Publisher Oetinger
    Publishing place Hamburg
    Document type Book
    ISBN 378917937X ; 9783789179372
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book: Wibo Waschbär räumt auf

    Hebrock, Andrea / Lütje, Susanne

    2014  

    Author's details Andrea Hebrock; Susanne Lütje
    Keywords Aufräumen
    Language German
    Size [7] Bl., überw. Ill.
    Publisher Oetinger
    Publishing place Hamburg
    Document type Book
    ISBN 3789166375 ; 9783789166372
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book: Wibo Waschbär am Meer

    Hebrock, Andrea / Lütje, Susanne

    2014  

    Author's details Susanne Lütje
    Keywords Badeurlaub
    Language German
    Size [7] Bl., überw. Ill.
    Publisher Oetinger
    Publishing place Hamburg
    Document type Book
    ISBN 3789166367 ; 9783789166365
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article: Therapy of Patients with Neuroendocrine Neoplasia-Evidence-Based Approaches and New Horizons.

    Bundschuh, Ralph A / Habacha, Bilel / Lütje, Susanne / Essler, Markus

    Journal of clinical medicine

    2019  Volume 8, Issue 9

    Abstract: Neuroendocrine tumors (NETs) show low but increasing incidence and originate in multiple organs, including the pancreas, midgut, caecum, rectum, appendix, colon, and lungs. Due to their stunning genetic, histological, and clinical variability, diagnosis ... ...

    Abstract Neuroendocrine tumors (NETs) show low but increasing incidence and originate in multiple organs, including the pancreas, midgut, caecum, rectum, appendix, colon, and lungs. Due to their stunning genetic, histological, and clinical variability, diagnosis and treatment of NETs are challenging. In addition, low incidence and high variability hamper the implementation of high evidence trials. Therefore, guidelines do not cover the complexity of NETs and, frequently, treatment decisions are taken by interdisciplinary tumor conferences at comprehensive cancer centers. Treatment aims are (i) control of tumor growth, (ii) symptom control, as well as (iii) the improvement of progression-free survival (PFS) and overall survival (OS). Here, we discuss high evidence trials facilitating the achievement of these treatment aims. The majority of the evidence exists for treatment with somatostatin analogue, everolimus, peptide receptor radionuclide therapy (PRRT) with
    Language English
    Publishing date 2019-09-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm8091474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Die liebste Mama der Welt!

    Lütje, Susanne / Zabini, Eleni

    2014  

    Author's details Susanne Lütje; Eleni Zabini
    Keywords Mutterliebe ; Jungtiere
    Language German
    Size Online-Ressource ([19] S.), überw. Ill.
    Publisher Oetinger
    Publishing place Hamburg
    Document type Book ; Online
    ISBN 9783862745142 ; 3862745147
    Database Former special subject collection: coastal and deep sea fishing

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